Transition-Metal-Catalyzed π-Bond-Assisted CH Bond Functionalization: An Emerging Trend in Organic Synthesis

Low-Valent Cobalt Catalysis: New Opportunities for C–H Functionalization

(2014) Ke Gao et al.   ACCOUNTS OF CHEMICAL RESEARCH

Regioselective Synthesis of IndolesviaRhodium-Catalyzed CH Activation Directed by anIn-SituGenerated Redox-Neutral Group

(2014) Krishnamoorthy Muralirajan et al.   ADVANCED SYNTHESIS & CATALYSIS

Carboxylate-Directed CH Functionalization

(2014) Guangfa Shi et al.   ADVANCED SYNTHESIS & CATALYSIS

Weakly Coordinating Directing Groups for Ruthenium(II)- Catalyzed CH Activation

(2014) Suman De Sarkar et al.   ADVANCED SYNTHESIS & CATALYSIS

Ruthenium(II)-Catalyzed CH Bond Activation: An Efficient Route toward Indenamines

(2014) Chen-Hsun Hung et al.   ChemCatChem

Ruthenium-catalyzed ortho-arylation of acetanilides with aromatic boronic acids: an easy route to prepare phenanthridines and carbazoles

(2014) Ravi Kiran Chinnagolla et al.   CHEMICAL COMMUNICATIONS

Rh(iii)-catalyzed synthesis of 1-substituted isoquinolinium salts via a C–H bond activation reaction of ketimines with alkynes

(2014) Natarajan Senthilkumar et al.   CHEMICAL COMMUNICATIONS

Palladium-catalyzed Annulation of 2-Substituted Silylethynyloxybiaryls through δ-C–H Activation

(2014) Yasunori Minami et al.   CHEMISTRY LETTERS

Palladium-catalyzed Cycloaddition of Aryl Silylethynyl Ethers with Isocyanates via o-C–H Cleavage

(2014) Yasunori Minami et al.   CHEMISTRY LETTERS

ortho-Benzoxylation ofN-Alkyl Benzamides with Aromatic Acids Catalyzed by Ruthenium(II) Complex

(2014) Kishor Padala et al.   CHEMISTRY-A EUROPEAN JOURNAL

Ruthenium(II)-Catalyzed Synthesis of Isochromenes by CH Activation with Weakly Coordinating Aliphatic Hydroxyl Groups

(2014) Sachiyo Nakanowatari et al.   CHEMISTRY-A EUROPEAN JOURNAL

Palladium-Catalyzed Alkenylation via sp2 C–H Bond Activation Using Phenolic Hydroxyl as the Directing Group

(2014) Chun Zhang et al.   JOURNAL OF ORGANIC CHEMISTRY

Pd-Catalyzed Synthesis of 9,9′-Bifluorenylidene Derivatives via Dual C–H Activation of Bis-biaryl Alkynes

(2014) Jian Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent advances in homogeneous nickel catalysis

(2014) Sarah Z. Tasker et al.   NATURE

RhIII-catalyzed dual directing group assisted sterically hindered C–H bond activation: a unique route to meta and ortho substituted benzofurans

(2014) Chien-Hung Yeh et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of Carbazoles by Copper-Catalyzed Intramolecular C–H/N–H Coupling

(2014) Kazutaka Takamatsu et al.   ORGANIC LETTERS

Transition-metal-catalyzed ketone-directed ortho-C–H functionalization reactions

(2014) Qing-Zhong Zheng et al.   TETRAHEDRON LETTERS

Carboxylate-Assisted Ruthenium-Catalyzed Alkyne Annulations by C–H/Het–H Bond Functionalizations

(2013) Lutz Ackermann   ACCOUNTS OF CHEMICAL RESEARCH

Palladium-Catalyzed Hydrobenzylation ofortho-Tolyl Alkynyl Ethers by Benzylic CH Activation: Remarkable Alkynoxy-Directing Effect

(2013) Yasunori Minami et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct Access to Benzo[b]furans through Palladium-Catalyzed Oxidative Annulation of Phenols and Unactivated Internal Alkynes

(2013) Malleswara Rao Kuram et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A regioselective synthesis of 1-haloisoquinolines via ruthenium-catalyzed cyclization of O-methylbenzohydroximoyl halides with alkynes

(2013) Ravi Kiran Chinnagolla et al.   CHEMICAL COMMUNICATIONS

A convenient synthesis of quinolizinium salts through Rh(iii) or Ru(ii)-catalyzed C–H bond activation of 2-alkenylpyridines

(2013) Ching-Zong Luo et al.   CHEMICAL COMMUNICATIONS

C–H nitrogenation and oxygenation by ruthenium catalysis

(2013) Vedhagiri S. Thirunavukkarasu et al.   CHEMICAL COMMUNICATIONS

Oxidative C–H amination reactions

(2013) Marie-Laure Louillat et al.   CHEMICAL SOCIETY REVIEWS

Palladium-catalyzed Cycloaddition of Alkynyl Aryl Ethers to Allenes to Form a 2,3-Bismethylidene-2,3-dihydro-4H-1-benzopyran Framework

(2013) Yasunori Minami et al.   CHEMISTRY LETTERS

RhIII-Catalyzed CH Activation: A Versatile Route towards Various Polycyclic Pyridinium Salts

(2013) Ching-Zong Luo et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rhodium-Catalyzed Annulative Coupling of 3-Phenylthiophenes with Alkynes Involving Double C-H Bond Cleavages

(2013) Tomonori Iitsuka et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rhodium(III)-Catalyzed Synthesis of Cinnolinium Salts from Azobenzenes and Alkynes: Application to the Synthesis of Indoles and Cinnolines

(2013) Krishnamoorthy Muralirajan et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of Phenanthridinones fromN-Methoxybenzamides and Aryltriethoxysilanes through RhIII-Catalyzed CH and NH Bond Activation

(2013) Natarajan Senthilkumar et al.   Chemistry-An Asian Journal

Aromatic C-H Addition to Ketones: The Effect of Directing Groups

(2013) Xi-Sha Zhang et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed Highly Selective ortho-Halogenation (I, Br, Cl) of Arylnitriles via sp2 C–H Bond Activation Using Cyano as Directing Group

(2013) Bingnan Du et al.   JOURNAL OF ORGANIC CHEMISTRY

C–H bond activation enables the rapid construction and late-stage diversification of functional molecules

(2013) Joanna Wencel-Delord et al.   Nature Chemistry

Palladium(II)-Catalyzed ortho-Olefination of Benzylic Phosphonic Monoesters

(2013) Xiangjian Meng et al.   ORGANIC LETTERS

Pd-Catalyzed π-Chelation Assisted ortho-C–H Activation and Annulation of Allylarenes with Internal Alkynes

(2013) Parthasarathy Gandeepan et al.   ORGANIC LETTERS

Rh(III)-Catalyzed Olefination of N-Sulfonyl Imines: Synthesis of Ortho-Olefinated Benzaldehydes

(2013) Tao Zhang et al.   ORGANIC LETTERS

Rh(III)-Catalyzed Coupling of Benzamides with Propargyl Alcohols via Hydroarylation–Lactonization

(2013) Fen Wang et al.   ORGANIC LETTERS

Novel Syntheses of Fluorenones via Nitrile-Directed Palladium-Catalyzed C–H and Dual C–H Bond Activation

(2013) Jung-Chih Wan et al.   ORGANIC LETTERS

Ruthenium-catalyzed oxidative alkyne annulation by C–H activation on ketimines

(2013) Jie Li et al.   TETRAHEDRON

C–H activation route to dibenzo[a,e]pentalenes: annulation of arylacetylenes promoted by PdCl2–AgOTf–o-chloranil

(2013) Takehisa Maekawa et al.   Chemical Science

Benzofuran synthesis via copper-mediated oxidative annulation of phenols and unactivated internal alkynes

(2013) Ruyi Zhu et al.   Chemical Science

Controlling Site Selectivity in Palladium-Catalyzed C–H Bond Functionalization

(2012) Sharon R. Neufeldt et al.   ACCOUNTS OF CHEMICAL RESEARCH

Synthesis of Olefin-Oxazoline Ligands (OlefOx) by Rhodium(III)-Catalyzed Oxidative Olefination

(2012) Nils Schröder et al.   ADVANCED SYNTHESIS & CATALYSIS

Ether-Directedortho-C-H Olefination with a Palladium(II)/Monoprotected Amino Acid Catalyst

(2012) Gang Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium(III)-Catalyzed CH Activation of Arenes Using a Versatile and Removable Triazene Directing Group

(2012) Chengming Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium(III)-Catalyzed Oxidative CH Coupling ofN-Methoxybenzamides with Aryl Boronic Acids: One-Pot Synthesis of Phenanthridinones

(2012) Jaganathan Karthikeyan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Beyond Directing Groups: Transition-Metal-Catalyzed CH Activation of Simple Arenes

(2012) Nadine Kuhl et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pd-catalyzed double C–H bond activation of diaryl ketones for the synthesis of fluorenones

(2012) Parthasarathy Gandeepan et al.   CHEMICAL COMMUNICATIONS

Ruthenium(II)-Catalyzed C–H Bond Activation and Functionalization

(2012) Percia Beatrice Arockiam et al.   CHEMICAL REVIEWS

C–C, C–O and C–N bond formation via rhodium(iii)-catalyzed oxidative C–H activation

(2012) Guoyong Song et al.   CHEMICAL SOCIETY REVIEWS

Amide-Directed Tandem CC/CN Bond Formation through CH Activation

(2012) Chen Zhu et al.   Chemistry-An Asian Journal

Cationic Ruthenium Catalysts for Alkyne Annulations with Oximes by C–H/N–O Functionalizations

(2012) Christoph Kornhaaß et al.   JOURNAL OF ORGANIC CHEMISTRY

Pd(OAc)2-Catalyzed Alkoxylation of Arylnitriles via sp2 C–H Bond Activation Using Cyano as the Directing Group

(2012) Wu Li et al.   JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed Cycloaddition of Alkynyl Aryl Ethers with Internal Alkynes via Selective Ortho C–H Activation

(2012) Yasunori Minami et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Allylic Carbon–Carbon Double Bond Directed Pd-Catalyzed Oxidative ortho-Olefination of Arenes

(2012) Parthasarathy Gandeepan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hydroxyl-Directed Ruthenium-Catalyzed C–H Bond Functionalization: Versatile Access to Fluorescent Pyrans

(2012) Vedhagiri S. Thirunavukkarasu et al.   ORGANIC LETTERS

Ru(II)-Catalyzed C–H Bond Activation for the Synthesis of Substituted Isoquinolinium Salts from Benzaldehydes, Amines, and Alkynes

(2012) Kanniyappan Parthasarathy et al.   ORGANIC LETTERS

Ruthenium(II)-Catalyzed Regio- and Stereoselective Hydroarylation of Alkynes via Directed C–H Functionalization

(2012) Yuto Hashimoto et al.   ORGANIC LETTERS

Highly Regio- and Stereoselective Ruthenium(II)-Catalyzed Direct ortho-Alkenylation of Aromatic and Heteroaromatic Aldehydes with Activated Alkenes under Open Atmosphere

(2012) Kishor Padala et al.   ORGANIC LETTERS

Versatile Pyrrole Synthesis through Ruthenium(II)-Catalyzed Alkene C–H Bond Functionalization on Enamines

(2012) Lianhui Wang et al.   ORGANIC LETTERS

Ruthenium-Catalyzed Highly Regioselective Cyclization of Ketoximes with Alkynes by C–H Bond Activation: A Practical Route to Synthesize Substituted Isoquinolines

(2012) Ravi Kiran Chinnagolla et al.   ORGANIC LETTERS

Ruthenium-catalyzed direct oxidative alkenylation of arenes through twofold C–H bond functionalization

(2012) Sergei I. Kozhushkov et al.   Chemical Science

Synthesis of Isoquinolines via Rhodium(III)-Catalyzed Dehydrative CC and CN Coupling between Oximines and Alkynes

(2011) Xingping Zhang et al.   ADVANCED SYNTHESIS & CATALYSIS

Removable Directing Groups in Organic Synthesis and Catalysis

(2011) Géraldine Rousseau et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Carbocyclization of Alkynyl Ketones Proceeding through a Carbopalladation Pathway

(2011) Natalia Chernyak et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regioselective Synthesis of Indenols by Rhodium-Catalyzed CH Activation and Carbocyclization of Aryl Ketones and Alkynes

(2011) Krishnamoorthy Muralirajan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ruthenium-Catalyzed Oxidative Annulation by Cleavage of CH/NH Bonds

(2011) Lutz Ackermann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pyridine synthesis from oximes and alkynesviarhodium(iii) catalysis: Cp* and Cptprovide complementary selectivity

(2011) Todd K. Hyster et al.   CHEMICAL COMMUNICATIONS

Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds

(2011) Charles S. Yeung et al.   CHEMICAL REVIEWS

Carboxylate-Assisted Transition-Metal-Catalyzed C−H Bond Functionalizations: Mechanism and Scope

(2011) Lutz Ackermann   CHEMICAL REVIEWS

Recent advances in the transition metal-catalyzed twofold oxidative C–H bond activation strategy for C–C and C–N bond formation

(2011) Seung Hwan Cho et al.   CHEMICAL SOCIETY REVIEWS

Pd-Catalyzed Multiple CH Functionalization to Construct Biologically Active Compounds from Aryl Aldoxime Ethers with Arenes

(2011) Vedhagiri S. Thirunavukkarasu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Ruthenium-Catalyzed Regioselective Cyclization of Aromatic Ketones with Alkynes: An Efficient Route to Indenols and Benzofulvenes

(2011) Ravi Kiran Chinnagolla et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Rhodium(III)-Catalyzed Oxidative Coupling of 5-Aryl-1H-pyrazoles with Alkynes and Acrylates

(2011) Xingwei Li et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Isochromene and Related Derivatives by Rhodium-Catalyzed Oxidative Coupling of Benzyl and Allyl Alcohols with Alkynes

(2011) Keisuke Morimoto et al.   JOURNAL OF ORGANIC CHEMISTRY

Diverse Strategies toward Indenol and Fulvene Derivatives: Rh-Catalyzed C−H Activation of Aryl Ketones Followed by Coupling with Internal Alkynes

(2011) Frederic W. Patureau et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silanol: A Traceless Directing Group for Pd-Catalyzedo-Alkenylation of Phenols

(2011) Chunhui Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Biphenyl-2-carbonitrile Derivatives via a Palladium-Catalyzed sp2C−H Bond Activation Using Cyano as a Directing Group

(2011) Wu Li et al.   ORGANIC LETTERS

Oxidative Coupling of Aromatic Substrates with Alkynes and Alkenes under Rhodium Catalysis

(2010) Tetsuya Satoh et al.   CHEMISTRY-A EUROPEAN JOURNAL

Functionalization of Organic Molecules by Transition-Metal-Catalyzed C(sp3)H Activation

(2010) Rodolphe Jazzar et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of Naphtho[1,8-bc]pyran Derivatives and Related Compounds through Hydroxy Group Directed CH Bond Cleavage under Rhodium Catalysis

(2010) Satoshi Mochida et al.   Chemistry-An Asian Journal

Pd(II)-Catalyzed Hydroxyl-Directed C−H Olefination Enabled by Monoprotected Amino Acid Ligands

(2010) Yi Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Phenanthrone Derivatives fromsec-Alkyl Aryl Ketones and Aryl Halides via a Palladium-Catalyzed Dual C−H Bond Activation and Enolate Cyclization

(2010) Parthasarathy Gandeepan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pyrrole Synthesis via Allylic sp3C−H Activation of Enamines Followed by Intermolecular Coupling with Unactivated Alkynes

(2010) Souvik Rakshit et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium(III)-Catalyzed Synthesis of Isoquinolines from Aryl KetoneO-Acyloxime Derivatives and Internal Alkynes

(2010) Pei Chui Too et al.   ORGANIC LETTERS

Synthesis of Fluorenesviathe Palladium-Catalyzed 5-exo-digAnnulation ofo-Alkynylbiaryls

(2009) Natalia Chernyak et al.   ADVANCED SYNTHESIS & CATALYSIS

Rhodium/N-Heterocyclic Carbene Catalyzed Direct Intermolecular Arylation of sp2and sp3CH Bonds with Chelation Assistance

(2009) Min Kim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

C−H Activation for the Construction of C−B Bonds

(2009) Ibraheem A. I. Mkhalid et al.   CHEMICAL REVIEWS

One-Pot Synthesis of Diarylmethylidenefluorenes and Phenanthrenes by Palladium-Catalyzed Multiple CH Bond Functionalization

(2009) Vedhagiri S. Thirunavukkarasu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Easy Access to Isoquinolines and Tetrahydroquinolines from Ketoximes and Alkynes via Rhodium-Catalyzed C−H Bond Activation

(2009) Kanniyappan Parthasarathy et al.   JOURNAL OF ORGANIC CHEMISTRY

Isoquinoline Synthesis via Rhodium-Catalyzed Oxidative Cross-Coupling/Cyclization of Aryl Aldimines and Alkynes

(2009) Nicolas Guimond et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Fluorenones from Aromatic Aldoxime Ethers and Aryl Halides by Palladium-Catalyzed Dual CH Activation and Heck Cyclization

(2008) Vedhagiri S. Thirunavukkarasu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium-catalysed anomalous dimerization of styrenes involving the cleavage of the ortho C–H bond

(2008) Mamoru Tobisu et al.   CHEMICAL COMMUNICATIONS

Exclusive 5-exo-digHydroarylation ofo-Alkynyl Biaryls Proceeding via C−H Activation Pathway

(2008) Natalia Chernyak et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Dihydropyridines and Pyridines from Imines and Alkynes via C−H Activation

(2008) Denise A. Colby et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An Efficient Low-Temperature Route to Polycyclic Isoquinoline Salt Synthesis via C−H Activation with [Cp*MCl2]2(M = Rh, Ir)

(2008) Ling Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium-Catalyzed One-Pot Synthesis of Substituted Pyridine Derivatives from α,β-Unsaturated Ketoximes and Alkynes

(2007) Kanniyappan Parthasarathy et al.   ORGANIC LETTERS