How structural elements evolving from bacterial to human SLC6 transporters enabled new functional properties

标题
How structural elements evolving from bacterial to human SLC6 transporters enabled new functional properties
作者
关键词
Dopamine transport, SLC6 neurotransmitter transporters, Evolutionary gain of function, Molecular dynamics simulations, Markov state models, Reverse transport, SERT, Regulation by PIP<sub>2</sub>, Regulation by phosphorylation, posttranslational modifications
出版物
BMC BIOLOGY
Volume 16, Issue 1, Pages -
出版商
Springer Nature
发表日期
2018-03-14
DOI
10.1186/s12915-018-0495-6

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