Neuronally-directed effects of RXR activation in a mouse model of Alzheimer’s disease
出版年份 2017 全文链接
标题
Neuronally-directed effects of RXR activation in a mouse model of Alzheimer’s disease
作者
关键词
-
出版物
Scientific Reports
Volume 7, Issue 1, Pages -
出版商
Springer Nature
发表日期
2017-02-16
DOI
10.1038/srep42270
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Rescuing effects of RXR agonist bexarotene on aging-related synapse loss depend on neuronal LRP1
- (2016) Masaya Tachibana et al. EXPERIMENTAL NEUROLOGY
- Double-blind, placebo-controlled, proof-of-concept trial of bexarotene in moderate Alzheimer’s disease
- (2016) Jeffrey L. Cummings et al. Alzheimers Research & Therapy
- Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination
- (2015) Muktha S. Natrajan et al. BRAIN
- Activation of the nuclear receptor PPARδ is neuroprotective in a transgenic mouse model of Alzheimer’s disease through inhibition of inflammation
- (2015) Tarja Malm et al. Journal of Neuroinflammation
- Impaired firing properties of dentate granule neurons in an Alzheimer's disease animal model are rescued by PPARγ agonism
- (2015) Miroslav N. Nenov et al. JOURNAL OF NEUROPHYSIOLOGY
- Bexarotene-Activated Retinoid X Receptors Regulate Neuronal Differentiation and Dendritic Complexity
- (2015) A. Mounier et al. JOURNAL OF NEUROSCIENCE
- Omega-3 Fatty Acids Augment the Actions of Nuclear Receptor Agonists in a Mouse Model of Alzheimer's Disease
- (2015) B. T. Casali et al. JOURNAL OF NEUROSCIENCE
- Nuclear Receptors License Phagocytosis by Trem2+ Myeloid Cells in Mouse Models of Alzheimer's Disease
- (2015) J. C. Savage et al. JOURNAL OF NEUROSCIENCE
- Activation of RXR/PPARγ underlies neuroprotection by bexarotene in ischemic stroke
- (2015) Michelangelo Certo et al. PHARMACOLOGICAL RESEARCH
- Neuroprotective Effect of Bexarotene in the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis
- (2015) Javier Riancho et al. Frontiers in Cellular Neuroscience
- Retinoid X Receptor Agonists Inhibit Hypertension-Induced Myocardial Hypertrophy by Modulating LKB1/AMPK/p70S6K Signaling Pathway
- (2014) Jiang Zhu et al. AMERICAN JOURNAL OF HYPERTENSION
- Amyloid-β Pathology andAPOEGenotype Modulate Retinoid X Receptor Agonist Activityin Vivo
- (2014) Leon M. Tai et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Reversal of apoE4-Driven Brain Pathology and Behavioral Deficits by Bexarotene
- (2014) A. Boehm-Cagan et al. JOURNAL OF NEUROSCIENCE
- Cognitive Enhancing Treatment with a PPARγ Agonist Normalizes Dentate Granule Cell Presynaptic Function in Tg2576 APP Mice
- (2014) Miroslav N. Nenov et al. JOURNAL OF NEUROSCIENCE
- Apolipoprotein E in Synaptic Plasticity and Alzheimer’s Disease: Potential Cellular and Molecular Mechanisms
- (2014) Jaekwang Kim et al. MOLECULES AND CELLS
- Bexarotene reduces network excitability in models of Alzheimer's disease and epilepsy
- (2014) Valerie Bomben et al. NEUROBIOLOGY OF AGING
- Nuclear receptors in neurodegenerative diseases
- (2014) Rebecca Skerrett et al. NEUROBIOLOGY OF DISEASE
- More than Cholesterol Transporters: Lipoprotein Receptors in CNS Function and Neurodegeneration
- (2014) Courtney Lane-Donovan et al. NEURON
- Lysosomal Sorting of Amyloid- by the SORLA Receptor Is Impaired by a Familial Alzheimer's Disease Mutation
- (2014) S. Caglayan et al. Science Translational Medicine
- Low Dose Bexarotene Treatment Rescues Dopamine Neurons and Restores Behavioral Function in Models of Parkinson’s Disease
- (2013) Krista McFarland et al. ACS Chemical Neuroscience
- The Alzheimer’s β-secretase BACE1 localizes to normal presynaptic terminals and to dystrophic presynaptic terminals surrounding amyloid plaques
- (2013) Patty C. Kandalepas et al. ACTA NEUROPATHOLOGICA
- LXRs Regulate ER Stress and Inflammation through Dynamic Modulation of Membrane Phospholipid Composition
- (2013) Xin Rong et al. Cell Metabolism
- Autophagy failure in Alzheimer's disease and the role of defective lysosomal acidification
- (2013) Devin M. Wolfe et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Bexarotene nanocrystal—Oral and parenteral formulation development, characterization and pharmacokinetic evaluation
- (2013) Lijiang Chen et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Neuron loss in the 5XFAD mouse model of Alzheimer’s disease correlates with intraneuronal Aβ42 accumulation and Caspase-3 activation
- (2013) William A Eimer et al. Molecular Neurodegeneration
- Microglial derived tumor necrosis factor-α drives Alzheimer's disease-related neuronal cell cycle events
- (2013) Kiran Bhaskar et al. NEUROBIOLOGY OF DISEASE
- Neuroinflammation: The role and consequences
- (2013) Monty Lyman et al. NEUROSCIENCE RESEARCH
- Comment on "ApoE-Directed Therapeutics Rapidly Clear -Amyloid and Reverse Deficits in AD Mouse Models"
- (2013) N. F. Fitz et al. SCIENCE
- Comment on "ApoE-Directed Therapeutics Rapidly Clear -Amyloid and Reverse Deficits in AD Mouse Models"
- (2013) I. Tesseur et al. SCIENCE
- Comment on "ApoE-Directed Therapeutics Rapidly Clear -Amyloid and Reverse Deficits in AD Mouse Models"
- (2013) K. Veeraraghavalu et al. SCIENCE
- Inhibition of Glycogen Synthase Kinase-3 Ameliorates β-Amyloid Pathology and Restores Lysosomal Acidification and Mammalian Target of Rapamycin Activity in the Alzheimer Disease Mouse Model
- (2012) Limor Avrahami et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ApoE-Directed Therapeutics Rapidly Clear -Amyloid and Reverse Deficits in AD Mouse Models
- (2012) P. E. Cramer et al. SCIENCE
- Apolipoprotein E Promotes β-Amyloid Trafficking and Degradation by Modulating Microglial Cholesterol Levels
- (2011) C. Y. Daniel Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tumor Necrosis Factor-alpha and the Roles it Plays in Homeostatic and Degenerative Processes Within the Central Nervous System
- (2011) Sara L. Montgomery et al. Journal of Neuroimmune Pharmacology
- Mitochondrial dysfunction and accumulation of the β-secretase-cleaved C-terminal fragment of APP in Alzheimer's disease transgenic mice
- (2011) Latha Devi et al. NEUROBIOLOGY OF DISEASE
- Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations
- (2010) Ju-Hyun Lee et al. CELL
- Olfactory Dysfunction Correlates with Amyloid- Burden in an Alzheimer's Disease Mouse Model
- (2010) D. W. Wesson et al. JOURNAL OF NEUROSCIENCE
- Transgenic Mouse Models of Alzheimer's Disease
- (2010) Gregory A. Elder et al. MOUNT SINAI JOURNAL OF MEDICINE
- Mechanism of amyloid plaque formation suggests an intracellular basis of A pathogenicity
- (2010) R. P. Friedrich et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Astrocyte–neuron interactions in neurological disorders
- (2009) G. Ricci et al. JOURNAL OF BIOLOGICAL PHYSICS
- Failures to reconsolidate memory in a mouse model of Alzheimer’s disease
- (2009) Masuo Ohno NEUROBIOLOGY OF LEARNING AND MEMORY
- Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide
- (2009) X. Hu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Intracellular Aβ triggers neuron loss in the cholinergic system of the APP/PS1KI mouse model of Alzheimer's disease
- (2008) Ditte Z. Christensen et al. NEUROBIOLOGY OF AGING
- Impairments in remote memory stabilization precede hippocampal synaptic and cognitive failures in 5XFAD Alzheimer mouse model
- (2008) Ryoichi Kimura et al. NEUROBIOLOGY OF DISEASE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation