Gene Delivery Approaches for Mesenchymal Stem Cell Therapy: Strategies to Increase Efficiency and Specificity
出版年份 2017 全文链接
标题
Gene Delivery Approaches for Mesenchymal Stem Cell Therapy: Strategies to Increase Efficiency and Specificity
作者
关键词
Mesenchymal stem cells, Viral vectors, Gene delivery, Stem cell applications, CRISPR/Cas, Optogenetics, Pharmacogenomics
出版物
Stem Cell Reviews and Reports
Volume 13, Issue 6, Pages 725-740
出版商
Springer Nature
发表日期
2017-08-16
DOI
10.1007/s12015-017-9760-2
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Pharmacogenomics in pediatric acute lymphoblastic leukemia: promises and limitations
- (2017) Zeina N Al-Mahayri et al. PHARMACOGENOMICS
- Subcellular Optogenetics Enacted by Targeted Nanotransformers of Near-Infrared Light
- (2017) Artem Pliss et al. ACS Photonics
- Development and potential applications of CRISPR-Cas9 genome editing technology in sarcoma
- (2016) Tang Liu et al. CANCER LETTERS
- Stroke Serum Priming Modulates Characteristics of Mesenchymal Stromal Cells by Controlling the Expression miRNA-20a
- (2016) Eun Hee Kim et al. CELL TRANSPLANTATION
- Adenoviral vector encoding soluble Flt-1 engineered human endometrial mesenchymal stem cells effectively regress endometriotic lesions in NOD/SCID mice
- (2016) A R Koippallil Gopalakrishnan et al. GENE THERAPY
- Overexpression of Gremlin1 in Mesenchymal Stem Cells Improves Hindlimb Ischemia in Mice by Enhancing Cell Survival
- (2016) Qiuling Xiang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Shining Light on the Sprout of Life: Optogenetics Applications in Stem Cell Research and Therapy
- (2016) Hadi Mirzapour Delavar et al. JOURNAL OF MEMBRANE BIOLOGY
- Challenges in Determining Genotypes for Pharmacogenetics in Allogeneic Hematopoietic Cell Transplant Recipients
- (2016) Loralie J. Langman et al. JOURNAL OF MOLECULAR DIAGNOSTICS
- Mouse mesenchymal stem cells inhibit high endothelial cell activation and lymphocyte homing to lymph nodes by releasing TIMP-1
- (2016) L Zanotti et al. LEUKEMIA
- High-fidelity CRISPR–Cas9 nucleases with no detectable genome-wide off-target effects
- (2016) Benjamin P. Kleinstiver et al. NATURE
- Lentivirus-mediated PGC-1α overexpression protects against traumatic spinal cord injury in rats
- (2016) Jianzhong Hu et al. NEUROSCIENCE
- Co-overexpression of TGF-β and SOX9 via rAAV gene transfer modulates the metabolic and chondrogenic activities of human bone marrow-derived mesenchymal stem cells
- (2016) Ke Tao et al. Stem Cell Research & Therapy
- Adult Stem Cell Therapy for Stroke: Challenges and Progress
- (2016) Oh Young Bang et al. Journal of Stroke
- Erratum: Corrigendum: Efficient delivery of C/EBP beta gene into human mesenchymal stem cells via polyethylenimine-coated gold nanoparticles enhances adipogenic differentiation
- (2016) Joydeep Das et al. Scientific Reports
- Human mesenchymal stem cells - current trends and future prospective
- (2015) Imran Ullah et al. BIOSCIENCE REPORTS
- Therapeutic Effects of Transplantation of As-MiR-937-Expressing Mesenchymal Stem Cells in Murine Model of Alzheimer's Disease
- (2015) Zhen Liu et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- A novel intranuclear RNA vector system for long-term stem cell modification
- (2015) Y Ikeda et al. GENE THERAPY
- Making Sense of Optogenetics
- (2015) Akash Guru et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Mesenchymal Stem Cell Therapy for the Treatment of Erectile Dysfunction
- (2015) Mohit Khera et al. Journal of Sexual Medicine
- Genetically modified human placenta-derived mesenchymal stem cells with FGF-2 and PDGF-BB enhance neovascularization in a model of hindlimb ischemia
- (2015) TAO YIN et al. Molecular Medicine Reports
- Moving Stem Cells to the Clinic: Potential and Limitations for Brain Repair
- (2015) Julius A. Steinbeck et al. NEURON
- Rationally engineered Cas9 nucleases with improved specificity
- (2015) I. M. Slaymaker et al. SCIENCE
- Mesenchymal stem cells expressing baculovirus-engineered BMP-2 and VEGF enhance posterolateral spine fusion in a rabbit model
- (2015) Tsai-Sheng Fu et al. Spine Journal
- The challenges and promises of allogeneic mesenchymal stem cells for use as a cell-based therapy
- (2015) Jun Zhang et al. Stem Cell Research & Therapy
- Transcription Factor Competition Allows Embryonic Stem Cells to Distinguish Authentic Signals from Noise
- (2015) Cameron Sokolik et al. Cell Systems
- The Anti-Tumor Effects of Adipose Tissue Mesenchymal Stem Cell Transduced with HSV-Tk Gene on U-87-Driven Brain Tumor
- (2015) Suely Maymone de Melo et al. PLoS One
- Dissecting Engineered Cell Types and Enhancing Cell Fate Conversion via CellNet
- (2014) Samantha A. Morris et al. CELL
- Determination of the Chondrogenic Differentiation Processes in Human Bone Marrow-Derived Mesenchymal Stem Cells Genetically Modified to Overexpress Transforming Growth Factor-β via Recombinant Adeno-Associated Viral Vectors
- (2014) Janina Frisch et al. HUMAN GENE THERAPY
- Targeting cells with single vectors using multiple-feature Boolean logic
- (2014) Lief E Fenno et al. NATURE METHODS
- Mesenchymal stem cells: mechanisms and role in bone regeneration
- (2014) Yunhao Qin et al. POSTGRADUATE MEDICAL JOURNAL
- Influence of insulin-like growth factor I overexpression via recombinant adeno-associated vector gene transfer upon the biological activities and differentiation potential of human bone marrow-derived mesenchymal stem cells
- (2014) Janina Frisch et al. Stem Cell Research & Therapy
- Modulation of Stem Cell Differentiation by the Influence of Nanobiomaterials/ Carriers
- (2014) Kiran Bokara et al. Current Stem Cell Research & Therapy
- One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering
- (2013) Haoyi Wang et al. CELL
- Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity
- (2013) F. Ann Ran et al. CELL
- Biallelic genome modification in F0Xenopus tropicalisembryos using the CRISPR/Cas system
- (2013) Ira L. Blitz et al. GENESIS
- Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases
- (2013) S. W. Cho et al. GENOME RESEARCH
- High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity
- (2013) Vikram Pattanayak et al. NATURE BIOTECHNOLOGY
- Tumorigenicity as a clinical hurdle for pluripotent stem cell therapies
- (2013) Andrew S Lee et al. NATURE MEDICINE
- Randomized dose-finding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancer
- (2013) Jeong Heo et al. NATURE MEDICINE
- Genome engineering using the CRISPR-Cas9 system
- (2013) F Ann Ran et al. Nature Protocols
- Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells
- (2013) Yingsha Zhang et al. NEURON
- Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease system
- (2013) Li-En Jao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lentiviral Hematopoietic Stem Cell Gene Therapy in Patients with Wiskott-Aldrich Syndrome
- (2013) A. Aiuti et al. SCIENCE
- Lentiviral Hematopoietic Stem Cell Gene Therapy Benefits Metachromatic Leukodystrophy
- (2013) A. Biffi et al. SCIENCE
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- Spinal Cord Explants Use Carbon Nanotube Interfaces To Enhance Neurite Outgrowth and To Fortify Synaptic Inputs
- (2012) Alessandra Fabbro et al. ACS Nano
- Co-delivery of SOX9 genes and anti-Cbfa-1 siRNA coated onto PLGA nanoparticles for chondrogenesis of human MSCs
- (2012) Su Yeon Jeon et al. BIOMATERIALS
- Serum tolerance and endosomal escape capacity of histidine-modified pDNA-loaded complexes based on polyamidoamine dendrimer derivatives
- (2012) Yuting Wen et al. BIOMATERIALS
- Induction Therapy With Autologous Mesenchymal Stem Cells in Living-Related Kidney Transplants
- (2012) Jianming Tan et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Efficacy of mesoporous silica nanoparticles in delivering BMP-2 plasmid DNA forin vitroosteogenic stimulation of mesenchymal stem cells
- (2012) Tae-Hyun Kim et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- Therapeutic potential of mesenchymal stem cells overexpressing human forkhead box A2 gene in the regeneration of damaged liver tissues
- (2012) Jong-Woo Cho et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- Adenoviral Transduction of Mesenchymal Stem Cells: In Vitro Responses and In Vivo Immune Responses after Cell Transplantation
- (2012) Oliver Treacy et al. PLoS One
- Adenoviral Vectors Stimulate Glucagon Transcription in Human Mesenchymal Stem Cells Expressing Pancreatic Transcription Factors
- (2012) Arnaud Zaldumbide et al. PLoS One
- SOX9 gene transfer via safe, stable, replication-defective recombinant adeno-associated virus vectors as a novel, powerful tool to enhance the chondrogenic potential of human mesenchymal stem cells
- (2012) Jagadeesh K Venkatesan et al. Stem Cell Research & Therapy
- Orthopaedic gene therapy using recombinant adeno-associated virus vectors
- (2011) J. Ke et al. ARCHIVES OF ORAL BIOLOGY
- A graphene-based platform for induced pluripotent stem cells culture and differentiation
- (2011) G.-Y. Chen et al. BIOMATERIALS
- Magselectofection: an integrated method of nanomagnetic separation and genetic modification of target cells
- (2011) Y. Sanchez-Antequera et al. BLOOD
- Molecular targeting of malignant glioma cells with an EphA2-specific immunotoxin delivered by human bone marrow-derived mesenchymal stem cells
- (2011) Xin-lin Sun et al. CANCER LETTERS
- Human Embryonic Stem Cell-Derived Mesenchymal Stem Cells as Cellular Delivery Vehicles for Prodrug Gene Therapy of Glioblastoma
- (2011) Xiao Ying Bak et al. HUMAN GENE THERAPY
- Gene Therapy of Intracranial Glioma Using Interleukin 12–Secreting Human Umbilical Cord Blood–Derived Mesenchymal Stem Cells
- (2011) Chung Heon Ryu et al. HUMAN GENE THERAPY
- Carbon Nanotube Scaffolds Tune Synaptic Strength in Cultured Neural Circuits: Novel Frontiers in Nanomaterial-Tissue Interactions
- (2011) G. Cellot et al. JOURNAL OF NEUROSCIENCE
- Human but not murine multipotent mesenchymal stromal cells exhibit broad-spectrum antimicrobial effector function mediated by indoleamine 2,3-dioxygenase
- (2011) R Meisel et al. LEUKEMIA
- Glioma Gene Therapy Using Induced Pluripotent Stem Cell Derived Neural Stem Cells
- (2011) Esther Xingwei Lee et al. MOLECULAR PHARMACEUTICS
- Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans
- (2011) Caroline J. Breitbach et al. NATURE
- The immunomodulatory properties of mesenchymal stem cells
- (2011) Ilaria Marigo et al. Seminars in Immunopathology
- Carbon Nanotube Monolayer Cues for Osteogenesis of Mesenchymal Stem Cells
- (2011) Ku Youn Baik et al. Small
- Electroporation-Mediated Transfer of SOX Trio Genes (SOX-5, SOX-6, and SOX-9) to Enhance the Chondrogenesis of Mesenchymal Stem Cells
- (2011) Hye-Joung Kim et al. STEM CELLS AND DEVELOPMENT
- Lentiviral vector mediated modification of mesenchymal stem cells & enhanced survival in an in vitro model of ischaemia
- (2011) Lisa McGinley et al. Stem Cell Research & Therapy
- Enhanced Gene Delivery and siRNA Silencing by Gold Nanoparticles Coated with Charge-Reversal Polyelectrolyte
- (2010) Shutao Guo et al. ACS Nano
- Cotransplantation of Mesenchymal Stem Cells Might Prevent Death from Graft-versus-Host Disease (GVHD) without Abrogating Graft-versus-Tumor Effects after HLA-Mismatched Allogeneic Transplantation following Nonmyeloablative Conditioning
- (2010) Frédéric Baron et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Hematopoietic Stem Cell Transplantation and Hematopoietic Stem Cell Gene Therapy in X-Linked Adrenoleukodystrophy
- (2010) Nathalie Cartier et al. BRAIN PATHOLOGY
- Baculovirus-transduced bone marrow mesenchymal stem cells for systemic cancer therapy
- (2010) X Y Bak et al. CANCER GENE THERAPY
- Incorporation of carboxylation multiwalled carbon nanotubes into biodegradable poly(lactic-co-glycolic acid) for bone tissue engineering
- (2010) Cuilin Lin et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Mesenchymal stromal cells inhibit graft-versus-host disease of mice in a dose-dependent manner
- (2010) Sun-Young Joo et al. CYTOTHERAPY
- High-Efficiency Transduction of Fibroblasts and Mesenchymal Stem Cells by Tyrosine-Mutant AAV2 Vectors for Their Potential Use in Cellular Therapy
- (2010) Mengxin Li et al. HUMAN GENE THERAPY
- Bone formation on carbon nanotube composite
- (2010) Mrinal Bhattacharya et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- An hydrophobically modified arginine peptide vector system effectively delivers DNA into human mesenchymal stem cells and maintains transgene expression with differentiation
- (2010) Na Young Kim et al. JOURNAL OF GENE MEDICINE
- Enhancing trophic support of mesenchymal stem cells by ex vivo treatment with trophic factors
- (2010) Yun Jung Choi et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia
- (2010) Marina Cavazzana-Calvo et al. NATURE
- Efficacy of Gene Therapy for X-Linked Severe Combined Immunodeficiency
- (2010) Salima Hacein-Bey-Abina et al. NEW ENGLAND JOURNAL OF MEDICINE
- Human stem cells expressing novel TSP-1 variant have anti-angiogenic effect on brain tumors
- (2010) M van Eekelen et al. ONCOGENE
- An Inducible Caspase 9 Suicide Gene to Improve the Safety of Mesenchymal Stromal Cell Therapies
- (2010) Carlos Almeida Ramos et al. STEM CELLS
- Nontoxic Genetic Engineering of Mesenchymal Stem Cells Using Serum-Compatible Pullulan-Spermine/DNA Anioplexes
- (2010) Devang K. Thakor et al. TISSUE ENGINEERING PART C-METHODS
- Novel Magnetic Hydroxyapatite Nanoparticles as Non-Viral Vectors for the Glial Cell Line-Derived Neurotrophic Factor Gene
- (2009) Hsi-Chin Wu et al. ADVANCED FUNCTIONAL MATERIALS
- Efficacy of Bone Marrow-Derived Mesenchymal Stem Cells in the Treatment of Sclerodermatous Chronic Graft-versus-Host Disease: Clinical Report
- (2009) Hong Zhou et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Mesenchymal stem cells protect NOD mice from diabetes by inducing regulatory T cells
- (2009) A. M. Madec et al. DIABETOLOGIA
- Ethical Issues in Stem Cell Research
- (2009) Bernard Lo et al. ENDOCRINE REVIEWS
- Progress and prospects: immune responses to viral vectors
- (2009) S Nayak et al. GENE THERAPY
- Transient Transfection Methods for Clinical Adeno-Associated Viral Vector Production
- (2009) J. Fraser Wright HUMAN GENE THERAPY
- High-efficiency Transient Transduction of Human Embryonic Stem Cell–derived Neurons With Baculoviral Vectors
- (2009) Jieming Zeng et al. MOLECULAR THERAPY
- Adipose Tissue–derived Mesenchymal Stem Cells Expressing Prodrug-converting Enzyme Inhibit Human Prostate Tumor Growth
- (2009) Ilaria T Cavarretta et al. MOLECULAR THERAPY
- Forcing cells to change lineages
- (2009) Thomas Graf et al. NATURE
- Gene Therapy for Immunodeficiency Due to Adenosine Deaminase Deficiency
- (2009) Alessandro Aiuti et al. NEW ENGLAND JOURNAL OF MEDICINE
- Xenotransplantation of Human Mesenchymal Stem Cells into Immunocompetent Rats for Calvarial Bone Repair
- (2009) Ching-Kuang Chuang et al. TISSUE ENGINEERING PART A
- Stem cell therapy in acute myocardial infarction: a review of clinical trials
- (2009) Jon C. George Translational Research
- Donor-Derived Brain Tumor Following Neural Stem Cell Transplantation in an Ataxia Telangiectasia Patient
- (2009) Ninette Amariglio et al. PLOS MEDICINE
- The repair of osteochondral defects using baculovirus-mediated gene transfer with de-differentiated chondrocytes in bioreactor culture
- (2008) Huang-Chi Chen et al. BIOMATERIALS
- Management of CMV, HHV-6, HHV-7 and Kaposi-sarcoma herpesvirus (HHV-8) infections in patients with hematological malignancies and after SCT
- (2008) P Ljungman et al. BONE MARROW TRANSPLANTATION
- How Do Mesenchymal Stromal Cells Suppress T Cells?
- (2008) Armand Keating Cell Stem Cell
- Mesenchymal Stem Cell-Mediated Immunosuppression Occurs via Concerted Action of Chemokines and Nitric Oxide
- (2008) Guangwen Ren et al. Cell Stem Cell
- Forced Alignment of Mesenchymal Stem Cells Undergoing Cardiomyogenic Differentiation Affects Functional Integration With Cardiomyocyte Cultures
- (2008) Daniël A. Pijnappels et al. CIRCULATION RESEARCH
- Do Mesenchymal Stromal Cells Transdifferentiate Into Functional Cardiomyocytes?
- (2008) Robert A. Rose et al. CIRCULATION RESEARCH
- Comparison of different commercially available cationic liposome–DNA lipoplexes: Parameters influencing toxicity and transfection efficiency
- (2008) A. Masotti et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Mesenchymal stem cells for graft-versus-host disease: Close encounters with T cells
- (2008) Francesco Dazzi et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Mesenchymal cells recruit and regulate T regulatory cells
- (2008) M DIIANNI EXPERIMENTAL HEMATOLOGY
- Nonviral delivery of siRNA into mesenchymal stem cells by a combination of ultrasound and microbubbles
- (2008) Kentaro Otani et al. JOURNAL OF CONTROLLED RELEASE
- Enhanced thoracic gene delivery by magnetic nanobead-mediated vector
- (2008) Wenzhong Li et al. JOURNAL OF GENE MEDICINE
- Use of a targeted oncolytic poxvirus, JX-594, in patients with refractory primary or metastatic liver cancer: a phase I trial
- (2008) Byeong-Ho Park et al. LANCET ONCOLOGY
- Self-complementary AAV Vectors; Advances and Applications
- (2008) Douglas M McCarty MOLECULAR THERAPY
- High-efficiency DNA injection into a single human mesenchymal stem cell using a nanoneedle and atomic force microscopy
- (2008) Sung-Woong Han et al. Nanomedicine-Nanotechnology Biology and Medicine
- Nonvirally Engineered Porcine Adipose Tissue-Derived Stem Cells: Use in Posterior Spinal Fusion
- (2008) Dima Sheyn et al. STEM CELLS
- Metabolic Flexibility Permits Mesenchymal Stem Cell Survival in an Ischemic Environment
- (2008) Louise A. Mylotte et al. STEM CELLS
- mRNA Transfection of CXCR4-GFP Fusion—Simply Generated by PCR—Results in Efficient Migration of Primary Human Mesenchymal Stem Cells
- (2008) Martin F. Ryser et al. TISSUE ENGINEERING PART C-METHODS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now