Absence of cannabinoid 1 receptor in beta cells protects against high-fat/high-sugar diet-induced beta cell dysfunction and inflammation in murine islets

Effects of systemic multiexon skipping with peptide-conjugated morpholinos in the heart of a dog model of Duchenne muscular dystrophy

(2017) Yusuke Echigoya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The cannabinoid ligand LH-21 reduces anxiety and improves glucose handling in diet-induced obese pre-diabetic mice

(2017) Silvana Y. Romero-Zerbo et al.   Scientific Reports

Calorie restriction as an intervention in ageing

(2016) Guillermo López-Lluch et al.   JOURNAL OF PHYSIOLOGY-LONDON

Blockade of cannabinoid 1 receptor improves GLP-1R mediated insulin secretion in mice

(2016) Isabel González-Mariscal et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

A cannabinoid link between mitochondria and memory

(2016) Etienne Hebert-Chatelain et al.   NATURE

Cannabinoid CB1 Receptors Are Localized in Striated Muscle Mitochondria and Regulate Mitochondrial Respiration

(2016) Juan Mendizabal-Zubiaga et al.   Frontiers in Physiology

Human CB1 Receptor Isoforms, present in Hepatocytes and β-cells, are Involved in Regulating Metabolism

(2016) Isabel González-Mariscal et al.   Scientific Reports

The Regulation and Function of Lactate Dehydrogenase A: Therapeutic Potential in Brain Tumor

(2015) Cara J. Valvona et al.   BRAIN PATHOLOGY

Human β-Cell Proliferation and Intracellular Signaling: Part 3

(2015) Andrew F. Stewart et al.   DIABETES

Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture

(2015) Katarzyna Malenczyk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endocannabinoid signaling at the periphery: 50 years after THC

(2015) Mauro Maccarrone et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Mitochondrial CB1 receptor is involved in ACEA-induced protective effects on neurons and mitochondrial functions

(2015) Lei Ma et al.   Scientific Reports

Toll-like receptors and NLRP3 as central regulators of pancreatic islet inflammation in type 2 diabetes

(2014) Clara Westwell-Roper et al.   IMMUNOLOGY AND CELL BIOLOGY

Exposure to excess insulin (glargine) induces type 2 diabetes mellitus in mice fed on a chow diet

(2014) Xuefeng Yang et al.   JOURNAL OF ENDOCRINOLOGY

Targeting the pancreatic β-cell to treat diabetes

(2014) Amedeo Vetere et al.   NATURE REVIEWS DRUG DISCOVERY

RETRACTED: Betatrophin: A Hormone that Controls Pancreatic β Cell Proliferation

(2013) Peng Yi et al.   CELL

A Mouse Model of Human Hyperinsulinism Produced by the E1506K Mutation in the Sulphonylurea Receptor SUR1

(2013) K. Shimomura et al.   DIABETES

The cannabinoid receptor 1 and its role in influencing peripheral metabolism

(2013) L. O'Keefe et al.   DIABETES OBESITY & METABOLISM

Hepatic cannabinoid-1 receptors mediate diet-induced insulin resistance by increasingde novosynthesis of long-chain ceramides

(2013) Resat Cinar et al.   HEPATOLOGY

Thioredoxin-mediated Denitrosylation Regulates Cytokine-induced Nuclear Factor κB (NF-κB) Activation

(2013) Zachary T. Kelleher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CB1Cannabinoid Receptors Couple to Focal Adhesion Kinase to Control Insulin Release

(2013) Katarzyna Malenczyk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes

(2013) Tony Jourdan et al.   NATURE MEDICINE

Pancreas++: Automated Quantification of Pancreatic Islet Cells in Microscopy Images

(2013) Hongyu Chen et al.   Frontiers in Physiology

Blockade of β-cell KATP channels by the endocannabinoid, 2-arachidonoylglycerol

(2012) Charles E. Spivak et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Peripheral Cannabinoid-1 Receptor Inverse Agonism Reduces Obesity by Reversing Leptin Resistance

(2012) Joseph Tam et al.   Cell Metabolism

Signal Transduction via Cannabinoid Receptors

(2012) George Dalton et al.   CNS & Neurological Disorders-Drug Targets

Cannabinoids Inhibit Insulin Receptor Signaling in Pancreatic  -Cells

(2011) W. Kim et al.   DIABETES

A role for the putative cannabinoid receptor GPR55 in the islets of Langerhans

(2011) Silvana Y Romero-Zerbo et al.   JOURNAL OF ENDOCRINOLOGY

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

(2011) Bolormaa Vandanmagsar et al.   NATURE MEDICINE

Role of JNK activation in pancreatic β-cell death by streptozotocin

(2010) Hwanju Cheon et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The endocannabinoid system, eating behavior and energy homeostasis: The end or a new beginning?

(2010) F.J. Bermudez-Silva et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

The role of the pancreatic endocannabinoid system in glucose metabolism

(2009) Francisco J. Bermúdez-Silva et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

(2009) Rongbin Zhou et al.   NATURE IMMUNOLOGY

The endocannabinoid system: Role in glucose and energy metabolism

(2009) Ruben Nogueiras et al.   PHARMACOLOGICAL RESEARCH

Mitochondrial Reactive Oxygen Species Are Obligatory Signals for Glucose-Induced Insulin Secretion

(2008) C. Leloup et al.   DIABETES

Dysregulation of the Endocannabinoid System in Obesity

(2008) S. Engeli   JOURNAL OF NEUROENDOCRINOLOGY

The Role of Incretins in Glucose Homeostasis and Diabetes Treatment

(2008) W. Kim et al.   PHARMACOLOGICAL REVIEWS

Cannabinoids inhibit insulin secretion and cytosolic Ca2+ oscillation in islet β-cells via CB1 receptors

(2007) Masanori Nakata et al.   REGULATORY PEPTIDES