Systems-wide Experimental and Modeling Analysis of Insulin Signaling through Forkhead Box Protein O1 (FOXO1) in Human Adipocytes, Normally and in Type 2 Diabetes

The pathogenesis of insulin resistance: integrating signaling pathways and substrate flux

(2016) Varman T. Samuel et al.   JOURNAL OF CLINICAL INVESTIGATION

Systematic identification of signal integration by protein kinase A

(2015) Marie Filteau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sex differences in the brain: a whole body perspective

(2015) Geert J. de Vries et al.   Biology of Sex Differences

FoxO1 at the nexus between fat catabolism and longevity pathways

(2014) Daniele Lettieri Barbato et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The Expression of FoxO1 in Placenta and Omental Adipose Tissue of Gestational Diabetes Mellitus

(2014) Y. Xu et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

A Single Mechanism Can Explain Network-wide Insulin Resistance in Adipocytes from Obese Patients with Type 2 Diabetes

(2014) Elin Nyman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impaired Akt phosphorylation in insulin-resistant human muscle is accompanied by selective and heterogeneous downstream defects

(2013) K. T. Tonks et al.   DIABETOLOGIA

Insulin Signaling in Type 2 Diabetes

(2013) Cecilia Brännmark et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FOXOs: signalling integrators for homeostasis maintenance

(2013) Astrid Eijkelenboom et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

mTOR inhibition with rapamycin causes impaired insulin signalling and glucose uptake in human subcutaneous and omental adipocytes

(2012) Maria J. Pereira et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

FoxO1, the transcriptional chief of staff of energy metabolism

(2011) Stavroula Kousteni   BONE

A Hierarchical Whole-body Modeling Approach Elucidates the Link betweenin VitroInsulin Signaling andin VivoGlucose Homeostasis

(2011) Elin Nyman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Lipolysis in Small and Large Fat Cells of the Same Subject

(2011) Jurga Laurencikiene et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The worldwide epidemiology of type 2 diabetes mellitus—present and future perspectives

(2011) Lei Chen et al.   Nature Reviews Endocrinology

Hyperinsulinemia leads to uncoupled insulin regulation of the GLUT4 glucose transporter and the FoxO1 transcription factor

(2011) E. Gonzalez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insulin-sensitive obesity

(2010) Nora Klöting et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Mass and Information Feedbacks through Receptor Endocytosis Govern Insulin Signaling as Revealed Using a Parameter-free Modeling Framework

(2010) Cecilia Brännmark et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1

(2010) T. Kantidakis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FoxO1 Haploinsufficiency Protects Against High-Fat Diet-Induced Insulin Resistance With Enhanced Peroxisome Proliferator-Activated Receptor   Activation in Adipose Tissue

(2009) J. J. Kim et al.   DIABETES

Adipocyte size predicts incidence of type 2 diabetes in women

(2009) Malin Lönn et al.   FASEB JOURNAL

MDM2 Acts Downstream of p53 as an E3 Ligase to Promote FOXO Ubiquitination and Degradation

(2009) Wei Fu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Density functional computational studies on (E)-2-[(2-Hydroxy-5-nitrophenyl)-iminiomethyl]-4-nitrophenolate

(2009) Hasan Tanak et al.   JOURNAL OF MOLECULAR MODELING

Characterization of Rictor Phosphorylation Sites Reveals Direct Regulation of mTOR Complex 2 by S6K1

(2009) C. C. Dibble et al.   MOLECULAR AND CELLULAR BIOLOGY

mTORC1-Activated S6K1 Phosphorylates Rictor on Threonine 1135 and Regulates mTORC2 Signaling

(2009) L.-A. Julien et al.   MOLECULAR AND CELLULAR BIOLOGY

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(2009) Anna Danielsson et al.   MOLECULAR MEDICINE

Rictor is a novel target of p70 S6 kinase-1

(2009) C Treins et al.   ONCOGENE

Arginine Methylation of FOXO Transcription Factors Inhibits Their Phosphorylation by Akt

(2008) Kazuyuki Yamagata et al.   MOLECULAR CELL