Total synthesis of aristolactam alkaloids via synergistic C–H bond activation and dehydro-Diels–Alder reactions

Employing Arynes in Diels–Alder Reactions and Transition-Metal-Free Multicomponent Coupling and Arylation Reactions

(2016) Sachin Suresh Bhojgude et al.   ACCOUNTS OF CHEMICAL RESEARCH

A Simple and Versatile Amide Directing Group for C−H Functionalizations

(2016) Ru-Yi Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Kinetic Resolution of β-Sulfonyl Ketones through Enantioselective β-Elimination using a Cation-Binding Polyether Catalyst

(2015) Liang Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ruthenium Oxidase Catalysis for Site-Selective C-H Alkenylations with Ambient O2 as the Sole Oxidant

(2015) Alexander Bechtoldt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of isoindolinones via a ruthenium-catalyzed cyclization of N-substituted benzamides with allylic alcohols

(2015) Ramasamy Manoharan et al.   CHEMICAL COMMUNICATIONS

Transition-Metal-Catalyzed π-Bond-Assisted CH Bond Functionalization: An Emerging Trend in Organic Synthesis

(2015) Parthasarathy Gandeepan et al.   Chemistry-An Asian Journal

Total Syntheses of Aporphine Alkaloids via Benzyne Chemistry: An Approach to the Formation of Aporphine Cores

(2015) Allan F. C. Rossini et al.   JOURNAL OF ORGANIC CHEMISTRY

The Aryne aza-Diels–Alder Reaction: Flexible Syntheses of Isoquinolines

(2015) Juan-Carlos Castillo et al.   ORGANIC LETTERS

A convenient formation of aporphine core via benzyne chemistry: conformational analysis and synthesis of ( R )-aporphine

(2015) Givago P. Perecim et al.   TETRAHEDRON LETTERS

Triple aryne–tetrazine reaction enabling rapid access to a new class of polyaromatic heterocycles

(2015) Sung-Eun Suh et al.   Chemical Science

Ruthenium-Catalyzed ortho Alkenylation of Aromatics with Alkenes at Room Temperature with Hydrogen Evolution

(2015) Rajendran Manikandan et al.   ACS Catalysis

Rhodium(III)-Catalyzed Oxidative Olefination of Picolinamides: Convenient Synthesis of 3-Alkenylpicolinamides

(2014) Jun Zhou et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis of alkylidene pyrrolo[3,4-b]pyridin-7-one derivatives via RhIII-catalyzed cascade oxidative alkenylation/annulation of picolinamides

(2014) Ángel Manu Martínez et al.   CHEMICAL COMMUNICATIONS

Amidines for Versatile Ruthenium(II)-Catalyzed Oxidative CH Activations with Internal Alkynes and Acrylates

(2014) Jie Li et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Tandem Reaction of Benzyne with Functionalized Benzylidenephthalan To Afford Phenanthro[10,1-bc]furan

(2014) Hai Xiao Siyang et al.   JOURNAL OF ORGANIC CHEMISTRY

The Role of Aryne Distortions, Steric Effects, and Charges in Regioselectivities of Aryne Reactions

(2014) Jose M. Medina et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Naturally occurring aristolochic acid analogues and their toxicities

(2014) Johanna Michl et al.   NATURAL PRODUCT REPORTS

Rh(III)-Catalyzed Cascade Oxidative Olefination/Cyclization of Picolinamides and Alkenes via C–H Activation

(2014) Shangjun Cai et al.   ORGANIC LETTERS

Ruthenium-Catalyzed Cyclization of Aromatic Nitriles with Alkenes: Stereoselective Synthesis of (Z)-3-Methyleneisoindolin-1-ones

(2014) Mallu Chenna Reddy et al.   ORGANIC LETTERS

Efficient Synthesis of 9-Aryldihydrophenanthrenes by a Cascade Reaction Involving Arynes and Styrenes

(2014) Sachin Suresh Bhojgude et al.   ORGANIC LETTERS

Carboxylate-Assisted Ruthenium-Catalyzed Alkyne Annulations by C–H/Het–H Bond Functionalizations

(2013) Lutz Ackermann   ACCOUNTS OF CHEMICAL RESEARCH

Rhodium(III)-Catalyzed Amidation of Aryl KetoneO-Methyl Oximes with Isocyanates by CH Activation: Convergent Synthesis of 3-Methyleneisoindolin-1-ones

(2013) Bing Zhou et al.   CHEMISTRY-A EUROPEAN JOURNAL

Iodine/Water-Mediated Oxidation ofo-Alkynylaroyl Compounds and Application of the Products of Oxidation in the Synthesis of Nitrogen Heterocycles

(2013) Karuppusamy Sakthivel et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Arynes and Cyclohexyne in Natural Product Synthesis

(2012) Christian M. Gampe et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Efficient and Practical Total Synthesis of Sauristolactam

(2012) Jung-Nyoung Heo et al.   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

A general approach to the synthesis of enantiopure 19-nor-Vitamin D3 and its C-2 phosphate analogs prepared from cyclohexadienyl sulfone

(2012) Vikas Sikervar et al.   CHEMICAL COMMUNICATIONS

Ruthenium(II)-Catalyzed C–H Bond Activation and Functionalization

(2012) Percia Beatrice Arockiam et al.   CHEMICAL REVIEWS

A Comprehensive History of Arynes in Natural Product Total Synthesis

(2012) Pamela M. Tadross et al.   CHEMICAL REVIEWS

Recent advances in transition-metal-free carbon–carbon and carbon–heteroatom bond-forming reactions using arynes

(2012) Anup Bhunia et al.   CHEMICAL SOCIETY REVIEWS

Amide-Directed Tandem CC/CN Bond Formation through CH Activation

(2012) Chen Zhu et al.   Chemistry-An Asian Journal

The hexadehydro-Diels–Alder reaction

(2012) Thomas R. Hoye et al.   NATURE

Regioselective reactions of 3,4-pyridynes enabled by the aryne distortion model

(2012) Adam E. Goetz et al.   Nature Chemistry

Rhodium(iii)-catalyzed oxidative mono- and di-olefination of isonicotinamides

(2012) Xiaohong Wei et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Construction of Naphtho-Fused Oxindoles via the Aryne Diels–Alder Reaction with Methyleneindolinones

(2012) Jian Li et al.   ORGANIC LETTERS

Ru(II)-Catalyzed Amidation of 2-Arylpyridines with Isocyanates via C–H Activation

(2012) Krishnamoorthy Muralirajan et al.   ORGANIC LETTERS

Pyridocoumarin, aristolactam and aporphine alkaloids from the Australian rainforest plant Goniothalamus australis

(2012) Claire Levrier et al.   PHYTOCHEMISTRY

Weak Coordination as a Powerful Means for Developing Broadly Useful C–H Functionalization Reactions

(2011) Keary M. Engle et al.   ACCOUNTS OF CHEMICAL RESEARCH

Synthesis of isoindolinones via palladium-catalyzed C–H activation of N-methoxybenzamides

(2011) Dan-Dan Li et al.   CHEMICAL COMMUNICATIONS

Intermolecular Dehydrogenative Heck Reactions

(2011) Jean Le Bras et al.   CHEMICAL REVIEWS

Autocatalysis for C–H Bond Activation by Ruthenium(II) Complexes in Catalytic Arylation of Functional Arenes

(2011) Emmanuel Ferrer Flegeau et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ruthenium-CatalyzedOrtho-Alkenylation of Aromatic Ketones with Alkenes by C–H Bond Activation

(2011) Kishor Padala et al.   ORGANIC LETTERS

Ruthenium-Catalyzed Oxidative Vinylation of Heteroarene Carboxylic Acids with Alkenes via Regioselective C−H Bond Cleavage

(2011) Takumi Ueyama et al.   ORGANIC LETTERS

New Heteroannulation Reactions ofN-Alkoxybenzamides by Pd(II) Catalyzed C–H Activation

(2011) Joe W. Wrigglesworth et al.   ORGANIC LETTERS

Rhodium-Catalyzed Oxidative Olefination of CH Bonds in Acetophenones and Benzamides

(2010) Frederic W. Patureau et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions

(2010) Thomas W. Lyons et al.   CHEMICAL REVIEWS

Oxidative Coupling of Aromatic Substrates with Alkynes and Alkenes under Rhodium Catalysis

(2010) Tetsuya Satoh et al.   CHEMISTRY-A EUROPEAN JOURNAL

Pd(II)-Catalyzed Hydroxyl-Directed C−H Olefination Enabled by Monoprotected Amino Acid Ligands

(2010) Yi Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of aristolactam analogues and evaluation of their antitumor activity

(2009) Young Lok Choi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Rhodium-Catalyzed C−C Bond Formation via Heteroatom-Directed C−H Bond Activation

(2009) Denise A. Colby et al.   CHEMICAL REVIEWS

A Concise Total Synthesis of (−)-Quinocarcin via Aryne Annulation

(2008) Kevin M. Allan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis of Aristolactams via a One-Pot Suzuki−Miyaura Coupling/Aldol Condensation Cascade Reaction

(2008) Joa Kyum Kim et al.   ORGANIC LETTERS