Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer
出版年份 2014 全文链接
标题
Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer
作者
关键词
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出版物
NATURE
Volume 510, Issue 7504, Pages 278-282
出版商
Springer Nature
发表日期
2014-04-23
DOI
10.1038/nature13229
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers
- (2013) Jakob Lovén et al. CELL
- Phospho Switch Triggers Brd4 Chromatin Binding and Activator Recruitment for Gene-Specific Targeting
- (2013) Shwu-Yuan Wu et al. MOLECULAR CELL
- ETS factors reprogram the androgen receptor cistrome and prime prostate tumorigenesis in response to PTEN loss
- (2013) Yu Chen et al. NATURE MEDICINE
- Androgen Receptor Promotes Ligand-Independent Prostate Cancer Progression through c-Myc Upregulation
- (2013) Lina Gao et al. PLoS One
- Anti-androgen receptor ASC-J9 versus anti-androgens MDV3100 (Enzalutamide) or Casodex (Bicalutamide) leads to opposite effects on prostate cancer metastasis via differential modulation of macrophage infiltration and STAT3-CCL2 signaling
- (2013) T-H Lin et al. Cell Death & Disease
- Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition
- (2013) Alexandre Puissant et al. Cancer Discovery
- Software for Computing and Annotating Genomic Ranges
- (2013) Michael Lawrence et al. PLoS Computational Biology
- Overcoming mutation-based resistance to antiandrogens with rational drug design
- (2013) Minna D Balbas et al. eLife
- Small-Molecule Inhibition of BRDT for Male Contraception
- (2012) Martin M. Matzuk et al. CELL
- Abiraterone in Prostate Cancer: A New Angle to an Old Problem
- (2012) M. N. Stein et al. CLINICAL CANCER RESEARCH
- MDV3100 for the treatment of prostate cancer
- (2012) Deborah Mukherji et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Characterization of the EZH2-MMSET Histone Methyltransferase Regulatory Axis in Cancer
- (2012) Irfan A. Asangani et al. MOLECULAR CELL
- The mutational landscape of lethal castration-resistant prostate cancer
- (2012) Catherine S. Grasso et al. NATURE
- Fast gapped-read alignment with Bowtie 2
- (2012) Ben Langmead et al. NATURE METHODS
- Increased Survival with Enzalutamide in Prostate Cancer after Chemotherapy
- (2012) Howard I. Scher et al. NEW ENGLAND JOURNAL OF MEDICINE
- Sensitivity of human lung adenocarcinoma cell lines to targeted inhibition of BET epigenetic signaling proteins
- (2012) W. W. Lockwood et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- BRD4 is an atypical kinase that phosphorylates Serine2 of the RNA Polymerase II carboxy-terminal domain
- (2012) B. N. Devaiah et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- False positive peaks in ChIP-seq and other sequencing-based functional assays caused by unannotated high copy number regions
- (2011) Joseph K. Pickrell et al. BIOINFORMATICS
- BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc
- (2011) Jake E. Delmore et al. CELL
- New Strategies in Metastatic Prostate Cancer: Targeting the Androgen Receptor Signaling Pathway
- (2011) G. Attard et al. CLINICAL CANCER RESEARCH
- Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
- (2011) Mark A. Dawson et al. NATURE
- Abiraterone and Increased Survival in Metastatic Prostate Cancer
- (2011) Johann S. de Bono et al. NEW ENGLAND JOURNAL OF MEDICINE
- Targeting MYC dependence in cancer by inhibiting BET bromodomains
- (2011) J. A. Mertz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- BEDTools: a flexible suite of utilities for comparing genomic features
- (2010) Aaron R. Quinlan et al. BIOINFORMATICS
- HPeak: an HMM-based algorithm for defining read-enriched regions in ChIP-Seq data
- (2010) Zhaohui S Qin et al. BMC BIOINFORMATICS
- Integrative Genomic Profiling of Human Prostate Cancer
- (2010) Barry S. Taylor et al. CANCER CELL
- Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant
- (2010) Shihua Sun et al. JOURNAL OF CLINICAL INVESTIGATION
- Significant and Sustained Antitumor Activity in Post-Docetaxel, Castration-Resistant Prostate Cancer With the CYP17 Inhibitor Abiraterone Acetate
- (2010) Alison H.M. Reid et al. JOURNAL OF CLINICAL ONCOLOGY
- Selective inhibition of BET bromodomains
- (2010) Panagis Filippakopoulos et al. NATURE
- The Sequence Alignment/Map format and SAMtools
- (2009) H. Li et al. BIOINFORMATICS
- Development of a Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer
- (2009) C. Tran et al. SCIENCE
- Androgen deprivation therapy: progress in understanding mechanisms of resistance and optimizing androgen depletion
- (2009) William P Harris et al. Nature clinical practice. Urology
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