A novel panel of α-synuclein antibodies reveal distinctive staining profiles in synucleinopathies
出版年份 2017 全文链接
标题
A novel panel of α-synuclein antibodies reveal distinctive staining profiles in synucleinopathies
作者
关键词
Antibodies, Immunohistochemistry techniques, Enzyme-linked immunoassays, Mouse models, Recombinant proteins, Immunoblotting, Monoclonal antibodies, Recombination reactions
出版物
PLoS One
Volume 12, Issue 9, Pages e0184731
出版商
Public Library of Science (PLoS)
发表日期
2017-09-15
DOI
10.1371/journal.pone.0184731
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- T cells from patients with Parkinson’s disease recognize α-synuclein peptides
- (2017) David Sulzer et al. NATURE
- Differential effects of immunotherapy with antibodies targeting α-synuclein oligomers and fibrils in a transgenic model of synucleinopathy
- (2017) Omar El-Agnaf et al. NEUROBIOLOGY OF DISEASE
- Anti-α-synuclein immunotherapy reduces α-synuclein propagation in the axon and degeneration in a combined viral vector and transgenic model of synucleinopathy
- (2017) Brian Spencer et al. Acta Neuropathologica Communications
- Cellular response of human neuroblastoma cells to α-synuclein fibrils, the main constituent of Lewy bodies
- (2016) Laura Pieri et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Like prions: the propagation of aggregated tau and α-synuclein in neurodegeneration
- (2016) Michel Goedert et al. BRAIN
- Cellular Uptake of α-Synuclein Oligomer-Selective Antibodies is Enhanced by the Extracellular Presence of α-Synuclein and Mediated via Fcγ Receptors
- (2016) Gabriel Gustafsson et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Proteolysis of α-synuclein fibrils in the lysosomal pathway limits induction of inclusion pathology
- (2016) Amanda N. Sacino et al. JOURNAL OF NEUROCHEMISTRY
- Robust Central Nervous System Pathology in Transgenic Mice following Peripheral Injection of α-Synuclein Fibrils
- (2016) Jacob I. Ayers et al. JOURNAL OF VIROLOGY
- First-in-human assessment of PRX002, an anti-α-synuclein monoclonal antibody, in healthy volunteers
- (2016) Dale B. Schenk et al. MOVEMENT DISORDERS
- Propagation of alpha-synuclein pathology: hypotheses, discoveries, and yet unresolved questions from experimental and human brain studies
- (2015) Toshiki Uchihara et al. ACTA NEUROPATHOLOGICA
- Studies of lipopolysaccharide effects on the induction of α-synuclein pathology by exogenous fibrils in transgenic mice
- (2015) Nicola J. Rutherford et al. Molecular Neurodegeneration
- Active immunization against alpha-synuclein ameliorates the degenerative pathology and prevents demyelination in a model of multiple system atrophy
- (2015) Markus Mandler et al. Molecular Neurodegeneration
- Active immunization therapies for Parkinson's disease and multiple system atrophy
- (2015) Achim Schneeberger et al. MOVEMENT DISORDERS
- Anti-Human α-Synuclein N-Terminal Peptide Antibody Protects against Dopaminergic Cell Death and Ameliorates Behavioral Deficits in an AAV-α-Synuclein Rat Model of Parkinson’s Disease
- (2015) Md Shahaduzzaman et al. PLoS One
- Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s disease clinical trials
- (2014) Markus Mandler et al. ACTA NEUROPATHOLOGICA
- Amyloid-ß-directed immunotherapy for Alzheimer's disease
- (2014) L. Lannfelt et al. JOURNAL OF INTERNAL MEDICINE
- Reducing C-Terminal-Truncated Alpha-Synuclein by Immunotherapy Attenuates Neurodegeneration and Propagation in Parkinson's Disease-Like Models
- (2014) D. Games et al. JOURNAL OF NEUROSCIENCE
- Cell-to-cell transmission of pathogenic proteins in neurodegenerative diseases
- (2014) Jing L Guo et al. NATURE MEDICINE
- Immunotherapy targeting α-synuclein protofibrils reduced pathology in (Thy-1)-h[A30P] α-synuclein mice
- (2014) Veronica Lindström et al. NEUROBIOLOGY OF DISEASE
- Intramuscular injection of -synuclein induces CNS -synuclein pathology and a rapid-onset motor phenotype in transgenic mice
- (2014) A. N. Sacino et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- α-Synuclein Immunotherapy Blocks Uptake and Templated Propagation of Misfolded α-Synuclein and Neurodegeneration
- (2014) Hien T. Tran et al. Cell Reports
- α-Synuclein Vaccination Prevents the Accumulation of Parkinson Disease-Like Pathologic Inclusions in Striatum in Association With Regulatory T Cell Recruitment in a Rat Model
- (2013) Vanesa Sanchez-Guajardo et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- MHCII Is Required for -Synuclein-Induced Activation of Microglia, CD4 T Cell Proliferation, and Dopaminergic Neurodegeneration
- (2013) A. S. Harms et al. JOURNAL OF NEUROSCIENCE
- Divergent α-synuclein solubility and aggregation properties in G2019S LRRK2 Parkinson's disease brains with Lewy Body pathology compared to idiopathic cases
- (2013) Adamantios Mamais et al. NEUROBIOLOGY OF DISEASE
- Immunotherapy for neurodegenerative diseases: Focus on α-synucleinopathies
- (2013) Elvira Valera et al. PHARMACOLOGY & THERAPEUTICS
- Transmission of multiple system atrophy prions to transgenic mice
- (2013) J. C. Watts et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural and functional characterization of two alpha-synuclein strains
- (2013) Luc Bousset et al. Nature Communications
- The Amyloid State of Proteins in Human Diseases
- (2012) David Eisenberg et al. CELL
- Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice
- (2012) Kelvin C. Luk et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Antibody-Aided Clearance of Extracellular -Synuclein Prevents Cell-to-Cell Aggregate Transmission
- (2012) E.-J. Bae et al. JOURNAL OF NEUROSCIENCE
- 100 years of Lewy pathology
- (2012) Michel Goedert et al. Nature Reviews Neurology
- E46K Human α-Synuclein Transgenic Mice Develop Lewy-like and Tau Pathology Associated with Age-dependent, Detrimental Motor Impairment
- (2011) Kristel L. Emmer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Vaccination for Parkinson's disease
- (2011) A. Schneeberger et al. PARKINSONISM & RELATED DISORDERS
- Passive Immunization Reduces Behavioral and Neuropathological Deficits in an Alpha-Synuclein Transgenic Model of Lewy Body Disease
- (2011) Eliezer Masliah et al. PLoS One
- The propagation of prion-like protein inclusions in neurodegenerative diseases
- (2010) Michel Goedert et al. TRENDS IN NEUROSCIENCES
- Characterization of antibodies that selectively detect α-synuclein in pathological inclusions
- (2008) Elisa A. Waxman et al. ACTA NEUROPATHOLOGICA
- Molecular mechanisms of α-synuclein neurodegeneration
- (2008) Elisa A. Waxman et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now