Synthesis and Evaluation of Novel Triterpene Analogues of Ursolic Acid as Potential Antidiabetic Agent

UP12, a novel ursolic acid derivative with potential for targeting multiple signaling pathways in hepatocellular carcinoma

(2015) Haiyan Dong et al.   BIOCHEMICAL PHARMACOLOGY

The mechanism of action of ursolic acid as insulin secretagogue and insulinomimetic is mediated by cross-talk between calcium and kinases to regulate glucose balance

(2015) Allisson Jhonatan Gomes Castro et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Synthesis, in vitro antimicrobial and cytotoxic activities of new carbazole derivatives of ursolic acid

(2015) Wen Gu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Structure–activity relationships of 3-O-β-chacotriosyl ursolic acid derivatives as novel H5N1 entry inhibitors

(2015) Gaopeng Song et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis and in vitro evaluation of novel ursolic acid derivatives as potential anticancer agents

(2015) Shi-Xian Hua et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A hydrophilic conjugate approach toward the design and synthesis of ursolic acid derivatives as potential antidiabetic agent

(2015) TianMing Huang et al.   RSC Advances

QSAR-guided semi-synthesis and in vitro validation of antiplasmodial activity in ursolic acid derivatives

(2015) Komal Kalani et al.   RSC Advances

Synergism of ursolic acid derivative US597 with 2-deoxy-D-glucose to preferentially induce tumor cell death by dual-targeting of apoptosis and glycolysis

(2015) Jichuang Wang et al.   Scientific Reports

In vitro and in vivo evaluation of the antidiabetic activity of ursolic acid derivatives

(2014) Pan-Pan Wu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Effects of Ursolic Acid Derivatives on Caco-2 Cells and Their Alleviating Role in Streptozocin-Induced Type 2 Diabetic Rats

(2014) Panpan Wu et al.   MOLECULES

Binding Mode Analyses and Pharmacophore Model Development for Stilbene Derivatives as a Novel and Competitive Class of α-Glucosidase Inhibitors

(2014) Yuno Lee et al.   PLoS One

Synthesis and evaluation of ursolic acid derivatives as potent cytotoxic agents

(2012) Kai-Kai Bai et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of new N-substituted aminoquercitols from naturally available (+)-proto-quercitol and their α-glucosidase inhibitory activity

(2012) Wisuttaya Worawalai et al.   MedChemComm

An Amphiphilic Conjugate Approach toward the Design and Synthesis of Betulinic Acid-Polyphenol Conjugates as Inhibitors of the HIV-1 gp41 Fusion Core Formation

(2011) Yan Liu et al.   ChemMedChem

Antidiabetic activity of some pentacyclic acid triterpenoids, role of PTP–1B: In vitro, in silico, and in vivo approaches

(2011) Juan José Ramírez-Espinosa et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The synthesis of ursolic acid derivatives with cytotoxic activity and the investigation of their preliminary mechanism of action

(2008) Yan-Qiu Meng et al.   BIOORGANIC & MEDICINAL CHEMISTRY