RhoA/mDia-1/profilin-1 signaling targets microvascular endothelial dysfunction in diabetic retinopathy
出版年份 2015 全文链接
标题
RhoA/mDia-1/profilin-1 signaling targets microvascular endothelial dysfunction in diabetic retinopathy
作者
关键词
RhoA, Mammalian Diaphanous homolog 1 (mDia-1), Profilin-1, Diabetic retinopathy (DR), Microvascular endothelial dysfunction (MVED)
出版物
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
Volume 253, Issue 5, Pages 669-680
出版商
Springer Nature
发表日期
2015-03-19
DOI
10.1007/s00417-015-2985-3
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Augmented expression and secretion of adipose-derived pigment epithelium-derived factor does not alter local angiogenesis or contribute to the development of systemic metabolic derangements
- (2014) Thomas V. Lakeland et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Intravascular cell delivery device for therapeutic VEGF-induced angiogenesis in chronic vascular occlusion
- (2014) Arun H.S. Kumar et al. BIOMATERIALS
- Integration of proteomic and transcriptomic profiles identifies a novel PDGF-MYC network in human smooth muscle cells
- (2014) Wei Yang et al. Cell Communication and Signaling
- Aberrant Chloride Intracellular Channel 4 Expression Contributes to Endothelial Dysfunction in Pulmonary Arterial Hypertension
- (2014) Beata Wojciak-Stothard et al. CIRCULATION
- Alternatively Spliced Tissue Factor Promotes Plaque Angiogenesis Through the Activation of Hypoxia-Inducible Factor-1α and Vascular Endothelial Growth Factor Signaling
- (2014) Chiara Giannarelli et al. CIRCULATION
- Profilin 1 is required for peripheral nervous system myelination
- (2014) L. Montani et al. DEVELOPMENT
- High Tissue Glucose Alters Intersomitic Blood Vessels in Zebrafish via Methylglyoxal Targeting the VEGF Receptor Signaling Cascade
- (2014) Kristina Jörgens et al. DIABETES
- Endoplasmic reticulum stress and endothelial dysfunction
- (2014) Stefania Lenna et al. IUBMB LIFE
- The Association of Cortactin with Profilin-1 Is Critical for Smooth Muscle Contraction
- (2014) Ruping Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Profilin-1 phosphorylation directs angiocrine expression and glioblastoma progression through HIF-1α accumulation
- (2014) Yi Fan et al. NATURE CELL BIOLOGY
- Molecular and Cellular Characterization of the Tomato Pollen Profilin, LePro1
- (2014) Long-Xi Yu et al. PLoS One
- Activated Platelets from Diabetic Rats Cause Endothelial Dysfunction by Decreasing Akt/Endothelial NO Synthase Signaling Pathway
- (2014) Keiko Ishida et al. PLoS One
- RhoA/ROCK/PTEN signaling is involved in AT-101-mediated apoptosis in human leukemia cells in vitro and in vivo
- (2014) G Li et al. Cell Death & Disease
- Mechanisms of Glioma Formation: Iterative Perivascular Glioma Growth and Invasion Leads to Tumor Progression, VEGF-Independent Vascularization, and Resistance to Antiangiogenic Therapy
- (2014) Gregory J. Baker et al. NEOPLASIA
- Rho/Rho-Associated Coiled-Coil Forming Kinase Pathway as Therapeutic Targets for Statins in Atherosclerosis
- (2013) Naoki Sawada et al. ANTIOXIDANTS & REDOX SIGNALING
- High glucose-induced apoptosis in cultured podocytes involves TRPC6-dependent calcium entry via the RhoA/ROCK pathway
- (2013) He Yang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Interaction of Profilin with the Barbed End of Actin Filaments
- (2013) Naomi Courtemanche et al. BIOCHEMISTRY
- Endothelial dysfunction — A major mediator of diabetic vascular disease
- (2013) Cristina M. Sena et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Tumor resistance to anti-VEGF therapy through up-regulation of VEGF-C expression
- (2013) Dong Li et al. CANCER LETTERS
- 14-3-3 Proteins Interact with a Hybrid Prenyl-Phosphorylation Motif to Inhibit G Proteins
- (2013) Philippe Riou et al. CELL
- Evolving Role of Microparticles in the Pathophysiology of Endothelial Dysfunction
- (2013) F. Lovren et al. CLINICAL CHEMISTRY
- The actin-binding protein profilin is required for germline stem cell maintenance and germ cell enclosure by somatic cyst cells
- (2013) A. R. Shields et al. DEVELOPMENT
- Cellular and molecular mechanisms of endothelial dysfunction in diabetes
- (2013) Anna C Roberts et al. Diabetes & Vascular Disease Research
- Visceral adipose tissue and leptin increase colonic epithelial tight junction permeability via a RhoA-ROCK-dependent pathway
- (2013) Gwenola Le Dréan et al. FASEB JOURNAL
- Continuous Blood Purification Ameliorates Endothelial Hyperpermeability in SAP Patients with MODS by Regulating Tight Junction Proteins via ROCK
- (2013) Mei Yang et al. INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS
- PDZ-RhoGEF and LARG Are Essential for Embryonic Development and Provide a Link between Thrombin and LPA Receptors and Rho Activation
- (2013) Constantinos M. Mikelis et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PKC-β Exacerbates in vitro Brain Barrier Damage in Hyperglycemic Settings via Regulation of RhoA/Rho-kinase/MLC2 Pathway
- (2013) Kirtiman Srivastava et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Minoxidil sulfate induced the increase in blood–brain tumor barrier permeability through ROS/RhoA/PI3K/PKB signaling pathway
- (2013) Yan-ting Gu et al. NEUROPHARMACOLOGY
- Crosstalk of Ras and Rho: activation of RhoA abates Kras-induced liver tumorigenesis in transgenic zebrafish models
- (2013) T W Chew et al. ONCOGENE
- The Anti-Migratory Effects of FKBPL and Its Peptide Derivative, AD-01: Regulation of CD44 and the Cytoskeletal Pathway
- (2013) Anita Yakkundi et al. PLoS One
- Mammalian Diaphanous-Related Formin 1 Regulates GSK3β-Dependent Microtubule Dynamics Required for T Cell Migratory Polarization
- (2013) Baoxia Dong et al. PLoS One
- Simvastatin Alleviates Hyperpermeability of Glomerular Endothelial Cells in Early-Stage Diabetic Nephropathy by Inhibition of RhoA/ROCK1
- (2013) Hui Peng et al. PLoS One
- E2F1 promotes angiogenesis through the VEGF-C/VEGFR-3 axis in a feedback loop for cooperative induction of PDGF-B
- (2013) David Engelmann et al. Journal of Molecular Cell Biology
- Deciphering the signaling networks underlying simvastatin-induced apoptosis in human cancer cells: evidence for non-canonical activation of RhoA and Rac1 GTPases
- (2013) Y Zhu et al. Cell Death & Disease
- RhoA modulates functional and physical interaction between ROCK1 and Erk1/2 in selenite-induced apoptosis of leukaemia cells
- (2013) F Li et al. Cell Death & Disease
- Activation of RhoA,B,C by Yersinia Cytotoxic Necrotizing Factor (CNFy) Induces Apoptosis in LNCaP Prostate Cancer Cells
- (2013) Anke Augspach et al. Toxins
- Folic acid inhibits endothelial cell migration through inhibiting the RhoA activity mediated by activating the folic acid receptor/cSrc/p190RhoGAP-signaling pathway
- (2012) Tien-Chi Hou et al. BIOCHEMICAL PHARMACOLOGY
- Small GTPase Rho regulates R-cadherin through Dia1/profilin-1
- (2012) Tabetha M. Bonacci et al. CELLULAR SIGNALLING
- Ezetimibe Improves Endothelial Function and Inhibits Rho-Kinase Activity Associated With Inhibition of Cholesterol Absorption in Humans
- (2012) Kotaro Nochioka et al. CIRCULATION JOURNAL
- Rho guanine exchange factors in blood vessels: Fine-tuners of angiogenesis and vascular function
- (2012) Jakob Nikolas Kather et al. EXPERIMENTAL CELL RESEARCH
- Endothelial Dysfunction in Diabetes Mellitus: Possible Involvement of Endoplasmic Reticulum Stress?
- (2012) Basma Basha et al. Experimental Diabetes Research
- Interleukin-8 Induces the Endothelial Cell Migration through the Activation of Phosphoinositide 3-Kinase-Rac1/RhoA Pathway
- (2012) Yi Lai et al. International Journal of Biological Sciences
- Liprin- controls stress fiber formation by binding to mDia and regulating its membrane localization
- (2012) S. Sakamoto et al. JOURNAL OF CELL SCIENCE
- RhoA mediates flow-induced endothelial sprouting in a 3-D tissue analogue of angiogenesis
- (2012) Jonathan W. Song et al. LAB ON A CHIP
- Stimulus-dependent phosphorylation of profilin-1 in angiogenesis
- (2012) Yi Fan et al. NATURE CELL BIOLOGY
- Molecular insights on context-specific role of profilin-1 in cell migration
- (2012) Zhijie Ding et al. Cell Adhesion & Migration
- Acute and sustained actions of hyperglycaemia on endothelial and glomerular barrier permeability
- (2011) P. Swärd et al. Acta Physiologica
- Masked Hypertension, Endothelial Dysfunction, and Arterial Stiffness in Type 2 Diabetes Mellitus: A Pilot Study
- (2011) K. Takeno et al. AMERICAN JOURNAL OF HYPERTENSION
- Diabetes-induced vascular dysfunction involves arginase I
- (2011) Maritza J. Romero et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- VEGF-C differentially regulates VEGF-A expression in ocular and cancer cells; promotes angiogenesis via RhoA mediated pathway
- (2011) Bharat Kumar et al. ANGIOGENESIS
- Glucosamine increases vascular contraction through activation of RhoA/Rho kinase pathway in isolated rat aorta
- (2011) Do-Hyung Kim et al. BMB Reports
- Profilin1 facilitates staurosporine-triggered apoptosis by stabilizing the integrin β1-actin complex in breast cancer cells
- (2011) Wantong Yao et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Advanced Glycation End Products Increase Permeability of Brain Microvascular Endothelial Cells through Reactive Oxygen Species–Induced Vascular Endothelial Growth Factor Expression
- (2011) Yoshimasa Niiya et al. Journal of Stroke & Cerebrovascular Diseases
- Rho-kinase inhibition ameliorates peritoneal fibrosis and angiogenesis in a rat model of peritoneal sclerosis
- (2011) N. Washida et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Fifteen formins for an actin filament: A molecular view on the regulation of human formins
- (2010) André Schönichen et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Suppression of Tumor Growth and Metastasis by Simultaneously Blocking Vascular Endothelial Growth Factor (VEGF)-A and VEGF-C with a Receptor-Immunoglobulin Fusion Protein
- (2010) D. Zhang et al. CANCER RESEARCH
- EphB-Mediated Degradation of the RhoA GEF Ephexin5 Relieves a Developmental Brake on Excitatory Synapse Formation
- (2010) Seth S. Margolis et al. CELL
- TNF- Signals Through PKC /NF- B to Alter the Tight Junction Complex and Increase Retinal Endothelial Cell Permeability
- (2010) C. A. Aveleira et al. DIABETES
- RhoA/ROCK signaling is essential for multiple aspects of VEGF-mediated angiogenesis
- (2010) Brad A. Bryan et al. FASEB JOURNAL
- Simvastatin prevents large blood pressure variability induced aggravation of cardiac hypertrophy in hypertensive rats by inhibiting RhoA/Ras–ERK pathways
- (2010) Narimasa Takayama et al. HYPERTENSION RESEARCH
- Actin in dendritic spines: connecting dynamics to function
- (2010) Pirta Hotulainen et al. JOURNAL OF CELL BIOLOGY
- Estradiol induces endothelial cell migration and proliferation through estrogen receptor-enhanced RhoA/ROCK pathway
- (2010) Pilar J. Oviedo et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Gα13 is closely related to hematopoiesis in zebrafish
- (2010) Ding Ye et al. MOLECULAR BIOLOGY REPORTS
- Glabridin, an isoflavan from licorice root, inhibits migration, invasion and angiogenesis of MDA-MB-231 human breast adenocarcinoma cells by inhibiting focal adhesion kinase/Rho signaling pathway
- (2010) Ya-Ling Hsu et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Inhibition of Rho-dependent kinases ROCK I/II activates VEGF-driven retinal neovascularization and sprouting angiogenesis
- (2009) Jens Kroll et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Spatial Coordination of Actin Polymerization and ILK–Akt2 Activity during Endothelial Cell Migration
- (2009) Yi Fan et al. DEVELOPMENTAL CELL
- Both actin and polyproline interactions of profilin-1 are required for migration, invasion and capillary morphogenesis of vascular endothelial cells
- (2009) Zhijie Ding et al. EXPERIMENTAL CELL RESEARCH
- Advanced glycation end products increase endothelial permeability through the RAGE/Rho signaling pathway
- (2009) Akiko Hirose et al. FEBS LETTERS
- Loss of RhoB Expression Enhances the Myelodysplastic Phenotype of Mammalian Diaphanous-Related Formin mDia1 Knockout Mice
- (2009) Aaron D. DeWard et al. PLoS One
- Angiopoietin-1 Prevents VEGF-Induced Endothelial Permeability by Sequestering Src through mDia
- (2008) Julie Gavard et al. DEVELOPMENTAL CELL
- RhoA/Rho-Kinase Contribute to the Pathogenesis of Diabetic Renal Disease
- (2008) F. Peng et al. DIABETES
- Rho Kinase Inhibition by Fasudil Ameliorates Diabetes-Induced Microvascular Damage
- (2008) R. Arita et al. DIABETES
- Specificity of Interactions between mDia Isoforms and Rho Proteins
- (2008) Michael Lammers et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mammalian Rho GTPases: new insights into their functions from in vivo studies
- (2008) Sarah J. Heasman et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Diabetes-induced Coronary Vascular Dysfunction Involves Increased Arginase Activity
- (2007) Maritza J. Romero et al. CIRCULATION RESEARCH
- High-resolution Structural Analysis of Mammalian Profilin 2a Complex Formation with Two Physiological Ligands: The Formin Homology 1 Domain of mDia1 and the Proline-rich Domain of VASP
- (2007) Petri Kursula et al. JOURNAL OF MOLECULAR BIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started