Autism Spectrum Disorders and Schizophrenia Spectrum Disorders: Excitation/Inhibition Imbalance and Developmental Trajectories

mTOR, a Potential Target to Treat Autism Spectrum Disorder

(2016) Atsushi Sato   CNS & Neurological Disorders-Drug Targets

Reduced GABAergic Action in the Autistic Brain

(2016) Caroline E. Robertson et al.   CURRENT BIOLOGY

The National Institute of Mental Health Research Domain Criteria and Clinical Research in Child and Adolescent Psychiatry

(2016) Marjorie Garvey et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects

(2016) Yang Zhou et al.   NEURON

Are Hallucinations Due to an Imbalance Between Excitatory and Inhibitory Influences on the Brain?

(2016) Renaud Jardri et al.   SCHIZOPHRENIA BULLETIN

FOXG1-Dependent Dysregulation of GABA/Glutamate Neuron Differentiation in Autism Spectrum Disorders

(2015) Jessica Mariani et al.   CELL

Common Mechanisms of Excitatory and Inhibitory Imbalance in Schizophrenia and Autism Spectrum Disorders

(2015) R. Gao et al.   CURRENT MOLECULAR MEDICINE

Review: Cortical construction in autism spectrum disorder: columns, connectivity and the subplate

(2015) Jeffrey J. Hutsler et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

GABAB Receptor Agonist R-Baclofen Reverses Social Deficits and Reduces Repetitive Behavior in Two Mouse Models of Autism

(2015) J L Silverman et al.   NEUROPSYCHOPHARMACOLOGY

Schizophrenia and Autism--Related Disorders

(2015) R. E. Hommer et al.   SCHIZOPHRENIA BULLETIN

Glial cells as key players in schizophrenia pathology: recent insights and concepts of therapy

(2015) Hans-Gert Bernstein et al.   SCHIZOPHRENIA RESEARCH

Excitatory/inhibitory imbalance in autism spectrum disorders: Implications for interventions and therapeutics

(2015) Genoveva Uzunova et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

ErbB4 in Laminated Brain Structures: A Neurodevelopmental Approach to Schizophrenia

(2015) Carlos G. Perez-Garcia   Frontiers in Cellular Neuroscience

Targeting Glia with N-Acetylcysteine Modulates Brain Glutamate and Behaviors Relevant to Neurodevelopmental Disorders in C57BL/6J Mice

(2015) Alice M. S. Durieux et al.   Frontiers in Behavioral Neuroscience

Psychiatric Disorders From Childhood to Adulthood in 22q11.2 Deletion Syndrome: Results From the International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome

(2014) Maude Schneider et al.   AMERICAN JOURNAL OF PSYCHIATRY

Prefrontal cortical minicolumn: from executive control to disrupted cognitive processing

(2014) Ioan Opris et al.   BRAIN

De novo mutations in schizophrenia implicate synaptic networks

(2014) Menachem Fromer et al.   NATURE

Maternal immune activation and abnormal brain development across CNS disorders

(2014) Irene Knuesel et al.   Nature Reviews Neurology

The RDoC framework: facilitating transition from ICD/DSM to dimensional approaches that integrate neuroscience and psychopathology

(2014) Bruce N. Cuthbert   World Psychiatry

Meta-analysis of SHANK Mutations in Autism Spectrum Disorders: A Gradient of Severity in Cognitive Impairments

(2014) Claire S. Leblond et al.   PLoS Genetics

A Comprehensive Assessment of Parental Age and Psychiatric Disorders

(2014) John J. McGrath et al.   JAMA Psychiatry

Revisiting the Relationship Between Autism and Schizophrenia: Toward an Integrated Neurobiology

(2013) Nina de Lacy et al.   Annual Review of Clinical Psychology

Targeting Glia Cells: Novel Perspectives for the Treatment of Neuropsychiatric Diseases

(2013) B. Benedetto et al.   Current Neuropharmacology

Is the mTOR-signalling cascade disrupted in Schizophrenia?

(2013) Anand Gururajan et al.   JOURNAL OF NEUROCHEMISTRY

mTOR complexes in neurodevelopmental and neuropsychiatric disorders

(2013) Mauro Costa-Mattioli et al.   NATURE NEUROSCIENCE

NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease

(2013) Pierre Paoletti et al.   NATURE REVIEWS NEUROSCIENCE

Altered Social Behaviours in Neurexin 1α Knockout Mice Resemble Core Symptoms in Neurodevelopmental Disorders

(2013) Hannah Mary Grayton et al.   PLoS One

Reversing autism by targeting downstream mTOR signaling

(2013) Hansen Wang et al.   Frontiers in Cellular Neuroscience

NMDA hypofunction as a convergence point for progression and symptoms of schizophrenia

(2013) Melissa A. Snyder et al.   Frontiers in Cellular Neuroscience

Multiple Roles for Mammalian Target of Rapamycin Signaling in Both Glutamatergic and GABAergic Synaptic Transmission

(2012) M. C. Weston et al.   JOURNAL OF NEUROSCIENCE

Dendritic spine pathology in schizophrenia

(2012) J.R. Glausier et al.   NEUROSCIENCE

Negative Allosteric Modulation of the mGluR5 Receptor Reduces Repetitive Behaviors and Rescues Social Deficits in Mouse Models of Autism

(2012) J. L. Silverman et al.   Science Translational Medicine

Synapse dysfunction in autism: a molecular medicine approach to drug discovery in neurodevelopmental disorders

(2012) Will Spooren et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

GABAergic Circuit Dysfunctions in Neurodevelopmental Disorders

(2012) Bidisha Chattopadhyaya et al.   Frontiers in Psychiatry

The role of immune dysfunction in the pathophysiology of autism

(2011) Charity Onore et al.   BRAIN BEHAVIOR AND IMMUNITY

An autism-associated point mutation in the neuroligin cytoplasmic tail selectively impairs AMPA receptor-mediated synaptic transmission in hippocampus

(2011) Mark R Etherton et al.   EMBO JOURNAL

Truncating mutations in NRXN2 and NRXN1 in autism spectrum disorders and schizophrenia

(2011) Julie Gauthier et al.   HUMAN GENETICS

Transcriptomic analysis of autistic brain reveals convergent molecular pathology

(2011) Irina Voineagu et al.   NATURE

The role of neurexins in schizophrenia and autistic spectrum disorder

(2011) A.C. Reichelt et al.   NEUROPHARMACOLOGY

DISC1-binding proteins in neural development, signalling and schizophrenia

(2011) Nicholas J. Bradshaw et al.   NEUROPHARMACOLOGY

Rare mutations in N-methyl-D-aspartate glutamate receptors in autism spectrum disorders and schizophrenia

(2011) J Tarabeux et al.   Translational Psychiatry

Is schizophrenia on the autism spectrum?

(2010) Bryan H. King et al.   BRAIN RESEARCH

Neuregulin 1–erbB4 pathway in schizophrenia: From genes to an interactome

(2010) Anamika Banerjee et al.   BRAIN RESEARCH BULLETIN

The chandelier neuron in schizophrenia

(2010) David A. Lewis   Developmental Neurobiology

Decreased GABAB receptors in the cingulate cortex and fusiform gyrus in Autism

(2010) Adrian L. Oblak et al.   JOURNAL OF NEUROCHEMISTRY

Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders

(2009) Jeffrey J. Hutsler et al.   BRAIN RESEARCH

A Neuroligin-4 Missense Mutation Associated with Autism Impairs Neuroligin-4 Folding and Endoplasmic Reticulum Export

(2009) C. Zhang et al.   JOURNAL OF NEUROSCIENCE

The Neurodevelopmental Hypothesis of Schizophrenia, Revisited

(2009) S. H. Fatemi et al.   SCHIZOPHRENIA BULLETIN

Social cognition in schizophrenia: a review of face processing

(2008) K. Marwick et al.   BRITISH MEDICAL BULLETIN

Autism Spectrum Disorders and Childhood-Onset Schizophrenia: Clinical and Biological Contributions to a Relation Revisited

(2008) Judith Rapoport et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

GABA Neurons and the Mechanisms of Network Oscillations: Implications for Understanding Cortical Dysfunction in Schizophrenia

(2008) G. Gonzalez-Burgos et al.   SCHIZOPHRENIA BULLETIN

Altered excitatory-inhibitory balance in the NMDA-hypofunction model of schizophrenia

(2008) Colin Kehrer   Frontiers in Molecular Neuroscience