标题
Androgen Signaling in Prostate Cancer
作者
关键词
-
出版物
Cold Spring Harbor Perspectives in Medicine
Volume 7, Issue 9, Pages a030452
出版商
Cold Spring Harbor Laboratory
发表日期
2017-04-08
DOI
10.1101/cshperspect.a030452
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Aberrant corticosteroid metabolism in tumor cells enables GR takeover in enzalutamide resistant prostate cancer
- (2017) Jianneng Li et al. eLife
- Prostate Cancer, Version 3.2012 Featured Updates to the NCCN Guidelines
- (2017) James L. Mohler et al. Journal of the National Comprehensive Cancer Network
- Phase I and II therapies targeting the androgen receptor for the treatment of castration resistant prostate cancer
- (2016) Athanasios Dellis et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Stable Intraprostatic Dihydrotestosterone in Healthy Medically Castrate Men Treated With Exogenous Testosterone
- (2016) Arthi Thirumalai et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- HSD3B1 and resistance to androgen-deprivation therapy in prostate cancer: a retrospective, multicohort study
- (2016) Jason W D Hearn et al. LANCET ONCOLOGY
- BET Bromodomain Inhibitors Enhance Efficacy and Disrupt Resistance to AR Antagonists in the Treatment of Prostate Cancer
- (2016) I. A. Asangani et al. MOLECULAR CANCER RESEARCH
- Redirecting abiraterone metabolism to fine-tune prostate cancer anti-androgen therapy
- (2016) Zhenfei Li et al. NATURE
- Regulators of Androgen Action Resource: a one-stop shop for the comprehensive study of androgen receptor action
- (2016) Database-The Journal of Biological Databases and Curation
- Classical and Non-Classical Roles for Pre-Receptor Control of DHT Metabolism in Prostate Cancer Progression
- (2016) Ailin Zhang et al. Hormones & Cancer
- Androgen Receptor Splice Variants Dimerize to Transactivate Target Genes
- (2015) D. Xu et al. CANCER RESEARCH
- Integrative Clinical Genomics of Advanced Prostate Cancer
- (2015) Dan Robinson et al. CELL
- The Molecular Taxonomy of Primary Prostate Cancer
- (2015) Adam Abeshouse et al. CELL
- Clinical Relevance of Androgen Receptor Splice Variants in Castration-Resistant Prostate Cancer
- (2015) Benjamin L. Maughan et al. CURRENT TREATMENT OPTIONS IN ONCOLOGY
- Abiraterone acetate plus prednisone versus placebo plus prednisone in chemotherapy-naive men with metastatic castration-resistant prostate cancer (COU-AA-302): final overall survival analysis of a randomised, double-blind, placebo-controlled phase 3 study
- (2015) Charles J Ryan et al. LANCET ONCOLOGY
- Conversion of abiraterone to D4A drives anti-tumour activity in prostate cancer
- (2015) Zhenfei Li et al. NATURE
- The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis
- (2015) Mark M Pomerantz et al. NATURE GENETICS
- Are androgen receptor variants a substitute for the full-length receptor?
- (2015) Ji Lu et al. Nature Reviews Urology
- Targeting chromatin binding regulation of constitutively active AR variants to overcome prostate cancer resistance to endocrine-based therapies
- (2015) Siu Chiu Chan et al. NUCLEIC ACIDS RESEARCH
- Androgen receptor splice variants activating the full-length receptor in mediating resistance to androgen-directed therapy
- (2015) Bo Cao et al. Oncotarget
- Bufalin Is a Potent Small-Molecule Inhibitor of the Steroid Receptor Coactivators SRC-3 and SRC-1
- (2014) Y. Wang et al. CANCER RESEARCH
- Androgen Receptor Is the Key Transcriptional Mediator of the Tumor Suppressor SPOP in Prostate Cancer
- (2014) C. Geng et al. CANCER RESEARCH
- Hormone Whodunit: Clues for Solving the Case of Intratumor Androgen Production
- (2014) K. E. Knudsen CLINICAL CANCER RESEARCH
- Biologic and clinical significance of androgen receptor variants in castration resistant prostate cancer
- (2014) Kathryn E Ware et al. ENDOCRINE-RELATED CANCER
- Beyond T and DHT - Novel Steroid Derivatives Capable of Wild Type Androgen Receptor Activation
- (2014) Elahe A Mostaghel International Journal of Biological Sciences
- Modulation of Androgen Receptor by FOXA1 and FOXO1 Factors in Prostate Cancer
- (2014) Yu Zhao et al. International Journal of Biological Sciences
- Targeting Androgen Receptor Action for Prostate Cancer Treatment: Does the Post-Receptor Level Provide Novel Opportunities?
- (2014) Hannelore V. Heemers International Journal of Biological Sciences
- Roles for the Backdoor Pathway of Androgen Metabolism in Prostate Cancer Response to Castration and Drug Treatment
- (2014) Michael V. Fiandalo et al. International Journal of Biological Sciences
- Selectively Targeting the DNA-binding Domain of the Androgen Receptor as a Prospective Therapy for Prostate Cancer
- (2014) Kush Dalal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Intense Androgen-Deprivation Therapy With Abiraterone Acetate Plus Leuprolide Acetate in Patients With Localized High-Risk Prostate Cancer: Results of a Randomized Phase II Neoadjuvant Study
- (2014) Mary-Ellen Taplin et al. JOURNAL OF CLINICAL ONCOLOGY
- Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer
- (2014) Irfan A. Asangani et al. NATURE
- AR-V7 and Resistance to Enzalutamide and Abiraterone in Prostate Cancer
- (2014) Emmanuel S. Antonarakis et al. NEW ENGLAND JOURNAL OF MEDICINE
- Steroid Receptors Aplenty in Prostate Cancer
- (2014) Nima Sharifi NEW ENGLAND JOURNAL OF MEDICINE
- Enzalutamide in Metastatic Prostate Cancer before Chemotherapy
- (2014) Tomasz M. Beer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Targeting the androgen receptor pathway in castration-resistant prostate cancer: progresses and prospects
- (2014) R Ferraldeschi et al. ONCOGENE
- Destruction of Full-Length Androgen Receptor by Wild-Type SPOP, but Not Prostate-Cancer-Associated Mutants
- (2014) Jian An et al. Cell Reports
- Glucocorticoid Receptor Confers Resistance to Antiandrogens by Bypassing Androgen Receptor Blockade
- (2013) Vivek K. Arora et al. CELL
- A Gain-of-Function Mutation in DHT Synthesis in Castration-Resistant Prostate Cancer
- (2013) Kai-Hsiung Chang et al. CELL
- Mechanisms of Androgen Receptor Activation in Castration-Resistant Prostate Cancer
- (2013) Nima Sharifi ENDOCRINOLOGY
- Targeted Androgen Pathway Suppression in Localized Prostate Cancer: A Pilot Study
- (2013) Elahe A. Mostaghel et al. JOURNAL OF CLINICAL ONCOLOGY
- TMPRSS2:ERG Gene Fusion Predicts Subsequent Detection of Prostate Cancer in Patients With High-Grade Prostatic Intraepithelial Neoplasia
- (2013) Kyung Park et al. JOURNAL OF CLINICAL ONCOLOGY
- AKR1C3 as a target in castrate resistant prostate cancer
- (2013) Adegoke O. Adeniji et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Docetaxel and dasatinib or placebo in men with metastatic castration-resistant prostate cancer (READY): a randomised, double-blind phase 3 trial
- (2013) John C Araujo et al. LANCET ONCOLOGY
- Androgen Induces a Switch from Cytoplasmic Retention to Nuclear Import of the Androgen Receptor
- (2013) L. Ni et al. MOLECULAR AND CELLULAR BIOLOGY
- Mechanisms of the androgen receptor splicing in prostate cancer cells
- (2013) L L Liu et al. ONCOGENE
- Serum testosterone levels after medical or surgical androgen deprivation: A comprehensive review of the literature
- (2013) Tsutomu Nishiyama UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
- Peptidomimetic targeting of critical androgen receptor–coregulator interactions in prostate cancer
- (2013) Preethi Ravindranathan et al. Nature Communications
- Overcoming mutation-based resistance to antiandrogens with rational drug design
- (2013) Minna D Balbas et al. eLife
- The Androgen Receptor Induces a Distinct Transcriptional Program in Castration-Resistant Prostate Cancer in Man
- (2012) Naomi L. Sharma et al. CANCER CELL
- Abstract 4611: Cancer reversal by dual strategy: A new molecular target?
- (2012) Mario G. Gosalvez CANCER RESEARCH
- FoxA1 Specifies Unique Androgen and Glucocorticoid Receptor Binding Events in Prostate Cancer Cells
- (2012) B. Sahu et al. CANCER RESEARCH
- Androgen Receptor Splice Variants Mediate Enzalutamide Resistance in Castration-Resistant Prostate Cancer Cell Lines
- (2012) Y. Li et al. CANCER RESEARCH
- Dutasteride Treatment Over 2 Years Delays Prostate-specific Antigen Progression in Patients with Biochemical Failure After Radical Therapy for Prostate Cancer: Results from the Randomised, Placebo-controlled Avodart After Radical Therapy for Prostate Cancer Study (ARTS)
- (2012) Fritz Schröder et al. EUROPEAN UROLOGY
- Dutasteride in localised prostate cancer management: the REDEEM randomised, double-blind, placebo-controlled trial
- (2012) Neil E Fleshner et al. LANCET
- The mutational landscape of lethal castration-resistant prostate cancer
- (2012) Catherine S. Grasso et al. NATURE
- Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer
- (2012) Christopher E Barbieri et al. NATURE GENETICS
- Prostate cancer—from steroid transformations to clinical translation
- (2012) Kai-Hsiung Chang et al. Nature Reviews Urology
- Germline Mutations inHOXB13and Prostate-Cancer Risk
- (2012) Charles M. Ewing et al. NEW ENGLAND JOURNAL OF MEDICINE
- Increased Survival with Enzalutamide in Prostate Cancer after Chemotherapy
- (2012) Howard I. Scher et al. NEW ENGLAND JOURNAL OF MEDICINE
- AR intragenic deletions linked to androgen receptor splice variant expression and activity in models of prostate cancer progression
- (2012) Y Li et al. ONCOGENE
- Steroid biosynthesis and prostate cancer
- (2012) Nima Sharifi et al. STEROIDS
- Role of 5α-Reductase Inhibitors in Prostate Cancer Prevention and Treatment
- (2012) Faris Azzouni et al. UROLOGY
- Intragenic Rearrangement and Altered RNA Splicing of the Androgen Receptor in a Cell-Based Model of Prostate Cancer Progression
- (2011) Y. Li et al. CANCER RESEARCH
- Resistance to CYP17A1 Inhibition with Abiraterone in Castration-Resistant Prostate Cancer: Induction of Steroidogenesis and Androgen Receptor Splice Variants
- (2011) Elahe A. Mostaghel et al. CLINICAL CANCER RESEARCH
- Androgen Receptor Cofactors in Prostate Cancer: Potential Therapeutic Targets of Castration-Resistant Prostate Cancer
- (2011) Masaki Shiota et al. CURRENT CANCER DRUG TARGETS
- Selective Roles for cAMP Response Element-binding Protein Binding Protein and p300 Protein as Coregulators for Androgen-regulated Gene Expression in Advanced Prostate Cancer Cells
- (2011) Irina Ianculescu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Clinical and Biochemical Consequences of CYP17A1 Inhibition with Abiraterone Given with and without Exogenous Glucocorticoids in Castrate Men with Advanced Prostate Cancer
- (2011) Gerhardt Attard et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Androgen Receptor Rediscovered: The New Biology and Targeting the Androgen Receptor Therapeutically
- (2011) Charles J. Ryan et al. JOURNAL OF CLINICAL ONCOLOGY
- Small Molecule Inhibition of the Steroid Receptor Coactivators, SRC-3 and SRC-1
- (2011) Ying Wang et al. MOLECULAR ENDOCRINOLOGY
- Minireview: Alternative Activation Pathways for the Androgen Receptor in Prostate Cancer
- (2011) Kristin R. Lamont et al. MOLECULAR ENDOCRINOLOGY
- Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA
- (2011) Dong Wang et al. NATURE
- The genomic complexity of primary human prostate cancer
- (2011) Michael F. Berger et al. NATURE
- Abiraterone and Increased Survival in Metastatic Prostate Cancer
- (2011) Johann S. de Bono et al. NEW ENGLAND JOURNAL OF MEDICINE
- Dihydrotestosterone synthesis bypasses testosterone to drive castration-resistant prostate cancer
- (2011) K.-H. Chang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Serum/glucocorticoid-regulated kinase 1 expression in primary human prostate cancers
- (2011) Russell Z. Szmulewitz et al. PROSTATE
- Evidence of Limited Contributions for Intratumoral Steroidogenesis in Prostate Cancer
- (2010) J. Hofland et al. CANCER RESEARCH
- 3β-Hydroxysteroid Dehydrogenase Is a Possible Pharmacological Target in the Treatment of Castration-Resistant Prostate Cancer
- (2010) Kristen Evaul et al. ENDOCRINOLOGY
- New agents and strategies for the hormonal treatment of castration-resistant prostate cancer
- (2010) Nima Sharifi EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Dihydrotestosterone Administration Does Not Increase Intraprostatic Androgen Concentrations or Alter Prostate Androgen Action in Healthy Men: A Randomized-Controlled Trial
- (2010) Stephanie T. Page et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant
- (2010) Shihua Sun et al. JOURNAL OF CLINICAL INVESTIGATION
- Steroid 5 α-reductase inhibitors targeting BPH and prostate cancer
- (2010) Lucy J. Schmidt et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Inhibitors of type 5 17β-hydroxysteroid dehydrogenase (AKR1C3): Overview and structural insights
- (2010) Michael C. Byrns et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor
- (2010) P. A. Watson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- 5α-Reductase Isozymes and Androgen Actions in the Prostate
- (2009) Yuan-Shan Zhu et al. Annals of the New York Academy of Sciences
- Unraveling the Complexities of Androgen Receptor Signaling in Prostate Cancer Cells
- (2009) Hannelore V. Heemers et al. CANCER CELL
- Characterization of ERG, AR and PTEN Gene Status in Circulating Tumor Cells from Patients with Castration-Resistant Prostate Cancer
- (2009) G. Attard et al. CANCER RESEARCH
- A Novel Androgen Receptor Splice Variant Is Up-regulated during Prostate Cancer Progression and Promotes Androgen Depletion-Resistant Growth
- (2009) Z. Guo et al. CANCER RESEARCH
- Androgen Receptor Regulates a Distinct Transcription Program in Androgen-Independent Prostate Cancer
- (2009) Qianben Wang et al. CELL
- Nuclear Receptor-Induced Chromosomal Proximity and DNA Breaks Underlie Specific Translocations in Cancer
- (2009) Chunru Lin et al. CELL
- Starving the Addiction: New Opportunities for Durable Suppression of AR Signaling in Prostate Cancer
- (2009) K. E. Knudsen et al. CLINICAL CANCER RESEARCH
- ETS Gene Fusions in Prostate Cancer: From Discovery to Daily Clinical Practice
- (2009) Scott A. Tomlins et al. EUROPEAN UROLOGY
- Molecular mechanisms of castration-resistant prostate cancer progression
- (2009) Smitha S Dutt et al. Future Oncology
- Type 5 17β-Hydroxysteroid Dehydrogenase (AKR1C3) Contributes to Testosterone Production in the Adrenal Reticularis
- (2009) Yasuhiro Nakamura et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Androgen Modulation of Coregulator Expression in Prostate Cancer Cells
- (2009) Hannelore V. Heemers et al. MOLECULAR ENDOCRINOLOGY
- Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis
- (2009) Jennifer C King et al. NATURE GENETICS
- Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate
- (2009) Brett S Carver et al. NATURE GENETICS
- A FOXA1-binding enhancer regulates Hoxb13 expression in the prostate gland
- (2009) R. P. McMullin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Induced Chromosomal Proximity and Gene Fusions in Prostate Cancer
- (2009) R.-S. Mani et al. SCIENCE
- Development of a Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer
- (2009) C. Tran et al. SCIENCE
- Coactivator selective regulation of androgen receptor activity
- (2009) Irina U. Agoulnik et al. STEROIDS
- The human glucocorticoid receptor: Molecular basis of biologic function
- (2009) Nicolas C. Nicolaides et al. STEROIDS
- Splicing of a Novel Androgen Receptor Exon Generates a Constitutively Active Androgen Receptor that Mediates Prostate Cancer Therapy Resistance
- (2008) S. M. Dehm et al. CANCER RESEARCH
- Maintenance of Intratumoral Androgens in Metastatic Prostate Cancer: A Mechanism for Castration-Resistant Tumor Growth
- (2008) R. B. Montgomery et al. CANCER RESEARCH
- Ligand-Independent Androgen Receptor Variants Derived from Splicing of Cryptic Exons Signify Hormone-Refractory Prostate Cancer
- (2008) R. Hu et al. CANCER RESEARCH
- Characterization of Nuclear Import of the Domain-Specific Androgen Receptor in Association with the Importin α/β and Ran-Guanosine 5′-Triphosphate Systems
- (2008) Natsuko Kaku et al. ENDOCRINOLOGY
- Site-specific Androgen Receptor Serine Phosphorylation Linked to Epidermal Growth Factor-dependent Growth of Castration-recurrent Prostate Cancer
- (2008) Liliana A. Ponguta et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phase II Study of Dutasteride for Recurrent Prostate Cancer During Androgen Deprivation Therapy
- (2008) Satyan K. Shah et al. JOURNAL OF UROLOGY
- Minireview: The Intersection of Steroid Receptors with Molecular Chaperones: Observations and Questions
- (2008) David F. Smith et al. MOLECULAR ENDOCRINOLOGY
- Effect of Dutasteride on Intraprostatic Androgen Levels in Men With Benign Prostatic Hyperplasia or Prostate Cancer
- (2008) Roger Rittmaster et al. UROLOGY
- Type 1 and Type 2 5α-Reductase Expression in the Development and Progression of Prostate Cancer
- (2007) Lynn N. Thomas et al. EUROPEAN UROLOGY
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