Neuroprotective and regenerative roles of intranasal Wnt-3a administration after focal ischemic stroke in mice

Wnt3a, a Protein Secreted by Mesenchymal Stem Cells Is Neuroprotective and Promotes Neurocognitive Recovery Following Traumatic Brain Injury

(2016) Yuhai Zhao et al.   STEM CELLS

Intranasal Delivery of Apelin-13 Is Neuroprotective and Promotes Angiogenesis After Ischemic Stroke in Mice

(2015) Dongdong Chen et al.   ASN Neuro

Intranasal Delivery of Bone Marrow Mesenchymal Stem Cells Improved Neurovascular Regeneration and Rescued Neuropsychiatric Deficits after Neonatal Stroke in Rats

(2015) Zheng Zachory Wei et al.   CELL TRANSPLANTATION

Intranasal delivery of hypoxia-preconditioned bone marrow-derived mesenchymal stem cells enhanced regenerative effects after intracerebral hemorrhagic stroke in mice

(2015) Jinmei Sun et al.   EXPERIMENTAL NEUROLOGY

Upregulation of the expression of Wnt5a promotes the proliferation of pancreatic cancer cells in vitro and in a nude mouse model

(2015) HAIJI BO et al.   Molecular Medicine Reports

Neuroprotection for ischaemic stroke: Current status and challenges

(2015) Antonio Moretti et al.   PHARMACOLOGY & THERAPEUTICS

Wnt/β-catenin coupled with HIF-1α/VEGF signaling pathways involved in galangin neurovascular unit protection from focal cerebral ischemia

(2015) Chuanhong Wu et al.   Scientific Reports

Update in the Management of Acute Ischemic Stroke

(2014) Nelson J. Maldonado et al.   CRITICAL CARE CLINICS

Biosafety Challenges for Use of Lentiviral Vectors in Gene Therapy

(2014) Michael Rothe et al.   CURRENT GENE THERAPY

Promoting neurogenesis via Wnt/β-catenin signaling pathway accounts for the neurorestorative effects of morroniside against cerebral ischemia injury

(2014) Fang-Ling Sun et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Neurorestorative Therapy for Stroke

(2014) Jieli Chen et al.   Frontiers in Human Neuroscience

PTEN degradation after ischemic stroke: A double-edged sword

(2014) W. Li et al.   NEUROSCIENCE

Mobilization of Endogenous Bone Marrow Derived Endothelial Progenitor Cells and Therapeutic Potential of Parathyroid Hormone after Ischemic Stroke in Mice

(2014) Li-Li Wang et al.   PLoS One

HES5 Is a Key Mediator of Wnt-3a-Induced Neuronal Differentiation

(2014) Carolin Mußmann et al.   STEM CELLS AND DEVELOPMENT

The Wnt Receptor Ryk Reduces Neuronal and Cell Survival Capacity by Repressing FOXO Activity During the Early Phases of Mutant Huntingtin Pathogenicity

(2014) Cendrine Tourette et al.   PLOS BIOLOGY

Importance of Preclinical Research in the Development of Neuroprotective Strategies for Ischemic Stroke

(2014) Ain A. Neuhaus et al.   JAMA Neurology

Delayed Intranasal Delivery of Hypoxic-Preconditioned Bone Marrow Mesenchymal Stem Cells Enhanced Cell Homing and Therapeutic Benefits after Ischemic Stroke in Mice

(2013) Ning Wei et al.   CELL TRANSPLANTATION

Up-regulation of the canonical Wnt-3A and Sonic hedgehog signaling underlies melanocortin-induced neurogenesis after cerebral ischemia

(2013) Luca Spaccapelo et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

BDNF-based synaptic repair as a disease-modifying strategy for neurodegenerative diseases

(2013) Bai Lu et al.   NATURE REVIEWS NEUROSCIENCE

Preconditioning Strategy in Stem Cell Transplantation Therapy

(2013) Shan Ping Yu et al.   Translational Stroke Research

Pharmacological Inhibition of the Wnt Acyltransferase PORCN Prevents Growth of WNT-Driven Mammary Cancer

(2012) K. D. Proffitt et al.   CANCER RESEARCH

A novel stroke therapy of pharmacologically induced hypothermia after focal cerebral ischemia in mice

(2012) Ko-Eun Choi et al.   FASEB JOURNAL

Atorvastatin and whisker stimulation synergistically enhance angiogenesis in the barrel cortex of rats following focal ischemia

(2012) Yunyun Zhang et al.   NEUROSCIENCE LETTERS

Krüppel-Like Factor 8 Is a New Wnt/Beta-Catenin Signaling Target Gene and Regulator in Hepatocellular Carcinoma

(2012) Tian Yang et al.   PLoS One

Wnt Signaling Enhances Neurogenesis and Improves Neurological Function after Focal Ischemic Injury

(2012) Adi Shruster et al.   PLoS One

Glycogen Synthase Kinase-3 Inhibition Promotes Proliferation and Neuronal Differentiation of Human-Induced Pluripotent Stem Cell-Derived Neural Progenitors

(2012) Fereshteh Esfandiari et al.   STEM CELLS AND DEVELOPMENT

A Small Molecule that Promotes Cardiac Differentiation of Human Pluripotent Stem Cells under Defined, Cytokine- and Xeno-free Conditions

(2012) Itsunari Minami et al.   Cell Reports

Treatment of cerebral ischemia with melanocortins acting at MC4 receptors induces marked neurogenesis and long-lasting functional recovery

(2011) Daniela Giuliani et al.   ACTA NEUROPATHOLOGICA

Intranasal delivery of biologics to the central nervous system

(2011) Jeffrey J. Lochhead et al.   ADVANCED DRUG DELIVERY REVIEWS

Canonical Wnt signaling promotes the proliferation and neurogenesis of peripheral olfactory stem cells during postnatal development and adult regeneration

(2011) Y.-Z. Wang et al.   JOURNAL OF CELL SCIENCE

Wnt Signaling Regulates Neuronal Differentiation of Cortical Intermediate Progenitors

(2011) R. N. Munji et al.   JOURNAL OF NEUROSCIENCE

Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination

(2011) Stephen P J Fancy et al.   NATURE NEUROSCIENCE

Inhibition of prolyl hydroxylases by dimethyloxaloylglycine after stroke reduces ischemic brain injury and requires hypoxia inducible factor-1α

(2011) Molly E. Ogle et al.   NEUROBIOLOGY OF DISEASE

Expression of brain-derived neurotrophic factor is regulated by the Wnt signaling pathway

(2011) Hyun Yi et al.   NEUROREPORT

Effects of environmental enrichment and voluntary exercise on neurogenesis, learning and memory, and pattern separation: BDNF as a critical variable?

(2011) Pedro Bekinschtein et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Wnt3a Promotes Hippocampal Neurogenesis by Shortening Cell Cycle Duration of Neural Progenitor Cells

(2010) Yutaka Yoshinaga et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

The Role of Wnt Signaling in Physiological and Pathological Angiogenesis

(2010) Elisabetta Dejana   CIRCULATION RESEARCH

Wnt-3a and Wnt-3 differently stimulate proliferation and neurogenesis of spinal neural precursors and promote neurite outgrowth by canonical signaling

(2010) Monica D. David et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Wnt Isoform-Specific Interactions with Coreceptor Specify Inhibition or Potentiation of Signaling by LRP6 Antibodies

(2010) Yan Gong et al.   PLoS One

Wnt Signaling Regulates Symmetry of Division of Neural Stem Cells in the Adult Brain and in Response to Injury

(2010) David Piccin et al.   STEM CELLS

Gene Targeting of a Disease-Related Gene in Human Induced Pluripotent Stem and Embryonic Stem Cells

(2009) Jizhong Zou et al.   Cell Stem Cell

Pten Deletion in Adult Neural Stem/Progenitor Cells Enhances Constitutive Neurogenesis

(2009) C. Gregorian et al.   JOURNAL OF NEUROSCIENCE

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

(2009) Shih-Min A. Huang et al.   NATURE

Enhanced neurogenesis and cell migration following focal ischemia and peripheral stimulation in mice

(2008) Wen-Lei Li et al.   Developmental Neurobiology

In vitro hypoxic preconditioning of embryonic stem cells as a strategy of promoting cell survival and functional benefits after transplantation into the ischemic rat brain

(2008) Michelle Hedrick Theus et al.   EXPERIMENTAL NEUROLOGY

Induction of the Wnt Antagonist, Dickkopf-1, Contributes to the Development of Neuronal Death in Models of Brain Focal Ischemia

(2008) Federica Mastroiacovo et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Ischemic stroke and neurogenesis in the subventricular zone

(2008) Rui Lan Zhang et al.   NEUROPHARMACOLOGY

Wnt-mediated self-renewal of neural stem/progenitor cells

(2008) M. Y. S. Kalani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wnt signaling in neuroprotection and stem cell differentiation

(2008) Enrique M. Toledo et al.   PROGRESS IN NEUROBIOLOGY