The Eukaryotic CMG Helicase at the Replication Fork: Emerging Architecture Reveals an Unexpected Mechanism
出版年份 2018 全文链接
标题
The Eukaryotic CMG Helicase at the Replication Fork: Emerging Architecture Reveals an Unexpected Mechanism
作者
关键词
-
出版物
BIOESSAYS
Volume 40, Issue 3, Pages 1700208
出版商
Wiley
发表日期
2018-02-06
DOI
10.1002/bies.201700208
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Mcm10 regulates DNA replication elongation by stimulating the CMG replicative helicase
- (2017) Marko Lõoke et al. GENES & DEVELOPMENT
- Chromatin Controls DNA Replication Origin Selection, Lagging-Strand Synthesis, and Replication Fork Rates
- (2017) Christoph F. Kurat et al. MOLECULAR CELL
- Chromatin Constrains the Initiation and Elongation of DNA Replication
- (2017) Sujan Devbhandari et al. MOLECULAR CELL
- How the Eukaryotic Replisome Achieves Rapid and Efficient DNA Replication
- (2017) Joseph T.P. Yeeles et al. MOLECULAR CELL
- Open-ringed structure of the Cdt1–Mcm2–7 complex as a precursor of the MCM double hexamer
- (2017) Yuanliang Zhai et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structural basis of Mcm2–7 replicative helicase loading by ORC–Cdc6 and Cdt1
- (2017) Zuanning Yuan et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Cryo-EM structure of Mcm2-7 double hexamer on DNA suggests a lagging-strand DNA extrusion model
- (2017) Yasunori Noguchi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Single-molecule visualization ofSaccharomyces cerevisiaeleading-strand synthesis reveals dynamic interaction between MTC and the replisome
- (2017) Jacob S. Lewis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation
- (2017) Roxana Georgescu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CMG–Pol epsilon dynamics suggests a mechanism for the establishment of leading-strand synthesis in the eukaryotic replisome
- (2017) Jin Chuan Zhou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Quality control mechanisms exclude incorrect polymerases from the eukaryotic replication fork
- (2017) Grant D. Schauer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bidirectional eukaryotic DNA replication is established by quasi-symmetrical helicase loading
- (2017) Gideon Coster et al. SCIENCE
- Open-ringed structure of the Cdt1–Mcm2–7 complex as a precursor of the MCM double hexamer
- (2017) Yuanliang Zhai et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structural basis of Mcm2–7 replicative helicase loading by ORC–Cdc6 and Cdt1
- (2017) Zuanning Yuan et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Chromosome Duplication in Saccharomyces cerevisiae
- (2016) S. P. Bell et al. GENETICS
- Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation
- (2016) Zuanning Yuan et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Archaeal orthologs of Cdc45 and GINS form a stable complex that stimulates the helicase activity of MCM
- (2016) Yuli Xu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cryo-EM structures of the eukaryotic replicative helicase bound to a translocation substrate
- (2016) Ferdos Abid Ali et al. Nature Communications
- Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation
- (2016) Zuanning Yuan et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Single-Molecule Studies of Origin Licensing Reveal Mechanisms Ensuring Bidirectional Helicase Loading
- (2015) Simina Ticau et al. CELL
- Reconsidering DNA Polymerases at the Replication Fork in Eukaryotes
- (2015) Bruce Stillman MOLECULAR CELL
- A Major Role of DNA Polymerase δ in Replication of Both the Leading and Lagging DNA Strands
- (2015) Robert E. Johnson et al. MOLECULAR CELL
- Structure of the eukaryotic MCM complex at 3.8 Å
- (2015) Ningning Li et al. NATURE
- Regulated eukaryotic DNA replication origin firing with purified proteins
- (2015) Joseph T. P. Yeeles et al. NATURE
- Tracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation
- (2015) Anders R Clausen et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The architecture of a eukaryotic replisome
- (2015) Jingchuan Sun et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structure and mechanism of the ATPase that powers viral genome packaging
- (2015) Brendan J. Hilbert et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cdc45 (cell division cycle protein 45) guards the gate of the Eukaryote Replisome helicase stabilizing leading strand engagement
- (2015) Tatjana Petojevic et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation
- (2015) Anders R Clausen et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The architecture of a eukaryotic replisome
- (2015) Jingchuan Sun et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Archaeal MCM Proteins as an Analog for the Eukaryotic Mcm2–7 Helicase to Reveal Essential Features of Structure and Function
- (2015) Justin M. Miller et al. ARCHAEA-AN INTERNATIONAL MICROBIOLOGICAL JOURNAL
- Reconstitution of a eukaryotic replisome reveals suppression mechanisms that define leading/lagging strand operation
- (2015) Roxana E Georgescu et al. eLife
- A unique DNA entry gate serves for regulated loading of the eukaryotic replicative helicase MCM2–7 onto DNA
- (2014) Stefan A. Samel et al. GENES & DEVELOPMENT
- Strand-Specific Analysis Shows Protein Binding at Replication Forks and PCNA Unloading from Lagging Strands when Forks Stall
- (2014) Chuanhe Yu et al. MOLECULAR CELL
- A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome
- (2014) Aline C. Simon et al. NATURE
- Delivering nonidentical twins
- (2014) Thomas A Kunkel et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Mechanism of asymmetric polymerase assembly at the eukaryotic replication fork
- (2014) Roxana E Georgescu et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- CMG helicase and DNA polymerase form a functional 15-subunit holoenzyme for eukaryotic leading-strand DNA replication
- (2014) L. D. Langston et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dynamic look at DNA unwinding by a replicative helicase
- (2014) Seung-Jae Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A conserved MCM single-stranded DNA binding element is essential for replication initiation
- (2014) Clifford A Froelich et al. eLife
- Cryo-EM structure of a helicase loading intermediate containing ORC–Cdc6–Cdt1–MCM2-7 bound to DNA
- (2013) Jingchuan Sun et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Principles and Concepts of DNA Replication in Bacteria, Archaea, and Eukarya
- (2013) M. O'Donnell et al. Cold Spring Harbor Perspectives in Biology
- The Minichromosome Maintenance Replicative Helicase
- (2013) S. D. Bell et al. Cold Spring Harbor Perspectives in Biology
- Clamp loader ATPases and the evolution of DNA replication machinery
- (2012) Brian A Kelch et al. BMC BIOLOGY
- The Hexameric Helicase DnaB Adopts a Nonplanar Conformation during Translocation
- (2012) Ornchuma Itsathitphaisarn et al. CELL
- Mcm10 Plays a Role in Functioning of the Eukaryotic Replicative DNA Helicase, Cdc45-Mcm-GINS
- (2012) George Watase et al. CURRENT BIOLOGY
- A structural framework for replication origin opening by AAA+ initiation factors
- (2012) Karl E Duderstadt et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Mcm10 plays an essential role in origin DNA unwinding after loading of the CMG components
- (2012) Mai Kanke et al. EMBO JOURNAL
- Mcm10 associates with the loaded DNA helicase at replication origins and defines a novel step in its activation
- (2012) Frederick van Deursen et al. EMBO JOURNAL
- Properties of the human Cdc45/Mcm2-7/GINS helicase complex and its action with DNA polymerase in rolling circle DNA synthesis
- (2012) Y.-H. Kang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ATP-dependent conformational dynamics underlie the functional asymmetry of the replicative helicase from a minimalist eukaryote
- (2012) Artem Y. Lyubimov et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ClpXP, an ATP-powered unfolding and protein-degradation machine
- (2011) Tania A. Baker et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Eukaryotic Origin-Dependent DNA Replication In Vitro Reveals Sequential Action of DDK and S-CDK Kinases
- (2011) Ryan C. Heller et al. CELL
- Selective Bypass of a Lagging Strand Roadblock by the Eukaryotic Replicative DNA Helicase
- (2011) Yu V. Fu et al. CELL
- The nuts and bolts of ring-translocase structure and mechanism
- (2011) Artem Y Lyubimov et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- The structural basis for MCM2–7 helicase activation by GINS and Cdc45
- (2011) Alessandro Costa et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The Major Roles of DNA Polymerases Epsilon and Delta at the Eukaryotic Replication Fork Are Evolutionarily Conserved
- (2011) Izumi Miyabe et al. PLoS Genetics
- Uncoupling of Sister Replisomes during Eukaryotic DNA Replication
- (2010) Hasan Yardimci et al. MOLECULAR CELL
- Activation of the MCM2-7 Helicase by Association with Cdc45 and GINS Proteins
- (2010) Ivar Ilves et al. MOLECULAR CELL
- Active and passive mechanisms of helicases
- (2010) Maria Manosas et al. NUCLEIC ACIDS RESEARCH
- Concerted Loading of Mcm2–7 Double Hexamers around DNA during DNA Replication Origin Licensing
- (2009) Dirk Remus et al. CELL
- Running in Reverse: The Structural Basis for Translocation Polarity in Hexameric Helicases
- (2009) Nathan D. Thomsen et al. CELL
- A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase α within the eukaryotic replisome
- (2009) Agnieszka Gambus et al. EMBO JOURNAL
- New ATPase regulators—p97 goes to the PUB
- (2009) Louise Madsen et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication
- (2009) C. Evrin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- On helicases and other motor proteins
- (2008) Eric J Enemark et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Subunit Organization of Mcm2-7 and the Unequal Role of Active Sites in ATP Hydrolysis and Viability
- (2008) M. L. Bochman et al. MOLECULAR AND CELLULAR BIOLOGY
- Division of Labor at the Eukaryotic Replication Fork
- (2008) Stephanie A. Nick McElhinny et al. MOLECULAR CELL
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now