Nrf2 reduces levels of phosphorylated tau protein by inducing autophagy adaptor protein NDP52

Does bafilomycin A1block the fusion of autophagosomes with lysosomes?

(2014) Daniel J. Klionsky et al.   Autophagy

Autophagy inhibition promotes defective neosynthesized proteins storage in ALIS, and induces redirection toward proteasome processing and MHCI-restricted presentation

(2012) Till Wenger et al.   Autophagy

Extracellular M. tuberculosis DNA Targets Bacteria for Autophagy by Activating the Host DNA-Sensing Pathway

(2012) Robert O. Watson et al.   CELL

Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion

(2012) Teresa L. M. Thurston et al.   NATURE

Autophagy receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome

(2012) David A. Tumbarello et al.   NATURE CELL BIOLOGY

Long-term oral lithium treatment attenuates motor disturbance in tauopathy model mice: Implications of autophagy promotion

(2012) Kohei Shimada et al.   NEUROBIOLOGY OF DISEASE

Abnormalities of NBR1, a novel autophagy-associated protein, in muscle fibers of sporadic inclusion-body myositis

(2011) Carla D’Agostino et al.   ACTA NEUROPATHOLOGICA

Selective autophagy mediated by autophagic adapter proteins

(2011) Terje Johansen et al.   Autophagy

Regulation of Toll-like receptor signaling by NDP52-mediated selective autophagy is normally inactivated by A20

(2011) Megumi Inomata et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

p62 and NDP52 Proteins Target IntracytosolicShigellaandListeriato Different Autophagy Pathways

(2011) Serge Mostowy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p62/SQSTM1 in autophagic clearance of a non-ubiquitylated substrate

(2011) Y. Watanabe et al.   JOURNAL OF CELL SCIENCE

Autophagic degradation of tau in primary neurons and its enhancement by trehalose

(2011) Ulrike Krüger et al.   NEUROBIOLOGY OF AGING

Emerging role of p62/sequestosome-1 in the pathogenesis of Alzheimer's disease

(2011) Antero Salminen et al.   PROGRESS IN NEUROBIOLOGY

Ubiquitin: Same Molecule, Different Degradation Pathways

(2010) Michael J. Clague et al.   CELL

Small molecule modulators of antioxidant response pathway

(2010) Wooyoung Hur et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Targeting Tau Protein in Alzheimerʼs Disease

(2010) Cheng-Xin Gong et al.   DRUGS & AGING

A Caspase Cleaved Form of Tau Is Preferentially Degraded through the Autophagy Pathway

(2010) Philip J. Dolan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p62/SQSTM1Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription

(2010) Ashish Jain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease

(2010) Lars M. Ittner et al.   NATURE REVIEWS NEUROSCIENCE

Lysosomal Dysfunction Promotes Cleavage and Neurotoxicity of Tau In Vivo

(2010) Vikram Khurana et al.   PLoS Genetics

Alzheimer's Disease: From Pathology to Therapeutic Approaches

(2009) Roland Jakob-Roetne et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing

(2009) Yipeng Wang et al.   HUMAN MOLECULAR GENETICS

The Cochaperone BAG2 Sweeps Paired Helical Filament- Insoluble Tau from the Microtubule

(2009) D. C. Carrettiero et al.   JOURNAL OF NEUROSCIENCE

A Role for NBR1 in Autophagosomal Degradation of Ubiquitinated Substrates

(2009) Vladimir Kirkin et al.   MOLECULAR CELL

The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria

(2009) Teresa L M Thurston et al.   NATURE IMMUNOLOGY

Intrahippocampal injection of a lentiviral vector expressing Nrf2 improves spatial learning in a mouse model of Alzheimer's disease

(2009) K. Kanninen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagic-lysosomal perturbation enhances tau aggregation in transfectants with induced wild-type tau expression

(2008) Tadanori Hamano et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Genetic inactivation of p62 leads to accumulation of hyperphosphorylated tau and neurodegeneration

(2008) J. Ramesh Babu et al.   JOURNAL OF NEUROCHEMISTRY