SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy
出版年份 2014 全文链接
标题
SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy
作者
关键词
-
出版物
SCIENCE
Volume 345, Issue 6197, Pages 688-693
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2014-08-08
DOI
10.1126/science.1250127
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Pathological impact ofSMN2mis-splicing in adult SMA mice
- (2013) Kentaro Sahashi et al. EMBO Molecular Medicine
- A possible new mechanism for the control of miRNA expression in neurons
- (2013) Erika Reime Kinjo et al. EXPERIMENTAL NEUROLOGY
- An intronic structure enabled by a long-distance interaction serves as a novel target for splicing correction in spinal muscular atrophy
- (2013) Natalia N. Singh et al. NUCLEIC ACIDS RESEARCH
- Spinal muscular atrophy: The role of SMN in axonal mRNA regulation
- (2012) Claudia Fallini et al. BRAIN RESEARCH
- Characterization of behavioral and neuromuscular junction phenotypes in a novel allelic series of SMA mouse models
- (2012) Melissa Osborne et al. HUMAN MOLECULAR GENETICS
- A Quantitative High-Throughput In Vitro Splicing Assay Identifies Inhibitors of Spliceosome Catalysis
- (2012) M. G. Berg et al. MOLECULAR AND CELLULAR BIOLOGY
- Fast gapped-read alignment with Bowtie 2
- (2012) Ben Langmead et al. NATURE METHODS
- Evaluation of SMN Protein, Transcript, and Copy Number in the Biomarkers for Spinal Muscular Atrophy (BforSMA) Clinical Study
- (2012) Thomas O. Crawford et al. PLoS One
- Spinal Muscular Atrophy
- (2011) Stephen J. Kolb ARCHIVES OF NEUROLOGY
- New Therapeutic Approaches to Spinal Muscular Atrophy
- (2011) Aga Lewelt et al. Current Neurology and Neuroscience Reports
- Pan-ethnic carrier screening and prenatal diagnosis for spinal muscular atrophy: clinical laboratory analysis of >72 400 specimens
- (2011) Elaine A Sugarman et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Severe neuromuscular denervation of clinically relevant muscles in a mouse model of spinal muscular atrophy
- (2011) K. K. Y. Ling et al. HUMAN MOLECULAR GENETICS
- Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model
- (2011) Yimin Hua et al. NATURE
- A screen for regulators of survival of motor neuron protein levels
- (2011) Nina R Makhortova et al. Nature Chemical Biology
- Spinal Muscular Atrophy: A Clinical and Research Update
- (2011) Jennifer A. Markowitz et al. PEDIATRIC NEUROLOGY
- Small Molecule Amiloride Modulates Oncogenic RNA Alternative Splicing to Devitalize Human Cancer Cells
- (2011) Jan-Gowth Chang et al. PLoS One
- Alternative splicing in spinal muscular atrophy underscores the role of an intron definition model
- (2011) Natalia N. Singh et al. RNA Biology
- Antisense Oligonucleotides Delivered to the Mouse CNS Ameliorate Symptoms of Severe Spinal Muscular Atrophy
- (2011) M. A. Passini et al. Science Translational Medicine
- Identification of SAP155 as the Target of GEX1A (Herboxidiene), an Antitumor Natural Product
- (2010) Makoto Hasegawa et al. ACS Chemical Biology
- Fast and SNP-tolerant detection of complex variants and splicing in short reads
- (2010) T. D. Wu et al. BIOINFORMATICS
- A degron created by SMN2 exon 7 skipping is a principal contributor to spinal muscular atrophy severity
- (2010) S. Cho et al. GENES & DEVELOPMENT
- A comprehensive survey of 3' animal miRNA modification events and a possible role for 3' adenylation in modulating miRNA targeting effectiveness
- (2010) A. M. Burroughs et al. GENOME RESEARCH
- Rapid-Response Splicing Reporter Screens Identify Differential Regulators of Constitutive and Alternative Splicing
- (2010) I. Younis et al. MOLECULAR AND CELLULAR BIOLOGY
- MicroRNA assassins: factors that regulate the disappearance of miRNAs
- (2010) Zoya S Kai et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- A population-based study of genotypic and phenotypic variability in children with spinal muscular atrophy
- (2009) Eva Arkblad et al. ACTA PAEDIATRICA
- Evidence for the Involvement of Human DNA Polymerase N in the Repair of DNA Interstrand Cross-Links
- (2009) Laura Zietlow et al. BIOCHEMISTRY
- The Sequence Alignment/Map format and SAMtools
- (2009) H. Li et al. BIOINFORMATICS
- Selective stabilization of mammalian microRNAs by 3' adenylation mediated by the cytoplasmic poly(A) polymerase GLD-2
- (2009) T. Katoh et al. GENES & DEVELOPMENT
- DNA Polymerase POLN Participates in Cross-Link Repair and Homologous Recombination
- (2009) G.-L. Moldovan et al. MOLECULAR AND CELLULAR BIOLOGY
- Spinal muscular atrophy: why do low levels of survival motor neuron protein make motor neurons sick?
- (2009) Arthur H. M. Burghes et al. NATURE REVIEWS NEUROSCIENCE
- The Biflavonoid Isoginkgetin Is a General Inhibitor of Pre-mRNA Splicing
- (2008) Kristine O'Brien et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of SMN Protein Stability
- (2008) B. G. Burnett et al. MOLECULAR AND CELLULAR BIOLOGY
- Mapping and quantifying mammalian transcriptomes by RNA-Seq
- (2008) Ali Mortazavi et al. NATURE METHODS
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