标题
Mechanistic studies of a small-molecule modulator of SMN2 splicing
作者
关键词
-
出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 115, Issue 20, Pages E4604-E4612
出版商
Proceedings of the National Academy of Sciences
发表日期
2018-05-01
DOI
10.1073/pnas.1800260115
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Small molecules against RNA targets attract big backers
- (2017) Asher Mullard NATURE REVIEWS DRUG DISCOVERY
- Small molecule-mediated inhibition of myofibroblast transdifferentiation for the treatment of fibrosis
- (2017) Michael J. Bollong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Binding to SMN2 pre-mRNA-protein complex elicits specificity for small molecule splicing modifiers
- (2017) Manaswini Sivaramakrishnan et al. Nature Communications
- Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain
- (2017) Nathanael G. Lintner et al. PLOS BIOLOGY
- Inforna 2.0: A Platform for the Sequence-Based Design of Small Molecules Targeting Structured RNAs
- (2016) Matthew D. Disney et al. ACS Chemical Biology
- Approaches to Validate and Manipulate RNA Targets with Small Molecules in Cells
- (2016) Jessica L. Childs-Disney et al. Annual Review of Pharmacology and Toxicology
- Design of a small molecule against an oncogenic noncoding RNA
- (2016) Sai Pradeep Velagapudi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibition of Non-ATG Translational Events in Cells via Covalent Small Molecules Targeting RNA
- (2015) Wang-Yong Yang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Selective small-molecule inhibition of an RNA structural element
- (2015) John A. Howe et al. NATURE
- Structural imprints in vivo decode RNA regulatory mechanisms
- (2015) Robert C. Spitale et al. NATURE
- SMN2 splice modulators enhance U1–pre-mRNA association and rescue SMA mice
- (2015) James Palacino et al. Nature Chemical Biology
- Selective 2′-hydroxyl acylation analyzed by primer extension and mutational profiling (SHAPE-MaP) for direct, versatile and accurate RNA structure analysis
- (2015) Matthew J Smola et al. Nature Protocols
- FUBP1: a new protagonist in splicing regulation of the DMD gene
- (2015) Julie Miro et al. NUCLEIC ACIDS RESEARCH
- The Splicing Factor FUBP1 Is Required for the Efficient Splicing of OncogeneMDM2Pre-mRNA
- (2014) Aishwarya G. Jacob et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The cellular thermal shift assay for evaluating drug target interactions in cells
- (2014) Rozbeh Jafari et al. Nature Protocols
- Targeting SR Proteins Improves SMN Expression in Spinal Muscular Atrophy Cells
- (2014) Claribel D. Wee et al. PLoS One
- SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy
- (2014) N. A. Naryshkin et al. SCIENCE
- Antitumor activity of a pyrrole-imidazole polyamide
- (2013) F. Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Far upstream element-binding protein 1 and RNA secondary structure both mediate second-step splicing repression
- (2013) H. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay
- (2013) D. M. Molina et al. SCIENCE
- A Stem Cell-Based Approach to Cartilage Repair
- (2012) K. Johnson et al. SCIENCE
- Spinal Muscular Atrophy
- (2011) Stephen J. Kolb ARCHIVES OF NEUROLOGY
- A screen for regulators of survival of motor neuron protein levels
- (2011) Nina R Makhortova et al. Nature Chemical Biology
- Spinal muscular atrophy
- (2011) Adele D'Amico et al. Orphanet Journal of Rare Diseases
- Antisense correction of SMN2 splicing in the CNS rescues necrosis in a type III SMA mouse model
- (2010) Y. Hua et al. GENES & DEVELOPMENT
- The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs
- (2009) Michele Trabucchi et al. NATURE
- MEME SUITE: tools for motif discovery and searching
- (2009) T. L. Bailey et al. NUCLEIC ACIDS RESEARCH
- Spinal muscular atrophy
- (2008) Mitchell R Lunn et al. LANCET
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