Oncostatin M promotes cancer cell plasticity through cooperative STAT3-SMAD3 signaling
出版年份 2017 全文链接
标题
Oncostatin M promotes cancer cell plasticity through cooperative STAT3-SMAD3 signaling
作者
关键词
-
出版物
ONCOGENE
Volume 36, Issue 28, Pages 4001-4013
出版商
Springer Nature
发表日期
2017-03-14
DOI
10.1038/onc.2017.33
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Cancer Stem Cell Plasticity Drives Therapeutic Resistance
- (2016) Mary Doherty et al. Cancers
- Cancer Stem Cells: Targeting the Roots of Cancer, Seeds of Metastasis, and Sources of Therapy Resistance
- (2015) V. Adorno-Cruz et al. CANCER RESEARCH
- Cell-of-Origin of Cancer versus Cancer Stem Cells: Assays and Interpretations
- (2015) K. Rycaj et al. CANCER RESEARCH
- Therapeutic Implications of Cellular Heterogeneity and Plasticity in Breast Cancer
- (2015) Michael D. Brooks et al. Cell Stem Cell
- Oncostatin M and interleukin-31: Cytokines, receptors, signal transduction and physiology
- (2015) Heike M. Hermanns CYTOKINE & GROWTH FACTOR REVIEWS
- Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells
- (2015) Devon A. Lawson et al. NATURE
- STAT3 integrates cooperative Ras and TGF-β signals that induce Snail expression
- (2015) M Saitoh et al. ONCOGENE
- STAT3 selectively interacts with Smad3 to antagonize TGF-β
- (2015) G Wang et al. ONCOGENE
- Suppression of cancer relapse and metastasis by inhibiting cancer stemness
- (2015) Youzhi Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Temporally sequenced anticancer drugs overcome adaptive resistance by targeting a vulnerable chemotherapy-induced phenotypic transition
- (2015) Aaron Goldman et al. Nature Communications
- Short-term expansion of breast circulating cancer cells predicts response to anti-cancer therapy
- (2015) Bee Luan Khoo et al. Oncotarget
- Tumor Microenvironmental Signaling Elicits Epithelial-Mesenchymal Plasticity through Cooperation with Transforming Genetic Events
- (2015) Damian J. Junk et al. NEOPLASIA
- Stat3 signaling activation crosslinking of TGF-β1 in hepatic stellate cell exacerbates liver injury and fibrosis
- (2014) Ming-Yi Xu et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Drug Resistance via Feedback Activation of Stat3 in Oncogene-Addicted Cancer Cells
- (2014) Ho-June Lee et al. CANCER CELL
- Signaling pathway cooperation in TGF-β-induced epithelial–mesenchymal transition
- (2014) Rik Derynck et al. CURRENT OPINION IN CELL BIOLOGY
- Interleukin-6 (IL-6) Trans Signaling Drives a STAT3-dependent Pathway That Leads to Hyperactive Transforming Growth Factor-β (TGF-β) Signaling Promoting SMAD3 Activation and Fibrosis via Gremlin Protein
- (2014) Steven O'Reilly et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- HGF Induces Epithelial-to-Mesenchymal Transition by Modulating the Mammalian Hippo/MST2 and ISG15 Pathways
- (2014) Jennifer Farrell et al. JOURNAL OF PROTEOME RESEARCH
- SMAD7: a timer of tumor progression targeting TGF-β signaling
- (2014) Lingyu Luo et al. TUMOR BIOLOGY
- The Epithelial-Mesenchymal Transition Factor SNAIL Paradoxically Enhances Reprogramming
- (2014) Juli J. Unternaehrer et al. Stem Cell Reports
- HiJAK’d Signaling; the STAT3 Paradox in Senescence and Cancer Progression
- (2014) Damian Junk et al. Cancers
- Therapeutic targeting of the oncostatin M receptor-β prevents inflammatory heart failure
- (2013) Jochen Pöling et al. BASIC RESEARCH IN CARDIOLOGY
- Monocytes/macrophages support mammary tumor invasivity by co-secreting lineage-specific EGFR ligands and a STAT3 activator
- (2013) Philip Vlaicu et al. BMC CANCER
- The relevance of the TGF-β Paradox to EMT-MET programs
- (2013) Chevaun D. Morrison et al. CANCER LETTERS
- FOXC2 Expression Links Epithelial-Mesenchymal Transition and Stem Cell Properties in Breast Cancer
- (2013) B. G. Hollier et al. CANCER RESEARCH
- Poised Chromatin at the ZEB1 Promoter Enables Breast Cancer Cell Plasticity and Enhances Tumorigenicity
- (2013) Christine L. Chaffer et al. CELL
- TGF-β inhibition enhances chemotherapy action against triple-negative breast cancer
- (2013) Neil E. Bhola et al. JOURNAL OF CLINICAL INVESTIGATION
- Interleukin-6 and Oncostatin-M Synergize with the PI3K/AKT Pathway to Promote Aggressive Prostate Malignancy in Mouse and Human Tissues
- (2013) Daniel A. Smith et al. MOLECULAR CANCER RESEARCH
- Tumour heterogeneity and cancer cell plasticity
- (2013) Corbin E. Meacham et al. NATURE
- Oncostatin-M promotes phenotypic changes associated with mesenchymal and stem cell-like differentiation in breast cancer
- (2013) N R West et al. ONCOGENE
- Constitutive CCND1/CDK2 Activity Substitutes for p53 Loss, or MYC or Oncogenic RAS Expression in the Transformation of Human Mammary Epithelial Cells
- (2013) Damian J. Junk et al. PLoS One
- The MEK-ERK Pathway Is Necessary for Serine Phosphorylation of Mitochondrial STAT3 and Ras-Mediated Transformation
- (2013) Daniel J. Gough et al. PLoS One
- STAT3 activation in response to IL-6 is prolonged by the binding of IL-6 receptor to EGF receptor
- (2013) Y. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition
- (2013) M. Yu et al. SCIENCE
- Mesenchymal–epithelial transition (MET) as a mechanism for metastatic colonisation in breast cancer
- (2012) N. P. A. Devika Gunasinghe et al. CANCER AND METASTASIS REVIEWS
- EMT in carcinoma progression and dissemination: Facts, unanswered questions, and clinical considerations
- (2012) Jeremy Bastid CANCER AND METASTASIS REVIEWS
- Oncostatin M suppresses oestrogen receptor-α expression and is associated with poor outcome in human breast cancer
- (2012) Nathan R West et al. ENDOCRINE-RELATED CANCER
- Regulation of EMT by TGFβ in cancer
- (2012) Carl-Henrik Heldin et al. FEBS LETTERS
- Targeting Stat3 and Smad7 to restore TGF-β cytostatic regulation of tumor cells in vitro and in vivo
- (2012) R B Luwor et al. ONCOGENE
- TGF-β stimulates Pyk2 expression as part of an epithelial-mesenchymal transition program required for metastatic outgrowth of breast cancer
- (2012) M K Wendt et al. ONCOGENE
- Epithelial-mesenchymal transition and stemness features in circulating tumor cells from breast cancer patients
- (2011) Cristina Raimondi et al. BREAST CANCER RESEARCH AND TREATMENT
- Nonreceptor Tyrosine Kinase BMX Maintains Self-Renewal and Tumorigenic Potential of Glioblastoma Stem Cells by Activating STAT3
- (2011) Olga A. Guryanova et al. CANCER CELL
- c-MYC Functions as a Molecular Switch to Alter the Response of Human Mammary Epithelial Cells to Oncostatin M
- (2011) C. E. Kan et al. CANCER RESEARCH
- Cancer Stem Cells in Squamous Cell Carcinoma Switch between Two Distinct Phenotypes That Are Preferentially Migratory or Proliferative
- (2011) A. Biddle et al. CANCER RESEARCH
- The BMP2/7 heterodimer inhibits the human breast cancer stem cell subpopulation and bone metastases formation
- (2011) J T Buijs et al. ONCOGENE
- MiR-200b and miR-15b regulate chemotherapy-induced epithelial-mesenchymal transition in human tongue cancer cells by targeting BMI1
- (2011) L Sun et al. ONCOGENE
- Essential role of Stat3 in PI3K-induced oncogenic transformation
- (2011) Jonathan R. Hart et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TGF- signaling engages an ATM-CHK2-p53-independent RAS-induced senescence and prevents malignant transformation in human mammary epithelial cells
- (2011) R. Cipriano et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bone morphogenetic protein-10 (BMP-10) inhibits aggressiveness of breast cancer cells and correlates with poor prognosis in breast cancer
- (2010) Lin Ye et al. CANCER SCIENCE
- A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations
- (2010) Sreenath V. Sharma et al. CELL
- H3K27me3 regulates BMP activity in developing spinal cord
- (2010) N. Akizu et al. DEVELOPMENT
- Tumors as Organs: Complex Tissues that Interface with the Entire Organism
- (2010) Mikala Egeblad et al. DEVELOPMENTAL CELL
- Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes
- (2010) J. H. Taube et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nodal Signaling Recruits the Histone Demethylase Jmjd3 to Counteract Polycomb-Mediated Repression at Target Genes
- (2010) O. Dahle et al. Science Signaling
- Molecular Distinctions between Stasis and Telomere Attrition Senescence Barriers Shown by Long-term Culture of Normal Human Mammary Epithelial Cells
- (2009) J. C. Garbe et al. CANCER RESEARCH
- TGF-β-induced epithelial to mesenchymal transition
- (2009) Jian Xu et al. CELL RESEARCH
- Mechanisms of the epithelial–mesenchymal transition by TGF-β
- (2009) Michael K Wendt et al. Future Oncology
- Interleukin-6 induces an epithelial–mesenchymal transition phenotype in human breast cancer cells
- (2009) N J Sullivan et al. ONCOGENE
- Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features
- (2009) C. J. Creighton et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cancer and the tumor microenvironment: a review of an essential relationship
- (2008) Flaubert Mbeunkui et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Inhibition of STAT3Tyr705 Phosphorylation by Smad4 Suppresses Transforming Growth Factor -Mediated Invasion and Metastasis in Pancreatic Cancer Cells
- (2008) S. Zhao et al. CANCER RESEARCH
- The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
- (2008) Sendurai A. Mani et al. CELL
- Phospho-control of TGF-β superfamily signaling
- (2008) Katharine H Wrighton et al. CELL RESEARCH
- Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis
- (2008) Jing Yang et al. DEVELOPMENTAL CELL
- Intrinsic Resistance of Tumorigenic Breast Cancer Cells to Chemotherapy
- (2008) X. Li et al. JNCI-Journal of the National Cancer Institute
- Stromal gene expression predicts clinical outcome in breast cancer
- (2008) Greg Finak et al. NATURE MEDICINE
- Smad7 is inactivated through a direct physical interaction with the LIM protein Hic-5/ARA55
- (2008) H Wang et al. ONCOGENE
- Generation of Breast Cancer Stem Cells through Epithelial-Mesenchymal Transition
- (2008) Anne-Pierre Morel et al. PLoS One
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started