标题
Autotaxin-Lysophosphatidic Acid: From Inflammation to Cancer Development
作者
关键词
-
出版物
MEDIATORS OF INFLAMMATION
Volume 2017, Issue -, Pages 1-15
出版商
Hindawi Limited
发表日期
2017-12-22
DOI
10.1155/2017/9173090
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Lysophosphatidic acid signaling via LPA1 and LPA3 regulates cellular functions during tumor progression in pancreatic cancer cells
- (2017) Kaori Fukushima et al. EXPERIMENTAL CELL RESEARCH
- Implications for breast cancer treatment from increased autotaxin production in adipose tissue after radiotherapy
- (2017) Guanmin Meng et al. FASEB JOURNAL
- Discovery of 2-[[2-Ethyl-6-[4-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]piperazin-1-yl]-8-methylimidazo[1,2-a]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)thiazole-5-carbonitrile (GLPG1690), a First-in-Class Autotaxin Inhibitor Undergoing Clinical Evaluation for the Treatment of Idiopathic Pulmonary Fibrosis
- (2017) Nicolas Desroy et al. JOURNAL OF MEDICINAL CHEMISTRY
- Novel pleiotropic effects of bioactive phospholipids in human lung cancer metastasis
- (2017) Gabriela Schneider et al. Oncotarget
- Molecular Liver Cancer Prevention in Cirrhosis by Organ Transcriptome Analysis and Lysophosphatidic Acid Pathway Inhibition
- (2016) Shigeki Nakagawa et al. CANCER CELL
- Development of Autotaxin Inhibitors: An Overview of the Patent and Primary Literature
- (2016) Diana Castagna et al. JOURNAL OF MEDICINAL CHEMISTRY
- Autotaxin Regulates Maintenance of Ovarian Cancer Stem Cells through Lysophosphatidic Acid-Mediated Autocrine Mechanism
- (2016) Eun Jin Seo et al. STEM CELLS
- Lysophosphatidic Acid Receptor LPAR6 Supports the Tumorigenicity of Hepatocellular Carcinoma
- (2015) A. Mazzocca et al. CANCER RESEARCH
- Autotaxin is an inflammatory mediator and therapeutic target in thyroid cancer
- (2015) Matthew G K Benesch et al. ENDOCRINE-RELATED CANCER
- Lysophospholipid receptors in drug discovery
- (2015) Yasuyuki Kihara et al. EXPERIMENTAL CELL RESEARCH
- Lysophosphatidate signaling stabilizes Nrf2 and increases the expression of genes involved in drug resistance and oxidative stress responses: implications for cancer treatment
- (2015) Ganesh Venkatraman et al. FASEB JOURNAL
- Tumor-induced inflammation in mammary adipose tissue stimulates a vicious cycle of autotaxin expression and breast cancer progression
- (2015) Matthew G. K. Benesch et al. FASEB JOURNAL
- Regulation of autotaxin expression and secretion by lysophosphatidate and sphingosine 1-phosphate
- (2015) Matthew G. K. Benesch et al. JOURNAL OF LIPID RESEARCH
- Lipid phosphate phosphatases and their roles in mammalian physiology and pathology
- (2015) Xiaoyun Tang et al. JOURNAL OF LIPID RESEARCH
- A Mixed-Crystal Lanthanide Zeolite-like Metal–Organic Framework as a Fluorescent Indicator for Lysophosphatidic Acid, a Cancer Biomarker
- (2015) Shi-Yuan Zhang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Plasma levels of lysophosphatidic acid in ovarian cancer versus controls: a meta-analysis
- (2015) Yi-Yang Li et al. Lipids in Health and Disease
- Lysophosphatidic Acid Signaling in the Nervous System
- (2015) Yun C. Yung et al. NEURON
- Lysophosphatidic acid receptor (LPAR) modulators: The current pharmacological toolbox
- (2015) Sabin Llona-Minguez et al. PROGRESS IN LIPID RESEARCH
- The status of the lysophosphatidic acid receptor type 1 (LPA1R)
- (2015) Inés González-Gil et al. MedChemComm
- Lysophospholipid receptor nomenclature review: IUPHAR Review 8
- (2014) Yasuyuki Kihara et al. BRITISH JOURNAL OF PHARMACOLOGY
- Inhibition of autotaxin delays breast tumor growth and lung metastasis in mice
- (2014) Matthew G. K. Benesch et al. FASEB JOURNAL
- Autotaxin in the crosshairs: Taking aim at cancer and other inflammatory conditions
- (2014) Matthew G.K. Benesch et al. FEBS LETTERS
- Inhibitory effects of lysophosphatidic acid receptor-5 on cellular functions of sarcoma cells
- (2014) Mutsumi Araki et al. GROWTH FACTORS
- The Autotaxin-LPA Axis Emerges as a Novel Regulator of Lymphocyte Homing and Inflammation
- (2014) S. Knowlden et al. JOURNAL OF IMMUNOLOGY
- LPA receptor signaling: pharmacology, physiology, and pathophysiology
- (2014) Yun C. Yung et al. JOURNAL OF LIPID RESEARCH
- Autotaxin: structure-function and signaling
- (2014) Anastassis Perrakis et al. JOURNAL OF LIPID RESEARCH
- PF-8380 and Closely Related Analogs: Synthesis and Structure-Activity Relationship towards Autotaxin Inhibition and Glioma Cell Viability
- (2013) Patrick-Denis St-Cœur et al. ARCHIV DER PHARMAZIE
- Autotaxin-Lysophosphatidic Acid Signaling Axis Mediates Tumorigenesis and Development of Acquired Resistance to Sunitinib in Renal Cell Carcinoma
- (2013) S.-C. Su et al. CLINICAL CANCER RESEARCH
- Lysophosphatidic Acid Stimulates Activation of Focal Adhesion Kinase and Paxillin and Promotes Cell Motility, via LPA1–3, in Human Pancreatic Cancer
- (2013) Yan Liao et al. DIGESTIVE DISEASES AND SCIENCES
- Constitutive Lymphocyte Transmigration across the Basal Lamina of High Endothelial Venules Is Regulated by the Autotaxin/Lysophosphatidic Acid Axis
- (2013) Z. Bai et al. JOURNAL OF IMMUNOLOGY
- A Metabolically-Stabilized Phosphonate Analog of Lysophosphatidic Acid Attenuates Collagen-Induced Arthritis
- (2013) Ioanna Nikitopoulou et al. PLoS One
- Lysophosphatidic Acid Inhibits CD8 T-cell Activation and Control of Tumor Progression
- (2013) S. K. Oda et al. Cancer Immunology Research
- Autotaxin Inhibition with PF-8380 Enhances the Radiosensitivity of Human and Murine Glioblastoma Cell Lines
- (2013) Sandeep R. Bhave et al. Frontiers in Oncology
- Role of the autotaxin–lysophosphatidate axis in cancer resistance to chemotherapy and radiotherapy
- (2012) David N. Brindley et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Lysophospholipids and their receptors in the central nervous system
- (2012) Ji Woong Choi et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Current progress in non-Edg family LPA receptor research
- (2012) Keisuke Yanagida et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Lysophosphatidic acid: Chemical signature of neuropathic pain
- (2012) Hiroshi Ueda et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Sphingosine-1-Phosphate Links Persistent STAT3 Activation, Chronic Intestinal Inflammation, and Development of Colitis-Associated Cancer
- (2012) Jie Liang et al. CANCER CELL
- Orally active lysophosphatidic acid receptor antagonist attenuates pancreatic cancer invasion and metastasis in vivo
- (2012) Mayumi Komachi et al. CANCER SCIENCE
- Unlike Two Peas in a Pod: Lipid Phosphate Phosphatases and Phosphatidate Phosphatases
- (2012) Bernard P. C. Kok et al. CHEMICAL REVIEWS
- Inflammation and ovarian cancer
- (2012) Antonio Macciò et al. CYTOKINE
- LPA5receptor plays a role in pain sensitivity, emotional exploration and reversal learning
- (2012) Z. Callaerts-Vegh et al. GENES BRAIN AND BEHAVIOR
- Targeted Deletion of LPA5Identifies Novel Roles for Lysophosphatidic Acid Signaling in Development of Neuropathic Pain
- (2012) Mu-En Lin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Loss of lysophosphatidic acid receptor-3 enhances cell migration in rat lung tumor cells
- (2011) Mai Hayashi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Regulation of Mammalian Physiology, Development, and Disease by the Sphingosine 1-Phosphate and Lysophosphatidic Acid Receptors
- (2011) Victoria A. Blaho et al. CHEMICAL REVIEWS
- Tumor-secreted lysophostatidic acid accelerates hepatocellular carcinoma progression by promoting differentiation of peritumoral fibroblasts in myofibroblasts
- (2011) Antonio Mazzocca et al. HEPATOLOGY
- Prostate cancer and inflammation: the evidence
- (2011) Karen S Sfanos et al. HISTOPATHOLOGY
- Adipose-specific disruption of autotaxin enhances nutritional fattening and reduces plasma lysophosphatidic acid
- (2011) Rodolphe Dusaulcy et al. JOURNAL OF LIPID RESEARCH
- Possible involvement of lysophosphatidic acid receptor-5 gene in the acquisition of growth advantage of rat tumor cells
- (2011) Kyoko Okabe et al. MOLECULAR CARCINOGENESIS
- Autotaxin and LPA Receptors Represent Potential Molecular Targets for the Radiosensitization of Murine Glioma through Effects on Tumor Vasculature
- (2011) Stephen M. Schleicher et al. PLoS One
- LPA Is a Chemorepellent for B16 Melanoma Cells: Action through the cAMP-Elevating LPA5 Receptor
- (2011) Maikel Jongsma et al. PLoS One
- The absence of LPA receptor 2 reduces the tumorigenesis by ApcMin mutation in the intestine
- (2010) Songbai Lin et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- LPA Receptors: Subtypes and Biological Actions
- (2010) Ji Woong Choi et al. Annual Review of Pharmacology and Toxicology
- Regulation of lysophosphatidate signaling by autotaxin and lipid phosphate phosphatases with respect to tumor progression, angiogenesis, metastasis and chemo-resistance
- (2010) Nasser Samadi et al. BIOCHIMIE
- LPA4 regulates blood and lymphatic vessel formation during mouse embryogenesis
- (2010) H. Sumida et al. BLOOD
- Inhibition of tumor growth and angiogenesis by a lysophosphatidic acid antagonist in an engineered three-dimensional lung cancer xenograft model
- (2010) Xiaoyu Xu et al. CANCER
- Autotaxin Promotes Cancer Invasion via the Lysophosphatidic Acid Receptor 4: Participation of the Cyclic AMP/EPAC/Rac1 Signaling Pathway in Invadopodia Formation
- (2010) Kelly Harper et al. CANCER RESEARCH
- ATX-LPA receptor axis in inflammation and cancer
- (2010) Shuying Liu et al. CELL CYCLE
- Ovarian cancer-derived lysophosphatidic acid stimulates secretion of VEGF and stromal cell-derived factor-1α from human mesenchymal stem cells
- (2010) Eun Su Jeon et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Reactive oxygen species mediate lysophosphatidic acid induced signaling in ovarian cancer cells
- (2010) Jerry A. Saunders et al. FREE RADICAL BIOLOGY AND MEDICINE
- Autotaxin expression and its connection with the TNF-alpha-NF-κB axis in human hepatocellular carcinoma
- (2010) Jian-Min Wu et al. Molecular Cancer
- International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid Receptor Nomenclature
- (2010) J. Chun et al. PHARMACOLOGICAL REVIEWS
- Cancer Cell Expression of Autotaxin Controls Bone Metastasis Formation in Mouse through Lysophosphatidic Acid-Dependent Activation of Osteoclasts
- (2010) Marion David et al. PLoS One
- Accelerated carcinogenesis following liver regeneration is associated with chronic inflammation-induced double-strand DNA breaks
- (2010) H. Barash et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Boronic acid-based inhibitor of autotaxin reveals rapid turnover of LPA in the circulation
- (2010) H. M. H. G. Albers et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- P2Y5 is a Gαi, Gα12/13 G protein-coupled receptor activated by lysophosphatidic acid that reduces intestinal cell adhesion
- (2009) Mike Lee et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Lipid phosphate phosphohydrolase type 1 (LPP1) degrades extracellular lysophosphatidic acidin vivo
- (2009) Jose L. Tomsig et al. BIOCHEMICAL JOURNAL
- Expression of Autotaxin and Lysophosphatidic Acid Receptors Increases Mammary Tumorigenesis, Invasion, and Metastases
- (2009) Shuying Liu et al. CANCER CELL
- Dual Activity Lysophosphatidic Acid Receptor Pan-Antagonist/Autotaxin Inhibitor Reduces Breast Cancer Cell Migration In vitro and Causes Tumor Regression In vivo
- (2009) Honglu Zhang et al. CANCER RESEARCH
- Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability
- (2009) F. Colotta et al. CARCINOGENESIS
- The Absence of LPA2 Attenuates Tumor Formation in an Experimental Model of Colitis-Associated Cancer
- (2009) Songbai Lin et al. GASTROENTEROLOGY
- Identification and Characterization of a Novel Lysophosphatidic Acid Receptor, p2y5/LPA6
- (2009) Keisuke Yanagida et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Unique Ligand Selectivity of the GPR92/LPA5Lysophosphatidate Receptor Indicates Role in Human Platelet Activation
- (2009) Jesica R. Williams et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Thyroid cancer and inflammation
- (2009) Valentina Guarino et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Effects of lysophosphatidic acid on human colon cancer cells and its mechanisms of action
- (2009) Hong Sun et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Two pathways for lysophosphatidic acid production
- (2008) J AOKI BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Age-Dependent Loss of Sperm Production in Mice via Impaired Lysophosphatidic Acid Signaling1
- (2008) Xiaoqin Ye et al. BIOLOGY OF REPRODUCTION
- Expression patterns of the lysophospholipid receptor genes during mouse early development
- (2008) Hideyo Ohuchi et al. DEVELOPMENTAL DYNAMICS
- Lysophosphatidic acid activates telomerase in ovarian cancer cells through hypoxia-inducible factor-1α and the PI3K pathway
- (2008) Kun Yang et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Lysophosphatidic Acid Receptors Determine Tumorigenicity and Aggressiveness of Ovarian Cancer Cells
- (2008) Shuangxing Yu et al. JNCI-Journal of the National Cancer Institute
- Inflammation and Lung Cancer: Roles of Reactive Oxygen/Nitrogen Species
- (2008) Neelam Azad et al. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS
- Role of LPA4/p2y9/GPR23 in Negative Regulation of Cell Motility
- (2008) Zendra Lee et al. MOLECULAR BIOLOGY OF THE CELL
- G protein–coupled receptor P2Y5 and its ligand LPA are involved in maintenance of human hair growth
- (2008) Sandra M Pasternack et al. NATURE GENETICS
- Gene expression profiling for the identification of G-protein coupled receptors in human platelets
- (2007) Stefan Amisten et al. THROMBOSIS RESEARCH
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started