Unexpected DNA binding properties with correlated downstream biological applications in mono vs. bis-1,8-naphthalimide Ru(ii)-polypyridyl conjugates

Detailed Biological Profiling of a Photoactivated and Apoptosis Inducing pdppz Ruthenium(II) Polypyridyl Complex in Cancer Cells

(2015) Suzanne M. Cloonan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Redesigning the DNA-Targeted Chromophore in Platinum-Acridine Anticancer Agents: A Structure-Activity Relationship Study

(2014) Amanda J. Pickard et al.   CHEMISTRY-A EUROPEAN JOURNAL

Ruthenium(II) polypyridyl complexes: Cellular uptake, cell image and apoptosis of HeLa cancer cells induced by double targets

(2014) Qianqian Yu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design and Biological Evaluation of New Platinum(II) Complexes Bearing Ligands with DNA-Targeting Ability

(2014) Jacqueline M. Herrera et al.   INORGANIC CHEMISTRY

Fluorescent Rhenium-Naphthalimide Conjugates as Cellular Imaging Agents

(2014) Emily E. Langdon-Jones et al.   INORGANIC CHEMISTRY

Supramolecular Approach to Enantioselective DNA Recognition Using Enantiomerically Resolved Cationic 4-Amino-1,8-naphthalimide-Based Tröger’s Bases

(2014) Swagata Banerjee et al.   JOURNAL OF ORGANIC CHEMISTRY

In Vivo and in Situ Tracking Cancer Chemotherapy by Highly Photostable NIR Fluorescent Theranostic Prodrug

(2014) Xumeng Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Detection and Cellular Imaging of Human Cancer Enzyme Using a Turn-On, Wavelength-Shiftable, Self-Immolative Profluorophore

(2014) Suraj U. Hettiarachchi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Toward a Chemical Marker for Inflammatory Disease: A Fluorescent Probe for Membrane-Localized Thioredoxin

(2014) Min Hee Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis, photophysical and cytotoxicity evaluations of DNA targeting agents based on 3-amino-1,8-naphthalimide derived Tröger's bases

(2014) Samantha Murphy et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Biologically targeted probes for Zn2+: a diversity oriented modular “click-SNAr-click” approach

(2014) J. Pancholi et al.   Chemical Science

A water-soluble boronate-based fluorescent probe for the selective detection of peroxynitrite and imaging in living cells

(2014) Xiaolong Sun et al.   Chemical Science

Using Fluorescent Post-Labeling To Probe the Subcellular Localization of DNA-Targeted Platinum Anticancer Agents

(2013) Song Ding et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis, spectroscopic and biological studies of a fluorescent Pt(ii) (terpy) based 1,8-naphthalimide conjugate as a DNA targeting agent

(2013) Swagata Banerjee et al.   CHEMICAL COMMUNICATIONS

Recent advances in the development of 1,8-naphthalimide based DNA targeting binders, anticancer and fluorescent cellular imaging agents

(2013) Swagata Banerjee et al.   CHEMICAL SOCIETY REVIEWS

Highly Selective Off–On Fluorescent Probe for Imaging Thioredoxin Reductase in Living Cells

(2013) Liangwei Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The effect of the 4-amino functionality on the photophysical and DNA binding properties of alkyl-pyridinium derived 1,8-naphthalimides

(2013) Swagata Banerjee et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Targeting the endoplasmic reticulum with a membrane-interactive luminescent ruthenium(ii) polypyridyl complex

(2013) Martin R. Gill et al.   Chemical Science

Naphthalimide trifluoroacetyl acetonate: a hydrazine-selective chemodosimetric sensor

(2013) Min Hee Lee et al.   Chemical Science

Photophysical and biological investigation of novel luminescent Ru(ii)-polypyridyl-1,8-naphthalimide Tröger's bases as cellular imaging agents

(2012) Robert B. P. Elmes et al.   CHEMICAL COMMUNICATIONS

Ruthenium(ii) polypyridyl complexes and DNA—from structural probes to cellular imaging and therapeutics

(2012) Martin R. Gill et al.   CHEMICAL SOCIETY REVIEWS

Ruthenium Complexes with Hydrophobic Ligands That Are Key Factors for the Optical Imaging of Physiological Hypoxia

(2012) Hirokazu Komatsu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Into the minor groove

(2012) Stephen Neidle   Nature Chemistry

Crystal structures of Λ-[Ru(phen)2dppz]2+ with oligonucleotides containing TA/TA and AT/AT steps show two intercalation modes

(2012) Hakan Niyazi et al.   Nature Chemistry

Crystal structure of Δ-[Ru(bpy)2dppz]2+ bound to mismatched DNA reveals side-by-side metalloinsertion and intercalation

(2012) Hang Song et al.   Nature Chemistry

Synthesis and photophysical evaluation of a pyridinium 4-amino-1,8-naphthalimide derivative that upon intercalation displays preference for AT-rich double-stranded DNA

(2012) Swagata Banerjee et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Naphthalimide-Tagged Ruthenium–Arene Anticancer Complexes: Combining Coordination with Intercalation

(2012) Kelly J. Kilpin et al.   ORGANOMETALLICS

Synthesis and photophysical evaluations of fluorescent quaternary bipyridyl-1,8-naphthalimide conjugates as nucleic acid targeting agents

(2012) Gary J. Ryan et al.   SUPRAMOLECULAR CHEMISTRY

Live Cell Luminescence Imaging As a Function of Delivery Mechanism

(2011) Xiaohe Tian et al.   CHEMBIOCHEM

Ruthenium(II) Metallo-intercalators: DNA Imaging and Cytotoxicity

(2011) Martin R. Gill et al.   CHEMBIOCHEM

Phosphorescent heavy-metal complexes for bioimaging

(2011) Qiang Zhao et al.   CHEMICAL SOCIETY REVIEWS

Photoactive RuII-Polypyridyl Complexes that Display Sequence Selectivity and High-Affinity Binding to Duplex DNA through Groove Binding

(2011) Amrita Ghosh et al.   CHEMISTRY-A EUROPEAN JOURNAL

Environmental effects on the photophysics of transition metal complexes with dipyrido[2,3-a:3′,2′-c]phenazine (dppz) and related ligands

(2011) Andrew W. McKinley et al.   COORDINATION CHEMISTRY REVIEWS

Synthesis, structures, cellular uptake and apoptosis-inducing properties of highly cytotoxic ruthenium-Norharman complexes

(2011) Caiping Tan et al.   DALTON TRANSACTIONS

Correlation Between Cellular Localization and Binding Preference to RNA, DNA, and Phospholipid Membrane for Luminescent Ruthenium(II) Complexes

(2011) Maria Matson et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Luminescent Ruthenium(II) Polypyridyl Functionalized Gold Nanoparticles; Their DNA Binding Abilities and Application As Cellular Imaging Agents

(2011) Robert B. P. Elmes et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure determination of an intercalating ruthenium dipyridophenazine complex which kinks DNA by semiintercalation of a tetraazaphenanthrene ligand

(2011) J. P. Hall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipophilic ruthenium complexes with tuned cell membrane affinity and photoactivated uptake

(2010) Frida R. Svensson et al.   BIOPHYSICAL CHEMISTRY

Efficient DNA photocleavage by [Ru(bpy)2(dppn)]2+ with visible light

(2010) Yujie Sun et al.   CHEMICAL COMMUNICATIONS

Substituted dipyridophenazine complexes of Cr(iii): Synthesis, enantiomeric resolution and binding interactions with calf thymus DNA

(2010) Suni Vasudevan et al.   DALTON TRANSACTIONS

Synthesis, Photophysical, and DNA Binding Studies of Fluorescent Tröger’s Base Derived 4-Amino-1,8-naphthalimide Supramolecular Clefts

(2010) Emma B. Veale et al.   JOURNAL OF ORGANIC CHEMISTRY

Differentiating quadruplexes: binding preferences of a luminescent dinuclear ruthenium(ii) complex with four-stranded DNA structures

(2010) Tom Wilson et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Multimodal cell imaging by ruthenium polypyridyl labelled cell penetrating peptides

(2009) Lynda Cosgrave et al.   CHEMICAL COMMUNICATIONS

Nuclear targets of photodynamic tridentate ruthenium complexes

(2009) Ran Zhao et al.   DALTON TRANSACTIONS

Mixed f−d Coordination Complexes as Dual Visible- and Near-Infrared-Emitting Probes for Targeting DNA

(2009) Aline M. Nonat et al.   INORGANIC CHEMISTRY

A ruthenium(II) polypyridyl complex for direct imaging of DNA structure in living cells

(2009) Martin R. Gill et al.   Nature Chemistry

4-Amino-1,8-naphthalimide-Based Tröger’s Bases As High Affinity DNA Targeting Fluorescent Supramolecular Scaffolds

(2009) Emma B. Veale et al.   ORGANIC LETTERS

Structural organization of a {ruthenium[tris(bipyridyl)]}2+ complex by strong π–π stacking of a tethered 1,8-naphthalimide synthon: Impact on electrochemical and spectral properties

(2009) Daniel L. Reger et al.   POLYHEDRON

Mechanism of Cellular Uptake of a Ruthenium Polypyridyl Complex†

(2008) Cindy A. Puckett et al.   BIOCHEMISTRY

Naphthalimide intercalators with chiral amino side chains: Effects of chirality on DNA binding, photodamage and antitumor cytotoxicity

(2008) Qing Yang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

New trends for metal complexes with anticancer activity

(2008) Pieter CA Bruijnincx et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Luminescent Dipyridophenazine-Ruthenium Probes for Liposome Membranes

(2008) Frida R. Svensson et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Highly Effective DNA Photocleavage by Novel “Rigid” Ru(bpy)3-4-nitro- and -4-amino-1,8-naphthalimide Conjugates

(2007) Gary J. Ryan et al.   INORGANIC CHEMISTRY

Luminescent Biological Probes Derived from Ruthenium(II) Estradiol Polypyridine Complexes

(2007) Kenneth Kam-Wing Lo et al.   INORGANIC CHEMISTRY