Mending broken hearts: cardiac development as a basis for adult heart regeneration and repair

Type 2 Innate Signals Stimulate Fibro/Adipogenic Progenitors to Facilitate Muscle Regeneration

(2013) Jose E. Heredia et al.   CELL

Reprogramming toward Heart Regeneration: Stem Cells and Beyond

(2013) Aitor Aguirre et al.   Cell Stem Cell

Polymer-Based Restoration of Left Ventricular Mechanics

(2013) Randall J. Lee et al.   CELL TRANSPLANTATION

Regenerating new heart with stem cells

(2013) Piero Anversa et al.   JOURNAL OF CLINICAL INVESTIGATION

Induced pluripotent stem cell–derived cardiomyocytes in studies of inherited arrhythmias

(2013) Silvia G. Priori et al.   JOURNAL OF CLINICAL INVESTIGATION

Optimization of direct fibroblast reprogramming to cardiomyocytes using calcium activity as a functional measure of success

(2013) Russell C. Addis et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Macrophage Plasticity and the Role of Inflammation in Skeletal Muscle Repair

(2013) Yacine Kharraz et al.   MEDIATORS OF INFLAMMATION

Reprogramming of human fibroblasts toward a cardiac fate

(2013) Y.-J. Nam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Leukocyte Behavior in Atherosclerosis, Myocardial Infarction, and Heart Failure

(2013) F. K. Swirski et al.   SCIENCE

Signaling and Transcriptional Networks in Heart Development and Regeneration

(2013) B. G. Bruneau   Cold Spring Harbor Perspectives in Biology

Targeting Native Adult Heart Progenitors with Cardiogenic Small Molecules

(2012) Jamie L. Russell et al.   ACS Chemical Biology

Efficient Direct Reprogramming of Mature Amniotic Cells into Endothelial Cells by ETS Factors and TGFβ Suppression

(2012) Michael Ginsberg et al.   CELL

Activation of Innate Immunity Is Required for Efficient Nuclear Reprogramming

(2012) Jieun Lee et al.   CELL

Myocardial Notch Signaling Reprograms Cardiomyocytes to a Conduction-Like Phenotype

(2012) Stacey Rentschler et al.   CIRCULATION

Feasibility, Safety, and Therapeutic Efficacy of Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Sheets in a Porcine Ischemic Cardiomyopathy Model

(2012) M. Kawamura et al.   CIRCULATION

Inefficient Reprogramming of Fibroblasts into Cardiomyocytes Using Gata4, Mef2c, and Tbx5

(2012) Jenny X. Chen et al.   CIRCULATION RESEARCH

MicroRNA-Mediated In Vitro and In Vivo Direct Reprogramming of Cardiac Fibroblasts to Cardiomyocytes

(2012) Tilanthi M. Jayawardena et al.   CIRCULATION RESEARCH

The bHLH transcription factor Tcf21 is required for lineage-specific EMT of cardiac fibroblast progenitors

(2012) A. Acharya et al.   DEVELOPMENT

Distinct Compartments of the Proepicardial Organ Give Rise to Coronary Vascular Endothelial Cells

(2012) Tamar C. Katz et al.   DEVELOPMENTAL CELL

Towards regenerative therapy for cardiac disease

(2012) Leon M Ptaszek et al.   LANCET

Heart repair by reprogramming non-myocytes with cardiac transcription factors

(2012) Kunhua Song et al.   NATURE

In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes

(2012) Li Qian et al.   NATURE

Functional screening identifies miRNAs inducing cardiac regeneration

(2012) Ana Eulalio et al.   NATURE

Mammalian heart renewal by pre-existing cardiomyocytes

(2012) Samuel E. Senyo et al.   NATURE

Identification and prospective isolation of a mesothelial precursor lineage giving rise to smooth muscle cells and fibroblasts for mammalian internal organs and their vasculature

(2012) Yuval Rinkevich et al.   NATURE CELL BIOLOGY

Conversion of human fibroblasts to angioblast-like progenitor cells

(2012) Leo Kurian et al.   NATURE METHODS

Induced pluripotent stem cells: the new patient?

(2012) Milena Bellin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Molecular basis of physiological heart growth: fundamental concepts and new players

(2012) Marjorie Maillet et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Direct reprogramming of fibroblasts into endothelial cells capable of angiogenesis and reendothelialization in tissue-engineered vessels

(2012) A. Margariti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcription factors ETS2 and MESP1 transdifferentiate human dermal fibroblasts into cardiac progenitors

(2012) J. F. Islas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

YAP1, the nuclear target of Hippo signaling, stimulates heart growth through cardiomyocyte proliferation but not hypertrophy

(2012) A. von Gise et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family

(2012) E. R. Porrello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acute Inflammation Initiates the Regenerative Response in the Adult Zebrafish Brain

(2012) N. Kyritsis et al.   SCIENCE

C/EBP Transcription Factors Mediate Epicardial Activation During Heart Development and Injury

(2012) G. N. Huang et al.   SCIENCE

iPS Cell Modeling of Cardiometabolic Diseases

(2012) Kenta Nakamura et al.   Journal of Cardiovascular Translational Research

Whole-Organ Tissue Engineering: Decellularization and Recellularization of Three-Dimensional Matrix Scaffolds

(2011) Stephen F. Badylak et al.   Annual Review of Biomedical Engineering

Oncostatin M Is a Major Mediator of Cardiomyocyte Dedifferentiation and Remodeling

(2011) Thomas Kubin et al.   Cell Stem Cell

miR-15 Family Regulates Postnatal Mitotic Arrest of Cardiomyocytes

(2011) Enzo R. Porrello et al.   CIRCULATION RESEARCH

Inhibition of miR-15 Protects Against Cardiac Ischemic Injury

(2011) Thomas G. Hullinger et al.   CIRCULATION RESEARCH

tcf21+ epicardial cells adopt non-myocardial fates during zebrafish heart development and regeneration

(2011) K. Kikuchi et al.   DEVELOPMENT

Cardiac muscle regeneration: lessons from development

(2011) M. Mercola et al.   GENES & DEVELOPMENT

Efficient inducible Cre-mediated recombination in Tcf21cell lineages in the heart and kidney

(2011) Asha Acharya et al.   GENESIS

Transcriptional Suppression of Connexin43 byTBX18Undermines Cell-Cell Electrical Coupling in Postnatal Cardiomyocytes

(2011) Nidhi Kapoor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adult mouse epicardium modulates myocardial injury by secreting paracrine factors

(2011) Bin Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

Recapitulation of premature ageing with iPSCs from Hutchinson–Gilford progeria syndrome

(2011) Guang-Hui Liu et al.   NATURE

Pervasive roles of microRNAs in cardiovascular biology

(2011) Eric M. Small et al.   NATURE

Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome

(2011) Masayuki Yazawa et al.   NATURE

Heart regeneration

(2011) Michael A. Laflamme et al.   NATURE

The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal

(2011) Bin Zhao et al.   NATURE CELL BIOLOGY

Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy

(2011) Jem A. Efe et al.   NATURE CELL BIOLOGY

Hippo Pathway Inhibits Wnt Signaling to Restrain Cardiomyocyte Proliferation and Heart Size

(2011) T. Heallen et al.   SCIENCE

Transient Regenerative Potential of the Neonatal Mouse Heart

(2011) E. R. Porrello et al.   SCIENCE

Regulation of Insulin-Like Growth Factor Signaling by Yap Governs Cardiomyocyte Proliferation and Embryonic Heart Size

(2011) M. Xin et al.   Science Signaling

A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells

(2010) Maria C.N. Marchetto et al.   CELL

Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors

(2010) Masaki Ieda et al.   CELL

A Human iPSC Model of Hutchinson Gilford Progeria Reveals Vascular Smooth Muscle and Mesenchymal Stem Cell Defects

(2010) Jinqiu Zhang et al.   Cell Stem Cell

Monocytes: Protagonists of Infarct Inflammation and Repair After Myocardial Infarction

(2010) Matthias Nahrendorf et al.   CIRCULATION

Cardiomyogenesis in the Adult Human Heart

(2010) Jan Kajstura et al.   CIRCULATION RESEARCH

MicroRNA Regulatory Networks in Cardiovascular Development

(2010) Ning Liu et al.   DEVELOPMENTAL CELL

The Hippo Signaling Pathway in Development and Cancer

(2010) Duojia Pan   DEVELOPMENTAL CELL

iPS cells: A source of cardiac regeneration

(2010) Yoshinori Yoshida et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Primary contribution to zebrafish heart regeneration by gata4 + cardiomyocytes

(2010) Kazu Kikuchi et al.   NATURE

Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation

(2010) Chris Jopling et al.   NATURE

Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome

(2010) Xonia Carvajal-Vergara et al.   NATURE

Coronary arteries form by developmental reprogramming of venous cells

(2010) Kristy Red-Horse et al.   NATURE

Cell therapy for the treatment of coronary heart disease: a critical appraisal

(2010) Kai C. Wollert et al.   Nature Reviews Cardiology

Neuregulin1/ErbB4 Signaling Induces Cardiomyocyte Proliferation and Repair of Heart Injury

(2009) Kevin Bersell et al.   CELL

Electrophysiological Challenges of Cell-Based Myocardial Repair

(2009) Huei-Sheng Vincent Chen et al.   CIRCULATION

Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs

(2009) Gabsang Lee et al.   NATURE

Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors

(2009) Jun K. Takeuchi et al.   NATURE

Epicardial Control of Myocardial Proliferation and Morphogenesis

(2009) Henry M. Sucov et al.   PEDIATRIC CARDIOLOGY

Evidence for Cardiomyocyte Renewal in Humans

(2009) Olaf Bergmann et al.   SCIENCE

Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites

(2009) F. K. Swirski et al.   SCIENCE

Stem-cell-based therapy and lessons from the heart

(2008) Robert Passier et al.   NATURE

Stem-cell therapy for cardiac disease

(2008) Vincent F. M. Segers et al.   NATURE

Cardiac Plasticity

(2008) Joseph A. Hill et al.   NEW ENGLAND JOURNAL OF MEDICINE

The immune system and cardiac repair

(2008) N FRANGOGIANNIS   PHARMACOLOGICAL RESEARCH