Inhibition of Bak Activation by VDAC2 Is Dependent on the Bak Transmembrane Anchor

Regulation of ceramide channels by Bcl-2 family proteins

(2010) Vidyaramanan Ganesan et al.   FEBS LETTERS

The BCL-2 Protein BAK Is Required for Long-chain Ceramide Generation during Apoptosis

(2010) Leah J. Siskind et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Tag at the Carboxy Terminus Prevents Membrane Integration of VDAC1 in Mammalian Mitochondria

(2010) Vera Kozjak-Pavlovic et al.   JOURNAL OF MOLECULAR BIOLOGY

TOM-independent complex formation of Bax and Bak in mammalian mitochondria during TNFα-induced apoptosis

(2009) K Ross et al.   CELL DEATH AND DIFFERENTIATION

VDAC2 is required for truncated BID-induced mitochondrial apoptosis by recruiting BAK to the mitochondria

(2009) Soumya Sinha Roy et al.   EMBO REPORTS

Bak Activation for Apoptosis Involves Oligomerization of Dimers via Their α6 Helices

(2009) Grant Dewson et al.   MOLECULAR CELL

Stepwise Activation of BAX and BAK by tBID, BIM, and PUMA Initiates Mitochondrial Apoptosis

(2009) Hyungjin Kim et al.   MOLECULAR CELL

The VDAC2-BAK Rheostat Controls Thymocyte Survival

(2009) D. Ren et al.   Science Signaling

The published 3D structure of the VDAC channel: native or not?

(2009) Marco Colombini   TRENDS IN BIOCHEMICAL SCIENCES

Analysis of endogenous Bax complexes during apoptosis using blue native PAGE: implications for Bax activation and oligomerization

(2008) Anthony J. Valentijn et al.   BIOCHEMICAL JOURNAL

Uncovering the role of VDAC in the regulation of cell life and death

(2008) Varda Shoshan-Barmatz et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Genetic strategies for dissecting mammalian and Drosophila voltage-dependent anion channel functions

(2008) William J. Craigen et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Structural and Functional Requirements for Activity of the Tim9–Tim10 Complex in Mitochondrial Protein Import

(2008) Michael J. Baker et al.   MOLECULAR BIOLOGY OF THE CELL

To Trigger Apoptosis, Bak Exposes Its BH3 Domain and Homodimerizes via BH3:Groove Interactions

(2008) Grant Dewson et al.   MOLECULAR CELL

Structure of the human voltage-dependent anion channel

(2008) M. Bayrhuber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The crystal structure of mouse VDAC1 at 2.3 A resolution reveals mechanistic insights into metabolite gating

(2008) R. Ujwal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Solution Structure of the Integral Human Membrane Protein VDAC-1 in Detergent Micelles

(2008) S. Hiller et al.   SCIENCE

Structural Plasticity Underpins Promiscuous Binding of the Prosurvival Protein A1

(2008) Callum Smits et al.   STRUCTURE

How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

(2008) Jerry E. Chipuk et al.   TRENDS IN CELL BIOLOGY

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY