CD27-Mediated Regulatory T Cell Depletion and Effector T Cell Costimulation Both Contribute to Antitumor Efficacy
出版年份 2017 全文链接
标题
CD27-Mediated Regulatory T Cell Depletion and Effector T Cell Costimulation Both Contribute to Antitumor Efficacy
作者
关键词
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出版物
JOURNAL OF IMMUNOLOGY
Volume 199, Issue 12, Pages 4110-4123
出版商
The American Association of Immunologists
发表日期
2017-11-07
DOI
10.4049/jimmunol.1700606
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Safety and Activity of Varlilumab, a Novel and First-in-Class Agonist Anti-CD27 Antibody, in Patients With Advanced Solid Tumors
- (2017) Howard A. Burris et al. JOURNAL OF CLINICAL ONCOLOGY
- CD27 Agonism Plus PD-1 Blockade Recapitulates CD4+ T-cell Help in Therapeutic Anticancer Vaccination
- (2016) T. Ahrends et al. CANCER RESEARCH
- Inherited CD70 deficiency in humans reveals a critical role for the CD70–CD27 pathway in immunity to Epstein-Barr virus infection
- (2016) Kazushi Izawa et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Combined immunodeficiency and Epstein-Barr virus–induced B cell malignancy in humans with inherited CD70 deficiency
- (2016) Hassan Abolhassani et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Novel mutations in TNFRSF7/CD27: Clinical, immunologic, and genetic characterization of human CD27 deficiency
- (2015) Omar K. Alkhairy et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Combination cancer immunotherapy and new immunomodulatory targets
- (2015) Kathleen M. Mahoney et al. NATURE REVIEWS DRUG DISCOVERY
- PD-1 Blockade with Nivolumab in Relapsed or Refractory Hodgkin's Lymphoma
- (2015) Stephen M. Ansell et al. NEW ENGLAND JOURNAL OF MEDICINE
- OX40 engagement depletes intratumoral Tregs via activating FcγRs, leading to antitumor efficacy
- (2014) Yannick Bulliard et al. IMMUNOLOGY AND CELL BIOLOGY
- Dual Function of CD70 in Viral Infection: Modulator of Early Cytokine Responses and Activator of Adaptive Responses
- (2014) Atef Allam et al. JOURNAL OF IMMUNOLOGY
- Agonistic CD40 Antibodies and Cancer Therapy
- (2013) R. H. Vonderheide et al. CLINICAL CANCER RESEARCH
- Activating Fc γ receptors contribute to the antitumor activities of immunoregulatory receptor-targeting antibodies
- (2013) Yannick Bulliard et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti–CTLA-4 therapy against melanoma
- (2013) Tyler R. Simpson et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+regulatory T cell development via the CD27–CD70 pathway
- (2013) Jonathan M. Coquet et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Agonist Anti-Human CD27 Monoclonal Antibody Induces T Cell Activation and Tumor Immunity in Human CD27-Transgenic Mice
- (2013) L.-Z. He et al. JOURNAL OF IMMUNOLOGY
- CD27-CD70 Costimulation Controls T Cell Immunity during Acute and Persistent Cytomegalovirus Infection
- (2013) S. P. M. Welten et al. JOURNAL OF VIROLOGY
- Nivolumab plus Ipilimumab in Advanced Melanoma
- (2013) Jedd D. Wolchok et al. NEW ENGLAND JOURNAL OF MEDICINE
- CD27 Signaling Increases the Frequency of Regulatory T Cells and Promotes Tumor Growth
- (2012) C. Claus et al. CANCER RESEARCH
- Development of a Human Monoclonal Antibody for Potential Therapy of CD27-Expressing Lymphoma and Leukemia
- (2012) L. A. Vitale et al. CLINICAL CANCER RESEARCH
- Combined immunodeficiency with life-threatening EBV-associated lymphoproliferative disorder in patients lacking functional CD27
- (2012) E. Salzer et al. HAEMATOLOGICA
- CD70-Driven Costimulation Induces Survival or Fas-Mediated Apoptosis of T Cells Depending on Antigenic Load
- (2012) F. M. Wensveen et al. JOURNAL OF IMMUNOLOGY
- CD27 Stimulation Promotes the Frequency of IL-7 Receptor-Expressing Memory Precursors and Prevents IL-12-Mediated Loss of CD8+ T Cell Memory in the Absence of CD4+ T Cell Help
- (2012) H. Dong et al. JOURNAL OF IMMUNOLOGY
- Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer
- (2012) Julie R. Brahmer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer
- (2012) Suzanne L. Topalian et al. NEW ENGLAND JOURNAL OF MEDICINE
- CD27 deficiency is associated with combined immunodeficiency and persistent symptomatic EBV viremia
- (2011) Joris M. van Montfrans et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Interaction with Fc RIIB Is Critical for the Agonistic Activity of Anti-CD40 Monoclonal Antibody
- (2011) A. L. White et al. JOURNAL OF IMMUNOLOGY
- CD70 Is Selectively Expressed on Th1 but Not on Th2 Cells and Is Required for Th1-Type Immune Responses
- (2011) Tatsuyoshi Kawamura et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Opposing Effects of CD70 Costimulation during Acute and Chronic Lymphocytic Choriomeningitis Virus Infection of Mice
- (2011) P. Penaloza-MacMaster et al. JOURNAL OF VIROLOGY
- Inhibitory Fc Receptor Engagement Drives Adjuvant and Anti-Tumor Activities of Agonistic CD40 Antibodies
- (2011) F. Li et al. SCIENCE
- Anti-tumor effects of depleting and non-depleting anti-CD27 monoclonal antibodies in immune-competent mice
- (2010) Tamami Sakanishi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Continuous CD27 triggeringin vivostrongly reduces NK cell numbers
- (2010) Veerle De Colvenaer et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Control of Established Melanoma by CD27 Stimulation Is Associated With Enhanced Effector Function and Persistence, and Reduced PD-1 Expression of Tumor Infiltrating CD8+ T Cells
- (2010) Drew J. Roberts et al. JOURNAL OF IMMUNOTHERAPY
- Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
- (2010) F. Stephen Hodi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Costimulatory ligand CD70 allows induction of CD8+ T-cell immunity by immature dendritic cells in a vaccination setting
- (2009) A. M. Keller et al. BLOOD
- Protective CD8 T Cell Memory Is Impaired during Chronic CD70-Driven Costimulation
- (2009) K. P. J. M. van Gisbergen et al. JOURNAL OF IMMUNOLOGY
- Soluble CD70: a novel immunotherapeutic agent for experimental glioblastoma
- (2009) James Miller et al. JOURNAL OF NEUROSURGERY
- Enhanced formation and survival of CD4+CD25hiFoxp3+T-cells in chronic lymphocytic leukemia
- (2009) Margot Jak et al. LEUKEMIA & LYMPHOMA
- Expression of Costimulatory Ligand CD70 on Steady-State Dendritic Cells Breaks CD8+ T Cell Tolerance and Permits Effective Immunity
- (2008) Anna M. Keller et al. IMMUNITY
- OX40 triggering blocks suppression by regulatory T cells and facilitates tumor rejection
- (2008) Silvia Piconese et al. JOURNAL OF EXPERIMENTAL MEDICINE
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