Perspective: Chain dynamics of unfolded and intrinsically disordered proteins from nanosecond fluorescence correlation spectroscopy combined with single-molecule FRET

Collapse Transitions of Proteins and the Interplay Among Backbone, Sidechain, and Solvent Interactions

(2018) Alex S. Holehouse et al.   Annual Review of Biophysics

Highly Disordered Amyloid- β Monomer Probed by Single-Molecule FRET and MD Simulation

(2018) Fanjie Meng et al.   BIOPHYSICAL JOURNAL

Inferring properties of disordered chains from FRET transfer efficiencies

(2018) Wenwei Zheng et al.   JOURNAL OF CHEMICAL PHYSICS

Internal friction in an intrinsically disordered protein—Comparing Rouse-like models with experiments

(2018) Andrea Soranno et al.   JOURNAL OF CHEMICAL PHYSICS

Relevance of Internal Friction and Structural Constraints for the Dynamics of Denatured Bovine Serum Albumin

(2018) Felix Ameseder et al.   Journal of Physical Chemistry Letters

Developing a molecular dynamics force field for both folded and disordered protein states

(2018) Paul Robustelli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extreme disorder in an ultrahigh-affinity protein complex

(2018) Alessandro Borgia et al.   NATURE

Combining short- and long-range fluorescence reporters with simulations to explore the intramolecular dynamics of an intrinsically disordered protein

(2017) Franziska Zosel et al.   JOURNAL OF CHEMICAL PHYSICS

Integrated view of internal friction in unfolded proteins from single-molecule FRET, contact quenching, theory, and simulations

(2017) Andrea Soranno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-Molecule FRET Spectroscopy and the Polymer Physics of Unfolded and Intrinsically Disordered Proteins

(2016) Benjamin Schuler et al.   Annual Review of Biophysics

Analysis of Fluorescence Lifetime and Energy Transfer Efficiency in Single-Molecule Photon Trajectories of Fast-Folding Proteins

(2016) Hoi Sung Chung et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Probing the Action of Chemical Denaturant on an Intrinsically Disordered Protein by Simulation and Experiment

(2016) Wenwei Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Consistent View of Polypeptide Chain Expansion in Chemical Denaturants from Multiple Experimental Methods

(2016) Alessandro Borgia et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

CHARMM36m: an improved force field for folded and intrinsically disordered proteins

(2016) Jing Huang et al.   NATURE METHODS

Comprehensive structural and dynamical view of an unfolded protein from the combination of single-molecule FRET, NMR, and SAXS

(2016) Mikayel Aznauryan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metainference: A Bayesian inference method for heterogeneous systems

(2016) M. Bonomi et al.   Science Advances

Fast infrared spectroscopy of protein dynamics: advancing sensitivity and selectivity

(2015) Klemens L Koziol et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Bayesian ensemble refinement by replica simulations and reweighting

(2015) Gerhard Hummer et al.   JOURNAL OF CHEMICAL PHYSICS

Empirical Optimization of Interactions between Proteins and Chemical Denaturants in Molecular Simulations

(2015) Wenwei Zheng et al.   Journal of Chemical Theory and Computation

Water Dispersion Interactions Strongly Influence Simulated Structural Properties of Disordered Protein States

(2015) Stefano Piana et al.   JOURNAL OF PHYSICAL CHEMISTRY B

A Method for Extracting the Free Energy Surface and Conformational Dynamics of Fast-Folding Proteins from Single Molecule Photon Trajectories

(2015) Ravishankar Ramanathan et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Single-molecule spectroscopy of protein conformational dynamics in live eukaryotic cells

(2015) Iwo König et al.   NATURE METHODS

Liquid-Liquid Phase Separation in Biology

(2014) Anthony A. Hyman et al.   Annual Review of Cell and Developmental Biology

Single-Molecule Studies of Intrinsically Disordered Proteins

(2014) Marco Brucale et al.   CHEMICAL REVIEWS

Introducing Protein Intrinsic Disorder

(2014) Johnny Habchi et al.   CHEMICAL REVIEWS

Classification of Intrinsically Disordered Regions and Proteins

(2014) Robin van der Lee et al.   CHEMICAL REVIEWS

Balanced Protein–Water Interactions Improve Properties of Disordered Proteins and Non-Specific Protein Association

(2014) Robert B. Best et al.   Journal of Chemical Theory and Computation

Slow internal protein dynamics in solution

(2014) R Biehl et al.   JOURNAL OF PHYSICS-CONDENSED MATTER

Internal Nanosecond Dynamics in the Intrinsically Disordered Myelin Basic Protein

(2014) Andreas M. Stadler et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Concerted Dihedral Rotations Give Rise to Internal Friction in Unfolded Proteins

(2014) Ignacia Echeverria et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Temperature-dependent solvation modulates the dimensions of disordered proteins

(2014) R. Wuttke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-molecule spectroscopy reveals chaperone-mediated expansion of substrate protein

(2014) Ruth Kellner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-molecule spectroscopy reveals polymer effects of disordered proteins in crowded environments

(2014) Andrea Soranno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular origins of internal friction effects on protein-folding rates

(2014) David de Sancho et al.   Nature Communications

Combining Experiments and Simulations Using the Maximum Entropy Principle

(2014) Wouter Boomsma et al.   PLoS Computational Biology

Single molecule methods with applications in living cells

(2013) Fredrik Persson et al.   CURRENT OPINION IN BIOTECHNOLOGY

Single-molecule spectroscopy of protein folding dynamics—expanding scope and timescales

(2013) Benjamin Schuler et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Describing intrinsically disordered proteins at atomic resolution by NMR

(2013) Malene Ringkjøbing Jensen et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Exploring the role of internal friction in the dynamics of unfolded proteins using simple polymer models

(2013) Ryan R. Cheng et al.   JOURNAL OF CHEMICAL PHYSICS

Charge regulation in biomolecular solution

(2013) Mikael Lund et al.   QUARTERLY REVIEWS OF BIOPHYSICS

Integrative Structural Biology

(2013) A. B. Ward et al.   SCIENCE

Single-molecule FRET of protein structure and dynamics - a primer

(2013) Benjamin Schuler   JOURNAL OF NANOBIOTECHNOLOGY

Measuring ultrafast protein folding rates from photon-by-photon analysis of single molecule fluorescence trajectories

(2012) Hoi Sung Chung et al.   CHEMICAL PHYSICS

Optimizing Solute–Water van der Waals Interactions To Reproduce Solvation Free Energies

(2012) Paul S. Nerenberg et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Slow Unfolded-State Structuring in Acyl-CoA Binding Protein Folding Revealed by Simulation and Experiment

(2012) Vincent A. Voelz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Peptide Chain Dynamics in Light and Heavy Water: Zooming in on Internal Friction

(2012) Julius C. F. Schulz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Understanding protein aggregation from the view of monomer dynamics

(2012) Lisa J. Lapidus   Molecular BioSystems

Phase transitions in the assembly of multivalent signalling proteins

(2012) Pilong Li et al.   NATURE

Quantifying internal friction in unfolded and intrinsically disordered proteins with single-molecule spectroscopy

(2012) A. Soranno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polymer scaling laws of unfolded and intrinsically disordered proteins quantified with single-molecule spectroscopy

(2012) H. Hofmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Theory of the energy transfer efficiency and fluorescence lifetime distribution in single-molecule FRET

(2012) I. V. Gopich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Localizing internal friction along the reaction coordinate of protein folding by combining ensemble and single-molecule fluorescence spectroscopy

(2012) Alessandro Borgia et al.   Nature Communications

How, when and why proteins collapse: the relation to folding

(2011) Gilad Haran   CURRENT OPINION IN STRUCTURAL BIOLOGY

Solvent Viscosity and Friction in Protein Folding Dynamics

(2010) Stephen J. Hagen   CURRENT PROTEIN & PEPTIDE SCIENCE

Spatiotemporal correlations in denatured proteins: The dependence of fluorescence resonance energy transfer (FRET)-derived protein reconfiguration times on the location of the FRET probes

(2010) Dmitrii E. Makarov   JOURNAL OF CHEMICAL PHYSICS

Protein Simulations with an Optimized Water Model: Cooperative Helix Formation and Temperature-Induced Unfolded State Collapse

(2010) Robert B. Best et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Detection of Structural Dynamics by FRET: A Photon Distribution and Fluorescence Lifetime Analysis of Systems with Multiple States

(2010) Stanislav Kalinin et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Charge interactions can dominate the dimensions of intrinsically disordered proteins

(2010) S. Muller-Spath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-molecule spectroscopy of protein folding in a chaperonin cage

(2010) H. Hofmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kinetics of Contact Formation and End-to-End Distance Distributions of Swollen Disordered Peptides

(2009) Andrea Soranno et al.   BIOPHYSICAL JOURNAL

Linking folding and binding

(2009) Peter E Wright et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Protein dynamics from single-molecule fluorescence intensity correlation functions

(2009) Irina V. Gopich et al.   JOURNAL OF CHEMICAL PHYSICS

How accurate are polymer models in the analysis of Förster resonance energy transfer experiments on proteins?

(2009) Edward P. O’Brien et al.   JOURNAL OF CHEMICAL PHYSICS

Single-molecule spectroscopy of the temperature-induced collapse of unfolded proteins

(2009) D. Nettels et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macromolecular Crowding and Confinement: Biochemical, Biophysical, and Potential Physiological Consequences

(2008) Huan-Xiang Zhou et al.   Annual Review of Biophysics

ABSINTH: A new continuum solvation model for simulations of polypeptides in aqueous solutions

(2008) Andreas Vitalis et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Unfolded Protein and Peptide Dynamics Investigated with Single-Molecule FRET and Correlation Spectroscopy from Picoseconds to Seconds†

(2008) Daniel Nettels et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Collapse transition in proteins

(2008) Guy Ziv et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Measuring internal friction of an ultrafast-folding protein

(2008) T. Cellmer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of denaturants and osmolytes on proteins are accurately predicted by the molecular transfer model

(2008) E. P. O'Brien et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fuzzy complexes: polymorphism and structural disorder in protein–protein interactions

(2007) Peter Tompa et al.   TRENDS IN BIOCHEMICAL SCIENCES