Enteroendocrine cells-sensory sentinels of the intestinal environment and orchestrators of mucosal immunity

A whole animal chemical screen approach to identify modifiers of intestinal neutrophilic inflammation

(2017) Stefan H. Oehlers et al.   FEBS Journal

Vagal Regulation of Group 3 Innate Lymphoid Cells and the Immunoresolvent PCTR1 Controls Infection Resolution

(2017) Jesmond Dalli et al.   IMMUNITY

Safety and Efficacy of Teduglutide (Gattex) in Patients With Crohn’s Disease and Need for Parenteral Support Due to Short Bowel Syndrome–associated Intestinal Failure

(2017) Bharati Kochar et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

GLP-1 nanomedicine alleviates gut inflammation

(2017) Arivarasu N. Anbazhagan et al.   Nanomedicine-Nanotechnology Biology and Medicine

Leptin in the interplay of inflammation, metabolism and immune system disorders

(2017) Vanessa Abella et al.   Nature Reviews Rheumatology

Enteroviruses infect human enteroids and induce antiviral signaling in a cell lineage-specific manner

(2017) Coyne G. Drummond et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Somatostatin regulates NHE8 protein expression via the ERK1/2 MAPK pathway in DSS-induced colitis mice

(2016) Xiao Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Enteroendocrine Cells: Chemosensors in the Intestinal Epithelium

(2016) Fiona M. Gribble et al.   Annual Review of Physiology

The pro-inflammatory cytokines IFN /TNF  increase chromogranin A-positive neuroendocrine cells in the colonic epithelium

(2016) J. A. Hernandez-Trejo et al.   BIOCHEMICAL JOURNAL

Opposing Effects of Fasting Metabolism on Tissue Tolerance in Bacterial and Viral Inflammation

(2016) Andrew Wang et al.   CELL

iNKT Cells Induce FGF21 for Thermogenesis and Are Required for Maximal Weight Loss in GLP1 Therapy

(2016) Lydia Lynch et al.   Cell Metabolism

Gut Commensal E. coli Proteins Activate Host Satiety Pathways following Nutrient-Induced Bacterial Growth

(2016) Jonathan Breton et al.   Cell Metabolism

Neurotensin Is Coexpressed, Coreleased, and Acts Together With GLP-1 and PYY in Enteroendocrine Control of Metabolism

(2016) Kaare V. Grunddal et al.   ENDOCRINOLOGY

The Microbiome, Timing, and Barrier Function in the Context of Allergic Disease

(2016) Duane R. Wesemann et al.   IMMUNITY

GLP-1 Induces Barrier Protective Expression in Brunnerʼs Glands and Regulates Colonic Inflammation

(2016) Claus H. Bang-Berthelsen et al.   INFLAMMATORY BOWEL DISEASES

Evolving Concepts and Translational Relevance of Enteroendocrine Cell Biology

(2016) Daniel J. Drucker   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The intestinal cholinergic anti-inflammatory pathway

(2016) Gera Goverse et al.   JOURNAL OF PHYSIOLOGY-LONDON

Differential effects of GLP-1 receptor agonist on foam cell formation in monocytes between non-obese and obese subjects

(2016) Masashi Tanaka et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Effects of AP-1 and NF-κB inhibitors on colonic endocrine cells in rats with TNBS-induced colitis

(2016) Magdy El-Salhy et al.   Molecular Medicine Reports

Changes in enteroendocrine and immune cells following colitis induction by TNBS in rats

(2016) Magdy El-Salhy et al.   Molecular Medicine Reports

Mechanisms of inflammation-driven bacterial dysbiosis in the gut

(2016) M Y Zeng et al.   Mucosal Immunology

Intestinal epithelial tuft cells initiate type 2 mucosal immunity to helminth parasites

(2016) François Gerbe et al.   NATURE

Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut

(2016) M. R. Howitt et al.   SCIENCE

Tuft Cells: A New Flavor in Innate Epithelial Immunity

(2016) Richard K. Grencis et al.   TRENDS IN PARASITOLOGY

Brachyury identifies a class of enteroendocrine cells in normal human intestinal crypts and colorectal cancer

(2016) Jana Jezkova et al.   Oncotarget

Programming of Intestinal Epithelial Differentiation by IL-33 Derived from Pericryptal Fibroblasts in Response to Systemic Infection

(2016) Mousumi Mahapatro et al.   Cell Reports

How gut microbes talk to organs: The role of endocrine and nervous routes

(2016) Patrice D. Cani et al.   Molecular Metabolism

Effects of glucagon-like peptide-2 on bacterial translocation in rat models of colitis

(2016) Bulent HALACLAR et al.   Turkish Journal of Gastroenterology

Tumor Necrosis Factor α Decreases Glucagon-Like Peptide-2 Expression by Up-Regulating G-Protein–Coupled Receptor 120 in Crohn Disease

(2015) Takuya Tsukahara et al.   AMERICAN JOURNAL OF PATHOLOGY

Nkx2.2 is expressed in a subset of enteroendocrine cells with expanded lineage potential

(2015) Stefanie Gross et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

GLP-1R Agonists Promote Normal and Neoplastic Intestinal Growth through Mechanisms Requiring Fgf7

(2015) Jacqueline A. Koehler et al.   Cell Metabolism

GLP-1R Agonists Modulate Enteric Immune Responses Through the Intestinal Intraepithelial Lymphocyte GLP-1R

(2015) Bernardo Yusta et al.   DIABETES

The MicroRNA Repertoire in Enteroendocrine Cells: Identification of miR-375 as a Potential Regulator of the Enteroendocrine Lineage

(2015) Lina A. Knudsen et al.   ENDOCRINOLOGY

Bile Acids Trigger GLP-1 Release Predominantly by Accessing Basolaterally Located G Protein–Coupled Bile Acid Receptors

(2015) Cheryl A. Brighton et al.   ENDOCRINOLOGY

A Transcriptome-Led Exploration of Molecular Mechanisms Regulating Somatostatin-Producing D-Cells in the Gastric Epithelium

(2015) Alice Adriaenssens et al.   ENDOCRINOLOGY

An Analysis of Cosecretion and Coexpression of Gut Hormones From Male Rat Proximal and Distal Small Intestine

(2015) Berit Svendsen et al.   ENDOCRINOLOGY

Gastric emptying and disease activity in inflammatory bowel disease

(2015) Jutta Keller et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Gut chemosensing mechanisms

(2015) Arianna Psichas et al.   JOURNAL OF CLINICAL INVESTIGATION

Neuroepithelial circuit formed by innervation of sensory enteroendocrine cells

(2015) Diego V. Bohórquez et al.   JOURNAL OF CLINICAL INVESTIGATION

Carcinoid and Neuroendocrine Tumors: Building on Success

(2015) Pamela L. Kunz   JOURNAL OF CLINICAL ONCOLOGY

Increase in plasma acyl ghrelin levels is associated with abatement of dyspepsia following Helicobacter pylori eradication

(2015) Yoon Jin Choi et al.   JOURNAL OF GASTROENTEROLOGY

Research Resource: A Chromogranin A Reporter for Serotonin and Histamine Secreting Enteroendocrine Cells

(2015) Maja S. Engelstoft et al.   MOLECULAR ENDOCRINOLOGY

Tuft-cell-derived IL-25 regulates an intestinal ILC2–epithelial response circuit

(2015) Jakob von Moltke et al.   NATURE

Ghrelin Inhibits the Differentiation of T Helper 17 Cells through mTOR/STAT3 Signaling Pathway

(2015) Yanhui Xu et al.   PLoS One

Somatostatin Improved B Cells Mature in Macaques during Intestinal Ischemia-Reperfusion

(2015) Ling Liu et al.   PLoS One

Glucagon-like peptide-2 protects impaired intestinal mucosal barriers in obstructive jaundice rats

(2015) Jun Chen   WORLD JOURNAL OF GASTROENTEROLOGY

Neuroendocrine differentiation: The mysterious fellow of colorectal cancer

(2015) Britta Kleist   WORLD JOURNAL OF GASTROENTEROLOGY

The Drosophila Prosecretory Transcription Factor dimmed Is Dynamically Regulated in Adult Enteroendocrine Cells and Protects Against Gram-Negative Infection

(2015) Katherine Beebe et al.   G3-Genes Genomes Genetics

Isolation of Human Colon Stem Cells Using Surface Expression of PTK7

(2015) Peter Jung et al.   Stem Cell Reports

Chronic Trichuris muris Infection in C57BL/6 Mice Causes Significant Changes in Host Microbiota and Metabolome: Effects Reversed by Pathogen Clearance

(2015) Ashley Houlden et al.   PLoS One

The role of serotonin and its receptors in activation of immune responses and inflammation

(2014) M. S. Shajib et al.   Acta Physiologica

Increase in Neuroendocrine Cells in the Duodenal Mucosa of Patients with Refractory Celiac Disease

(2014) Antonio Di Sabatino et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Impaired enteroendocrine development in intestinal-specific Islet1 mouse mutants causes impaired glucose homeostasis

(2014) Natalie A. Terry et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

A phase I trial of everolimus in combination with 5-FU/LV, mFOLFOX6 and mFOLFOX6 plus panitumumab in patients with refractory solid tumors

(2014) Autumn J. McRee et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

GLP-2 Suppresses LPS-Induced Inflammation in Macrophages by Inhibiting ERK Phosphorylation and NF-κB Activation

(2014) Shanshan Xie et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Ghrelin augments murine T-cell proliferation by activation of the phosphatidylinositol-3-kinase, extracellular signal-regulated kinase and protein kinase C signaling pathways

(2014) Jun Ho Lee et al.   FEBS LETTERS

Cholecystokinin octapeptide regulates the differentiation and effector cytokine production of CD4+ T cells in vitro

(2014) Jing-Ge Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The short chain fatty acid propionate stimulates GLP-1 and PYY secretion via free fatty acid receptor 2 in rodents

(2014) A Psichas et al.   INTERNATIONAL JOURNAL OF OBESITY

The ghrelin-positive cells number is increased in duodenum in children with celiac disease

(2014) E. Jarocka-Cyrta et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Ghrelin Protects against Experimental Sepsis by Inhibiting High-Mobility Group Box 1 Release and by Killing Bacteria

(2014) A. Chorny et al.   JOURNAL OF IMMUNOLOGY

Long-Acting Glucose-Dependent Insulinotropic Polypeptide Ameliorates Obesity-Induced Adipose Tissue Inflammation

(2014) Chen Varol et al.   JOURNAL OF IMMUNOLOGY

Cholecystokinin Inhibits Inducible Nitric Oxide Synthase Expression by Lipopolysaccharide-Stimulated Peritoneal Macrophages

(2014) Rafael Simone Saia et al.   MEDIATORS OF INFLAMMATION

Intestinal neuroendocrine cells and goblet cells are mediators of IL-17A-amplified epithelial IL-17C production in human inflammatory bowel disease

(2014) M Friedrich et al.   Mucosal Immunology

An Enteroendocrine Cell – Enteric Glia Connection Revealed by 3D Electron Microscopy

(2014) Diego V. Bohórquez et al.   PLoS One

Enteroendocrine Cells Are Specifically Marked by Cell Surface Expression of Claudin-4 in Mouse Small Intestine

(2014) Takahiro Nagatake et al.   PLoS One

Chromogranin A as a biomarker of disease activity and biologic therapy in inflammatory bowel disease: a prospective observational study

(2014) Athanasios Zissimopoulos et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Adult Stem Cells in the Small Intestine Are Intrinsically Programmed with Their Location-Specific Function

(2014) Sabine Middendorp et al.   STEM CELLS

Human enteroendocrine cell responses to infection with Chlamydia trachomatis: a microarray study

(2014) Aldona Dlugosz et al.   Gut Pathogens

Enteroendocrine Cells Support Intestinal Stem-Cell-Mediated Homeostasis in Drosophila

(2014) Alla Amcheslavsky et al.   Cell Reports

Bacterial Metabolite Indole Modulates Incretin Secretion from Intestinal Enteroendocrine L Cells

(2014) Catalin Chimerel et al.   Cell Reports

Lipid-rich enteral nutrition regulates mucosal mast cell activation via the vagal anti-inflammatory reflex

(2013) Jacco J. de Haan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Reprogramming of enteroendocrine K cells to pancreatic β-cells through the combined expression of Nkx6.1 and Neurogenin3, and reaggregation in suspension culture

(2013) Esder Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Therapeutic effect of ghrelin in experimental autoimmune encephalomyelitis by inhibiting antigen-specific Th1/Th17 responses and inducing regulatory T cells

(2013) Luciana Souza-Moreira et al.   BRAIN BEHAVIOR AND IMMUNITY

Phase 1 and pharmacodynamic trial of everolimus in combination with cetuximab in patients with advanced cancer

(2013) Christine A. Ciunci et al.   CANCER

CCK1-Receptor Stimulation Protects Against Gut Mediator-Induced Lung Damage During Endotoxemia

(2013) Friederike Eisner et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Enteroendocrine cells in gastrointestinal pathophysiology

(2013) Elizabeth Harrison et al.   CURRENT OPINION IN PHARMACOLOGY

Gut microbiota, enteroendocrine functions and metabolism

(2013) Patrice D Cani et al.   CURRENT OPINION IN PHARMACOLOGY

Lipopolysaccharides-Mediated Increase in Glucose-Stimulated Insulin Secretion: Involvement of the GLP-1 Pathway

(2013) A. T. Nguyen et al.   DIABETES

Glucagon-like peptide 1 analogue therapy directly modulates innate immune-mediated inflammation in individuals with type 2 diabetes mellitus

(2013) Andrew E. Hogan et al.   DIABETOLOGIA

Oligopeptides stimulate glucagon-like peptide-1 secretion in mice through proton-coupled uptake and the calcium-sensing receptor

(2013) Eleftheria Diakogiannaki et al.   DIABETOLOGIA

GPR41/FFAR3 and GPR43/FFAR2 as Cosensors for Short-Chain Fatty Acids in Enteroendocrine Cells vs FFAR3 in Enteric Neurons and FFAR2 in Enteric Leukocytes

(2013) Mark K. Nøhr et al.   ENDOCRINOLOGY

The Intestinal Epithelial Insulin-Like Growth Factor-1 Receptor Links Glucagon-Like Peptide-2 Action to Gut Barrier Function

(2013) Charlotte X. Dong et al.   ENDOCRINOLOGY

Incretins, amylin and other gut-brain axis hormones in children with coeliac disease

(2013) Maria Papastamataki et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

CCK8 negatively regulates the TLR9-induced activation of human peripheral blood pDCs by targeting TRAF6 signaling

(2013) Xianxian Jia et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Alterations in mucosal neuropeptides in patients with irritable bowel syndrome and ulcerative colitis in remission: A role in pain symptom generation?

(2013) D. Keszthelyi et al.   EUROPEAN JOURNAL OF PAIN

A distinct vagal anti-inflammatory pathway modulates intestinal muscularis resident macrophages independent of the spleen

(2013) Gianluca Matteoli et al.   GUT

Increased Fecal Levels of Chromogranin A, Chromogranin B, and Secretoneurin in Collagenous Colitis

(2013) Michael Wagner et al.   INFLAMMATION

The genomic landscape of small intestine neuroendocrine tumors

(2013) Michaela S. Banck et al.   JOURNAL OF CLINICAL INVESTIGATION

Fecal chromogranins and secretogranins are increased in patients with ulcerative colitis but are not associated with disease activity

(2013) Hans Strid et al.   Journal of Crohns & Colitis

Anti-inflammatory Effect of Obestatin and Ghrelin in Dextran Sulfate Sodium–Induced Colitis in Rats

(2013) Ozge Pamukcu et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Intestinal label-retaining cells are secretory precursors expressing Lgr5

(2013) Simon J. A. Buczacki et al.   NATURE

The endocrinology of food intake

(2013) Denovan P. Begg et al.   Nature Reviews Endocrinology

Adult intestinal stem cells: critical drivers of epithelial homeostasis and regeneration

(2013) Nick Barker   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Gastrointestinal Viral Load and Enteroendocrine Cell Number Are Associated with Altered Survival in HIV-1 Infected Individuals

(2013) Guido van Marle et al.   PLoS One

Lymphocyte-derived ACh regulates local innate but not adaptive immunity

(2013) Colin Reardon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anti-inflammatory effects of exendin-4, a glucagon-like peptide-1 analog, on human peripheral lymphocytes in patients with type 2 diabetes

(2013) Lan He et al.   Journal of Diabetes Investigation

Adaptive Immunity Alters Distinct Host Feeding Pathways during Nematode Induced Inflammation, a Novel Mechanism in Parasite Expulsion

(2013) John J. Worthington et al.   PLoS Pathogens

Central Role of the Gut Epithelial Barrier in the Pathogenesis of Chronic Intestinal Inflammation: Lessons Learned from Animal Models and Human Genetics

(2013) Luca Pastorelli et al.   Frontiers in Immunology

Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells

(2013) Maja S. Engelstoft et al.   Molecular Metabolism

Cellular bases for interactions between immunocytes and enteroendocrine cells in the intestinal mucosal barrier of rhesus macaques

(2012) Wen-Jun Zhang et al.   CELL AND TISSUE RESEARCH

Crohn's disease affecting the small bowel is associated with reduced appetite and elevated levels of circulating gut peptides

(2012) Gordon W. Moran et al.   CLINICAL NUTRITION

Impaired MEK Signaling and SERCA Expression Promote ER Stress and Apoptosis in Insulin-Resistant Macrophages and Are Reversed by Exenatide Treatment

(2012) C.-P. Liang et al.   DIABETES

Cholecystokinin Plays a Novel Protective Role in Diabetic Kidney Through Anti-inflammatory Actions on Macrophage: Anti-inflammatory Effect of Cholecystokinin

(2012) S. Miyamoto et al.   DIABETES

Disruption of the MurineGlp2rImpairs Paneth Cell Function and Increases Susceptibility to Small Bowel Enteritis

(2012) Seung-Jun Lee et al.   ENDOCRINOLOGY

A Major Lineage of Enteroendocrine Cells Coexpress CCK, Secretin, GIP, GLP-1, PYY, and Neurotensin but Not Somatostatin

(2012) Kristoffer L. Egerod et al.   ENDOCRINOLOGY

Overlap of Endocrine Hormone Expression in the Mouse Intestine Revealed by Transcriptional Profiling and Flow Cytometry

(2012) Abdella M. Habib et al.   ENDOCRINOLOGY

FGF21 Is Increased by Inflammatory Stimuli and Protects Leptin-Deficientob/obMice from the Toxicity of Sepsis

(2012) Kenneth R. Feingold et al.   ENDOCRINOLOGY

The vagal innervation of the gut and immune homeostasis

(2012) Gianluca Matteoli et al.   GUT

Enteroendocrine cells in terminal ileal Crohn's disease

(2012) Gordon W. Moran et al.   Journal of Crohns & Colitis

Differential Expression of Neurotensin and Specific Receptors, NTSR1 and NTSR2, in Normal and Malignant Human B Lymphocytes

(2012) S. Saada et al.   JOURNAL OF IMMUNOLOGY

Peyer's Patch M Cells Derived from Lgr5+ Stem Cells Require SpiB and Are Induced by RankL in Cultured "Miniguts"

(2012) W. de Lau et al.   MOLECULAR AND CELLULAR BIOLOGY

The Ets transcription factor Spi-B is essential for the differentiation of intestinal microfold cells

(2012) Takashi Kanaya et al.   NATURE IMMUNOLOGY

Nesfatin-1, a unique regulatory neuropeptide of the brain

(2012) Artur Pałasz et al.   NEUROPEPTIDES

Butyrate and Propionate Protect against Diet-Induced Obesity and Regulate Gut Hormones via Free Fatty Acid Receptor 3-Independent Mechanisms

(2012) Hua V. Lin et al.   PLoS One

Duodenal Enteroendocrine I-Cells Contain mRNA Transcripts Encoding Key Endocannabinoid and Fatty Acid Receptors

(2012) Alexandros G. Sykaras et al.   PLoS One

GLP-2 enhances barrier formation and attenuates TNFα-induced changes in a Caco-2 cell model of the intestinal barrier

(2012) G.W. Moran et al.   REGULATORY PEPTIDES

High densities of serotonin and peptide YY cells in the colon of patients with lymphocytic colitis

(2012) Magdy El-Salhy   WORLD JOURNAL OF GASTROENTEROLOGY

Gut bitter taste receptor signalling induces ABCB1 through a mechanism involving CCK

(2011) Tae-Il Jeon et al.   BIOCHEMICAL JOURNAL

Neurotensin downregulates the pro-inflammatory properties of skin dendritic cells and increases epidermal growth factor expression

(2011) Lucília da Silva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Cholecystokinin octapeptide significantly suppresses collagen-induced arthritis in mice by inhibiting Th17 polarization primed by dendritic cells

(2011) Qiaoxia Li et al.   CELLULAR IMMUNOLOGY

Na+-D-glucose Cotransporter SGLT1 is Pivotal for Intestinal Glucose Absorption and Glucose-Dependent Incretin Secretion

(2011) V. Gorboulev et al.   DIABETES

Short-Chain Fatty Acids Stimulate Glucagon-Like Peptide-1 Secretion via the G-Protein-Coupled Receptor FFAR2

(2011) G. Tolhurst et al.   DIABETES

Responses of Gut Microbiota and Glucose and Lipid Metabolism to Prebiotics in Genetic Obese and Diet-Induced Leptin-Resistant Mice

(2011) Amandine Everard et al.   DIABETES

Basic helix-loop-helix transcription factors and enteroendocrine cell differentiation

(2011) H. J. Li et al.   DIABETES OBESITY & METABOLISM

Glucagon-like peptide-1 (GLP-1) and the regulation of human invariant natural killer T cells: lessons from obesity, diabetes and psoriasis

(2011) A. E. Hogan et al.   DIABETOLOGIA

GATA Factors Regulate Proliferation, Differentiation, and Gene Expression in Small Intestine of Mature Mice

(2011) Eva Beuling et al.   GASTROENTEROLOGY

Regulation of the immune response and inflammation by histamine and histamine receptors

(2011) Liam O’Mahony et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Distinct ATOH1 and Neurog3 requirements define tuft cells as a new secretory cell type in the intestinal epithelium

(2011) François Gerbe et al.   JOURNAL OF CELL BIOLOGY

Topical Cholecystokinin Depresses Itch-Associated Scratching Behavior in Mice

(2011) Shoko Fukamachi et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Chylomicron formation and glucagon-like peptide 1 receptor are involved in activation of the nutritional anti-inflammatory pathway

(2011) Tim Lubbers et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Leptin as an immunomodulator

(2011) Claudio Procaccini et al.   MOLECULAR ASPECTS OF MEDICINE

Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells

(2011) Helga Ellingsgaard et al.   NATURE MEDICINE

Endocrine impact of Helicobacter pylori: Focus on ghrelin and ghrelin o-acyltransferase

(2011) Penny L Jeffery   WORLD JOURNAL OF GASTROENTEROLOGY

Rotavirus Stimulates Release of Serotonin (5-HT) from Human Enterochromaffin Cells and Activates Brain Structures Involved in Nausea and Vomiting

(2011) Marie Hagbom et al.   PLoS Pathogens

Chlamydia trachomatis antigens in enteroendocrine cells and macrophages of the small bowel in patients with severe irritable bowel syndrome

(2010) Aldona Dlugosz et al.   BMC GASTROENTEROLOGY

Hepatocyte nuclear factor 1  and   control terminal differentiation and cell fate commitment in the gut epithelium

(2010) A. D'Angelo et al.   DEVELOPMENT

Cdx2 regulates patterning of the intestinal epithelium

(2010) Stephanie Grainger et al.   DEVELOPMENTAL BIOLOGY

Inhibition of Monocyte Adhesion to Endothelial Cells and Attenuation of Atherosclerotic Lesion by a Glucagon-like Peptide-1 Receptor Agonist, Exendin-4

(2010) M. Arakawa et al.   DIABETES

Glucagon-like peptide-1 receptor signalling selectively regulates murine lymphocyte proliferation and maintenance of peripheral regulatory T cells

(2010) I. Hadjiyanni et al.   DIABETOLOGIA

The G-Protein−Coupled Receptor GPR40 Directly Mediates Long-Chain Fatty Acid−Induced Secretion of Cholecystokinin

(2010) Alice P. Liou et al.   GASTROENTEROLOGY

Cholecystokinin octapeptide regulates lipopolysaccharide-activated B cells co-stimulatory molecule expression and cytokines production in vitro

(2010) Jing-Ge Zhang et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Loss of enteroendocrine cells in mice alters lipid absorption and glucose homeostasis and impairs postnatal survival

(2010) Georg Mellitzer et al.   JOURNAL OF CLINICAL INVESTIGATION

Characterization of basal pseudopod-like processes in ileal and colonic PYY cells

(2010) Diego V. Bohórquez et al.   JOURNAL OF MOLECULAR HISTOLOGY

Ghrelin promotes nuclear factor kappa-B activation in a human B-lymphocyte cell line

(2010) E. Z. H. Sung et al.   MOLECULAR BIOLOGY REPORTS

Ghrelin and obestatin promote the allergic action in rat peritoneal mast cells as basic secretagogues

(2010) Tatsuya Hirayama et al.   PEPTIDES

Loss of Hepatocyte-Nuclear-Factor-1α Impacts on Adult Mouse Intestinal Epithelial Cell Growth and Cell Lineages Differentiation

(2010) Carine R. Lussier et al.   PLoS One

Weight loss during oligofructose supplementation is associated with decreased ghrelin and increased peptide YY in overweight and obese adults

(2009) Jill A Parnell et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Gut microbiota fermentation of prebiotics increases satietogenic and incretin gut peptide production with consequences for appetite sensation and glucose response after a meal

(2009) Patrice D Cani et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Mechanisms of gastric emptying disturbances in chronic and acute inflammation of the distal gastrointestinal tract

(2009) Jutta Keller et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Lipid-Rich Enteral Nutrition Reduces Postoperative Ileus in Rats via Activation of Cholecystokinin-Receptors

(2009) Tim Lubbers et al.   ANNALS OF SURGERY

Reduction of T cell-derived ghrelin enhances proinflammatory cytokine expression: implications for age-associated increases in inflammation

(2009) V. D. Dixit et al.   BLOOD

Leptin: A Critical Regulator of CD4+T-cell Polarizationin Vitroandin Vivo

(2009) Arvind Batra et al.   ENDOCRINOLOGY

Current perspective: Bevacizumab in colorectal cancer – A time for reappraisal?

(2009) Alicia Okines et al.   EUROPEAN JOURNAL OF CANCER

ErbB Signaling Is Required for the Proliferative Actions of GLP-2 in the Murine Gut

(2009) Bernardo Yusta et al.   GASTROENTEROLOGY

Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability

(2009) P. D. Cani et al.   GUT

RANKL Is Necessary and Sufficient to Initiate Development of Antigen-Sampling M Cells in the Intestinal Epithelium

(2009) K. A. Knoop et al.   JOURNAL OF IMMUNOLOGY

Ghrelin and obestatin modulate early atherogenic processes on cells: enhancement of monocyte adhesion and oxidized low-density lipoprotein binding

(2009) Eija Kellokoski et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Gut endocrine cell development

(2009) Catherine Lee May et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

IL1β- and LPS-induced serotonin secretion is increased in EC cells derived from Crohn’s disease

(2009) m. kidd et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Chemotherapy with Targeted Agents for the Treatment of Metastatic Colorectal Cancer

(2009) C.-H. Kohne et al.   ONCOLOGIST

Characterization of a novel ghrelin cell reporter mouse

(2009) Ichiro Sakata et al.   REGULATORY PEPTIDES

Associations between blood gastrin, ghrelin, leptin, pepsinogen and Ostertagia ostertagi antibody concentrations and voluntary feed intake in calves exposed to a trickle infection with O. ostertagi

(2009) A.B. Forbes et al.   VETERINARY PARASITOLOGY

The Role of Anorexia in Resistance and Tolerance to Infections in Drosophila

(2009) Janelle S. Ayres et al.   PLOS BIOLOGY

Interleukin-10-independent anti-inflammatory actions of glucagon-like peptide 2

(2008) Catherine P. A. Ivory et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Neuropeptides kill African trypanosomes by targeting intracellular compartments and inducing autophagic-like cell death

(2008) M Delgado et al.   CELL DEATH AND DIFFERENTIATION

Glucose Sensing in L Cells: A Primary Cell Study

(2008) Frank Reimann et al.   Cell Metabolism

Nutrient-dependent secretion of glucose-dependent insulinotropic polypeptide from primary murine K cells

(2008) H. E. Parker et al.   DIABETOLOGIA

Phenotypical and functional study of ghrelin and its receptor in the pathogenesis of Crohnʼs disease

(2008) Shuhei Hosomi et al.   INFLAMMATORY BOWEL DISEASES

Immunoreactivity against goblet cells in patients with inflammatory bowel disease

(2008) Brita Ardesjö et al.   INFLAMMATORY BOWEL DISEASES

Plasma chromogranin a in patients with inflammatory bowel disease

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Induction of pro-inflammatory programs in enteroendocrine cells by the Toll-like receptor agonists flagellin and bacterial LPS

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Chromogranin A-, serotonin-, synaptophysin- and vascular endothelial growth factor-positive endocrine cells and the prognosis of colorectal cancer: An immunohistochemical and ultrastructural study

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The intestinal epithelium: sensors to effectors in nematode infection

(2008) D Artis et al.   Mucosal Immunology

Tissue ghrelin level and gastric emptying rate in adult patients with celiac disease

(2008) a. rocco et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Orexigenic Hormone Ghrelin Attenuates Local and Remote Organ Injury after Intestinal Ischemia-Reperfusion

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Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41

(2008) B. S. Samuel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Changes of the Peptide YY Levels in the Intestinal Tissue of Rats with Experimental Colitis following Oral Administration of Mesalazine and Prednisolone

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Review: Enteroendocrine cells: Neglected players in gastrointestinal disorders?

(2008) Gordon W. Moran et al.   Therapeutic Advances in Gastroenterology

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Autoantibodies against ubiquitination factor E4A (UBE4A) are associated with severity of Crohnʼs disease

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