Therapeutic approaches for cardiac regeneration and repair

VEGF nanoparticles repair the heart after myocardial infarction

(2018) Yasin Oduk et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration

(2018) Tamer M.A. Mohamed et al.   CELL

Direct In Vivo Reprogramming with Sendai Virus Vectors Improves Cardiac Function after Myocardial Infarction

(2018) Kazutaka Miyamoto et al.   Cell Stem Cell

Translational Research in Cardiovascular RepairTake-Home Messages

(2018) Steven A.J. Chamuleau et al.   CIRCULATION RESEARCH

Immunologic targeting of CD30 eliminates tumourigenic human pluripotent stem cells, allowing safer clinical application of hiPSC-based cell therapy

(2018) Nagako Sougawa et al.   Scientific Reports

Correction of diverse muscular dystrophy mutations in human engineered heart muscle by single-site genome editing

(2018) Chengzu Long et al.   Science Advances

ZNF281 enhances cardiac reprogramming by modulating cardiac and inflammatory gene expression

(2017) Huanyu Zhou et al.   GENES & DEVELOPMENT

Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015

(2017) Gregory A. Roth et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Single-cell transcriptomics reconstructs fate conversion from fibroblast to cardiomyocyte

(2017) Ziqing Liu et al.   NATURE

Hippo pathway deficiency reverses systolic heart failure after infarction

(2017) John P. Leach et al.   NATURE

Hypoxia induces heart regeneration in adult mice

(2017) Yuji Nakada et al.   NATURE

The extracellular matrix protein agrin promotes heart regeneration in mice

(2017) Elad Bassat et al.   NATURE

Redefining the identity of cardiac fibroblasts

(2017) Michelle D. Tallquist et al.   Nature Reviews Cardiology

Blockade to pathological remodeling of infarcted heart tissue using a porcupine antagonist

(2017) Jesung Moon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-cut genome editing restores dystrophin expression in a new mouse model of muscular dystrophy

(2017) Leonela Amoasii et al.   Science Translational Medicine

Notch Inhibition Enhances Cardiac Reprogramming by Increasing MEF2C Transcriptional Activity

(2017) Maria Abad et al.   Stem Cell Reports

Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Encapsulating Bioactive Hydrogels Improve Rat Heart Function Post Myocardial Infarction

(2017) Andre Chow et al.   Stem Cell Reports

Efficient Large-Scale 2D Culture System for Human Induced Pluripotent Stem Cells and Differentiated Cardiomyocytes

(2017) Shugo Tohyama et al.   Stem Cell Reports

Sustained miRNA delivery from an injectable hydrogel promotes cardiomyocyte proliferation and functional regeneration after ischaemic injury

(2017) Leo L. Wang et al.   Nature Biomedical Engineering

Bmi1 Is a Key Epigenetic Barrier to Direct Cardiac Reprogramming

(2016) Yang Zhou et al.   Cell Stem Cell

A Single CRISPR-Cas9 Deletion Strategy that Targets the Majority of DMD Patients Restores Dystrophin Function in hiPSC-Derived Muscle Cells

(2016) Courtney S. Young et al.   Cell Stem Cell

Lineage Reprogramming of Fibroblasts into Proliferative Induced Cardiac Progenitor Cells by Defined Factors

(2016) Pratik A. Lalit et al.   Cell Stem Cell

Targeted Epigenetic Remodeling of Endogenous Loci by CRISPR/Cas9-Based Transcriptional Activators Directly Converts Fibroblasts to Neuronal Cells

(2016) Joshua B. Black et al.   Cell Stem Cell

Chemical Enhancement of In Vitro and In Vivo Direct Cardiac ReprogrammingClinical Perspective

(2016) Tamer M. A. Mohamed et al.   CIRCULATION

Repeated Administrations of Cardiac Progenitor Cells Are Markedly More Effective Than a Single AdministrationNovelty and Significance

(2016) Yukichi Tokita et al.   CIRCULATION RESEARCH

Translation of Human-Induced Pluripotent Stem Cells

(2016) Nazish Sayed et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Allogeneic transplantation of iPS cell-derived cardiomyocytes regenerates primate hearts

(2016) Yuji Shiba et al.   NATURE

Pitx2 promotes heart repair by activating the antioxidant response after cardiac injury

(2016) Ge Tao et al.   NATURE

Genome editing in cardiovascular diseases

(2016) Alanna Strong et al.   Nature Reviews Cardiology

Novel therapeutic strategies targeting fibroblasts and fibrosis in heart disease

(2016) Robert G. Gourdie et al.   NATURE REVIEWS DRUG DISCOVERY

Conversion of human fibroblasts into functional cardiomyocytes by small molecules

(2016) Nan Cao et al.   SCIENCE

Cardiac repair in guinea pigs with human engineered heart tissue from induced pluripotent stem cells

(2016) F. Weinberger et al.   Science Translational Medicine

Genetic lineage tracing defines myofibroblast origin and function in the injured heart

(2016) Onur Kanisicak et al.   Nature Communications

Catheter-based Intramyocardial Injection of FGF1 or NRG1-loaded MPs Improves Cardiac Function in a Preclinical Model of Ischemia-Reperfusion

(2016) Elisa Garbayo et al.   Scientific Reports

The Pathogenesis and Therapy of Muscular Dystrophies

(2015) Simon Guiraud et al.   Annual Review of Genomics and Human Genetics

miR-222 Is Necessary for Exercise-Induced Cardiac Growth and Protects against Pathological Cardiac Remodeling

(2015) Xiaojun Liu et al.   Cell Metabolism

Perivascular Gli1+ Progenitors Are Key Contributors to Injury-Induced Organ Fibrosis

(2015) Rafael Kramann et al.   Cell Stem Cell

Functional Recovery of a Human Neonatal Heart After Severe Myocardial InfarctionNovelty and Significance

(2015) Bernhard J. Haubner et al.   CIRCULATION RESEARCH

Revisiting Cardiac Cellular CompositionNovelty and Significance

(2015) Alexander R. Pinto et al.   CIRCULATION RESEARCH

Direct Cardiac Reprogramming: Progress and Challenges in Basic Biology and Clinical Applications

(2015) T. Sadahiro et al.   CIRCULATION RESEARCH

Human Engineered Heart Muscles Engraft and Survive Long Term in a Rodent Myocardial Infarction ModelNovelty and Significance

(2015) Johannes Riegler et al.   CIRCULATION RESEARCH

Bone marrow-derived mesenchymal stromal cell treatment in patients with severe ischaemic heart failure: a randomized placebo-controlled trial (MSC-HF trial)

(2015) Anders Bruun Mathiasen et al.   EUROPEAN HEART JOURNAL

Heart regeneration after myocardial infarction using synthetic biomaterials

(2015) S. Pascual-Gil et al.   JOURNAL OF CONTROLLED RELEASE

Human Ventricular Unloading Induces Cardiomyocyte Proliferation

(2015) Diana C. Canseco et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Cardiac donation after circulatory death: a time to reflect

(2015) Magdi Yacoub   LANCET

ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation

(2015) Gabriele D’Uva et al.   NATURE CELL BIOLOGY

Akt1/protein kinase B enhances transcriptional reprogramming of fibroblasts to functional cardiomyocytes

(2015) Huanyu Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide inactivation of porcine endogenous retroviruses (PERVs)

(2015) L. Yang et al.   SCIENCE

Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy

(2015) C. Long et al.   SCIENCE

In vivo gene editing in dystrophic mouse muscle and muscle stem cells

(2015) M. Tabebordbar et al.   SCIENCE

In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy

(2015) C. E. Nelson et al.   SCIENCE

A microRNA-Hippo pathway that promotes cardiomyocyte proliferation and cardiac regeneration in mice

(2015) Ying Tian et al.   Science Translational Medicine

Fibroblast Growth Factors and Vascular Endothelial Growth Factor Promote Cardiac Reprogramming under Defined Conditions

(2015) Hiroyuki Yamakawa et al.   Stem Cell Reports

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

Microvesicles and exosomes for intracardiac communication

(2014) Joost P.G. Sluijter et al.   CARDIOVASCULAR RESEARCH

Extracellular vesicles from human cardiac progenitor cells inhibit cardiomyocyte apoptosis and improve cardiac function after myocardial infarction

(2014) L. Barile et al.   CARDIOVASCULAR RESEARCH

The Oxygen-Rich Postnatal Environment Induces Cardiomyocyte Cell-Cycle Arrest through DNA Damage Response

(2014) Bao N. Puente et al.   CELL

Induction of diverse cardiac cell types by reprogramming fibroblasts with cardiac transcription factors

(2014) Y.-J. Nam et al.   DEVELOPMENT

MiR-133 promotes cardiac reprogramming by directly repressing Snai1 and silencing fibroblast signatures

(2014) N. Muraoka et al.   EMBO JOURNAL

Macrophages are required for neonatal heart regeneration

(2014) Arin B. Aurora et al.   JOURNAL OF CLINICAL INVESTIGATION

Expression of concern: the SCIPIO trial

(2014) The Lancet Editors   LANCET

Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts

(2014) James J. H. Chong et al.   NATURE

c-kit+ cells minimally contribute cardiomyocytes to the heart

(2014) Jop H. van Berlo et al.   NATURE

Cell therapy for cardiac repair—lessons from clinical trials

(2014) Atta Behfar et al.   Nature Reviews Cardiology

Paradigm Shifts in Heart-Failure Therapy — A Timeline

(2014) Chana A. Sacks et al.   NEW ENGLAND JOURNAL OF MEDICINE

Angiotensin–Neprilysin Inhibition versus Enalapril in Heart Failure

(2014) John J.V. McMurray et al.   NEW ENGLAND JOURNAL OF MEDICINE

Recombinant Neuregulin 1 Does Not Activate Cardiomyocyte DNA Synthesis in Normal or Infarcted Adult Mice

(2014) Sean Reuter et al.   PLoS One

Prevention of muscular dystrophy in mice by CRISPR/Cas9-mediated editing of germline DNA

(2014) C. Long et al.   SCIENCE

Cardiac regeneration using pluripotent stem cells—Progression to large animal models

(2014) James J.H. Chong et al.   Stem Cell Research

A neonatal blueprint for cardiac regeneration

(2014) Enzo R. Porrello et al.   Stem Cell Research

Nonhuman Primate Models in Translational Regenerative Medicine

(2014) Marcel M. Daadi et al.   STEM CELLS AND DEVELOPMENT

A CRISPR/Cas9-Based System for Reprogramming Cell Lineage Specification

(2014) Syandan Chakraborty et al.   Stem Cell Reports

Exosomes as Critical Agents of Cardiac Regeneration Triggered by Cell Therapy

(2014) Ahmed Gamal-Eldin Ibrahim et al.   Stem Cell Reports

Cardiac progenitor-derived exosomes protect ischemic myocardium from acute ischemia/reperfusion injury

(2013) Lijuan Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Adult c-kitpos Cardiac Stem Cells Are Necessary and Sufficient for Functional Cardiac Regeneration and Repair

(2013) Georgina M. Ellison et al.   CELL

Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression

(2013) Lei S. Qi et al.   CELL

CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes

(2013) Luke A. Gilbert et al.   CELL

Intracoronary Injection of Bone Marrow–Derived Mononuclear Cells Early or Late After Acute Myocardial Infarction

(2013) Daniel Sürder et al.   CIRCULATION

Intracoronary Delivery of Autologous Cardiac Stem Cells Improves Cardiac Function in a Porcine Model of Chronic Ischemic Cardiomyopathy

(2013) Roberto Bolli et al.   CIRCULATION

Cell Therapy for Heart Failure

(2013) Santosh K. Sanganalmath et al.   CIRCULATION RESEARCH

mir-17–92 Cluster Is Required for and Sufficient to Induce Cardiomyocyte Proliferation in Postnatal and Adult Hearts

(2013) Jinghai Chen et al.   CIRCULATION RESEARCH

Hippo signaling impedes adult heart regeneration

(2013) T. Heallen et al.   DEVELOPMENT

Gene therapy on the move

(2013) Kerstin B. Kaufmann et al.   EMBO Molecular Medicine

Mesenchymal Stem Cell Survival in the Infarcted Heart Is Enhanced by Lentivirus Vector-Mediated Heat Shock Protein 27 Expression

(2013) Lisa M. McGinley et al.   HUMAN GENE THERAPY

Meis1 regulates postnatal cardiomyocyte cell cycle arrest

(2013) Ahmed I. Mahmoud et al.   NATURE

Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction

(2013) Lior Zangi et al.   NATURE BIOTECHNOLOGY

Heart repair by cardiac reprogramming

(2013) Young-Jae Nam et al.   NATURE MEDICINE

Mending broken hearts: cardiac development as a basis for adult heart regeneration and repair

(2013) Mei Xin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Small and large animal models in cardiac contraction research: Advantages and disadvantages

(2013) Nima Milani-Nejad et al.   PHARMACOLOGY & THERAPEUTICS

Relaxin Prevents Cardiac Fibroblast-Myofibroblast Transition via Notch-1-Mediated Inhibition of TGF-β/Smad3 Signaling

(2013) Chiara Sassoli et al.   PLoS One

Reprogramming of human fibroblasts toward a cardiac fate

(2013) Y.-J. Nam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hippo pathway effector Yap promotes cardiac regeneration

(2013) Mei Xin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of human cardiomyocyte-like cells from fibroblasts by defined factors

(2013) R. Wada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Safety and Efficacy of an Injectable Extracellular Matrix Hydrogel for Treating Myocardial Infarction

(2013) S. B. Seif-Naraghi et al.   Science Translational Medicine

Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury

(2013) Fatih Arslan et al.   Stem Cell Research

Mitochondrial dynamics in the adult cardiomyocytes: which roles for a highly specialized cell?

(2013) Jerome Piquereau et al.   Frontiers in Physiology

Direct Reprogramming of Human Fibroblasts toward a Cardiomyocyte-like State

(2013) Ji-Dong Fu et al.   Stem Cell Reports

Distinct Metabolic Flow Enables Large-Scale Purification of Mouse and Human Pluripotent Stem Cell-Derived Cardiomyocytes

(2012) Shugo Tohyama et al.   Cell Stem Cell

Administration of Cardiac Stem Cells in Patients With Ischemic Cardiomyopathy: The SCIPIO Trial: Surgical Aspects and Interim Analysis of Myocardial Function and Viability by Magnetic Resonance

(2012) A. R. Chugh et al.   CIRCULATION

Feasibility, Safety, and Therapeutic Efficacy of Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Sheets in a Porcine Ischemic Cardiomyopathy Model

(2012) M. Kawamura et al.   CIRCULATION

Induction of Cardiomyocyte-Like Cells in Infarct Hearts by Gene Transfer of Gata4, Mef2c, and Tbx5

(2012) Kohei Inagawa et al.   CIRCULATION RESEARCH

MicroRNA-Mediated In Vitro and In Vivo Direct Reprogramming of Cardiac Fibroblasts to Cardiomyocytes

(2012) Tilanthi M. Jayawardena et al.   CIRCULATION RESEARCH

Differentiation of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells to Cardiomyocytes

(2012) Christine L. Mummery et al.   CIRCULATION RESEARCH

The regenerative capacity of the zebrafish heart is dependent on TGF  signaling

(2012) F. Chablais et al.   DEVELOPMENT

Effect of Transendocardial Delivery of Autologous Bone Marrow Mononuclear Cells on Functional Capacity, Left Ventricular Function, and Perfusion in Chronic Heart Failure

(2012) Emerson C. Perin et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Effect of the Use and Timing of Bone Marrow Mononuclear Cell Delivery on Left Ventricular Function After Acute Myocardial Infarction

(2012) Jay H. Traverse et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Comparison of Allogeneic vs Autologous Bone Marrow–Derived Mesenchymal Stem Cells Delivered by Transendocardial Injection in Patients With Ischemic Cardiomyopathy

(2012) Joshua M. Hare et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

MicroRNA-214 protects the mouse heart from ischemic injury by controlling Ca2+ overload and cell death

(2012) Arin B. Aurora et al.   JOURNAL OF CLINICAL INVESTIGATION

Human Cardiac Progenitor Cells Engineered With Pim-I Kinase Enhance Myocardial Repair

(2012) Sadia Mohsin et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial

(2012) Raj R Makkar et al.   LANCET

Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts

(2012) Yuji Shiba et al.   NATURE

Heart repair by reprogramming non-myocytes with cardiac transcription factors

(2012) Kunhua Song et al.   NATURE

In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes

(2012) Li Qian et al.   NATURE

Functional screening identifies miRNAs inducing cardiac regeneration

(2012) Ana Eulalio et al.   NATURE

Myofibroblast-mediated mechanisms of pathological remodelling of the heart

(2012) Karl T. Weber et al.   Nature Reviews Cardiology

MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles

(2012) Eva van Rooij et al.   NATURE REVIEWS DRUG DISCOVERY

Transcription factors ETS2 and MESP1 transdifferentiate human dermal fibroblasts into cardiac progenitors

(2012) J. F. Islas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family

(2012) E. R. Porrello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

A double-blind, randomized, controlled, multicenter study to assess the safety and cardiovascular effects of skeletal myoblast implantation by catheter delivery in patients with chronic heart failure after myocardial infarction

(2011) Thomas J. Povsic et al.   AMERICAN HEART JOURNAL

Induced Neuronal Cells: How to Make and Define a Neuron

(2011) Nan Yang et al.   Cell Stem Cell

Wnt1/βcatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair

(2011) Jinzhu Duan et al.   EMBO JOURNAL

Adult mouse epicardium modulates myocardial injury by secreting paracrine factors

(2011) Bin Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

Novel regenerative therapy using cell-sheet covered with omentum flap delivers a huge number of cells in a porcine myocardial infarction model

(2011) Yasuhiro Shudo et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Relaxin remodels fibrotic healing following myocardial infarction

(2011) Chrishan S Samuel et al.   LABORATORY INVESTIGATION

Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial

(2011) Roberto Bolli et al.   LANCET

Heart regeneration

(2011) Michael A. Laflamme et al.   NATURE

Induction of human neuronal cells by defined transcription factors

(2011) Zhiping P. Pang et al.   NATURE

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

(2011) Lydia Alvarez-Erviti et al.   NATURE BIOTECHNOLOGY

Hippo Pathway Inhibits Wnt Signaling to Restrain Cardiomyocyte Proliferation and Heart Size

(2011) T. Heallen et al.   SCIENCE

Transient Regenerative Potential of the Neonatal Mouse Heart

(2011) E. R. Porrello et al.   SCIENCE

Large animal models for cardiac stem cell therapies

(2011) F. Gandolfi et al.   THERIOGENOLOGY

Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors

(2010) Masaki Ieda et al.   CELL

Long-Term Improvement in Postinfarct Left Ventricular Global and Regional Contractile Function Is Mediated by Embryonic Stem Cell–Derived Cardiomyocytes

(2010) Hui Qiao et al.   Circulation-Cardiovascular Imaging

MicroRNA Regulatory Networks in Cardiovascular Development

(2010) Ning Liu et al.   DEVELOPMENTAL CELL

The Hippo Signaling Pathway in Development and Cancer

(2010) Duojia Pan   DEVELOPMENTAL CELL

A Phase II, Randomized, Double-Blind, Multicenter, Based on Standard Therapy, Placebo-Controlled Study of the Efficacy and Safety of Recombinant Human Neuregulin-1 in Patients With Chronic Heart Failure

(2010) Runlin Gao et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Skeletal myoblasts for cardiac repair

(2010) Shazia Durrani et al.   Regenerative Medicine

Understanding gene circuits at cell-fate branch points for rational cell reprogramming

(2010) Joseph X. Zhou et al.   TRENDS IN GENETICS

Neuregulin1/ErbB4 Signaling Induces Cardiomyocyte Proliferation and Repair of Heart Injury

(2009) Kevin Bersell et al.   CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Mesenchymal Cell Transplantation and Myocardial Remodeling After Myocardial Infarction

(2009) J. A. Dixon et al.   CIRCULATION

Engraftment, Differentiation, and Functional Benefits of Autologous Cardiosphere-Derived Cells in Porcine Ischemic Cardiomyopathy

(2009) Peter V. Johnston et al.   CIRCULATION

Complete Genetic Correction of iPS Cells From Duchenne Muscular Dystrophy

(2009) Yasuhiro Kazuki et al.   MOLECULAR THERAPY

Variation in the safety of induced pluripotent stem cell lines

(2009) Kyoko Miura et al.   NATURE BIOTECHNOLOGY

Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs

(2009) Tian Sheng Chen et al.   NUCLEIC ACIDS RESEARCH

Allogeneic mesenchymal stem cells restore cardiac function in chronic ischemic cardiomyopathy via trilineage differentiating capacity

(2009) H. C. Quevedo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence for Cardiomyocyte Renewal in Humans

(2009) Olaf Bergmann et al.   SCIENCE

Differentiation of Embryonic Stem Cells to Clinically Relevant Populations: Lessons from Embryonic Development

(2008) Charles E. Murry et al.   CELL

The Myoblast Autologous Grafting in Ischemic Cardiomyopathy (MAGIC) Trial

(2008) Philippe Menasché et al.   CIRCULATION