Protein kinase STK25 aggravates the severity of non-alcoholic fatty pancreas disease in mice

Insulitis in human diabetes: a histological evaluation of donor pancreases

(2016) Marcus Lundberg et al.   DIABETOLOGIA

Overexpression of protein kinase STK25 in mice exacerbates ectopic lipid accumulation, mitochondrial dysfunction and insulin resistance in skeletal muscle

(2016) Urszula Chursa et al.   DIABETOLOGIA

STK25 is a critical determinant in nonalcoholic steatohepatitis

(2016) Manoj Amrutkar et al.   FASEB JOURNAL

The correlation between pancreatic steatosis and metabolic syndrome in a Chinese population

(2016) Jie Zhou et al.   PANCREATOLOGY

Exploring the metabolic syndrome: Nonalcoholic fatty pancreas disease

(2016) Roberto Catanzaro et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Prevalence of Non-Alcoholic Fatty Pancreas Disease (NAFPD) and its risk factors among adult medical check-up patients in a private hospital: a large cross sectional study

(2015) Cosmas Rinaldi A. Lesmana et al.   BMC GASTROENTEROLOGY

Genetic Disruption of Protein Kinase STK25 Ameliorates Metabolic Defects in a Diet-Induced Type 2 Diabetes Model

(2015) Manoj Amrutkar et al.   DIABETES

Protein kinase STK25 controls lipid partitioning in hepatocytes and correlates with liver fat content in humans

(2015) Manoj Amrutkar et al.   DIABETOLOGIA

Protein kinase STK25 regulates hepatic lipid partitioning and progression of liver steatosis and NASH

(2015) Manoj Amrutkar et al.   FASEB JOURNAL

MST kinases in development and disease

(2015) Barry J. Thompson et al.   JOURNAL OF CELL BIOLOGY

Cancer-Stellate Cell Interactions Perpetuate the Hypoxia-Fibrosis Cycle in Pancreatic Ductal Adenocarcinoma

(2015) Mert Erkan et al.   NEOPLASIA

Vitamin A Deficiency Causes Hyperglycemia and Loss of Pancreatic β-Cell Mass

(2014) Steven E. Trasino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MST1 is a key regulator of beta cell apoptosis and dysfunction in diabetes

(2014) Amin Ardestani et al.   NATURE MEDICINE

Enigmatic Ectopic Fat: Prevalence of Nonalcoholic Fatty Pancreas Disease and Its Associated Factors in a Chinese Population

(2014) Chih‐Yuan Wang et al.   Journal of the American Heart Association

Exchange protein activated by cAMP 1 (Epac1)-deficient mice develop β-cell dysfunction and metabolic syndrome

(2013) Alan K. L. Kai et al.   FASEB JOURNAL

Increased expression of STK25 leads to impaired glucose utilization and insulin sensitivity in mice challenged with a high-fat diet

(2013) Emmelie Cansby et al.   FASEB JOURNAL

The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearance

(2013) Motoyuki Tamaki et al.   JOURNAL OF CLINICAL INVESTIGATION

Deficiency for endoglin in tumor vasculature weakens the endothelial barrier to metastatic dissemination

(2013) Charlotte Anderberg et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes

(2013) Tony Jourdan et al.   NATURE MEDICINE

Diabetes Mellitus and the β Cell: The Last Ten Years

(2012) Frances M. Ashcroft et al.   CELL

Serine/threonine protein kinase 25 (STK25): a novel negative regulator of lipid and glucose metabolism in rodent and human skeletal muscle

(2012) A. Nerstedt et al.   DIABETOLOGIA

Cellular Inhibitor of Apoptosis Protein-1 (cIAP1) Plays a Critical Role in β-Cell Survival under Endoplasmic Reticulum Stress

(2012) Yanfei Qi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Elevated TCA cycle function in the pathology of diet-induced hepatic insulin resistance and fatty liver

(2012) Santhosh Satapati et al.   JOURNAL OF LIPID RESEARCH

Leptin revisited: its mechanism of action and potential for treating diabetes

(2012) Roberto Coppari et al.   NATURE REVIEWS DRUG DISCOVERY

Excessive Hepatic Mitochondrial TCA Cycle and Gluconeogenesis in Humans with Nonalcoholic Fatty Liver Disease

(2011) Nishanth E. Sunny et al.   Cell Metabolism

 40 Isoform of p53 Controls  -Cell Proliferation and Glucose Homeostasis in Mice

(2011) C. Hinault et al.   DIABETES

The clinical significance of pancreatic steatosis

(2011) Mark M. Smits et al.   Nature Reviews Gastroenterology & Hepatology

Bcl-2 proteins in diabetes: mitochondrial pathways of β-cell death and dysfunction

(2011) Esteban N. Gurzov et al.   TRENDS IN CELL BIOLOGY

β-Cell failure in type 2 diabetes

(2011) Gil Leibowitz et al.   Journal of Diabetes Investigation

Glucolipotoxicity in Pancreatic β-Cells

(2011) Ji-Won Kim et al.   Diabetes & Metabolism Journal

 -Cell Growth and Regeneration: Replication Is Only Part of the Story

(2010) S. Bonner-Weir et al.   DIABETES

Glucolipotoxicity of the pancreatic beta cell

(2009) Vincent Poitout et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Molecular and Metabolic Evidence for Mitochondrial Defects Associated With  -Cell Dysfunction in a Mouse Model of Type 2 Diabetes

(2009) H. Lu et al.   DIABETES

Human genetics illuminates the paths to metabolic disease

(2009) Stephen O’Rahilly   NATURE

Hypoxia stimulates pancreatic stellate cells to induce fibrosis and angiogenesis in pancreatic cancer

(2008) Atsushi Masamune et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Inhibition of Foxo1 Protects Pancreatic Islet  -Cells Against Fatty Acid and Endoplasmic Reticulum Stress-Induced Apoptosis

(2008) S. C. Martinez et al.   DIABETES

Insulitis in type 2 diabetes

(2008) M. Böni-Schnetzler et al.   DIABETES OBESITY & METABOLISM

MKK3 signalling plays an essential role in leukocyte-mediated pancreatic injury in the multiple low-dose streptozotocin model

(2008) Kyoichi Fukuda et al.   LABORATORY INVESTIGATION