Citrate Suppresses Tumor Growth in Multiple Models through Inhibition of Glycolysis, the Tricarboxylic Acid Cycle and the IGF-1R Pathway
出版年份 2017 全文链接
标题
Citrate Suppresses Tumor Growth in Multiple Models through Inhibition of Glycolysis, the Tricarboxylic Acid Cycle and the IGF-1R Pathway
作者
关键词
-
出版物
Scientific Reports
Volume 7, Issue 1, Pages -
出版商
Springer Nature
发表日期
2017-06-27
DOI
10.1038/s41598-017-04626-4
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Inhibition of MUC1-C Suppresses MYC Expression and Attenuates Malignant Growth in KRAS Mutant Lung Adenocarcinomas
- (2016) Audrey Bouillez et al. CANCER RESEARCH
- The reduced concentration of citrate in cancer cells: An indicator of cancer aggressiveness and a possible therapeutic target
- (2016) Icard Philippe et al. DRUG RESISTANCE UPDATES
- Mucin 1-mediated chemo-resistance in lung cancer cells
- (2016) S Y Ham et al. Oncogenesis
- Clinical significance of IGF1R gene expression in patients with Stage II/III gastric cancer who receive curative surgery and adjuvant chemotherapy with S-1
- (2015) Koji Numata et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Targeting Lactate Dehydrogenase-A Inhibits Tumorigenesis and Tumor Progression in Mouse Models of Lung Cancer and Impacts Tumor-Initiating Cells
- (2014) Han Xie et al. Cell Metabolism
- Citrate Synthase Expression Affects Tumor Phenotype and Drug Resistance in Human Ovarian Carcinoma
- (2014) Lilan Chen et al. PLoS One
- Expression of insulin-like growth factor receptor type 1 correlate with lymphatic metastases in human gastric cancer
- (2014) Mariusz Gryko et al. POLISH JOURNAL OF PATHOLOGY
- MUC1: a multifaceted oncoprotein with a key role in cancer progression
- (2014) Sritama Nath et al. TRENDS IN MOLECULAR MEDICINE
- Knockdown of Malic Enzyme 2 Suppresses Lung Tumor Growth, Induces Differentiation and Impacts PI3K/AKT Signaling
- (2014) Jian-Guo Ren et al. Scientific Reports
- A critical role for citrate metabolism in LPS signalling
- (2013) Luke A. J. O'Neill BIOCHEMICAL JOURNAL
- Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function
- (2013) Madhusudhanan Sukumar et al. JOURNAL OF CLINICAL INVESTIGATION
- Spermine and Citrate as Metabolic Biomarkers for Assessing Prostate Cancer Aggressiveness
- (2013) Guro F. Giskeødegård et al. PLoS One
- PTEN-regulated AKT/FoxO3a/Bim signaling contributes to reactive oxygen species-mediated apoptosis in selenite-treated colorectal cancer cells
- (2013) H Luo et al. Cell Death & Disease
- ATP citrate lyase knockdown impacts cancer stem cells in vitro
- (2013) J-i Hanai et al. Cell Death & Disease
- Inhibition of Mcl-1 expression by citrate enhances the effect of Bcl-xL inhibitors on human ovarian carcinoma cells
- (2013) Hubert Lincet et al. Journal of Ovarian Research
- Citrate kills tumor cells through activation of apical caspases
- (2012) Björn Kruspig et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Small Interfering RNA Targeted to IGF-IR Delays Tumor Growth and Induces Proinflammatory Cytokines in a Mouse Breast Cancer Model
- (2012) Tiphanie Durfort et al. PLoS One
- A model for cancer-suppressive inflammation
- (2012) Ole Audun Werner Haabeth et al. OncoImmunology
- The mitochondrial citrate carrier: a new player in inflammation
- (2011) Vittoria Infantino et al. BIOCHEMICAL JOURNAL
- Inhibition of lung cancer growth: ATP citrate lyase knockdown and statin treatment leads to dual blockade of mitogen-activated protein Kinase (MAPK) and Phosphatidylinositol-3-kinase (PI3K)/AKT pathways
- (2011) Jun-ichi Hanai et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Clinical report: A patient with primary peritoneal mesothelioma that has improved after taking citric acid orally
- (2011) A.H. Bucay Clinics and Research in Hepatology and Gastroenterology
- High IGF-IR Activity in Triple-Negative Breast Cancer Cell Lines and Tumorgrafts Correlates with Sensitivity to Anti-IGF-IR Therapy
- (2010) B. C. Litzenburger et al. CLINICAL CANCER RESEARCH
- Insulin-Like Growth Factor-I Regulation of Immune Function: A Potential Therapeutic Target in Autoimmune Diseases?
- (2010) T. J. Smith PHARMACOLOGICAL REVIEWS
- Induction of Erythroid Differentiation in Human Erythroleukemia Cells by Depletion of Malic Enzyme 2
- (2010) Jian-Guo Ren et al. PLoS One
- Phase II Study of the Anti–Insulin-Like Growth Factor Type 1 Receptor Antibody CP-751,871 in Combination With Paclitaxel and Carboplatin in Previously Untreated, Locally Advanced, or Metastatic Non–Small-Cell Lung Cancer
- (2009) Daniel D. Karp et al. JOURNAL OF CLINICAL ONCOLOGY
- Hypothesis proved…citric acid (citrate) does improve cancer: A case of a patient suffering from medullary thyroid cancer
- (2009) Alberto Halabe Bucay MEDICAL HYPOTHESES
- High Expression Levels of Total IGF-1R and Sensitivity of NSCLC Cells In Vitro to an Anti-IGF-1R Antibody (R1507)
- (2009) Yixuan Gong et al. PLoS One
- Tumor Suppression by PTEN Requires the Activation of the PKR-eIF2 Phosphorylation Pathway
- (2009) Z. Mounir et al. Science Signaling
- Insulin, insulin-like growth factors and neoplasia
- (2008) Michael Pollak BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
- Targeting insulin and insulin-like growth factor signalling in oncology
- (2008) Michael Pollak CURRENT OPINION IN PHARMACOLOGY
- Is Akt the “Warburg kinase”?—Akt-energy metabolism interactions and oncogenesis
- (2008) R. Brooks Robey et al. SEMINARS IN CANCER BIOLOGY
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