The cisplatin-based Pt(iv)-diclorofibrato multi-action anticancer prodrug exhibits excellent performances also under hypoxic conditions
出版年份 2018 全文链接
标题
The cisplatin-based Pt(iv)-diclorofibrato multi-action anticancer prodrug exhibits excellent performances also under hypoxic conditions
作者
关键词
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出版物
DALTON TRANSACTIONS
Volume 47, Issue 25, Pages 8268-8282
出版商
Royal Society of Chemistry (RSC)
发表日期
2018-06-01
DOI
10.1039/c7dt04614f
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Research progress in modern structure of platinum complexes
- (2017) Linkui Bai et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Comparative studies of oxaliplatin-based platinum(iv) complexes in different in vitro and in vivo tumor models
- (2017) Simone Göschl et al. Metallomics
- The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
- (2016) Timothy C. Johnstone et al. CHEMICAL REVIEWS
- Platinum(iv) anticancer prodrugs – hypotheses and facts
- (2016) Dan Gibson DALTON TRANSACTIONS
- Antiproliferative activity of a series of cisplatin-based Pt(iv)-acetylamido/carboxylato prodrugs
- (2016) Mauro Ravera et al. DALTON TRANSACTIONS
- Prediction of logP for Pt(II) and Pt(IV) complexes: Comparison of statistical and quantum-chemistry based approaches
- (2016) Igor V. Tetko et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Fenofibrate reduces cisplatin-induced apoptosis of renal proximal tubular cells via inhibition of JNK and p38 pathways
- (2016) Penjai Thongnuanjan et al. JOURNAL OF TOXICOLOGICAL SCIENCES
- Behavior of platinum(iv) complexes in models of tumor hypoxia: cytotoxicity, compound distribution and accumulation
- (2016) Ekaterina Schreiber-Brynzak et al. Metallomics
- Pt(iv) derivatives of cisplatin and oxaliplatin with phenylbutyrate axial ligands are potent cytotoxic agents that act by several mechanisms of action
- (2016) Raji Raveendran et al. Chemical Science
- New insights into the molecular and epigenetic effects of antitumor Pt(IV)-valproic acid conjugates in human ovarian cancer cells
- (2015) Vojtech Novohradsky et al. BIOCHEMICAL PHARMACOLOGY
- Unprecedented one-pot synthesis of an unsymmetrical cisplatin-based Pt(iv)–acetamidato complex
- (2015) Giorgio Pelosi et al. CHEMICAL COMMUNICATIONS
- Microwave-assisted synthesis of the anticancer drug cisplatin, cis-[Pt(NH3)2Cl2]
- (2015) Emanuele Petruzzella et al. DALTON TRANSACTIONS
- Host–guest inclusion systems of Pt(IV)-bis(benzoato) anticancer drug candidates and cyclodextrins
- (2015) Mauro Ravera et al. INORGANICA CHIMICA ACTA
- Application of microwave-assisted heating to the synthesis of Pt(II) complexes
- (2015) Elisabetta Gabano et al. INORGANICA CHIMICA ACTA
- Cellular trafficking, accumulation and DNA platination of a series of cisplatin-based dicarboxylato Pt(IV) prodrugs
- (2015) Mauro Ravera et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Implications of a peroxisome proliferator-activated receptor alpha (PPARα) ligand clofibrate in breast cancer
- (2015) Karthic Chandran et al. Oncotarget
- Accurate prediction of 195Pt NMR chemical shifts for a series of Pt(ii) and Pt(iv) antitumor agents by a non-relativistic DFT computational protocol
- (2014) Athanassios C. Tsipis et al. DALTON TRANSACTIONS
- Pros and cons of bifunctional platinum(iv) antitumor prodrugs: two are (not always) better than one
- (2014) Elisabetta Gabano et al. DALTON TRANSACTIONS
- The potential role of HIF on tumour progression and dissemination
- (2014) Sandeep Unwith et al. INTERNATIONAL JOURNAL OF CANCER
- Effects of hypoxia on human cancer cell line chemosensitivity
- (2013) Sara Strese et al. BMC CANCER
- Clofibrate Induces Heme Oxygenase 1 Expression through a PPARa-Independent Mechanism in Human Cancer Cells
- (2013) Shuai Wang et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- A map of the PPARα transcription regulatory network for primary human hepatocytes
- (2013) Patrick D. McMullen et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Antiproliferative activity of Pt(IV)-bis(carboxylato) conjugates on malignant pleural mesothelioma cells
- (2013) Manuela Alessio et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Hypoxia–Induced Cytotoxic Drug Resistance in Osteosarcoma Is Independent of HIF-1Alpha
- (2013) Jennifer Adamski et al. PLoS One
- Hypoxia-Inducible Factors in Physiology and Medicine
- (2012) Gregg L. Semenza CELL
- Facile Preparation of Mono-, Di- and Mixed-Carboxylato Platinum(IV) Complexes for Versatile Anticancer Prodrug Design
- (2012) Jenny Z. Zhang et al. CHEMISTRY-A EUROPEAN JOURNAL
- Molecular interaction fields vs. quantum-mechanical-based descriptors in the modelling of lipophilicity of platinum(iv) complexes
- (2012) Giuseppe Ermondi et al. DALTON TRANSACTIONS
- Activation of Peroxisome Proliferator-activated Receptor α (PPARα) Suppresses Hypoxia-inducible Factor-1α (HIF-1α) Signaling in Cancer Cells
- (2012) Jundong Zhou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hypoxia modulation of peroxisome proliferator-activated receptors (PPARs) in human glioblastoma stem cells. Implications for therapy
- (2012) Renato Galzio et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- What do we know about the reduction of Pt(IV) pro-drugs?
- (2012) Ezequiel Wexselblatt et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Evaluation of Platinum-Ethacrynic Acid Conjugates in the Treatment of Mesothelioma
- (2011) Ilaria Zanellato et al. ChemMedChem
- Preparation of cisplatin using microwave heating and continuous-flow processing as tools
- (2011) Elizabeth A. Pedrick et al. INORGANIC CHEMISTRY COMMUNICATIONS
- Protein and its function based on a subcellular localization
- (2011) Jana Ćmielová et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Hypoxia induces peroxisome proliferator-activated receptor α (PPARα) and lipid metabolism peroxisomal enzymes in human glioblastoma cells
- (2011) G. Laurenti et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Molecular mechanisms of cisplatin resistance
- (2011) L Galluzzi et al. ONCOGENE
- Valproic acid overcomes hypoxia-induced resistance to apoptosis
- (2011) ŠIMON CIPRO et al. ONCOLOGY REPORTS
- HIF-1 as a Target for Cancer Chemotherapy, Chemosensitization and Chemoprevention
- (2011) Elena Monti et al. Current Molecular Pharmacology
- In vitro anti-mesothelioma activity of cisplatin–gemcitabine combinations: evidence for sequence-dependent effects
- (2010) Ilaria Zanellato et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method
- (2010) T.-C. Chou CANCER RESEARCH
- New reduction pathways for ctc-[PtCl2(CH3CO2)2(NH3)(Am)] anticancer prodrugs
- (2010) Alina Nemirovski et al. CHEMICAL COMMUNICATIONS
- Molecular and statistical modeling of reduction peak potential and lipophilicity of platinum(IV) complexes
- (2010) James A. Platts et al. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
- Antiproliferative Pt(IV) complexes: synthesis, biological activity, and quantitative structure–activity relationship modeling
- (2010) Paola Gramatica et al. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
- Cytotoxic Properties of Clofibrate and other Peroxisome Proliferators: Relevance to Cancer Progression
- (2009) F. Penna et al. CURRENT MEDICINAL CHEMISTRY
- The mechanism of action of platinum anticancer agents—what do we really know about it?
- (2009) Dan Gibson DALTON TRANSACTIONS
- Applications of heteronuclear NMR spectroscopy in biological and medicinal inorganic chemistry
- (2008) Luca Ronconi et al. COORDINATION CHEMISTRY REVIEWS
- [1H,15N] Heteronuclear Single Quantum Coherence NMR Study of the Mechanism of Aquation of Platinum(IV) Ammine Complexes
- (2008) Murray S. Davies et al. INORGANIC CHEMISTRY
- Calculation of lipophilicity for Pt(II) complexes: Experimental comparison of several methods
- (2008) Igor V. Tetko et al. JOURNAL OF INORGANIC BIOCHEMISTRY
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