The cannabinoid receptor 1 and its role in influencing peripheral metabolism

Activation of the sympathetic nervous system mediates hypophagic and anxiety-like effects of CB1 receptor blockade

(2013) L. Bellocchio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

JD-5006 and JD-5037: Peripherally restricted (PR) cannabinoid-1 receptor blockers related to SLV-319 (Ibipinabant) as metabolic disorder therapeutics devoid of CNS liabilities

(2012) Robert J. Chorvat et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Dietary linoleic acid elevates endogenous 2-arachidonoylglycerol and anandamide in Atlantic salmon (Salmo salar L.) and mice, and induces weight gain and inflammation in mice

(2012) Anita R. Alvheim et al.   BRITISH JOURNAL OF NUTRITION

Peripheral Cannabinoid-1 Receptor Inverse Agonism Reduces Obesity by Reversing Leptin Resistance

(2012) Joseph Tam et al.   Cell Metabolism

Anti-obesity efficacy of LH-21, a cannabinoid CB1 receptor antagonist with poor brain penetration, in diet-induced obese rats

(2011) Mónica Alonso et al.   BRITISH JOURNAL OF PHARMACOLOGY

Role for Cannabinoid Receptors in Human Proximal Tubular Hypertrophy

(2011) Kayte A. Jenkin et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

A New Perspective of Cannabinoid 1 Receptor Antagonists: Approaches Toward Peripheral CB1R Blockers without Crossing the Blood-Brain Barrier

(2011) Yen-Ku Wu et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Cannabinoid receptor agonists and antagonists stimulate insulin secretion from isolated human islets of Langerhans

(2011) C. Li et al.   DIABETES OBESITY & METABOLISM

Acute cannabinoid receptor type 1 (CB1R) modulation influences insulin sensitivity by an effect outside the central nervous system in mice

(2011) D. Song et al.   DIABETOLOGIA

The critical role of JNK in the ER-mitochondrial crosstalk during apoptotic cell death

(2011) Gaurav Verma et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The Highs and Lows of Cannabinoid Receptor Expression in Disease: Mechanisms and Their Therapeutic Implications

(2011) L. K. Miller et al.   PHARMACOLOGICAL REVIEWS

Expression of the cannabinoid system in muscle: effects of a high-fat diet and CB1receptor blockade

(2010) Ana Crespillo et al.   BIOCHEMICAL JOURNAL

CB1 Signaling in Forebrain and Sympathetic Neurons Is a Key Determinant of Endocannabinoid Actions on Energy Balance

(2010) Carmelo Quarta et al.   Cell Metabolism

CB1 Cannabinoid Receptors and their Associated Proteins

(2010) Allyn Howlett et al.   CURRENT MEDICINAL CHEMISTRY

CB1 Antagonism Exerts Specific Molecular Effects on Visceral and Subcutaneous Fat and Reverses Liver Steatosis in Diet-Induced Obese Mice

(2010) T. Jourdan et al.   DIABETES

Effects of in vitro antagonism of endocannabinoid-1 receptors on the glucose transport system in normal and insulin-resistant rat skeletal muscle

(2010) K. A. Lindborg et al.   DIABETES OBESITY & METABOLISM

Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity

(2010) Joseph Tam et al.   JOURNAL OF CLINICAL INVESTIGATION

The endocannabinoid signaling system: a marriage of PUFA and musculoskeletal health

(2010) Bruce A. Watkins et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Nitric Oxide Signaling in Brain Function, Dysfunction, and Dementia

(2010) Joern R. Steinert et al.   NEUROSCIENTIST

Regulation of MAP Kinase-Directed Mitogenic and Protein Kinase B-Mediated Signaling by Cannabinoid Receptor Type 1 in Skeletal Muscle Cells

(2009) C. Lipina et al.   DIABETES

Endocannabinoids and Their Receptors as Targets for Obesity Therapy

(2009) Annette D. de Kloet et al.   ENDOCRINOLOGY

Peripherally acting CB1-receptor antagonist: the relative importance of central and peripheral CB1 receptors in adiposity control

(2009) M-H Son et al.   INTERNATIONAL JOURNAL OF OBESITY

Signal transduction of the CB1 cannabinoid receptor

(2009) Gábor Turu et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Potent Antidiabetic Effects of Rivoglitazone, a Novel Peroxisome Proliferator–Activated Receptor-γ Agonist, in Obese Diabetic Rodent Models

(2009) Shoichi Kanda et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Altered pattern of cannabinoid type 1 receptor expression in adipose tissue of dysmetabolic and overweight patients

(2009) Riccardo Sarzani et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Characterization of Anandamide-Stimulated Cannabinoid Receptor Signaling in Human ULTR Myometrial Smooth Muscle Cells

(2009) Paul J. Brighton et al.   MOLECULAR ENDOCRINOLOGY

The CB1 Antagonist Rimonabant Decreases Insulin Hypersecretion in Rat Pancreatic Islets

(2009) Lisa Getty-Kaushik et al.   Obesity

Sustained Weight Loss After Roux-en-Y Gastric Bypass Is Characterized by Down Regulation of Endocannabinoids and Mitochondrial Function

(2008) Ana Guijarro et al.   ANNALS OF SURGERY

Peripheral, but Not Central, CB1 Antagonism Provides Food Intake-Independent Metabolic Benefits in Diet-Induced Obese Rats

(2008) R. Nogueiras et al.   DIABETES

Cannabinoid type 1 receptors in human skeletal muscle cells participate in the negative crosstalk between fat and muscle

(2008) K. Eckardt et al.   DIABETOLOGIA

Increased Energy Expenditure Contributes More to the Body Weight-Reducing Effect of Rimonabant than Reduced Food Intake in Candy-Fed Wistar Rats

(2008) Andreas W. Herling et al.   ENDOCRINOLOGY

Nitric oxide levels in chronic liver disease patients with and without oesophageal varices

(2008) Assem M. El-Sherif et al.   Hepatology International

Endocannabinoid receptor 1 gene variations increase risk for obesity and modulate body mass index in European populations

(2008) Michael Benzinou et al.   HUMAN MOLECULAR GENETICS

Regional alterations in the endocannabinoid system in an animal model of depression: effects of concurrent antidepressant treatment

(2008) Matthew N. Hill et al.   JOURNAL OF NEUROCHEMISTRY

Central Versus Peripheral Antagonism of Cannabinoid CB1 Receptor in Obesity: Effects of LH-21, a Peripherally Acting Neutral Cannabinoid Receptor Antagonist, in Zucker Rats

(2008) F. J. Pavón et al.   JOURNAL OF NEUROENDOCRINOLOGY

The Cannabinoid CB1 Receptor Antagonist Rimonabant Stimulates 2-Deoxyglucose Uptake in Skeletal Muscle Cells by Regulating the Expression of Phosphatidylinositol-3-kinase

(2008) I. Esposito et al.   MOLECULAR PHARMACOLOGY

Novel aspects of adipocyte-induced skeletal muscle insulin resistance

(2008) Kristin Eckardt et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY