Potential Protective Effects of Ursolic Acid against Gamma Irradiation-Induced Damage Are Mediated through the Modulation of Diverse Inflammatory Mediators

Ursolic acid from apple pomace and traditional plants: A valuable triterpenoid with functional properties

(2017) Simone Tasca Cargnin et al.   FOOD CHEMISTRY

A COMPARISON OF REMEDIATION AFTER THE CHERNOBYL AND FUKUSHIMA DAIICHI ACCIDENTS

(2017) Sergey Fesenko et al.   RADIATION PROTECTION DOSIMETRY

Temporal variation of cesium isotope concentrations and atom ratios in zooplankton in the Pacific off the east coast of Japan

(2017) Takahito Ikenoue et al.   Scientific Reports

Ursolic acid-loaded chitosan nanoparticles induce potent anti-angiogenesis in tumor

(2016) Hua Jin et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

IinQ attenuates systemic inflammatory responses via selectively impairing the Myddosome complex formation upon TLR4 ligation

(2016) Kidong Kang et al.   BIOCHEMICAL PHARMACOLOGY

Effect of Loquat Leaf Extract on Muscle Strength, Muscle Mass, and Muscle Function in Healthy Adults: A Randomized, Double-Blinded, and Placebo-Controlled Trial

(2016) Young Hye Cho et al.   Evidence-based Complementary and Alternative Medicine

Radioprotective effect of green tea and grape seed extracts mixture on gamma irradiation induced immune suppression in male albino rats

(2016) Wael El-Desouky et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Modulation of gamma-irradiation and carbon tetrachloride induced oxidative stress in the brain of female rats by flaxseed oil

(2016) Amel F.M. Ismail et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Renoprotective effects of ursolic acid on ischemia/reperfusion-induced acute kidney injury through oxidative stress, inflammation and the inhibition of STAT3 and NF-κB activities

(2016) Jun Peng et al.   Molecular Medicine Reports

Potential use of nanocarriers with pentacyclic triterpenes in cancer treatments

(2016) Karina Valdés et al.   Nanomedicine

Oxidative Damage and Inflammation Biomarkers

(2016) Gerald M. Haase et al.   OTOLOGY & NEUROTOLOGY

Synthetic antimicrobial and LPS-neutralising peptides suppress inflammatory and immune responses in skin cells and promote keratinocyte migration

(2016) Anja Pfalzgraff et al.   Scientific Reports

NF-κB in cancer therapy

(2015) Feng Li et al.   ARCHIVES OF TOXICOLOGY

Analysis of the intricate relationship between chronic inflammation and cancer

(2015) Edna Zhi Pei Chai et al.   BIOCHEMICAL JOURNAL

Naringin inhibits gamma radiation-induced oxidative DNA damage and inflammation, by modulating p53 and NF-κB signaling pathways in murine splenocytes

(2015) K. Manna et al.   FREE RADICAL RESEARCH

A structure–activity relationship study on antiosteoclastogenesis effect of triterpenoids from the leaves of loquat (Eriobotrya japonica)

(2015) Hui Tan et al.   PHYTOMEDICINE

A Phase I Trial to Evaluate the Multiple-Dose Safety and Antitumor Activity of Ursolic Acid Liposomes in Subjects with Advanced Solid Tumors

(2015) Zhengzi Qian et al.   Biomed Research International

New Approaches to Radiation Protection

(2015) Eliot M. Rosen et al.   Frontiers in Oncology

Des-Aspartate-Angiotensin I Attenuates Mortality of Mice Exposed to Gamma Radiation via a Novel Mechanism of Action

(2015) Hong Wang et al.   PLoS One

Synthesis and Evaluation of Novel Triterpene Analogues of Ursolic Acid as Potential Antidiabetic Agent

(2015) Panpan Wu et al.   PLoS One

Colloidal Drug Formulations Can Explain “Bell-Shaped” Concentration–Response Curves

(2014) Shawn C. Owen et al.   ACS Chemical Biology

Radioprotective effect ofRapana thomasianahemocyanin in gamma induced acute radiation syndrome

(2014) Ivan Kindekov et al.   BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT

Role of Ferulic Acid in the Amelioration of Ionizing Radiation Induced Inflammation: A Murine Model

(2014) Ujjal Das et al.   PLoS One

Ursolic acid differentially modulates apoptosis in skin melanoma and retinal pigment epithelial cells exposed to UV–VIS broadband radiation

(2013) Yuan-Hao Lee et al.   APOPTOSIS

Ursolic acid in cancer prevention and treatment: Molecular targets, pharmacokinetics and clinical studies

(2013) Muthu K. Shanmugam et al.   BIOCHEMICAL PHARMACOLOGY

Ursolic acid inhibits tumor angiogenesis and induces apoptosis through mitochondrial-dependent pathway in Ehrlich ascites carcinoma tumor

(2013) Sarita Saraswati et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Radioprotectors - the Evergreen Topic

(2013) Vesna S. Kuntić et al.   CHEMISTRY & BIODIVERSITY

A phase I pharmacokinetic study of ursolic acid nanoliposomes in healthy volunteers and patients with advanced solid tumors

(2013) Zhao Yan et al.   International Journal of Nanomedicine

Infusion of Trx-1-Overexpressing hucMSC Prolongs the Survival of Acutely Irradiated NOD/SCID Mice by Decreasing Excessive Inflammatory Injury

(2013) JiangWei Hu et al.   PLoS One

HIV-TAT mediated protein transduction of Cu/Zn-superoxide dismutase-1 (SOD1) protects skin cells from ionizing radiation

(2013) Qing Gu et al.   Radiation Oncology

Evaluation of toxicity and single-dose pharmacokinetics of intravenous ursolic acid liposomes in healthy adult volunteers and patients with advanced solid tumors

(2012) Xian-Huo Wang et al.   Expert Opinion on Drug Metabolism & Toxicology

Epicatechin ameliorates ionising radiation-induced oxidative stress in mouse liver

(2012) Mahuya Sinha et al.   FREE RADICAL RESEARCH

Acute Gastrointestinal Syndrome in High-Dose Irradiated Mice

(2012) Catherine Booth et al.   HEALTH PHYSICS

Modulation of Photochemical Damage in Normal and Malignant Cells by Naturally Occurring Compounds†

(2012) Yuan-Hao Lee et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Ursolic Acid Inhibits the Initiation, Progression of Prostate Cancer and Prolongs the Survival of TRAMP Mice by Modulating Pro-Inflammatory Pathways

(2012) Muthu K. Shanmugam et al.   PLoS One

Potent Anti-Inflammatory Activity of Ursolic Acid, a Triterpenoid Antioxidant, Is Mediated through Suppression of NF-κB, AP-1 and NF-AT

(2012) Rahul Checker et al.   PLoS One

Multifaceted link between cancer and inflammation

(2011) Gautam Sethi et al.   BIOSCIENCE REPORTS

Inhibition of CXCR4/CXCL12 signaling axis by ursolic acid leads to suppression of metastasis in transgenic adenocarcinoma of mouse prostate model

(2011) Muthu K. Shanmugam et al.   INTERNATIONAL JOURNAL OF CANCER

Clinically useful anticancer, antitumor, and antiwrinkle agent, ursolic acid and related derivatives as medicinally important natural product

(2011) Nighat Sultana   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Ursolic acid inhibits multiple cell survival pathways leading to suppression of growth of prostate cancer xenograft in nude mice

(2011) Muthu K. Shanmugam et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Radioprotection by α-asarone: Prevention of genotoxicity and hematopoietic injury in mammalian organism

(2011) Divyasree Sandeep et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Electrical behavior of stored erythrocytes after exposure to gamma radiation and the role of α-lipoic acid as radioprotector

(2010) Nabila S. Selim et al.   APPLIED RADIATION AND ISOTOPES

Targeting transcription factor NF-κB to overcome chemoresistance and radioresistance in cancer therapy

(2010) Feng Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Potential Relevance of Bell-Shaped and U-Shaped Dose-Responses for the Therapeutic Targeting of Angiogenesis in Cancer

(2010) Andrew R. Reynolds   Dose-Response

Protection of DNA and membrane from γ-radiation induced damage by the extract of Acorus calamus Linn.: An in vitro study

(2010) Divyasree Sandeep et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Protection from lethal and sub-lethal whole body exposures of mice to γ-radiation by Acorus calamus L.: Studies on tissue antioxidant status and cellular DNA damage

(2010) Divyasree Sandeep et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

1,25-Dihydroxyvitamin D3 modulates effects of ionizing radiation (IR) on human keratinocytes: In vitro analysis of cell viability/proliferation, DNA-damage and -repair

(2010) Lea Trémezaygues et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Animal Models for Medical Countermeasures to Radiation Exposure

(2010) Jacqueline P. Williams et al.   RADIATION RESEARCH

Podophyllum hexandrum-Mediated Survival Protection and Restoration of Other Cellular Injuries in Lethally Irradiated Mice

(2009) Sanghmitra Sankhwar et al.   Evidence-based Complementary and Alternative Medicine

Potential pharmacological control of the NF-κB pathway

(2009) Gautam Sethi et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Effect of ursolic acid, a triterpenoid antioxidant, on ultraviolet-B radiation-induced cytotoxicity, lipid peroxidation and DNA damage in human lymphocytes

(2008) S. Ramachandran et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Nuclear Factor-κB Activation: From Bench to Bedside

(2008) Gautam Sethi et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Whole body protection against lethal ionizing radiation in mice by REC-2001: A semi-purified fraction of Podophyllum hexandrum

(2007) M. Lata et al.   PHYTOMEDICINE