miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregationin vivo

Identification of miRNA Changes in Alzheimer's Disease Brain and CSF Yields Putative Biomarkers and Insights into Disease Pathways

(2017) John P. Cogswell et al.   JOURNAL OF ALZHEIMERS DISEASE

Frontotemporal Dementia Phenotype Associated with MAPT Gene Duplication

(2017) Anne Rovelet-Lecrux et al.   JOURNAL OF ALZHEIMERS DISEASE

Plasma microRNA biomarkers for detection of mild cognitive impairment

(2016) Kira S. Sheinerman et al.   Aging-US

Plasma microRNA biomarkers for detection of mild cognitive impairment: Biomarker Validation Study

(2016) Kira S. Sheinerman et al.   Aging-US

Early etiology of Alzheimer’s disease: tipping the balance toward autophagy or endosomal dysfunction?

(2015) Aleksandar Peric et al.   ACTA NEUROPATHOLOGICA

Memory formation and retention are affected in adult miR-132/212 knockout mice

(2015) Julia Hernandez-Rapp et al.   BEHAVIOURAL BRAIN RESEARCH

MicroRNA-138 promotes tau phosphorylation by targeting retinoic acid receptor alpha

(2015) Xiong Wang et al.   FEBS LETTERS

Dysregulation of microRNA-219 promotes neurodegeneration through post-transcriptional regulation of tau

(2015) Ismael Santa-Maria et al.   JOURNAL OF CLINICAL INVESTIGATION

mTOR signaling in aging and neurodegeneration: At the crossroad between metabolism dysfunction and impairment of autophagy

(2015) Marzia Perluigi et al.   NEUROBIOLOGY OF DISEASE

The biological functions of miRNAs: lessons from in vivo studies

(2015) Joana A. Vidigal et al.   TRENDS IN CELL BIOLOGY

MicroRNA-125b induces tau hyperphosphorylation and cognitive deficits in Alzheimer's disease

(2014) J. Banzhaf-Strathmann et al.   EMBO JOURNAL

The Gene Silencing Transcription Factor REST Represses miR-132 Expression in Hippocampal Neurons Destined to Die

(2014) Jee-Yeon Hwang et al.   JOURNAL OF MOLECULAR BIOLOGY

Models of β-amyloid induced Tau-pathology: the long and “folded” road to understand the mechanism

(2014) Ilie-Cosmin Stancu et al.   Molecular Neurodegeneration

Huntington's disease is a four-repeat tauopathy with tau nuclear rods

(2014) Marta Fernández-Nogales et al.   NATURE MEDICINE

MicroRNA-922 promotes tau phosphorylation by downregulating ubiquitin carboxy-terminal hydrolase L1 (UCHL1) expression in the pathogenesis of Alzheimer’s disease

(2014) Z.-B. Zhao et al.   NEUROSCIENCE

Nrf2 reduces levels of phosphorylated tau protein by inducing autophagy adaptor protein NDP52

(2014) Chulman Jo et al.   Nature Communications

Association of MAPT haplotypes with Alzheimer’s disease risk and MAPT brain gene expression levels

(2014) Mariet Allen et al.   Alzheimers Research & Therapy

MicroRNAs targeting Nicastrin regulate Aβ production and are affected by target site polymorphisms

(2014) Charlotte Delay et al.   Frontiers in Molecular Neuroscience

MicroRNAs in brain development and function: a matter of flexibility and stability

(2014) Philipp Follert et al.   Frontiers in Molecular Neuroscience

Interaction of transactive response DNA binding protein 43 with nuclear factor κB in mild cognitive impairment with episodic memory deficits

(2014) Yasuyuki Ohta et al.   Acta Neuropathologica Communications

mTOR regulates tau phosphorylation and degradation: implications for Alzheimer's disease and other tauopathies

(2013) Antonella Caccamo et al.   AGING CELL

Alteration of the microRNA network during the progression of Alzheimer's disease

(2013) Pierre Lau et al.   EMBO Molecular Medicine

Motor neuron disease and frontotemporal dementia: sometimes related, sometimes not

(2013) John Hardy et al.   EXPERIMENTAL NEUROLOGY

In vivoknockdown of hippocampal miR-132 expression impairs memory acquisition of trace fear conditioning

(2013) Ruo-Yu Wang et al.   HIPPOCAMPUS

Method for widespread microRNA-155 inhibition prolongs survival in ALS-model mice

(2013) Erica D. Koval et al.   HUMAN MOLECULAR GENETICS

De-repression of FOXO3a death axis by microRNA-132 and -212 causes neuronal apoptosis in Alzheimer's disease

(2013) Hon-Kit Andus Wong et al.   HUMAN MOLECULAR GENETICS

Alternative polyadenylation and miR-34 family members regulate tau expression

(2013) John R. Dickson et al.   JOURNAL OF NEUROCHEMISTRY

Rare autosomal copy number variations in early-onset familial Alzheimer’s disease

(2013) B V Hooli et al.   MOLECULAR PSYCHIATRY

Identification of differentially expressed microRNAs across the developing human brain

(2013) M N Ziats et al.   MOLECULAR PSYCHIATRY

The role of autophagy in neurodegenerative disease

(2013) Ralph A Nixon   NATURE MEDICINE

Endogenous murine tau promotes neurofibrillary tangles in 3xTg-AD mice without affecting cognition

(2013) David Baglietto-Vargas et al.   NEUROBIOLOGY OF DISEASE

Rapamycin Attenuates the Progression of Tau Pathology in P301S Tau Transgenic Mice

(2013) Sefika Ozcelik et al.   PLoS One

miR-132/212 Knockout Mice Reveal Roles for These miRNAs in Regulating Cortical Synaptic Transmission and Plasticity

(2013) Judit Remenyi et al.   PLoS One

Systemic dysregulation of TDP-43 binding microRNAs in amyotrophic lateral sclerosis

(2013) Axel Freischmidt et al.   Acta Neuropathologica Communications

The downward spiral of tau and autolysosomes

(2012) Suren S. Ambegaokar et al.   Autophagy

Copy number variations involving the microtubule-associated protein tau in human diseases: Figure 1

(2012) Anne Rovelet-Lecrux et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Deregulation of Protein Phosphatase 2A and Hyperphosphorylation of   Protein Following Onset of Diabetes in NOD Mice

(2012) M.-A. Papon et al.   DIABETES

TMEM106B, the Risk Gene for Frontotemporal Dementia, Is Regulated by the microRNA-132/212 Cluster and Affects Progranulin Pathways

(2012) A. S. Chen-Plotkin et al.   JOURNAL OF NEUROSCIENCE

MicroRNAs in Alzheimer's disease

(2012) Charlotte Delay et al.   NEUROBIOLOGY OF DISEASE

Propagation of Tau Pathology in a Model of Early Alzheimer's Disease

(2012) Alix de Calignon et al.   NEURON

miR-212/132 expression and functions: within and beyond the neuronal compartment

(2012) A. Wanet et al.   NUCLEIC ACIDS RESEARCH

Gene Network and Pathway Analysis of Mice with Conditional Ablation of Dicer in Post-Mitotic Neurons

(2012) Véronique Dorval et al.   PLoS One

MicroRNA-132 dysregulation in schizophrenia has implications for both neurodevelopment and adult brain function

(2012) B. H. Miller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNAs and neurodegeneration: role and impact

(2012) Masashi Abe et al.   TRENDS IN CELL BIOLOGY

The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy

(2012) Ahmet Ucar et al.   Nature Communications

MicroRNA-132 loss is associated with tau exon 10 inclusion in progressive supranuclear palsy

(2011) Pascal Y. Smith et al.   HUMAN MOLECULAR GENETICS

Patterns of microRNA expression in normal and early Alzheimer’s disease human temporal cortex: white matter versus gray matter

(2010) Wang-Xia Wang et al.   ACTA NEUROPATHOLOGICA

The cholinergic system in aging and neuronal degeneration

(2010) Reinhard Schliebs et al.   BEHAVIOURAL BRAIN RESEARCH

Regulation of the miR-212/132 locus by MSK1 and CREB in response to neurotrophins

(2010) Judit Remenyi et al.   BIOCHEMICAL JOURNAL

Altered microRNA regulation in Huntington's disease models

(2010) Soon-Tae Lee et al.   EXPERIMENTAL NEUROLOGY

Genetic ablation of Dicer in adult forebrain neurons results in abnormal tau hyperphosphorylation and neurodegeneration

(2010) Sébastien S. Hébert et al.   HUMAN MOLECULAR GENETICS

Desperately seeking microRNA targets

(2010) Marshall Thomas et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dicer1 and miR-219 Are Required for Normal Oligodendrocyte Differentiation and Myelination

(2010) Jason C. Dugas et al.   NEURON

MicroRNA132 Modulates Short-Term Synaptic Plasticity but Not Basal Release Probability in Hippocampal Neurons

(2010) Talley J. Lambert et al.   PLoS One

microRNA-132 regulates dendritic growth and arborization of newborn neurons in the adult hippocampus

(2010) S. T. Magill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Partial deletion of theMAPTgene: A novel mechanism of FTDP-17

(2009) Anne Rovelet-Lecrux et al.   HUMAN MUTATION

MicroRNA-132 Potentiates Cholinergic Anti-Inflammatory Signaling by Targeting Acetylcholinesterase

(2009) Iftach Shaked et al.   IMMUNITY

Argonaute HITS-CLIP decodes microRNA–mRNA interaction maps

(2009) Sung Wook Chi et al.   NATURE

Glucocorticoid attenuates brain-derived neurotrophic factor-dependent upregulation of glutamate receptors via the suppression of microRNA-132 expression

(2009) H. Kawashima et al.   NEUROSCIENCE

Tau as a biomarker of neurodegenerative diseases

(2008) Susanna Schraen-Maschke et al.   Biomarkers in Medicine

Decreased drebrin mRNA expression in Alzheimer disease: Correlation with tau pathology

(2008) Carl Julien et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Tau exon 10 alternative splicing and tauopathies

(2008) Fei Liu et al.   Molecular Neurodegeneration

Animal models of Alzheimer's disease and frontotemporal dementia

(2008) Jürgen Götz et al.   NATURE REVIEWS NEUROSCIENCE

MicroRNA regulation of Alzheimer's Amyloid precursor protein expression

(2008) Sébastien S. Hébert et al.   NEUROBIOLOGY OF DISEASE

Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/ -secretase expression

(2008) S. S. Hebert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP

(2008) Gary A. Wayman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA