Missense dopamine transporter mutations associate with adult parkinsonism and ADHD

Dopamine transporter deficiency syndrome: phenotypic spectrum from infancy to adulthood

(2014) Joanne Ng et al.   BRAIN

PICK1 Deficiency Impairs Secretory Vesicle Biogenesis and Leads to Growth Retardation and Decreased Glucose Tolerance

(2014) Birgitte Holst et al.   PLOS BIOLOGY

Transgenic mouse models for ADHD

(2013) Damiana Leo et al.   CELL AND TISSUE RESEARCH

How LeuT shapes our understanding of the mechanisms of sodium-coupled neurotransmitter transporters

(2013) Aravind Penmatsa et al.   JOURNAL OF PHYSIOLOGY-LONDON

De novo mutation in the dopamine transporter gene associates dopamine dysfunction with autism spectrum disorder

(2013) P J Hamilton et al.   MOLECULAR PSYCHIATRY

X-ray structure of dopamine transporter elucidates antidepressant mechanism

(2013) Aravind Penmatsa et al.   NATURE

Interpreting the role of de novo protein-coding mutations in neuropsychiatric disease

(2013) Jacob Gratten et al.   NATURE GENETICS

Combined PET/MR imaging in neurology: MR-based attenuation correction implies a strong spatial bias when ignoring bone

(2013) Flemming Littrup Andersen et al.   NEUROIMAGE

Monogenic Parkinson's disease and parkinsonism: Clinical phenotypes and frequencies of known mutations

(2013) Andreas Puschmann   PARKINSONISM & RELATED DISORDERS

Chloride binding site of neurotransmitter sodium symporters

(2013) A. K. Kantcheva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A C-terminal PDZ domain-binding sequence is required for striatal distribution of the dopamine transporter

(2013) Mattias Rickhag et al.   Nature Communications

Striatal Dopamine Transporter Alterations in ADHD: Pathophysiology or Adaptation to Psychostimulants? A Meta-Analysis

(2012) Paolo Fusar-Poli et al.   AMERICAN JOURNAL OF PSYCHIATRY

Ion-Controlled Conformational Dynamics in the Outward-Open Transition from an Occluded State of LeuT

(2012) Chunfeng Zhao et al.   BIOPHYSICAL JOURNAL

Schizophrenia Genetics: Putting All the Pieces Together

(2012) Simon L. Girard et al.   Current Neurology and Neuroscience Reports

Attention Deficit/Hyperactivity Disorder-Derived Coding Variation in the Dopamine Transporter Disrupts Microdomain Targeting and Trafficking Regulation

(2012) D. Sakrikar et al.   JOURNAL OF NEUROSCIENCE

X-ray structures of LeuT in substrate-free outward-open and apo inward-open states

(2012) Harini Krishnamurthy et al.   NATURE

De novo mutations in human genetic disease

(2012) Joris A. Veltman et al.   NATURE REVIEWS GENETICS

Reduced striatal volumes in Parkinson’s disease: a magnetic resonance imaging study

(2012) Toni L Pitcher et al.   Translational Neurodegeneration

Parkinson disease: Insights in clinical, genetic and pathological features of monogenic disease subtypes

(2011) David Crosiers et al.   JOURNAL OF CHEMICAL NEUROANATOMY

The monoamine neurotransmitter disorders: an expanding range of neurological syndromes

(2011) Manju A Kurian et al.   LANCET NEUROLOGY

The genetics of attention deficit/hyperactivity disorder in adults, a review

(2011) B Franke et al.   MOLECULAR PSYCHIATRY

How Addictive Drugs Disrupt Presynaptic Dopamine Neurotransmission

(2011) David Sulzer   NEURON

Neurobiology of Attention Deficit/Hyperactivity Disorder

(2011) DIANE PURPER-OUAKIL et al.   PEDIATRIC RESEARCH

SLC6 Neurotransmitter Transporters: Structure, Function, and Regulation

(2011) A. S. Kristensen et al.   PHARMACOLOGICAL REVIEWS

The Substrate-Driven Transition to an Inward-Facing Conformation in the Functional Mechanism of the Dopamine Transporter

(2011) Jufang Shan et al.   PLoS One

Cortical hypometabolism and hypoperfusion in Parkinson’s disease is extensive: probably even at early disease stages

(2010) Per Borghammer et al.   Brain Structure & Function

Dysregulation of Dopamine Transporters via Dopamine D2 Autoreceptors Triggers Anomalous Dopamine Efflux Associated with Attention-Deficit Hyperactivity Disorder

(2010) E. Bowton et al.   JOURNAL OF NEUROSCIENCE

Clinical and molecular characterisation of hereditary dopamine transporter deficiency syndrome: an observational cohort and experimental study

(2010) Manju A Kurian et al.   LANCET NEUROLOGY

Ion/substrate-dependent conformational dynamics of a bacterial homolog of neurotransmitter:sodium symporters

(2010) Derek P Claxton et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cerebrospinal fluid metabolite and nigrostriatal dopaminergic function in Parkinson’s disease

(2009) K. Ishibashi et al.   ACTA NEUROLOGICA SCANDINAVICA

Candidate gene studies of ADHD: a meta-analytic review

(2009) Ian R. Gizer et al.   HUMAN GENETICS

Infantile parkinsonism-dystonia: a dopamine “transportopathy”

(2009) Craig Blackstone   JOURNAL OF CLINICAL INVESTIGATION

Homozygous loss-of-function mutations in the gene encoding the dopamine transporter are associated with infantile parkinsonism-dystonia

(2009) Manju A. Kurian et al.   JOURNAL OF CLINICAL INVESTIGATION

Visualization of Dopamine Transporter Trafficking in Live Neurons by Use of Fluorescent Cocaine Analogs

(2009) J. Eriksen et al.   JOURNAL OF NEUROSCIENCE

A single nucleotide polymorphism in the human serotonin transporter introduces a new site for N-linked glycosylation

(2009) Trine N. Rasmussen et al.   NEUROPHARMACOLOGY

Domain coupling in asymmetric lipid bilayers

(2008) Volker Kiessling et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Anomalous Dopamine Release Associated with a Human Dopamine Transporter Coding Variant

(2008) M. S. Mazei-Robison et al.   JOURNAL OF NEUROSCIENCE

The Mechanism of a Neurotransmitter:Sodium Symporter—Inward Release of Na+ and Substrate Is Triggered by Substrate in a Second Binding Site

(2008) Lei Shi et al.   MOLECULAR CELL

The binding sites for cocaine and dopamine in the dopamine transporter overlap

(2008) Thijs Beuming et al.   NATURE NEUROSCIENCE

Correlation between changes in CSF dopamine turnover and development of dyskinesia in Parkinson's disease

(2008) Gianluigi Lunardi et al.   PARKINSONISM & RELATED DISORDERS