Redirected Primary Human Chimeric Antigen Receptor Natural Killer Cells As an “Off-the-Shelf Immunotherapy” for Improvement in Cancer Treatment
出版年份 2017 全文链接
标题
Redirected Primary Human Chimeric Antigen Receptor Natural Killer Cells As an “Off-the-Shelf Immunotherapy” for Improvement in Cancer Treatment
作者
关键词
-
出版物
Frontiers in Immunology
Volume 8, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2017-06-09
DOI
10.3389/fimmu.2017.00654
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Molecular Pathways: Targeting CD96 and TIGIT for Cancer Immunotherapy
- (2016) S. J. Blake et al. CLINICAL CANCER RESEARCH
- Improving efficacy of cancer immunotherapy by genetic modification of natural killer cells
- (2016) Rachel A. Burga et al. CYTOTHERAPY
- Human NK cells: From surface receptors to clinical applications
- (2016) Lorenzo Moretta et al. IMMUNOLOGY LETTERS
- Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape
- (2016) Meenakshi Hegde et al. JOURNAL OF CLINICAL INVESTIGATION
- Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukemia
- (2016) Rizwan Romee et al. Science Translational Medicine
- Natural Killer Cells for Therapy of Leukemia
- (2016) Garnet Suck et al. TRANSFUSION MEDICINE AND HEMOTHERAPY
- Characterization of IFNγ-producing natural killer cells induced by cytomegalovirus reactivation after haploidentical hematopoietic stem cell transplantation
- (2016) Fengyan Jin et al. Oncotarget
- A combinational therapy of EGFR-CAR NK cells and oncolytic herpes simplex virus 1 for breast cancer brain metastases
- (2016) Xilin Chen et al. Oncotarget
- Targeting Ewing sarcoma with activated and GD2-specific chimeric antigen receptor-engineered human NK cells induces upregulation of immune-inhibitory HLA-G
- (2016) Sareetha Kailayangiri et al. OncoImmunology
- NK-92: an ‘off-the-shelf therapeutic’ for adoptive natural killer cell-based cancer immunotherapy
- (2015) Garnet Suck et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Cancer gene therapy with T cell receptors and chimeric antigen receptors
- (2015) Hans J Stauss et al. CURRENT OPINION IN PHARMACOLOGY
- Differential activation of cord blood and peripheral blood natural killer cells by cytokines
- (2015) Rehab Alnabhan et al. CYTOTHERAPY
- Cord blood: a promising source of allogeneic natural killer cells for immunotherapy
- (2015) Hila Shaim et al. CYTOTHERAPY
- DAP12-Based Activating Chimeric Antigen Receptor for NK Cell Tumor Immunotherapy
- (2015) Katrin Töpfer et al. JOURNAL OF IMMUNOLOGY
- Engineering NK Cells Modified With an EGFRvIII-specific Chimeric Antigen Receptor to Overexpress CXCR4 Improves Immunotherapy of CXCL12/SDF-1α-secreting Glioblastoma
- (2015) Nadja Müller et al. JOURNAL OF IMMUNOTHERAPY
- Efficient generation of gene-modified human natural killer cells via alpharetroviral vectors
- (2015) Julia D. Suerth et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Remote control of therapeutic T cells through a small molecule-gated chimeric receptor
- (2015) C.-Y. Wu et al. SCIENCE
- Advantages and applications of CAR-expressing natural killer cells
- (2015) Wolfgang Glienke et al. Frontiers in Pharmacology
- The Application of Natural Killer Cell Immunotherapy for the Treatment of Cancer
- (2015) Katayoun Rezvani et al. Frontiers in Immunology
- Dual targeting of glioblastoma with chimeric antigen receptor-engineered natural killer cells overcomes heterogeneity of target antigen expression and enhances antitumor activity and survival
- (2015) Sabrina Genßler et al. OncoImmunology
- Advances in clinical NK cell studies: Donor selection, manufacturing and quality control
- (2015) U. Koehl et al. OncoImmunology
- CAR-Engineered NK Cells Targeting Wild-Type EGFR and EGFRvIII Enhance Killing of Glioblastoma and Patient-Derived Glioblastoma Stem Cells
- (2015) Jianfeng Han et al. Scientific Reports
- Acute GVHD in patients receiving IL-15/4-1BBL activated NK cells following T-cell-depleted stem cell transplantation
- (2014) N. N. Shah et al. BLOOD
- Antibody-modified T cells: CARs take the front seat for hematologic malignancies
- (2014) M. V. Maus et al. BLOOD
- Allogeneic chimeric antigen receptor-modified cells for adoptive cell therapy of cancer
- (2014) Assaf Marcus et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Natural Killer Cell Functional Activity After 4-1BB Costimulation
- (2014) Shadi sadat Navabi et al. INFLAMMATION
- Enhanced Cytotoxicity of Natural Killer Cells following the Acquisition of Chimeric Antigen Receptors through Trogocytosis
- (2014) Fu-Nan Cho et al. PLoS One
- Targeting CD20+ Aggressive B-cell Non-Hodgkin Lymphoma by Anti-CD20 CAR mRNA-Modified Expanded Natural Killer Cells In Vitro and in NSG Mice
- (2014) Y. Chu et al. Cancer Immunology Research
- Improving the safety of cell therapy products by suicide gene transfer
- (2014) Benjamin S. Jones et al. Frontiers in Pharmacology
- Are natural killer cells superior CAR drivers?
- (2014) Hans Klingemann OncoImmunology
- Controlling Natural Killer Cell Responses: Integration of Signals for Activation and Inhibition
- (2013) Eric O. Long et al. Annual Review of Immunology
- A Chimeric Receptor with NKG2D Specificity Enhances Natural Killer Cell Activation and Killing of Tumor Cells
- (2013) Y.-H. Chang et al. CANCER RESEARCH
- DNAM-1 control of natural killer cells functions through nectin and nectin-like proteins
- (2013) Lucas Ferrari de Andrade et al. IMMUNOLOGY AND CELL BIOLOGY
- CS1-specific chimeric antigen receptor (CAR)-engineered natural killer cells enhance in vitro and in vivo antitumor activity against human multiple myeloma
- (2013) J Chu et al. LEUKEMIA
- Treatment of Metastatic Renal Cell Carcinoma With CAIX CAR-engineered T cells: Clinical Evaluation and Management of On-target Toxicity
- (2013) Cor HJ Lamers et al. MOLECULAR THERAPY
- In Vivo Proof of Concept of Adoptive Immunotherapy for Hepatocellular Carcinoma Using Allogeneic Suicide Gene-modified Killer Cells
- (2013) Céline Leboeuf et al. MOLECULAR THERAPY
- Antigen Presenting Cell-Mediated Expansion of Human Umbilical Cord Blood Yields Log-Scale Expansion of Natural Killer Cells with Anti-Myeloma Activity
- (2013) Nina Shah et al. PLoS One
- A clinically adaptable method to enhance the cytotoxicity of natural killer cells against B-cell malignancies
- (2012) Noriko Shimasaki et al. CYTOTHERAPY
- The Adaptor Protein Crk Controls Activation and Inhibition of Natural Killer Cells
- (2012) Dongfang Liu et al. IMMUNITY
- Bispecific and Trispecific Killer Cell Engagers Directly Activate Human NK Cells through CD16 Signaling and Induce Cytotoxicity and Cytokine Production
- (2012) M. K. Gleason et al. MOLECULAR CANCER THERAPEUTICS
- Combinatorial antigen recognition with balanced signaling promotes selective tumor eradication by engineered T cells
- (2012) Christopher C Kloss et al. NATURE BIOTECHNOLOGY
- Inhibitory signaling blocks activating receptor clustering and induces cytoskeletal retraction in natural killer cells
- (2011) Thushara P. Abeyweera et al. JOURNAL OF CELL BIOLOGY
- Homeostatic proliferation generates long-lived natural killer cells that respond against viral infection
- (2011) Joseph C. Sun et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Activating Signals Dominate Inhibitory Signals in CD137L/IL-15 Activated Natural Killer Cells
- (2011) Hua Zhang et al. JOURNAL OF IMMUNOTHERAPY
- Improving Adoptive T Cell Therapy by Targeting and Controlling IL-12 Expression to the Tumor Environment
- (2011) Ling Zhang et al. MOLECULAR THERAPY
- Inducible Apoptosis as a Safety Switch for Adoptive Cell Therapy
- (2011) Antonio Di Stasi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Control of Immunity by the TNFR-Related Molecule OX40 (CD134)
- (2010) Michael Croft Annual Review of Immunology
- IL-2-activated haploidentical NK cells restore NKG2D-mediated NK-cell cytotoxicity in neuroblastoma patients by scavenging of plasma MICA
- (2010) Stephan Kloess et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Treatment of Chronic Lymphocytic Leukemia With Genetically Targeted Autologous T Cells: Case Report of an Unforeseen Adverse Event in a Phase I Clinical Trial
- (2010) Renier Brentjens et al. MOLECULAR THERAPY
- Case Report of a Serious Adverse Event Following the Administration of T Cells Transduced With a Chimeric Antigen Receptor Recognizing ERBB2
- (2010) Richard A Morgan et al. MOLECULAR THERAPY
- Regulation of human NK-cell cytokine and chemokine production by target cell recognition
- (2009) C. Fauriat et al. BLOOD
- Expression of chimeric antigen receptors in natural killer cells with a regulatory-compliant non-viral method
- (2009) L Li et al. CANCER GENE THERAPY
- Expansion of Highly Cytotoxic Human Natural Killer Cells for Cancer Cell Therapy
- (2009) H. Fujisaki et al. CANCER RESEARCH
- 2B4 (CD244) Signaling by Recombinant Antigen-specific Chimeric Receptors Costimulates Natural Killer Cell Activation to Leukemia and Neuroblastoma Cells
- (2009) B. Altvater et al. CLINICAL CANCER RESEARCH
- Chimeric Receptors Containing CD137 Signal Transduction Domains Mediate Enhanced Survival of T Cells and Increased Antileukemic Efficacy In Vivo
- (2009) Michael C. Milone et al. MOLECULAR THERAPY
- Natural killer cell immunotherapy for cancer: a new hope
- (2008) S. Srivastava et al. CYTOTHERAPY
- Inhibitory Receptor Signaling via Tyrosine Phosphorylation of the Adaptor Crk
- (2008) Mary E. Peterson et al. IMMUNITY
- Phenotypic and Functional Heterogeneity of Natural Killer Cells from Umbilical Cord Blood Mononuclear Cells
- (2008) Yan-Ying Fan et al. IMMUNOLOGICAL INVESTIGATIONS
- Negative signaling by inhibitory receptors: the NK cell paradigm
- (2008) Eric O. Long IMMUNOLOGICAL REVIEWS
- Natural Killer Cells in Innate Immunity and Cancer
- (2008) Brian Becknell et al. JOURNAL OF IMMUNOTHERAPY
- Up on the tightrope: natural killer cell activation and inhibition
- (2008) Lewis L Lanier NATURE IMMUNOLOGY
- Functions of natural killer cells
- (2008) Eric Vivier et al. NATURE IMMUNOLOGY
- Engineering antigen-specific primary human NK cells against HER-2 positive carcinomas
- (2008) A. Kruschinski et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now