Immunologic treatment of Parkinson's disease

Microglia may compensate for dopaminergic neuron loss in experimental Parkinsonism through selective elimination of glutamatergic synapses from the subthalamic nucleus

(2017) Hitomi Aono et al.   GLIA

Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy

(2017) J.A. Obeso et al.   MOVEMENT DISORDERS

T cells from patients with Parkinson’s disease recognize α-synuclein peptides

(2017) David Sulzer et al.   NATURE

Gut microbiota: Implications in Parkinson's disease

(2017) Arun Parashar et al.   PARKINSONISM & RELATED DISORDERS

Diagnosis and Management of Parkinson's Disease

(2017) Joseph Jankovic et al.   SEMINARS IN NEUROLOGY

Anti-α-synuclein immunotherapy reduces α-synuclein propagation in the axon and degeneration in a combined viral vector and transgenic model of synucleinopathy

(2017) Brian Spencer et al.   Acta Neuropathologica Communications

A novel panel of α-synuclein antibodies reveal distinctive staining profiles in synucleinopathies

(2017) Jess-Karan S. Dhillon et al.   PLoS One

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease

(2016) Timothy R. Sampson et al.   CELL

New and emerging medical therapies in Parkinson’s disease

(2016) Mitesh Lotia et al.   EXPERT OPINION ON PHARMACOTHERAPY

Autoimmune atypical parkinsonism — A group of treatable parkinsonism

(2016) Sudheeran Kannoth et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Targeting α-synuclein: Therapeutic options

(2016) Benjamin Dehay et al.   MOVEMENT DISORDERS

First-in-human assessment of PRX002, an anti-α-synuclein monoclonal antibody, in healthy volunteers

(2016) Dale B. Schenk et al.   MOVEMENT DISORDERS

Targeting α-synuclein as a therapeutic strategy for Parkinson’s disease

(2015) Nada B Lawand et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Targeting α-synuclein for treatment of Parkinson's disease: mechanistic and therapeutic considerations

(2015) Benjamin Dehay et al.   LANCET NEUROLOGY

Active immunization against alpha-synuclein ameliorates the degenerative pathology and prevents demyelination in a model of multiple system atrophy

(2015) Markus Mandler et al.   Molecular Neurodegeneration

Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s disease clinical trials

(2014) Markus Mandler et al.   ACTA NEUROPATHOLOGICA

Reducing C-Terminal-Truncated Alpha-Synuclein by Immunotherapy Attenuates Neurodegeneration and Propagation in Parkinson's Disease-Like Models

(2014) D. Games et al.   JOURNAL OF NEUROSCIENCE

A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease

(2012) Peter Holmans et al.   HUMAN MOLECULAR GENETICS

Movement disorders in autoimmune diseases

(2012) José Fidel Baizabal-Carvallo et al.   MOVEMENT DISORDERS

Preclinical Biomarkers of Parkinson Disease

(2011) Yuncheng Wu et al.   ARCHIVES OF NEUROLOGY