HIF-Prolyl Hydroxylase 2 Inhibition Enhances the Efficiency of Mesenchymal Stem Cell-Based Therapies for the Treatment of Critical Limb Ischemia

Molecular Imaging of the Paracrine Proangiogenic Effects of Progenitor Cell Therapy in Limb Ischemia

(2013) Jae Choon Ryu et al.   CIRCULATION

HIF-1α is upregulated in human mesenchymal stem cells

(2013) Sami Palomäki et al.   STEM CELLS

Exposure to cigarette smoke induces overexpression of von Hippel-Lindau tumor suppressor in mouse skeletal muscle

(2012) Vladimir T. Basic et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Pulmonary vascular disease in mice xenografted with human BM progenitors from patients with pulmonary arterial hypertension

(2012) K. Asosingh et al.   BLOOD

Ephrin-B2-Activated Peripheral Blood Mononuclear Cells From Diabetic Patients Restore Diabetes-Induced Impairment of Postischemic Neovascularization

(2012) D. Broqueres-You et al.   DIABETES

Transplantation of hypoxia preconditioned bone marrow mesenchymal stem cells enhances angiogenesis and neurogenesis after cerebral ischemia in rats

(2012) Ling Wei et al.   NEUROBIOLOGY OF DISEASE

Endothelial Nitric Oxide Synthase Overexpression Restores the Efficiency of Bone Marrow Mononuclear Cell-Based Therapy

(2011) Barend Mees et al.   AMERICAN JOURNAL OF PATHOLOGY

Hypoxia-inducible factors in human pulmonary arterial hypertension: a link to the intrinsic myeloid abnormalities

(2011) S. Farha et al.   BLOOD

Metabolic reprogramming by HIF-1 promotes the survival of bone marrow-derived angiogenic cells in ischemic tissue

(2011) S. Rey et al.   BLOOD

Angiogenic potential of BM MSCs derived from patients with critical leg ischemia

(2011) D M Smadja et al.   BONE MARROW TRANSPLANTATION

HIF-1α dysfunction in diabetes

(2011) Hariharan Thangarajah et al.   CELL CYCLE

Deregulation of microRNA-503 Contributes to Diabetes Mellitus–Induced Impairment of Endothelial Function and Reparative Angiogenesis After Limb Ischemia

(2011) Andrea Caporali et al.   CIRCULATION

Double Knockdown of Prolyl Hydroxylase and Factor-Inhibiting Hypoxia-Inducible Factor With Nonviral Minicircle Gene Therapy Enhances Stem Cell Mobilization and Angiogenesis After Myocardial Infarction

(2011) M. Huang et al.   CIRCULATION

Early endothelial progenitor cells in bone marrow are a biomarker of cell therapy success in patients with critical limb ischemia

(2011) David M. Smadja et al.   CYTOTHERAPY

Regulation of hypoxia-inducible factor 1 and the loss of the cellular response to hypoxia in diabetes

(2011) C. F. Bento et al.   DIABETOLOGIA

Adenovirus-mediated HIF-1α gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection

(2011) Xinguo Jiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis

(2011) Yukiji Takeda et al.   NATURE

Dissection of the Biphasic Nature of Hypoxia-Induced Motogenic Action in Bone Marrow-Derived Human Mesenchymal Stem Cells

(2011) Chiara Busletta et al.   STEM CELLS

Paracrine factors released by GATA-4 overexpressed mesenchymal stem cells increase angiogenesis and cell survival

(2010) Hongxia Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Thrombospondin-1 Is a Plasmatic Marker of Peripheral Arterial Disease That Modulates Endothelial Progenitor Cell Angiogenic Properties

(2010) David M. Smadja et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Regulation of monocyte subset systemic levels by distinct chemokine receptors controls post-ischaemic neovascularization

(2010) C. Cochain et al.   CARDIOVASCULAR RESEARCH

Hypoxia Preconditioned Mesenchymal Stem Cells Improve Vascular and Skeletal Muscle Fiber Regeneration After Ischemia Through a Wnt4-dependent Pathway

(2010) Lionel Leroux et al.   MOLECULAR THERAPY

Methylglyoxal Alters the Function and Stability of Critical Components of the Protein Quality Control

(2010) Carla Figueira Bento et al.   PLoS One

Hepatocyte Growth Factor or Vascular Endothelial Growth Factor Gene Transfer Maximizes Mesenchymal Stem Cell-Based Myocardial Salvage After Acute Myocardial Infarction

(2009) T. Deuse et al.   CIRCULATION

Inhibition of Prolyl Hydroxylase Domain Proteins Promotes Therapeutic Revascularization

(2009) Céline Loinard et al.   CIRCULATION

Hypoxic Preconditioning Enhances the Benefit of Cardiac Progenitor Cell Therapy for Treatment of Myocardial Infarction by Inducing CXCR4 Expression

(2009) Yao Liang Tang et al.   CIRCULATION RESEARCH

Ethanol Augments RANTES/CCL5 Expression in Rat Liver Sinusoidal Endothelial Cells and Human Endothelial Cells via Activation of NF- B, HIF-1 , and AP-1

(2009) S. M. Yeligar et al.   JOURNAL OF IMMUNOLOGY

Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease

(2009) Peter Fraisl et al.   NATURE REVIEWS DRUG DISCOVERY

Adenoviral transfer of HIF-1  enhances vascular responses to critical limb ischemia in diabetic mice

(2009) K. Sarkar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites

(2009) F. K. Swirski et al.   SCIENCE

Endostatin and angiostatin are increased in diabetic patients with coronary artery disease and associated with impaired coronary collateral formation

(2008) Neel R. Sodha et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Bone Morphogenetic Proteins 2 and 4 Are Selectively Expressed by Late Outgrowth Endothelial Progenitor Cells and Promote Neoangiogenesis

(2008) David M. Smadja et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Neurotrophin p75 Receptor (p75 NTR ) Promotes Endothelial Cell Apoptosis and Inhibits Angiogenesis

(2008) Andrea Caporali et al.   CIRCULATION RESEARCH

Engineering Robust and Functional Vascular Networks In Vivo With Human Adult and Cord Blood–Derived Progenitor Cells

(2008) Juan M. Melero-Martin et al.   CIRCULATION RESEARCH

Decreasing Intracellular Superoxide Corrects Defective Ischemia-induced New Vessel Formation in Diabetic Mice

(2008) Daniel J. Ceradini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Emerging hurdles in stem cell therapy for peripheral vascular disease

(2008) Xabier L. Aranguren et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Transplantation of hypoxia-preconditioned mesenchymal stem cells improves infarcted heart function via enhanced survival of implanted cells and angiogenesis

(2008) Xinyang Hu et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Bone marrow-derived mononuclear cell therapy induces distal angiogenesis after local injection in critical leg ischemia

(2008) Jean-Paul Duong Van Huyen et al.   MODERN PATHOLOGY

Stem-cell therapy for cardiac disease

(2008) Vincent F. M. Segers et al.   NATURE

PHDs overactivation during chronic hypoxia "desensitizes" HIF  and protects cells from necrosis

(2008) A. Ginouves et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stabilization of HIF-1  is critical to improve wound healing in diabetic mice

(2008) I. R. Botusan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reduction of myocardial infarct size by human mesenchymal stem cell conditioned medium

(2008) Leo Timmers et al.   Stem Cell Research

Hypoxic Preconditioning Results in Increased Motility and Improved Therapeutic Potential of Human Mesenchymal Stem Cells

(2008) Ivana Rosová et al.   STEM CELLS