Asymmetric synthesis of dihydrocoumarins via the organocatalytic hetero-Diels–Alder reaction of ortho-quinone methides

Asymmetric synthesis of chromene skeletons via organocatalytic domino reactions of in situ generated ortho-quinone methide with malononitrile and β-functionalized ketone

(2017) Lili Zhang et al.   RSC Advances

Asymmetric Synthesis of Dihydrocoumarins Containing Contiguous Quaternary and Tertiary Stereogenic Centers Catalyzed by aCinchona-Alkaloid-Based Bifunctional Thiourea Derivative

(2016) Shao-Yun Zhang et al.   ADVANCED SYNTHESIS & CATALYSIS

Stereocontrolled Construction of 3,4-Dihydrocoumarin Scaffolds with a Quaternary Amino Acid MoietyviaChiral Squaramide-Catalyzed Cascade Michael Addition/Lactonization Reaction

(2016) Yuehua Wang et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Asymmetric Inverse-Electron-Demand 1,3-Dipolar Cycloaddition of C,N-Cyclic Azomethine Imines with Azlactones: Access to Chiral Tricyclic Tetrahydroisoquinolines

(2016) Xihong Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Domino Oxa-Michael/1,6-Addition Reactions: Asymmetric Synthesis of Chromans Bearing Oxindole Scaffolds

(2016) Kun Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Cycloaddition of In Situ-Generated ortho -Quinone Methides and Azlactones by a Triple Brønsted Acid Activation Strategy

(2016) Xiao-Ye Yu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Catalytic Asymmetric Inverse-Electron-Demand Oxa-Diels-Alder Reaction of In Situ Generatedortho-Quinone Methides with 3-Methyl-2-Vinylindoles

(2015) Jia-Jia Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective synthesis of dihydrocoumarin derivatives by chiral scandium(iii)-complex catalyzed inverse-electron-demand hetero-Diels–Alder reaction

(2015) Haipeng Hu et al.   CHEMICAL COMMUNICATIONS

N-Heterocyclic carbene-catalyzed enantioselective annulations: a dual activation strategy for a formal [4+2] addition for dihydrocoumarins

(2015) Anna Lee et al.   CHEMICAL COMMUNICATIONS

Chiral Brønsted acid-catalyzed Friedel–Crafts alkylation of electron-rich arenes with in situ-generated ortho-quinone methides: highly enantioselective synthesis of diarylindolylmethanes and triarylmethanes

(2015) Satyajit Saha et al.   CHEMICAL COMMUNICATIONS

Catalytic Chemo-, E/Z-, and Enantioselective Cyclizations of o-Hydroxybenzyl Alcohols with Dimedone-Derived Enaminones

(2015) Jia-Jia Zhao et al.   JOURNAL OF ORGANIC CHEMISTRY

Regiodivergent Enantioselective γ-Additions of Oxazolones to 2,3-Butadienoates Catalyzed by Phosphines: Synthesis of α,α-Disubstituted α-Amino Acids and N,O-Acetal Derivatives

(2015) Tianli Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quinine-catalyzed highly enantioselective cycloannulation of o-quinone methides with malononitrile

(2015) Alafate Adili et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

C–H Oxidation/Michael Addition/Cyclization Cascade for Enantioselective Synthesis of Functionalized 2-Amino-4H-chromenes

(2015) Bo Wu et al.   ORGANIC LETTERS

Directing Group Assisted Nucleophilic Substitution of Propargylic Alcohols via o-Quinone Methide Intermediates: Brønsted Acid Catalyzed, Highly Enantio- and Diastereoselective Synthesis of 7-Alkynyl-12a-acetamido-Substituted Benzoxanthenes

(2015) Satyajit Saha et al.   ORGANIC LETTERS

Recent Advances in Chiral Phosphoric Acid Catalyzed Asymmetric Reactions for the Synthesis of Enantiopure Indole Derivatives

(2015) Hua Wu et al.   SYNTHESIS-STUTTGART

Enantio- and Diastereoselective Access to Distant Stereocenters Embedded within Tetrahydroxanthenes: Utilizingortho-Quinone Methides as Reactive Intermediates in Asymmetric Brønsted Acid Catalysis

(2014) Chien-Chi Hsiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Brønsted Acid Catalyzed, Conjugate Addition of β-Dicarbonyls to In Situ Generatedortho-Quinone Methides-Enantioselective Synthesis of 4-Aryl-4H-Chromenes

(2014) Osama El-Sepelgy et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Formation of All-Carbon Quaternary Stereocenters from Indoles and Tertiary Alcohols Bearing A Directing Group

(2014) Wanxiang Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diastereoselectivity in prebiotically relevant 5(4H)-oxazolone-mediated peptide couplings

(2014) Damien Beaufils et al.   CHEMICAL COMMUNICATIONS

An efficient strategy for the synthesis of polysubstituted chromeno[4,3-b]pyrrolidine derivatives

(2014) Li Tian et al.   CHEMICAL COMMUNICATIONS

Complete Field Guide to Asymmetric BINOL-Phosphate Derived Brønsted Acid and Metal Catalysis: History and Classification by Mode of Activation; Brønsted Acidity, Hydrogen Bonding, Ion Pairing, and Metal Phosphates

(2014) Dixit Parmar et al.   CHEMICAL REVIEWS

Brønsted Acid-Catalyzed, Highly Enantioselective Addition of Enamides to In Situ-Generatedortho-Quinone Methides: A Domino Approach to Complex Acetamidotetrahydroxanthenes

(2014) Satyajit Saha et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organocatalytic Asymmetric Synthesis of 1,1-Diarylethanes by Transfer Hydrogenation

(2014) Zhaobin Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Route to Dihydrocoumarins and Dihydroquinolinones in All Stereochemical Configurations

(2014) Oliver D. Engl et al.   ORGANIC LETTERS

Kinetic resolution of 4-substituted-3,4-dihydrocoumarins via Pd-catalyzed asymmetric allylic alkylation reaction: enantioselective synthesis of trans-3,4-disubstituted-3,4-dihydrocoumarins

(2014) Xiao-Hui Li et al.   Organic Chemistry Frontiers

N-Heterocyclic Carbene Catalyzed [4+3] Annulation of Enals ando-Quinone Methides: Highly Enantioselective Synthesis of Benzo-ε-Lactones

(2013) Hui Lv et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Diastereo- and Enantioselective 1,3-Dipolar Cycloaddition of Azlactones and Methyleneindolinones

(2013) Wangsheng Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective synthesis of 1,2,4-triazolines catalyzed by a cinchona alkaloid-derived organocatalyst

(2013) Qian Shao et al.   CHEMICAL COMMUNICATIONS

Recent Developments in Catalytic Asymmetric Inverse-Electron-Demand Diels–Alder Reaction

(2013) Xianxing Jiang et al.   CHEMICAL REVIEWS

Inverse electron demand Diels–Alder (iEDDA)-initiated conjugation: a (high) potential click chemistry scheme

(2013) Astrid-Caroline Knall et al.   CHEMICAL SOCIETY REVIEWS

A Dual Lewis Base Activation Strategy for Enantioselective Carbene-Catalyzed Annulations

(2013) Javier Izquierdo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Oxyamination of Azlactones: Kinetic Resolution of Oxaziridines and Asymmetric Synthesis of Oxazolin-4-ones

(2013) Shunxi Dong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dienamine-Mediated Inverse-Electron-Demand Hetero-Diels-Alder Reaction by Using an Enantioselective H-Bond-Directing Strategy

(2012) Łukasz Albrecht et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tandem inverse-electron-demand hetero-/retro-Diels–Alder reactions for aromatic nitrogen heterocycle synthesis

(2012) Radleigh A. A. Foster et al.   CHEMICAL SOCIETY REVIEWS

ortho-Quinone Methides in Natural Product Synthesis

(2012) Nicky J. Willis et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Addition of Boronates to o-Quinone Methides Catalyzed by Chiral Biphenols

(2012) Yi Luan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Benzylic Phosphates as Electrophiles in the Palladium-Catalyzed Asymmetric Benzylation of Azlactones

(2012) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Brønsted-Acid-Catalyzed Asymmetric Multicomponent Reactions for the Facile Synthesis of Highly Enantioenriched Structurally Diverse Nitrogenous Heterocycles

(2011) Jie Yu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Synthesis and biological evaluation of hydroxylated 3-phenylcoumarins as antioxidants and antiproliferative agents

(2011) Jie Yang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Oxazolones in Organocatalysis, New Tricks for an Old Reagent

(2011) Andrea-Nekane R. Alba et al.   Chemistry-An Asian Journal

Applications ofortho-Quinone Methide Intermediates in Catalysis and Asymmetric Synthesis

(2011) Tejas P. Pathak et al.   JOURNAL OF ORGANIC CHEMISTRY

Chiral Organic Contact Ion Pairs in Metal-Free Catalytic Asymmetric Allylic Substitutions

(2011) Magnus Rueping et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Conjugate Allylation of Coumarins

(2011) Yulong Kuang et al.   ORGANIC LETTERS

Asymmetric Synthesis of 3,4-Dihydrocoumarin Motif with an All-Carbon Quaternary Stereocenterviaa Michael–Acetalization Sequence with Bifunctional Amine-thiourea Organocatalysts

(2011) Bor-Cherng Hong et al.   ORGANIC LETTERS

Asymmetric Synthesis of 3,4-Diaminochroman-2-ones Promoted by Guanidine and Bisguanidium Salt

(2011) Shunxi Dong et al.   ORGANIC LETTERS

Aminocatalytic asymmetric inverse-electron-demand aza-Diels–Alder reaction of N-Ts-1-aza-1,3-butadienes based on coumarin cores

(2010) Jun-Long Li et al.   CHEMICAL COMMUNICATIONS

Chiral Bisguanidine-Catalyzed Inverse-Electron-Demand Hetero-Diels−Alder Reaction of Chalcones with Azlactones

(2010) Shunxi Dong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and Preliminary Biological Studies of 3-Substituted Indoles Accessed by a Palladium-Catalyzed Enantioselective Alkene Difunctionalization Reaction

(2010) Tejas P. Pathak et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Synthesis of DihydrocoumarinsviaN-Heterocyclic Carbene-Catalyzed Cycloaddition of Ketenes ando-Quinone Methides

(2009) Hui Lv et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric Synthesis of 3-Amino-δ-lactams and Benzo[a]quinolizidines by Catalytic Cyclization Reactions Involving Azlactones

(2009) Jun Jiang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Direct Aldol-Type Reaction of Azlactone via Protonation of Vinyl Ethers by a Chiral Brønsted Acid Catalyst

(2009) Masahiro Terada et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Novel 3-Carboxamide-coumarins as Potent and Selective FXIIa Inhibitors

(2008) Séverine Robert et al.   JOURNAL OF MEDICINAL CHEMISTRY

Chiral Tetraaminophosphonium Carboxylate-Catalyzed Direct Mannich-Type Reaction

(2008) Daisuke Uraguchi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Cycloadditions ofo-Quinone Methides Employing Chiral Ammonium Fluoride Precatalysts

(2008) Ethan Alden-Danforth et al.   ORGANIC LETTERS