标题
Notch signaling as a therapeutic target for acute lymphoblastic leukemia
作者
关键词
-
出版物
EXPERT OPINION ON THERAPEUTIC TARGETS
Volume 22, Issue 4, Pages 331-342
出版商
Informa UK Limited
发表日期
2018-03-12
DOI
10.1080/14728222.2018.1451840
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- The role of CXCL12 in tumor microenvironment
- (2018) Wenfang Meng et al. GENE
- The mazy case of Notch and immunoregulatory cells
- (2017) Paola Grazioli et al. JOURNAL OF LEUKOCYTE BIOLOGY
- CXCR4 Ligands: The Next Big Hit?
- (2017) Annemiek M.E. Walenkamp et al. JOURNAL OF NUCLEAR MEDICINE
- The common oncogenomic program of NOTCH1 and NOTCH3 signaling in T-cell acute lymphoblastic leukemia
- (2017) Sung Hee Choi et al. PLoS One
- Synergistic antileukemic therapies inNOTCH1-induced T-ALL
- (2017) Marta Sanchez-Martin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of a novel chalcone derivative that inhibits Notch signaling in T-cell acute lymphoblastic leukemia
- (2017) Mattia Mori et al. Scientific Reports
- Advances in understanding the acute lymphoblastic leukemia bone marrow microenvironment: From biology to therapeutic targeting
- (2016) Francesca Chiarini et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- High selective pressure for Notch1 mutations that induce Myc in T-cell acute lymphoblastic leukemia
- (2016) M. Y. Chiang et al. BLOOD
- Effects of pharmacological and genetic disruption of CXCR4 chemokine receptor function in B-cell acute lymphoblastic leukaemia
- (2016) Shubhchintan Randhawa et al. BRITISH JOURNAL OF HAEMATOLOGY
- Aberrant Notch Signaling in the Bone Marrow Microenvironment of Acute Lymphoid Leukemia Suppresses Osteoblast-Mediated Support of Hematopoietic Niche Function
- (2016) Weihuan Wang et al. CANCER RESEARCH
- PIN1 in breast development and cancer: a clinical perspective
- (2016) Alessandra Rustighi et al. CELL DEATH AND DIFFERENTIATION
- Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL progression
- (2016) G Franciosa et al. ONCOGENE
- Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies
- (2016) P Bernasconi-Elias et al. ONCOGENE
- MicroRNA-101 regulates T-cell acute lymphoblastic leukemia progression and chemotherapeutic sensitivity by targeting Notch1
- (2016) Lu Qian et al. ONCOLOGY REPORTS
- The clerodane diterpene casearin J induces apoptosis of T-ALL cells through SERCA inhibition, oxidative stress, and interference with Notch1 signaling
- (2016) C De Ford et al. Cell Death & Disease
- CXCR4 Is Required for Leukemia-Initiating Cell Activity in T Cell Acute Lymphoblastic Leukemia
- (2015) Diana Passaro et al. CANCER CELL
- CXCL12-Producing Vascular Endothelial Niches Control Acute T Cell Leukemia Maintenance
- (2015) Lauren A. Pitt et al. CANCER CELL
- Targeting Notch Signaling with a Notch2/Notch3 Antagonist (Tarextumab) Inhibits Tumor Growth and Decreases Tumor-Initiating Cell Frequency
- (2015) W.-C. Yen et al. CLINICAL CANCER RESEARCH
- Molecular Pathways: Targeting the CXCR4-CXCL12 Axis--Untapped Potential in the Tumor Microenvironment
- (2015) S. Scala CLINICAL CANCER RESEARCH
- Effect of rMnSOD on Survival Signaling in Pediatric High Risk T-Cell Acute Lymphoblastic Leukaemia
- (2015) A. Pica et al. JOURNAL OF CELLULAR PHYSIOLOGY
- The Role of Epigenetic Mechanisms in Notch Signaling During Development
- (2015) Ralf Schwanbeck JOURNAL OF CELLULAR PHYSIOLOGY
- Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer
- (2015) Shuo Wei et al. NATURE MEDICINE
- Targeting Notch, Hedgehog and Wnt pathways in cancer stem cells: clinical update
- (2015) Naoko Takebe et al. Nature Reviews Clinical Oncology
- A Phase 1 study of the novel gamma-secretase inhibitor PF-03084014 in patients with T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma
- (2015) C Papayannidis et al. Blood Cancer Journal
- The epigenetic factor BORIS/CTCFL regulates the NOTCH3 gene expression in cancer cells
- (2014) Michele Zampieri et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- A Jagged Road to Lymphoma Aggressiveness
- (2014) Vedran Radojcic et al. CANCER CELL
- DLL4 regulates NOTCH signaling and growth of T acute lymphoblastic leukemia cells in NOD/SCID mice
- (2014) Sonia Minuzzo et al. CARCINOGENESIS
- The Molecular Basis of Notch Signaling Regulation: A Complex Simplicity
- (2014) R. Palermo et al. CURRENT MOLECULAR MEDICINE
- Phenothiazines induce PP2A-mediated apoptosis in T cell acute lymphoblastic leukemia
- (2014) Alejandro Gutierrez et al. JOURNAL OF CLINICAL INVESTIGATION
- A microRNA-mediated regulatory loop modulates NOTCH and MYC oncogenic signals in B- and T-cell malignancies
- (2014) M Ortega et al. LEUKEMIA
- Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemia
- (2014) V Kumar et al. LEUKEMIA
- Combination of Imatinib with CXCR4 Antagonist BKT140 Overcomes the Protective Effect of Stroma and Targets CML In Vitro and In Vivo
- (2014) K. Beider et al. MOLECULAR CANCER THERAPEUTICS
- Cell competition is a tumour suppressor mechanism in the thymus
- (2014) Vera C. Martins et al. NATURE
- Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia
- (2014) Panagiotis Ntziachristos et al. NATURE
- An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia
- (2014) Birgit Knoechel et al. NATURE GENETICS
- Notch3/Jagged1 Circuitry Reinforces Notch Signaling and Sustains T-ALL
- (2014) Maria Pelullo et al. NEOPLASIA
- DIAGNOSIS AND SUBCLASSIFICATION OF ACUTE LYMPHOBLASTIC LEUKEMIA
- (2014) Sabina Chiaretti et al. Mediterranean Journal of Hematology and Infectious Diseases
- Complementary Genomic Screens Identify SERCA as a Therapeutic Target in NOTCH1 Mutated Cancer
- (2013) Giovanni Roti et al. CANCER CELL
- Prolyl-isomerase Pin1 controls normal and cancer stem cells of the breast
- (2013) Alessandra Rustighi et al. EMBO Molecular Medicine
- Relapsed childhood acute lymphoblastic leukaemia
- (2013) Deepa Bhojwani et al. LANCET ONCOLOGY
- Therapeutic antibody targeting of Notch1 in T-acute lymphoblastic leukemia xenografts
- (2013) V Agnusdei et al. LEUKEMIA
- Notch inhibitors for cancer treatment
- (2013) Ingrid Espinoza et al. PHARMACOLOGY & THERAPEUTICS
- Targeting Notch signaling pathway in cancer: Clinical development advances and challenges
- (2013) Naoko Takebe et al. PHARMACOLOGY & THERAPEUTICS
- Epigenetic Inactivation of Notch-Hes Pathway in Human B-Cell Acute Lymphoblastic Leukemia
- (2013) Shao-Qing Kuang et al. PLoS One
- NOTCH1-RBPJ complexes drive target gene expression through dynamic interactions with superenhancers
- (2013) H. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A review on CXCR4/CXCL12 axis in oncology: No place to hide
- (2012) Urszula M. Domanska et al. EUROPEAN JOURNAL OF CANCER
- HIG1, a novel regulator of mitochondrial γ-secretase, maintains normal mitochondrial function
- (2012) Hiroki Hayashi et al. FASEB JOURNAL
- PI3K/mTOR inhibition upregulates NOTCH-MYC signalling leading to an impaired cytotoxic response
- (2012) C Shepherd et al. LEUKEMIA
- Preclinical Analysis of the -Secretase Inhibitor PF-03084014 in Combination with Glucocorticoids in T-cell Acute Lymphoblastic Leukemia
- (2012) J. B. Samon et al. MOLECULAR CANCER THERAPEUTICS
- NOTCH1 Nuclear Interactome Reveals Key Regulators of Its Transcriptional Activity and Oncogenic Function
- (2012) Ahmad Yatim et al. MOLECULAR CELL
- Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia
- (2012) Panagiotis Ntziachristos et al. NATURE MEDICINE
- Modulating the Strength and Threshold of NOTCH Oncogenic Signals by mir-181a-1/b-1
- (2012) Rita Fragoso et al. PLoS Genetics
- Notch1 inhibition targets the leukemia-initiating cells in a Tal1/Lmo2 mouse model of T-ALL
- (2011) J. Tatarek et al. BLOOD
- Notch-3 and Notch-4 signaling rescue from apoptosis human B-ALL cells in contact with human bone marrow-derived mesenchymal stromal cells
- (2011) A. H. Nwabo Kamdje et al. BLOOD
- Modulation of microRNA expression in human T-cell development: targeting of NOTCH3 by miR-150
- (2011) M. Ghisi et al. BLOOD
- Notch3 and Canonical NF- B Signaling Pathways Cooperatively Regulate Foxp3 Transcription
- (2011) A. Barbarulo et al. JOURNAL OF IMMUNOLOGY
- Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase
- (2011) Virginia Guarani et al. NATURE
- Challenging issues in pediatric oncology
- (2011) Ching-Hon Pui et al. Nature Reviews Clinical Oncology
- Acetylation controls Notch3 stability and function in T-cell leukemia
- (2011) R Palermo et al. ONCOGENE
- Molecular pathogenesis and targeted therapies for NOTCH1-induced T-cell acute lymphoblastic leukemia
- (2010) Maddalena Paganin et al. BLOOD REVIEWS
- A NADPH Oxidase–Dependent Redox Signaling Pathway Mediates the Selective Radiosensitization Effect of Parthenolide in Prostate Cancer Cells
- (2010) Yulan Sun et al. CANCER RESEARCH
- Therapeutic antibody targeting of individual Notch receptors
- (2010) Yan Wu et al. NATURE
- Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia
- (2010) Konstantinos J. Mavrakis et al. NATURE CELL BIOLOGY
- Characterization of Notch1 Antibodies That Inhibit Signaling of Both Normal and Mutated Notch1 Receptors
- (2010) Miguel Aste-Amézaga et al. PLoS One
- Targeting the Notch1 and mTOR pathways in a mouse T-ALL model
- (2009) K. Cullion et al. BLOOD
- Expression of CD133 on leukemia-initiating cells in childhood ALL
- (2009) C. V. Cox et al. BLOOD
- Inhibition of NOTCH Signaling by Gamma Secretase Inhibitor Engages the RB Pathway and Elicits Cell Cycle Exit in T-Cell Acute Lymphoblastic Leukemia Cells
- (2009) S. S. Rao et al. CANCER RESEARCH
- Peptidyl-Prolyl Isomerase Pin1 Markedly Enhances the Oncogenic Activity of the Rel Proteins in the Nuclear Factor- B Family
- (2009) G. Fan et al. CANCER RESEARCH
- Direct inhibition of the NOTCH transcription factor complex
- (2009) Raymond E. Moellering et al. NATURE
- Differential subcellular localization regulates c-Cbl E3 ligase activity upon Notch3 protein in T-cell leukemia
- (2009) S Checquolo et al. ONCOGENE
- KLF4 gene expression is inhibited by the notch signaling pathway that controls goblet cell differentiation in mouse gastrointestinal tract
- (2008) Hai Zheng et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Constitutively activated Notch signaling is involved in survival and apoptosis resistance of B-CLL cells
- (2008) E. Rosati et al. BLOOD
- NOTCH1 extracellular juxtamembrane expansion mutations in T-ALL
- (2008) M. L. Sulis et al. BLOOD
- Modulation of Notch Signaling by Antibodies Specific for the Extracellular Negative Regulatory Region of NOTCH3
- (2008) Kang Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- γ-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia
- (2008) Pedro J Real et al. NATURE MEDICINE
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