Integrated view of internal friction in unfolded proteins from single-molecule FRET, contact quenching, theory, and simulations

Single-Molecule FRET Spectroscopy and the Polymer Physics of Unfolded and Intrinsically Disordered Proteins

(2016) Benjamin Schuler et al.   Annual Review of Biophysics

Modulation of Folding Internal Friction by Local and Global Barrier Heights

(2016) Wenwei Zheng et al.   Journal of Physical Chemistry Letters

Consistent View of Polypeptide Chain Expansion in Chemical Denaturants from Multiple Experimental Methods

(2016) Alessandro Borgia et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

CHARMM36m: an improved force field for folded and intrinsically disordered proteins

(2016) Jing Huang et al.   NATURE METHODS

Diffusive Dynamics of Contact Formation in Disordered Polypeptides

(2016) Gül H. Zerze et al.   PHYSICAL REVIEW LETTERS

Slow Internal Dynamics and Charge Expansion in the Disordered Protein CGRP: A Comparison with Amylin

(2015) Sara M. Sizemore et al.   BIOPHYSICAL JOURNAL

Unfolding and Folding Internal Friction of β-Hairpins Is Smaller than That of α-Helices

(2015) Julius C. F. Schulz et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Water Dispersion Interactions Strongly Influence Simulated Structural Properties of Disordered Protein States

(2015) Stefano Piana et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Dependence of Internal Friction on Folding Mechanism

(2015) Wenwei Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Single-molecule spectroscopy of protein conformational dynamics in live eukaryotic cells

(2015) Iwo König et al.   NATURE METHODS

Structural origin of slow diffusion in protein folding

(2015) H. S. Chung et al.   SCIENCE

Role of Denatured-State Properties in Chaperonin Action Probed by Single-Molecule Spectroscopy

(2014) Hagen Hofmann et al.   BIOPHYSICAL JOURNAL

Balanced Protein–Water Interactions Improve Properties of Disordered Proteins and Non-Specific Protein Association

(2014) Robert B. Best et al.   Journal of Chemical Theory and Computation

Concerted Dihedral Rotations Give Rise to Internal Friction in Unfolded Proteins

(2014) Ignacia Echeverria et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Temperature-dependent solvation modulates the dimensions of disordered proteins

(2014) R. Wuttke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular origins of internal friction effects on protein-folding rates

(2014) David de Sancho et al.   Nature Communications

Exploring the role of internal friction in the dynamics of unfolded proteins using simple polymer models

(2013) Ryan R. Cheng et al.   JOURNAL OF CHEMICAL PHYSICS

Microfluidic mixer designed for performing single-molecule kinetics with confocal detection on timescales from milliseconds to minutes

(2013) Bengt Wunderlich et al.   Nature Protocols

Optimizing Solute–Water van der Waals Interactions To Reproduce Solvation Free Energies

(2012) Paul S. Nerenberg et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Slow Unfolded-State Structuring in Acyl-CoA Binding Protein Folding Revealed by Simulation and Experiment

(2012) Vincent A. Voelz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Peptide Chain Dynamics in Light and Heavy Water: Zooming in on Internal Friction

(2012) Julius C. F. Schulz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quantifying internal friction in unfolded and intrinsically disordered proteins with single-molecule spectroscopy

(2012) A. Soranno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Localizing internal friction along the reaction coordinate of protein folding by combining ensemble and single-molecule fluorescence spectroscopy

(2012) Alessandro Borgia et al.   Nature Communications

How, when and why proteins collapse: the relation to folding

(2011) Gilad Haran   CURRENT OPINION IN STRUCTURAL BIOLOGY

Solvent Viscosity and Friction in Protein Folding Dynamics

(2010) Stephen J. Hagen   CURRENT PROTEIN & PEPTIDE SCIENCE

Spatiotemporal correlations in denatured proteins: The dependence of fluorescence resonance energy transfer (FRET)-derived protein reconfiguration times on the location of the FRET probes

(2010) Dmitrii E. Makarov   JOURNAL OF CHEMICAL PHYSICS

Unfolded-State Dynamics and Structure of Protein L Characterized by Simulation and Experiment

(2010) Vincent A. Voelz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Experimental evidence for a frustrated energy landscape in a three-helix-bundle protein family

(2010) Beth G. Wensley et al.   NATURE

Extremely slow intramolecular diffusion in unfolded protein L

(2010) S. A. Waldauer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Charge interactions can dominate the dimensions of intrinsically disordered proteins

(2010) S. Muller-Spath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fluorescence Quenching by Photoinduced Electron Transfer: A Reporter for Conformational Dynamics of Macromolecules

(2009) Sören Doose et al.   CHEMPHYSCHEM

Protein dynamics from single-molecule fluorescence intensity correlation functions

(2009) Irina V. Gopich et al.   JOURNAL OF CHEMICAL PHYSICS

Internal Friction and Nonequilibrium Unfolding of Polymeric Globules

(2009) Alfredo Alexander-Katz et al.   PHYSICAL REVIEW LETTERS

Direct observation of ultrafast folding and denatured state dynamics in single protein molecules

(2009) H. Neuweiler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ABSINTH: A new continuum solvation model for simulations of polypeptides in aqueous solutions

(2008) Andreas Vitalis et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Kinetics of Loop Formation in Polymer Chains†

(2008) Ngo Minh Toan et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Measuring internal friction of an ultrafast-folding protein

(2008) T. Cellmer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA