The Role of Changes in Extracellular Matrix of Cartilage in the Presence of Inflammation on the Pathology of Osteoarthritis

Effects of matrix elasticity and cell density on human mesenchymal stem cells differentiation

(2013) Ruyue Xue et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Subchondral cyst development and MMP-1 expression during progression of osteoarthritis: An immunohistochemical study

(2013) A. Kaspiris et al.   Orthopaedics & Traumatology-Surgery & Research

Osteoarthritis synovial fluid activates pro-inflammatory cytokines in primary human chondrocytes

(2012) Paula Hoff et al.   INTERNATIONAL ORTHOPAEDICS

European Society of Biomechanics S.M. Perren Award 2012: The external mechanical environment can override the influence of local substrate in determining stem cell fate

(2012) Stephen D. Thorpe et al.   JOURNAL OF BIOMECHANICS

Matrilin-3 switches from anti- to pro-anabolic upon integration to the extracellular matrix

(2012) Jean-Baptiste Vincourt et al.   MATRIX BIOLOGY

ECM stiffness primes the TGFβ pathway to promote chondrocyte differentiation

(2012) Jessica L. Allen et al.   MOLECULAR BIOLOGY OF THE CELL

Measurement of matrilin-3 levels in human serum and synovial fluid using a competitive enzyme-linked immunosorbent assay

(2012) J.-B. Vincourt et al.   OSTEOARTHRITIS AND CARTILAGE

Collagen fibril stiffening in osteoarthritic cartilage of human beings revealed by atomic force microscopy

(2012) C.-Y. Wen et al.   OSTEOARTHRITIS AND CARTILAGE

Temporal and spatial migration pattern of the subchondral bone plate in a rabbit osteochondral defect model

(2012) P. Orth et al.   OSTEOARTHRITIS AND CARTILAGE

Intracellular calcium oscillations in articular chondrocytes induced by basic calcium phosphate crystals lead to cartilage degradation

(2012) C. Nguyen et al.   OSTEOARTHRITIS AND CARTILAGE

Transcriptome-wide gene regulation by gentle treadmill walking during the progression of monoiodoacetate-induced arthritis

(2011) Jin Nam et al.   ARTHRITIS AND RHEUMATISM

Proteases involved in cartilage matrix degradation in osteoarthritis

(2011) Linda Troeberg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Tenascin-C induces inflammatory mediators and matrix degradation in osteoarthritic cartilage

(2011) Lisha Patel et al.   BMC MUSCULOSKELETAL DISORDERS

Hyaluronan in part mediates IL-1beta-induced inflammation in mouse chondrocytes by up-regulating CD44 receptors

(2011) Giuseppe M. Campo et al.   GENE

Chondrocyte apoptosis determined by caspase-3 expression varies with fibronectin distribution in equine articular cartilage

(2011) Carla M. THOMAS et al.   International Journal of Rheumatic Diseases

The influence of matrix elasticity on chondrocyte behavior in 3D

(2011) Elena Schuh et al.   Journal of Tissue Engineering and Regenerative Medicine

Sequential Alterations in Catabolic and Anabolic Gene Expression Parallel Pathological Changes during Progression of Monoiodoacetate-Induced Arthritis

(2011) Jin Nam et al.   PLoS One

Catabolic Factors and Osteoarthritis-Conditioned Medium Inhibit Chondrogenesis of Human Mesenchymal Stem Cells

(2011) Genoveva T.H. Heldens et al.   TISSUE ENGINEERING PART A

Development of Methods for Studying the Differentiation of Human Mesenchymal Stem Cells Under Cyclic Compressive Strain

(2011) Efstathios Michalopoulos et al.   TISSUE ENGINEERING PART C-METHODS

Modulation of embryonic mesenchymal progenitor cell differentiation via control over pure mechanical modulus in electrospun nanofibers

(2010) Jin Nam et al.   Acta Biomaterialia

Articular cartilage and subchondral bone in the pathogenesis of osteoarthritis

(2010) Mary B. Goldring et al.   Annals of the New York Academy of Sciences

Circulating levels of IL-6 and TNF-α are associated with knee radiographic osteoarthritis and knee cartilage loss in older adults

(2010) O. Stannus et al.   OSTEOARTHRITIS AND CARTILAGE

Changes in content and synthesis of collagen types and proteoglycans in osteoarthritis of the knee joint and comparison of quantitative analysis with Photoshop-based image analysis

(2009) Andreas Lahm et al.   ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY

Calcification of articular cartilage in human osteoarthritis

(2009) M. Fuerst et al.   ARTHRITIS AND RHEUMATISM

Interleukin-1β and tumor necrosis factor α inhibit chondrogenesis by human mesenchymal stem cells through NF-κB-dependent pathways

(2009) N. Wehling et al.   ARTHRITIS AND RHEUMATISM

Ectopic expression of cyclooxygenase-2-induced dedifferentiation in articular chondrocytes

(2009) Won-Kil Lee et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Rho/ROCK and MEK/ERK activation by transforming growth factor-α induces articular cartilage degradation

(2009) C Thomas G Appleton et al.   LABORATORY INVESTIGATION

Hypoxia reduces the inhibitory effect of IL-1β on chondrogenic differentiation of FCS-free expanded MSC

(2009) T. Felka et al.   OSTEOARTHRITIS AND CARTILAGE

Local cytokine profiles in knee osteoarthritis: elevated synovial fluid interleukin-15 differentiates early from end-stage disease

(2009) C.R. Scanzello et al.   OSTEOARTHRITIS AND CARTILAGE

Collagen Type II Enhances Chondrogenesis in Adipose Tissue–Derived Stem Cells by Affecting Cell Shape

(2009) ZuFu Lu et al.   TISSUE ENGINEERING PART A

Effect of Matrix Elasticity on the Maintenance of the Chondrogenic Phenotype

(2009) Elena Schuh et al.   TISSUE ENGINEERING PART A

Cartilage in normal and osteoarthritis conditions

(2008) Johanne Martel-Pelletier et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Gene expression profiles of human chondrocytes during passaged monolayer cultivation

(2008) Zhen Lin et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Nitric oxide synthase isoforms and NF-κB activity in normal and osteoarthritic human chondrocytes: Regulation by inducible nitric oxide

(2008) S.C. Rosa et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Fragmentation of decorin, biglycan, lumican and keratocan is elevated in degenerate human meniscus, knee and hip articular cartilages compared with age-matched macroscopically normal and control tissues

(2008) James Melrose et al.   ARTHRITIS RESEARCH & THERAPY

In vitro expansion affects the response of chondrocytes to mechanical stimulation

(2007) R.H.J. Das et al.   OSTEOARTHRITIS AND CARTILAGE