Combination therapy of lovastatin and AMP-activated protein kinase activator improves mitochondrial and peroxisomal functions and clinical disease in experimental autoimmune encephalomyelitis model
出版年份 2018 全文链接
标题
Combination therapy of lovastatin and AMP-activated protein kinase activator improves mitochondrial and peroxisomal functions and clinical disease in experimental autoimmune encephalomyelitis model
作者
关键词
-
出版物
IMMUNOLOGY
Volume 154, Issue 3, Pages 434-451
出版商
Wiley
发表日期
2018-01-13
DOI
10.1111/imm.12893
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Protective Role of S-Nitrosoglutathione (GSNO) Against Cognitive Impairment in Rat Model of Chronic Cerebral Hypoperfusion
- (2018) Je-Seong Won et al. JOURNAL OF ALZHEIMERS DISEASE
- Evidence for possible role of melatonin in reducing oxidative stress in multiple sclerosis through its effect on SIRT1 and antioxidant enzymes
- (2016) Solaleh Emamgholipour et al. LIFE SCIENCES
- PPARs and Mitochondrial Metabolism: From NAFLD to HCC
- (2016) Tommaso Mello et al. PPAR Research
- Statin Treatment in Multiple Sclerosis: A Systematic Review and Meta-Analysis
- (2015) Gorm Pihl-Jensen et al. CNS DRUGS
- ABCD1 deletion-induced mitochondrial dysfunction is corrected by SAHA: implication for adrenoleukodystrophy
- (2015) Mauhamad Baarine et al. JOURNAL OF NEUROCHEMISTRY
- Update on treatments in multiple sclerosis
- (2015) Laure Michel et al. PRESSE MEDICALE
- Peroxisomes: A Nexus for Lipid Metabolism and Cellular Signaling
- (2014) Irfan J. Lodhi et al. Cell Metabolism
- Simvastatin attenuates TNF-α-induced apoptosis in endothelial progenitor cells via the upregulation of SIRT1
- (2014) GANG DU et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Effect of high-dose simvastatin on brain atrophy and disability in secondary progressive multiple sclerosis (MS-STAT): a randomised, placebo-controlled, phase 2 trial
- (2014) Jeremy Chataway et al. LANCET
- AMP-Activated Protein Kinase Signaling Protects Oligodendrocytes that Restore Central Nervous System Functions in an Experimental Autoimmune Encephalomyelitis Model
- (2013) Ajaib S. Paintlia et al. AMERICAN JOURNAL OF PATHOLOGY
- Mitochondrial dysfunction and oxidative damage cooperatively fuel axonal degeneration in X-linked adrenoleukodystrophy
- (2013) Stéphane Fourcade et al. BIOCHIMIE
- Role of endogenous psychosine accumulation in oligodendrocyte differentiation and survival: Implication for Krabbe disease
- (2013) Je-Seong Won et al. BRAIN RESEARCH
- Modulation of Rho-Rock signaling pathway protects oligodendrocytes against cytokine toxicity via PPAR-α-dependent mechanism
- (2013) Ajaib S. Paintlia et al. GLIA
- Fish-oil emulsion (omega-3 polyunsaturated fatty acids) attenuates acute lung injury induced by intestinal ischemia–reperfusion through Adenosine 5′-monophosphate-activated protein kinase–sirtuin1 pathway
- (2013) Huirong Jing et al. JOURNAL OF SURGICAL RESEARCH
- Peroxisome Proliferator-Activated Receptor Targets for the Treatment of Metabolic Diseases
- (2013) Francisco A. Monsalve et al. MEDIATORS OF INFLAMMATION
- Reductions in neuronal peroxisomes in multiple sclerosis grey matter
- (2013) Elizabeth Gray et al. Multiple Sclerosis Journal
- Pharmacological approaches to restore mitochondrial function
- (2013) Pénélope A. Andreux et al. NATURE REVIEWS DRUG DISCOVERY
- Mitochondrial dysfunction contributes to neurodegeneration in multiple sclerosis
- (2013) Maarten E. Witte et al. TRENDS IN MOLECULAR MEDICINE
- Interference with RhoA–ROCK Signaling Mechanism in Autoreactive CD4+ T Cells Enhances the Bioavailability of 1,25-Dihydroxyvitamin D3 in Experimental Autoimmune Encephalomyelitis
- (2012) Ajaib S. Paintlia et al. AMERICAN JOURNAL OF PATHOLOGY
- Antiaging Effects of Simvastatin on Vascular Endothelial Cells
- (2012) Junping Lei et al. CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS
- PGC1 and mitochondrial metabolism - emerging concepts and relevance in ageing and neurodegenerative disorders
- (2012) S. Austin et al. JOURNAL OF CELL SCIENCE
- Mitochondrial dysfunction and oxidative stress in Parkinson's disease and monogenic parkinsonism
- (2012) David N. Hauser et al. NEUROBIOLOGY OF DISEASE
- Role of peroxisomes in ROS/RNS-metabolism: Implications for human disease
- (2011) Marc Fransen et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Increased mitochondrial content in remyelinated axons: implications for multiple sclerosis
- (2011) Jessica L. Zambonin et al. BRAIN
- A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis
- (2011) Ivana Nikić et al. NATURE MEDICINE
- Induction of Endothelial Nitric Oxide Synthase, SIRT1, and Catalase by Statins Inhibits Endothelial Senescence Through the Akt Pathway
- (2010) Hidetaka Ota et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network
- (2010) Richard C. Scarpulla BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Regulation of mitochondrial biogenesis
- (2010) François R. Jornayvaz et al. Essays in Biochemistry
- Myelin lesions associated with lysosomal and peroxisomal disorders
- (2010) Phyllis L Faust et al. Expert Review of Neurotherapeutics
- Activation of PPAR-γ and PTEN cascade participates in lovastatin-mediated accelerated differentiation of oligodendrocyte progenitor cells
- (2010) Ajaib S. Paintlia et al. GLIA
- Synergistic activity of interleukin-17 and tumor necrosis factor-α enhances oxidative stress-mediated oligodendrocyte apoptosis
- (2010) Manjeet K. Paintlia et al. JOURNAL OF NEUROCHEMISTRY
- Loss of AMPK exacerbates experimental autoimmune encephalomyelitis disease severity
- (2009) Narender Nath et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Mitochondrial changes within axons in multiple sclerosis
- (2009) D. J. Mahad et al. BRAIN
- Biogenesis of peroxisomes and mitochondria: linked by division
- (2009) Hannah K. Delille et al. HISTOCHEMISTRY AND CELL BIOLOGY
- Metformin Attenuated the Autoimmune Disease of the Central Nervous System in Animal Models of Multiple Sclerosis
- (2009) N. Nath et al. JOURNAL OF IMMUNOLOGY
- AMPK in Health and Disease
- (2009) Gregory R. Steinberg et al. PHYSIOLOGICAL REVIEWS
- Statins inhibit Rho kinase activity in patients with atherosclerosis
- (2008) Anju Nohria et al. ATHEROSCLEROSIS
- Mitochondrial defects in acute multiple sclerosis lesions
- (2008) Don Mahad et al. BRAIN
- Shaping mitochondria: The complex posttranslational regulation of the mitochondrial fission protein DRP1
- (2008) Ansgar Santel et al. IUBMB LIFE
- Modulation of peroxisome proliferator-activated receptor-α activity by N-acetyl cysteine attenuates inhibition of oligodendrocyte development in lipopolysaccharide stimulated mixed glial cultures
- (2008) Manjeet K. Paintlia et al. JOURNAL OF NEUROCHEMISTRY
- Inhibition of Rho Family Functions by Lovastatin Promotes Myelin Repair in Ameliorating Experimental Autoimmune Encephalomyelitis
- (2008) A. S. Paintlia et al. MOLECULAR PHARMACOLOGY
- Review: Mitochondria and disease progression in multiple sclerosis
- (2008) D. Mahad et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started