Disease-modifying effect of strontium ranelate in a subset of patients from the Phase III knee osteoarthritis study SEKOIA using quantitative MRI: reduction in bone marrow lesions protects against cartilage loss

Strontium ranelate: ready for clinical use as disease-modifying osteoarthritis drug?

(2013) Floris P J G Lafeber et al.   ANNALS OF THE RHEUMATIC DISEASES

Total Knee Replacement as a Knee Osteoarthritis Outcome

(2013) Jean-Pierre Raynauld et al.   Cartilage

Zoledronic acid reduces knee pain and bone marrow lesions over 1 year: a randomised controlled trial

(2012) Laura Louise Laslett et al.   ANNALS OF THE RHEUMATIC DISEASES

Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: results of a double-blind, randomised placebo-controlled trial

(2012) Jean-Yves Reginster et al.   ANNALS OF THE RHEUMATIC DISEASES

Strontium ranelate reduces the progression of experimental dog osteoarthritis by inhibiting the expression of key proteases in cartilage and of IL-1β in the synovium

(2012) Jean-Pierre Pelletier et al.   ANNALS OF THE RHEUMATIC DISEASES

Quantitative MRI measures of cartilage predict knee replacement: a case–control study from the Osteoarthritis Initiative

(2012) Felix Eckstein et al.   ANNALS OF THE RHEUMATIC DISEASES

Assessment of Cartilage Changes Over Time in Knee Osteoarthritis Disease-Modifying Osteoarthritis Drug Trials Using Semiquantitative and Quantitative Methods: Pros and Cons

(2012) Lukas Martin Wildi et al.   ARTHRITIS CARE & RESEARCH

Risk factors predictive of joint replacement in a 2-year multicentre clinical trial in knee osteoarthritis using MRI: results from over 6 years of observation

(2011) J.-P. Raynauld et al.   ANNALS OF THE RHEUMATIC DISEASES

Chondroitin sulphate reduces both cartilage volume loss and bone marrow lesions in knee osteoarthritis patients starting as early as 6 months after initiation of therapy: a randomised, double-blind, placebo-controlled pilot study using MRI

(2011) L. M. Wildi et al.   ANNALS OF THE RHEUMATIC DISEASES

Effects of Hylan G-F 20 supplementation on cartilage preservation detected by magnetic resonance imaging in osteoarthritis of the knee: a two-year single-blind clinical trial

(2011) Yuanyuan Wang et al.   BMC MUSCULOSKELETAL DISORDERS

Strontium ranelate inhibits key factors affecting bone remodeling in human osteoarthritic subchondral bone osteoblasts

(2011) Steeve Kwan Tat et al.   BONE

Efficacy and safety of oral strontium ranelate for the treatment of knee osteoarthritis: rationale and design of randomised, double-blind, placebo-controlled trial

(2011) Cyrus Cooper et al.   CURRENT MEDICAL RESEARCH AND OPINION

Systematic review of the concurrent and predictive validity of MRI biomarkers in OA

(2011) D.J. Hunter et al.   OSTEOARTHRITIS AND CARTILAGE

Strontium Ranelate

(2010) Emma D. Deeks et al.   DRUGS

Bone marrow lesions in people with knee osteoarthritis predict progression of disease and joint replacement: a longitudinal study

(2010) S. K. Tanamas et al.   RHEUMATOLOGY

An Open-Label Pilot Study Evaluating by Magnetic Resonance Imaging the Potential for a Disease-Modifying Effect of Celecoxib Compared to a Modelized Historical Control Cohort in the Treatment of Knee Osteoarthritis

(2010) Jean-Pierre Raynauld et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Osteoblasts play key roles in the mechanisms of action of strontium ranelate

(2009) TC Brennan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Protective effects of licofelone, a 5-lipoxygenase and cyclo-oxygenase inhibitor, versus naproxen on cartilage loss in knee osteoarthritis: a first multicentre clinical trial using quantitative MRI

(2008) J-P Raynauld et al.   ANNALS OF THE RHEUMATIC DISEASES