Loss of CMAH during Human Evolution Primed the Monocyte–Macrophage Lineage toward a More Inflammatory and Phagocytic State

Tissue biology perspective on macrophages

(2016) Yasutaka Okabe et al.   NATURE IMMUNOLOGY

Feedback Amplification of Neutrophil Function

(2016) Tamás Németh et al.   TRENDS IN IMMUNOLOGY

Injury, inflammation and the emergence of human-specific genes

(2016) Andrew Baird et al.   WOUND REPAIR AND REGENERATION

GM1 and GD1a gangliosides modulate toxic and inflammatory effects of E. coli lipopolysaccharide by preventing TLR4 translocation into lipid rafts

(2015) Svetlana Nikolaeva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

3.3-million-year-old stone tools from Lomekwi 3, West Turkana, Kenya

(2015) Sonia Harmand et al.   NATURE

Human-specific derived alleles ofCD33and other genes protect against postreproductive cognitive decline

(2015) Flavio Schwarz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New rules may end U.S. chimpanzee research

(2015) D. Grimm   SCIENCE

The role of tissue resident cells in neutrophil recruitment

(2015) Nancy D. Kim et al.   TRENDS IN IMMUNOLOGY

Toll-like receptor 4 ablation in mdx mice reveals innate immunity as a therapeutic target in Duchenne muscular dystrophy

(2015) Christian Giordano et al.   HUMAN MOLECULAR GENETICS

C/EBPα regulates macrophage activation and systemic metabolism

(2014) Bonggi Lee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The contribution of natural selection to present-day susceptibility to chronic inflammatory and autoimmune disease

(2014) Jessica F Brinkworth et al.   CURRENT OPINION IN IMMUNOLOGY

Sepsis: Current Dogma and New Perspectives

(2014) Clifford S. Deutschman et al.   IMMUNITY

Stress, Inflammation, and Defense of Homeostasis

(2014) Raj Chovatiya et al.   MOLECULAR CELL

Blood, Bulbs, and Bunodonts: On Evolutionary Ecology and the Diets of Ardipithecus, Australopithecus, and Early Homo

(2014) Ken Sayers et al.   QUARTERLY REVIEW OF BIOLOGY

Exercise, APOE genotype, and the evolution of the human lifespan

(2014) David A. Raichlen et al.   TRENDS IN NEUROSCIENCES

Broad and direct interaction between TLR and Siglec families of pattern recognition receptors and its regulation by Neu1

(2014) Guo-Yun Chen et al.   eLife

Cellular Mechanisms of Tissue Fibrosis. 4. Structural and functional consequences of skeletal muscle fibrosis

(2013) Richard L. Lieber et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Desialylation of surface receptors as a new dimension in cell signaling

(2013) A. V. Pshezhetsky et al.   BIOCHEMISTRY-MOSCOW

A Special Population of Regulatory T Cells Potentiates Muscle Repair

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N-Glycolylneuraminic acid deficiency worsens cardiac and skeletal muscle pathophysiology in α-sarcoglycan-deficient mice

(2013) Paul T Martin et al.   GLYCOBIOLOGY

Enhanced T Cell Function in a Mouse Model of Human Glycosylation

(2013) G. Buchlis et al.   JOURNAL OF IMMUNOLOGY

Macrophage Plasticity and the Role of Inflammation in Skeletal Muscle Repair

(2013) Yacine Kharraz et al.   MEDIATORS OF INFLAMMATION

Anti-Inflammatory Therapy in Chronic Disease: Challenges and Opportunities

(2013) I. Tabas et al.   SCIENCE

Multifarious roles of sialic acids in immunity

(2012) Ajit Varki et al.   Annals of the New York Academy of Sciences

Regulation of C/EBPβ and resulting functions in cells of the monocytic lineage

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Metabolism of Vertebrate Amino Sugars withN-Glycolyl Groups

(2012) Anne K. Bergfeld et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolism of Vertebrate Amino Sugars withN-Glycolyl Groups

(2012) Leela R. L. Davies et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IL-10 Triggers Changes in Macrophage Phenotype That Promote Muscle Growth and Regeneration

(2012) B. Deng et al.   JOURNAL OF IMMUNOLOGY

Myeloperoxidase: a front-line defender against phagocytosed microorganisms

(2012) S. J. Klebanoff et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Innate immune responses to TLR2 and TLR4 agonists differ between baboons, chimpanzees and humans

(2012) J.F. Brinkworth et al.   JOURNAL OF MEDICAL PRIMATOLOGY

Cell-intrinsic mechanism involving Siglec-5 associated with divergent outcomes of HIV-1 infection in human and chimpanzee CD4 T cells

(2012) Paula C. Soto et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

A non-invasive intratracheal inoculation method for the study of pulmonary melioidosis

(2012) David A. Revelli et al.   Frontiers in Cellular and Infection Microbiology

Toll-like receptors

(2011) Eva Marie Y. Moresco et al.   CURRENT BIOLOGY

Inflammation and wound healing: the role of the macrophage

(2011) Timothy J. Koh et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Where catabolism meets signalling: neuraminidase 1 as a modulator of cell receptors

(2011) Alexey V. Pshezhetsky et al.   GLYCOCONJUGATE JOURNAL

Neu1 Sialidase and Matrix Metalloproteinase-9 Cross-talk Is Essential for Toll-like Receptor Activation and Cellular Signaling

(2011) Samar Abdulkhalek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sexual selection by female immunity against paternal antigens can fix loss of function alleles

(2011) D. Ghaderi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aberrant repair and fibrosis development in skeletal muscle

(2011) Christopher J Mann et al.   Skeletal Muscle

Nonresolving Inflammation

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Relative Over-Reactivity of Human versus Chimpanzee Lymphocytes: Implications for the Human Diseases Associated with Immune Activation

(2010) P. C. Soto et al.   JOURNAL OF IMMUNOLOGY

Evidence for stone-tool-assisted consumption of animal tissues before 3.39 million years ago at Dikika, Ethiopia

(2010) Shannon P. McPherron et al.   NATURE

A Human-Specific Deletion in Mouse Cmah Increases Disease Severity in the mdx Model of Duchenne Muscular Dystrophy

(2010) K. Chandrasekharan et al.   Science Translational Medicine

Functional Comparison of Innate Immune Signaling Pathways in Primates

(2010) Luis B. Barreiro et al.   PLoS Genetics

Alternative activation of macrophages by IL-4 impairs phagocytosis of pathogens but potentiates microbial-induced signalling and cytokine secretion

(2009) A. Varin et al.   BLOOD

Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses

(2009) T. H. Mogensen   CLINICAL MICROBIOLOGY REVIEWS

Resilience to Bacterial Infection: Difference between Species Could Be Due to Proteins in Serum

(2009) H. Shaw Warren et al.   JOURNAL OF INFECTIOUS DISEASES

A CREB-C/EBP  cascade induces M2 macrophage-specific gene expression and promotes muscle injury repair

(2009) D. Ruffell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

LPS/TLR4 signal transduction pathway

(2008) Yong-Chen Lu et al.   CYTOKINE

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE

Wound repair and regeneration

(2008) Geoffrey C. Gurtner et al.   NATURE

Evidence for a human-specific mechanism for diet and antibody-mediated inflammation in carcinoma progression

(2008) M. Hedlund et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA