First-in-human assessment of PRX002, an anti-α-synuclein monoclonal antibody, in healthy volunteers
出版年份 2016 全文链接
标题
First-in-human assessment of PRX002, an anti-α-synuclein monoclonal antibody, in healthy volunteers
作者
关键词
-
出版物
MOVEMENT DISORDERS
Volume 32, Issue 2, Pages 211-218
出版商
Wiley
发表日期
2016-11-25
DOI
10.1002/mds.26878
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- (2016) Gianluigi Forloni et al. MOVEMENT DISORDERS
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- (2015) Si Liu et al. Scientific Reports
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- (2014) Juan C. Giugni et al. CURRENT OPINION IN NEUROLOGY
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- (2014) D. Games et al. JOURNAL OF NEUROSCIENCE
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- (2014) Stephen Salloway et al. NEW ENGLAND JOURNAL OF MEDICINE
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- (2014) Rachael A. Lawson et al. PARKINSONISM & RELATED DISORDERS
- α-Synuclein Immunotherapy Blocks Uptake and Templated Propagation of Misfolded α-Synuclein and Neurodegeneration
- (2014) Hien T. Tran et al. Cell Reports
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- (2013) Fabienne Sprenger et al. CNS DRUGS
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- (2013) Stacey L. Kowal et al. MOVEMENT DISORDERS
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- (2013) David J Pedrosa et al. Neuropsychiatric Disease and Treatment
- -Synuclein in Parkinson's Disease
- (2013) L. Stefanis Cold Spring Harbor Perspectives in Medicine
- Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice
- (2012) Kelvin C. Luk et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Antibody-Aided Clearance of Extracellular -Synuclein Prevents Cell-to-Cell Aggregate Transmission
- (2012) E.-J. Bae et al. JOURNAL OF NEUROSCIENCE
- α-Synuclein misfolding and Parkinson's disease
- (2011) Leonid Breydo et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Pathways towards an effective immunotherapy for Parkinson’s disease
- (2011) Jessica AL Hutter-Saunders et al. Expert Review of Neurotherapeutics
- α-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: a cohort study
- (2011) Brit Mollenhauer et al. LANCET NEUROLOGY
- Passive Immunization Reduces Behavioral and Neuropathological Deficits in an Alpha-Synuclein Transgenic Model of Lewy Body Disease
- (2011) Eliezer Masliah et al. PLoS One
- DJ-1 and α-synuclein in human cerebrospinal fluid as biomarkers of Parkinson’s disease
- (2010) Zhen Hong et al. BRAIN
- 11C-PiB PET assessment of change in fibrillar amyloid-β load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study
- (2010) Juha O Rinne et al. LANCET NEUROLOGY
- Genetic association between α-synuclein and idiopathic parkinson's disease
- (2008) Denise M. Kay et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
- Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
- (2008) Jia-Yi Li et al. NATURE MEDICINE
- Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease
- (2008) Jeffrey H Kordower et al. NATURE MEDICINE
- Mechanisms of Hybrid Oligomer Formation in the Pathogenesis of Combined Alzheimer's and Parkinson's Diseases
- (2008) Igor F. Tsigelny et al. PLoS One
- Glial reactions in Parkinson's disease
- (2007) Patrick L. McGeer et al. MOVEMENT DISORDERS
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