Pt(iv) derivatives of cisplatin and oxaliplatin with phenylbutyrate axial ligands are potent cytotoxic agents that act by several mechanisms of action
出版年份 2016 全文链接
标题
Pt(iv) derivatives of cisplatin and oxaliplatin with phenylbutyrate axial ligands are potent cytotoxic agents that act by several mechanisms of action
作者
关键词
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出版物
Chemical Science
Volume 7, Issue 3, Pages 2381-2391
出版商
Royal Society of Chemistry (RSC)
发表日期
2016-01-16
DOI
10.1039/c5sc04205d
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- New insights into the molecular and epigenetic effects of antitumor Pt(IV)-valproic acid conjugates in human ovarian cancer cells
- (2015) Vojtech Novohradsky et al. BIOCHEMICAL PHARMACOLOGY
- Cellular trafficking, accumulation and DNA platination of a series of cisplatin-based dicarboxylato Pt(IV) prodrugs
- (2015) Mauro Ravera et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- A novel valproic acid prodrug as an anticancer agent that enhances doxorubicin anticancer activity and protects normal cells against its toxicity in vitro and in vivo
- (2014) Nataly Tarasenko et al. BIOCHEMICAL PHARMACOLOGY
- Antitumor platinum(IV) derivatives of oxaliplatin with axial valproato ligands
- (2014) Vojtech Novohradsky et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Novel Antitumor Cisplatin and Transplatin Derivatives Containing 1-Methyl-7-Azaindole: Synthesis, Characterization, and Cellular Responses
- (2014) Jitka Pracharova et al. JOURNAL OF MEDICINAL CHEMISTRY
- A histone deacetylase inhibitor YCW1 with antitumor and antimetastasis properties enhances cisplatin activity against non-small cell lung cancer in preclinical studies
- (2013) Wei-Jan Huang et al. CANCER LETTERS
- Synthetic Methods for the Preparation of Platinum Anticancer Complexes
- (2013) Justin J. Wilson et al. CHEMICAL REVIEWS
- Apoptosis Regulation at the Mitochondrial Outer Membrane
- (2013) Laura A. Gillies et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Antiproliferative activity of Pt(IV)-bis(carboxylato) conjugates on malignant pleural mesothelioma cells
- (2013) Manuela Alessio et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Combination therapy: Histone deacetylase inhibitors and platinum-based chemotherapeutics for cancer
- (2012) Himashinie V.K. Diyabalanage et al. CANCER LETTERS
- Facile Preparation of Mono-, Di- and Mixed-Carboxylato Platinum(IV) Complexes for Versatile Anticancer Prodrug Design
- (2012) Jenny Z. Zhang et al. CHEMISTRY-A EUROPEAN JOURNAL
- What do we know about the reduction of Pt(IV) pro-drugs?
- (2012) Ezequiel Wexselblatt et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Unsymmetric Mono- and Dinuclear Platinum(IV) Complexes Featuring an Ethylene Glycol Moiety: Synthesis, Characterization, and Biological Activity
- (2012) Verena Pichler et al. JOURNAL OF MEDICINAL CHEMISTRY
- Tuning the Activity of Platinum(IV) Anticancer Complexes through Asymmetric Acylation
- (2012) Chee Fei Chin et al. JOURNAL OF MEDICINAL CHEMISTRY
- Valuable Insight into the Anticancer Activity of the Platinum-Histone Deacetylase Inhibitor Conjugate, cis-[Pt(NH3)2malSAHA–2H)]
- (2012) Viktor Brabec et al. MOLECULAR PHARMACEUTICS
- Conjugate of Pt(IV)–Histone Deacetylase Inhibitor as a Prodrug for Cancer Chemotherapy
- (2012) Jun Yang et al. MOLECULAR PHARMACEUTICS
- Platinum-(IV)-derivative satraplatin induced G2/M cell cycle perturbation via p53-p21waf1/cip1-independent pathway in human colorectal cancer cells
- (2011) Murugan Kalimutho et al. ACTA PHARMACOLOGICA SINICA
- Non-Classical Structures Among Current Platinum Complexes with Potential as Antitumor Drugs
- (2011) Adoracion G. Quiroga CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Anticancer Platinum (IV) Prodrugs with Novel Modes of Activity
- (2011) Chee Fei Chin et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- The effect of combined treatment with cisplatin and histone deacetylase inhibitors on HeLa cells
- (2011) Ke Long Jin et al. Journal of Gynecologic Oncology
- Novel trans-platinum complexes of the histone deacetylase inhibitor valproic acid; synthesis, in vitro cytotoxicity and mutagenicity
- (2011) Darren M. Griffith et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Phenylbutyrate inhibits homologous recombination induced by camptothecin and methyl methanesulfonate
- (2011) Gitte S. Kaiser et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- The status of platinum anticancer drugs in the clinic and in clinical trials
- (2010) Nial J. Wheate et al. DALTON TRANSACTIONS
- Short-Chain HDAC Inhibitors Differentially Affect Vertebrate Development and Neuronal Chromatin
- (2010) Daniel M. Fass et al. ACS Medicinal Chemistry Letters
- A novel anti-cancer bifunctional platinum drug candidate with dual DNA binding and histone deacetylase inhibitory activity
- (2009) Darren Griffith et al. CHEMICAL COMMUNICATIONS
- Status of Non-Classical Mononuclear Platinum Anticancer Drug Development
- (2009) Jinchao Zhang et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Histone deacetylase inhibitors in cancer therapy
- (2008) Min-Jung Lee et al. CURRENT OPINION IN ONCOLOGY
- Phenylbutyrate interferes with the Fanconi anemia and BRCA pathway and sensitizes head and neck cancer cells to cisplatin
- (2008) Kyunghee Burkitt et al. Molecular Cancer
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