标题
Galectin Targeted Therapy in Oncology: Current Knowledge and Perspectives
作者
关键词
-
出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 19, Issue 1, Pages 210
出版商
MDPI AG
发表日期
2018-01-11
DOI
10.3390/ijms19010210
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Galectin-3 Performance in Histologic and Cytologic Assessment of Thyroid Nodules: A Systematic Review and Meta-Analysis
- (2017) Pierpaolo Trimboli et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The role of T-cell immunoglobulin mucin-3 and its ligand galectin-9 in antitumor immunity and cancer immunotherapy
- (2017) Riyao Yang et al. Science China-Life Sciences
- Galectin-9 as a prognostic and predictive biomarker in bladder urothelial carcinoma
- (2017) Yidong Liu et al. UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
- Stable and high expression of Galectin-8 tightly controls metastatic progression of prostate cancer
- (2017) Lucas Daniel Gentilini et al. Oncotarget
- Combined Anti-VEGF and Anti–CTLA-4 Therapy Elicits Humoral Immunity to Galectin-1 Which Is Associated with Favorable Clinical Outcomes
- (2017) Xinqi Wu et al. Cancer Immunology Research
- Randomised clinical study: GR-MD-02, a galectin-3 inhibitor, vs. placebo in patients having non-alcoholic steatohepatitis with advanced fibrosis
- (2016) S. A. Harrison et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Inhibition of Galectin-1 Sensitizes HRAS-driven Tumor Growth to Rapamycin Treatment
- (2016) JAMES V MICHAEL et al. ANTICANCER RESEARCH
- Roles of Galectin-7 in Cancer
- (2016) Manpreet Kaur et al. Asian Pacific Journal of Cancer Prevention
- Glycosylation-dependent binding of galectin-8 to activated leukocyte cell adhesion molecule (ALCAM/CD166) promotes its surface segregation on breast cancer cells
- (2016) Marisa M. Fernández et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Galectin 3 as a guardian of the tumor microenvironment
- (2016) Peter P. Ruvolo BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Combination of galectin inhibitor GCS-100 and BH3 mimetics eliminates both p53 wild type and p53 null AML cells
- (2016) Peter P. Ruvolo et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Galectin-12 inhibits granulocytic differentiation of human NB4 promyelocytic leukemia cells while promoting lipogenesis
- (2016) Huiting Xue et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Recombinant expression, purification and preliminary biophysical and structural studies of C-terminal carbohydrate recognition domain from human galectin-4
- (2016) Joane K. Rustiguel et al. PROTEIN EXPRESSION AND PURIFICATION
- Dissecting characteristics and dynamics of differentially expressed proteins during multistage carcinogenesis of human colorectal cancer
- (2016) Fang Peng WORLD JOURNAL OF GASTROENTEROLOGY
- Radiation-enhanced therapeutic targeting of galectin-1 enriched malignant stroma in triple negative breast cancer
- (2016) Meenakshi Upreti et al. Oncotarget
- Structural characterisation of human galectin-4 N-terminal carbohydrate recognition domain in complex with glycerol, lactose, 3′-sulfo-lactose, and 2′-fucosyllactose
- (2016) Khuchtumur Bum-Erdene et al. Scientific Reports
- Polymeric Nanomedicine for Tumor-Targeted Combination Therapy to Elicit Synergistic Genotoxicity against Prostate Cancer
- (2015) Qingqing Yang et al. ACS Applied Materials & Interfaces
- The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux
- (2015) Valerie R Wiersma et al. Autophagy
- Galectin expression in cancer diagnosis and prognosis: A systematic review
- (2015) Victor L. Thijssen et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- NMR assignments of the C-terminal domain of human galectin-8
- (2015) Chun-Hao Gerard Liu et al. Biomolecular NMR Assignments
- Novel analogs of antitumor agent calixarene 0118: Synthesis, cytotoxicity, click labeling with 2-[18F]fluoroethylazide, and in vivo evaluation
- (2015) Tilman Läppchen et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Galectin-3 in autoimmunity and autoimmune diseases
- (2015) Felipe L de Oliveira et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Structural characterization of human galectin-4 C-terminal domain: elucidating the molecular basis for recognition of glycosphingolipids, sulfated saccharides and blood group antigens
- (2015) Khuchtumur Bum-Erdene et al. FEBS Journal
- Impact of Exogenous Galectin-9 on Human T Cells
- (2015) Claire Lhuillier et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- G3-C12 Peptide Reverses Galectin-3 from Foe to Friend for Active Targeting Cancer Treatment
- (2015) Wei Sun et al. MOLECULAR PHARMACEUTICS
- Pectin in cancer therapy: A review
- (2015) Wenbo Zhang et al. TRENDS IN FOOD SCIENCE & TECHNOLOGY
- Galectin-9 predicts postoperative recurrence and survival of patients with clear-cell renal cell carcinoma
- (2015) Hangcheng Fu et al. TUMOR BIOLOGY
- Extracellular galectin-3 programs multidrug resistance through Na+/K+-ATPase and P-glycoprotein signaling
- (2015) Yosuke Harazono et al. Oncotarget
- Design of a peptidic inhibitor that targets the dimer interface of a prototypic galectin
- (2015) Maria Claudia Vladoiu et al. Oncotarget
- Galectin-7 is epigenetically-regulated tumor suppressor in gastric cancer
- (2015) Seok-Jun Kim et al. Oncotarget
- Expression and functions of galectin-7 in ovarian cancer
- (2015) Marilyne Labrie et al. Oncotarget
- Synergistic Effects of PectaSol-C Modified Citrus Pectin an Inhibitor of Galectin-3 and Paclitaxel on Apoptosis of Human SKOV-3 Ovarian Cancer Cells
- (2014) Ghamartaj Hossein et al. Asian Pacific Journal of Cancer Prevention
- Changed Expression of E-cadherin and Galectin-9 in Oral Squamous Cell Carcinomas but Lack of Potential as Prognostic Markers
- (2014) Siew Wui Chan et al. Asian Pacific Journal of Cancer Prevention
- A Short Treatment with Galactomannan GM-CT-01 Corrects the Functions of Freshly Isolated Human Tumor-Infiltrating Lymphocytes
- (2014) N. Demotte et al. CLINICAL CANCER RESEARCH
- OTX008, a selective small-molecule inhibitor of galectin-1, downregulates cancer cell proliferation, invasion and tumour angiogenesis
- (2014) Lucile Astorgues-Xerri et al. EUROPEAN JOURNAL OF CANCER
- Galectin-8: A matricellular lectin with key roles in angiogenesis
- (2014) M. F. Troncoso et al. GLYCOBIOLOGY
- Tumor-released Galectin-3, a Soluble Inhibitory Ligand of Human NKp30, Plays an Important Role in Tumor Escape from NK Cell Attack
- (2014) Wei Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Galectin-9 Increases Tim-3+ Dendritic Cells and CD8+ T Cells and Enhances Antitumor Immunity via Galectin-9-Tim-3 Interactions
- (2014) K. Nagahara et al. JOURNAL OF IMMUNOLOGY
- Targeting Prostate Carcinoma by G3-C12 Peptide Conjugated N-(2-Hydroxypropyl)methacrylamide Copolymers
- (2014) Yang Yang et al. MOLECULAR PHARMACEUTICS
- Varied expression and localization of multiple galectins in different cancer cell lines
- (2014) Arun Satelli et al. ONCOLOGY REPORTS
- Linking tumor hypoxia with VEGFR2 signaling and compensatory angiogenesis
- (2014) Diego O Croci et al. OncoImmunology
- Galectin 9 and PINCH, novel immunotherapy targets of renal cell carcinoma: a rationale to find potential tumour antigens and the resulting cytotoxic T lymphocytes induced by the derived peptides
- (2013) Hidenori Kawashima et al. BJU INTERNATIONAL
- Why anti-Bcl-2 clinical trials fail: a solution
- (2013) Y. Harazono et al. CANCER AND METASTASIS REVIEWS
- Pharmacokinetics and antineoplastic activity of galectin-1-targeting OTX008 in combination with sunitinib
- (2013) Massimo Zucchetti et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Human Galectin-3 Selective and High Affinity Inhibitors. Present State and Future Perspectives
- (2013) R. Tellez-Sanz et al. CURRENT MEDICINAL CHEMISTRY
- Regulation of galectin-3-induced apoptosis of Jurkat cells by bothO-glycans andN-glycans on CD45
- (2013) Jing Xue et al. FEBS LETTERS
- Galectin-7 levels predict radiation response in squamous cell carcinoma of the cervix
- (2013) Chiaojung Jillian Tsai et al. GYNECOLOGIC ONCOLOGY
- Polycationic calixarene PTX013, a potent cytotoxic agent against tumors and drug resistant cancer
- (2013) Ruud P. M. Dings et al. INVESTIGATIONAL NEW DRUGS
- Altered galectin-1 serum levels in patients diagnosed with high-grade glioma
- (2013) Tina Verschuere et al. JOURNAL OF NEURO-ONCOLOGY
- Understanding the Specificity of Human Galectin-8C Domain Interactions with Its Glycan Ligands Based on Molecular Dynamics Simulations
- (2013) Sonu Kumar et al. PLoS One
- Therapy of Experimental NASH and Fibrosis with Galectin Inhibitors
- (2013) Peter G. Traber et al. PLoS One
- Galectin-4, a Novel Predictor for Lymph Node Metastasis in Lung Adenocarcinoma
- (2013) Takuo Hayashi et al. PLoS One
- pH-Dependent Recycling of Galectin-3 at the Apical Membrane of Epithelial Cells
- (2013) Tamara Straube et al. TRAFFIC
- Abrogation of galectin-4 expression promotes tumorigenesis in colorectal cancer
- (2013) Seung Won Kim et al. CELLULAR ONCOLOGY
- Galectin-9 Acts as a Prognostic Factor with Antimetastatic Potential in Hepatocellular Carcinoma
- (2012) Zhao-Yang Zhang et al. Asian Pacific Journal of Cancer Prevention
- Galectin-1 inhibits the viability, proliferation, and Th1 cytokine production of nonmalignant T cells in patients with leukemic cutaneous T-cell lymphoma
- (2012) F. Cedeno-Laurent et al. BLOOD
- Galectin-3 binds to CD45 on diffuse large B-cell lymphoma cells to regulate susceptibility to cell death
- (2012) M. C. Clark et al. BLOOD
- Galectin-1 as a potent target for cancer therapy: role in the tumor microenvironment
- (2012) Koichi Ito et al. CANCER AND METASTASIS REVIEWS
- Stromal galectin-1 expression is associated with long-term survival in resectable pancreatic ductal adenocarcinoma
- (2012) Ru Chen et al. CANCER BIOLOGY & THERAPY
- Targeting Galectin-1 Overcomes Breast Cancer-Associated Immunosuppression and Prevents Metastatic Disease
- (2012) T. Dalotto-Moreno et al. CANCER RESEARCH
- A Unique Galectin Signature in Human Prostate Cancer Progression Suggests Galectin-1 as a Key Target for Treatment of Advanced Disease
- (2012) D. J. Laderach et al. CANCER RESEARCH
- Combination effect of PectaSol and Doxorubicin on viability, cell cycle arrest and apoptosis in DU-145 and LNCaP prostate cancer cell lines
- (2012) Najmeh Tehranian et al. CELL BIOLOGY INTERNATIONAL
- Inhibiting galectin-1 reduces murine lung metastasis with increased CD4+ and CD8+ T cells and reduced cancer cell adherence
- (2012) Koichi Ito et al. CLINICAL & EXPERIMENTAL METASTASIS
- Inhibition of metastatic tumor formation in vivo by a bacteriophage display-derived galectin-3 targeting peptide
- (2012) Jessica R. Newton-Northup et al. CLINICAL & EXPERIMENTAL METASTASIS
- Roles of galectin-7 and S100A9 in cervical squamous carcinoma: Clinicopathological andin vitroevidence
- (2012) Hong Zhu et al. INTERNATIONAL JOURNAL OF CANCER
- Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi’s sarcoma
- (2012) Diego O. Croci et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Antitumor Agent Calixarene 0118 Targets Human Galectin-1 as an Allosteric Inhibitor of Carbohydrate Binding
- (2012) Ruud P. M. Dings et al. JOURNAL OF MEDICINAL CHEMISTRY
- Advances and prospects of anginex as a promising anti-angiogenesis and anti-tumor agent
- (2012) Ju Bo Wang et al. PEPTIDES
- Galectin-3 Impairment of MYCN-Dependent Apoptosis-Sensitive Phenotype Is Antagonized by Nutlin-3 in Neuroblastoma Cells
- (2012) Veronica Veschi et al. PLoS One
- Simultaneous determination of serum galectin-3 and -4 levels detects metastases in colorectal cancer patients
- (2012) Hannah Barrow et al. CELLULAR ONCOLOGY
- Thiodigalactoside inhibits murine cancers by concurrently blocking effects of galectin-1 on immune dysregulation, angiogenesis and protection against oxidative stress
- (2011) Koichi Ito et al. ANGIOGENESIS
- Treatment of prostate carcinoma with (Galectin-3)-targeted HPMA copolymer-(G3-C12)-5-Fluorouracil conjugates
- (2011) Yang Yang et al. BIOMATERIALS
- Galectin-3 – A jack-of-all-trades in cancer
- (2011) Anna U. Newlaczyl et al. CANCER LETTERS
- Serum Galectin-2, -4, and -8 Are Greatly Increased in Colon and Breast Cancer Patients and Promote Cancer Cell Adhesion to Blood Vascular Endothelium
- (2011) H. Barrow et al. CLINICAL CANCER RESEARCH
- Association of galectin-3 expression with melanoma progression and prognosis
- (2011) Ewan R. Brown et al. EUROPEAN JOURNAL OF CANCER
- Inhibition mechanism of human galectin-7 by a novel galactose-benzylphosphate inhibitor
- (2011) Geoffrey Masuyer et al. FEBS Journal
- High expression of Galectin-1 in pancreatic stellate cells plays a role in the development and maintenance of an immunosuppressive microenvironment in pancreatic cancer
- (2011) Dong Tang et al. INTERNATIONAL JOURNAL OF CANCER
- The Anti-angiogenic Peptide Anginex Greatly Enhances Galectin-1 Binding Affinity for Glycoproteins
- (2011) Emma Salomonsson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Metabolic Inhibition of Galectin-1-Binding Carbohydrates Accentuates Antitumor Immunity
- (2011) Filiberto Cedeno-Laurent et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Decreased Galectin-8 Is a Strong Marker for Recurrence in Urothelial Carcinoma of the Bladder
- (2011) Mario Wolfgang Kramer et al. UROLOGIA INTERNATIONALIS
- Methodology and Technical Requirements of the Galectin-3 Test for the Preoperative Characterization of Thyroid Nodules
- (2011) Armando Bartolazzi et al. APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY
- Overexpression of Galectin-7, A Myoepithelial Cell Marker, Enhances Spontaneous Metastasis of Breast Cancer Cells
- (2010) Mélanie Demers et al. AMERICAN JOURNAL OF PATHOLOGY
- GCS-100, a novel galectin-3 antagonist, modulates MCL-1, NOXA, and cell cycle to induce myeloma cell death
- (2010) M. J. Streetly et al. BLOOD
- Tumor Cells Secrete Galectin-1 to Enhance Endothelial Cell Activity
- (2010) V. L. Thijssen et al. CANCER RESEARCH
- A Galectin-3 Ligand Corrects the Impaired Function of Human CD4 and CD8 Tumor-Infiltrating Lymphocytes and Favors Tumor Rejection in Mice
- (2010) N. Demotte et al. CANCER RESEARCH
- Hypoxia inducible factor-1 mediates expression of galectin-1: the potential role in migration/invasion of colorectal cancer cells
- (2010) Xu-Yun Zhao et al. CARCINOGENESIS
- MLL-Rearranged B Lymphoblastic Leukemias Selectively Express the Immunoregulatory Carbohydrate-Binding Protein Galectin-1
- (2010) P. Juszczynski et al. CLINICAL CANCER RESEARCH
- Tumor suppressor p16INK4a: Downregulation of galectin-3, an endogenous competitor of the pro-anoikis effector galectin-1, in a pancreatic carcinoma model
- (2010) Hugo Sanchez-Ruderisch et al. FEBS Journal
- PectaSol-C Modified Citrus Pectin Induces Apoptosis and Inhibition of Proliferation in Human and Mouse Androgen-Dependent and- Independent Prostate Cancer Cells
- (2010) Jun Yan et al. INTEGRATIVE CANCER THERAPIES
- Galectin-4 functions as a tumor suppressor of human colorectal cancer
- (2010) Arun Satelli et al. INTERNATIONAL JOURNAL OF CANCER
- Lung Cancer-Derived Galectin-1 Mediates Dendritic Cell Anergy through Inhibitor of DNA Binding 3/IL-10 Signaling Pathway
- (2010) P.-L. Kuo et al. JOURNAL OF IMMUNOLOGY
- Targeting Activating Transcription Factor 3 by Galectin-9 Induces Apoptosis and Overcomes Various Types of Treatment Resistance in Chronic Myelogenous Leukemia
- (2010) J. Kuroda et al. MOLECULAR CANCER RESEARCH
- Unknown
- (2010) Daniela Spano et al. MOLECULAR MEDICINE
- Galectin-9 trafficking regulates apical-basal polarity in Madin–Darby canine kidney epithelial cells
- (2010) Rashmi Mishra et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Calpain activation through galectin-3 inhibition sensitizes prostate cancer cells to cisplatin treatment
- (2010) Y Wang et al. Cell Death & Disease
- Inhibiting Tumor Growth by Targeting Tumor Vasculature with Galectin-1 Antagonist Anginex Conjugated to the Cytotoxic Acylfulvene, 6-Hydroxylpropylacylfulvene
- (2009) Ruud P. M. Dings et al. BIOCONJUGATE CHEMISTRY
- Anti-angiogenesis and anti-tumor effects of AdNT4-anginex
- (2009) Dan Feng Dong et al. CANCER LETTERS
- Intracellular galectin-9 activates inflammatory cytokines in monocytes
- (2009) Ai Matsuura et al. GENES TO CELLS
- The -galactomannan Davanat binds galectin-1 at a site different from the conventional galectin carbohydrate binding domain
- (2009) M. C Miller et al. GLYCOBIOLOGY
- Evaluation of the prognostic significance of serum galectin-3 in American Joint Committee on Cancer stage III and stage IV melanoma patients
- (2009) Pierre Vereecken et al. MELANOMA RESEARCH
- The Galectin Profile of the Endothelium
- (2008) Victor L. Thijssen et al. AMERICAN JOURNAL OF PATHOLOGY
- Citrus pectin affects cytokine production by human peripheral blood mononuclear cells
- (2008) Hertzel Salman et al. BIOMEDICINE & PHARMACOTHERAPY
- Ovarian tumor growth regression using a combination of vascular targeting agents anginex or topomimetic 0118 and the chemotherapeutic irofulven
- (2008) Ruud P.M. Dings et al. CANCER LETTERS
- Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis
- (2008) Masako Seki et al. CLINICAL IMMUNOLOGY
- Dimeric Galectin-8 Induces Phosphatidylserine Exposure in Leukocytes through Polylactosamine Recognition by the C-terminal Domain
- (2008) Sean R. Stowell et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Galectin-3-expression analysis in the surgical selection of follicular thyroid nodules with indeterminate fine-needle aspiration cytology: a prospective multicentre study
- (2008) Armando Bartolazzi et al. LANCET ONCOLOGY
- Evaluation of galectin-8 expression in thyroid tumors
- (2008) S. Savin et al. MEDICAL ONCOLOGY
- Hypoxia and Aggressive Tumor Phenotype: Implications for Therapy and Prognosis
- (2008) P. Vaupel ONCOLOGIST
- Serum Galectin-1 and Galectin-3 Levels in Benign and Malignant Nodular Thyroid Disease
- (2008) Sven Saussez et al. THYROID
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started