The Intersection of NGF/TrkA Signaling and Amyloid Precursor Protein Processing in Alzheimer’s Disease Neuropathology
出版年份 2017 全文链接
标题
The Intersection of NGF/TrkA Signaling and Amyloid Precursor Protein Processing in Alzheimer’s Disease Neuropathology
作者
关键词
-
出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 18, Issue 6, Pages 1319
出版商
MDPI AG
发表日期
2017-06-20
DOI
10.3390/ijms18061319
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Cerebrospinal Fluid Levels of a 20–22 kDa NH2 Fragment of Human Tau Provide a Novel Neuronal Injury Biomarker in Alzheimer's Disease and Other Dementias
- (2018) Giuseppina Amadoro et al. JOURNAL OF ALZHEIMERS DISEASE
- ProNGF, but Not NGF, Switches from Neurotrophic to Apoptotic Activity in Response to Reductions in TrkA Receptor Levels
- (2017) Maria Ioannou et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Impaired NGF/TrkA Signaling Causes Early AD-Linked Presynaptic Dysfunction in Cholinergic Primary Neurons
- (2017) Valentina Latina et al. Frontiers in Cellular Neuroscience
- Association of TrkA and APP Is Promoted by NGF and Reduced by Cell Death-Promoting Agents
- (2017) Nadia Canu et al. Frontiers in Molecular Neuroscience
- Truncation of Tau Protein and its Pathological Significance in Alzheimer's Disease
- (2017) Francisco García-Sierra et al. JOURNAL OF ALZHEIMERS DISEASE
- Activation of the Amyloidogenic Route by NGF Deprivation Induces Apoptotic Death in PC12 Cells
- (2017) Carmela Matrone et al. JOURNAL OF ALZHEIMERS DISEASE
- A NH2 Tau Fragment Targets Neuronal Mitochondria at AD Synapses: Possible Implications for Neurodegeneration
- (2017) Giuseppina Amadoro et al. JOURNAL OF ALZHEIMERS DISEASE
- NGF controls APP cleavage by downregulating APP phosphorylation at Thr668: relevance for Alzheimer's disease
- (2016) Viviana Triaca et al. AGING CELL
- Alzheimer's disease: The amyloid hypothesis on trial
- (2016) Judith R. Harrison et al. BRITISH JOURNAL OF PSYCHIATRY
- Amyloid precursor protein–mediated endocytic pathway disruption induces axonal dysfunction and neurodegeneration
- (2016) Wei Xu et al. JOURNAL OF CLINICAL INVESTIGATION
- Suspected non-Alzheimer disease pathophysiology — concept and controversy
- (2016) Clifford R. Jack et al. Nature Reviews Neurology
- Impairment of the nerve growth factor pathway driving amyloid accumulation in cholinergic neurons: the incipit of the Alzheimer′s disease story?
- (2016) Viviana Triaca et al. Neural Regeneration Research
- Neuronal amyloid-β accumulation within cholinergic basal forebrain in ageing and Alzheimer’s disease
- (2015) Alaina Baker-Nigh et al. BRAIN
- The NGF Metabolic Pathway in the CNS and its Dysregulation in Down Syndrome and Alzheimer's Disease
- (2015) M. Florencia Iulita et al. Current Alzheimer Research
- Pre-synaptic C-terminal truncated tau is released from cortical synapses in Alzheimer's disease
- (2015) Sophie Sokolow et al. JOURNAL OF NEUROCHEMISTRY
- Tau-Directed Immunotherapy: A Promising Strategy for Treating Alzheimer’s Disease and Other Tauopathies
- (2015) Sulana K. Schroeder et al. Journal of Neuroimmune Pharmacology
- Evidence that the rab5 effector APPL1 mediates APP-βCTF-induced dysfunction of endosomes in Down syndrome and Alzheimer’s disease
- (2015) S Kim et al. MOLECULAR PSYCHIATRY
- Tau Immunotherapy
- (2015) Einar M. Sigurdsson Neurodegenerative Diseases
- Y682G Mutation of Amyloid Precursor Protein Promotes Endo-Lysosomal Dysfunction by Disrupting APP–SorLA Interaction
- (2015) Luca Rosario La Rosa et al. Frontiers in Cellular Neuroscience
- Nerve Growth Factor Gene Therapy
- (2015) Mark H. Tuszynski et al. JAMA Neurology
- The involvement of BDNF, NGF and GDNF in aging and Alzheimer's disease
- (2015) Josiane Budni et al. Aging and Disease
- Pathogenesis of synaptic degeneration in Alzheimer's disease and Lewy body disease
- (2014) Cassia R. Overk et al. BIOCHEMICAL PHARMACOLOGY
- Alzheimer disease: Epidemiology, diagnostic criteria, risk factors and biomarkers
- (2014) Christiane Reitz et al. BIOCHEMICAL PHARMACOLOGY
- Passive immunization targeting the N-terminal projection domain of tau decreases tau pathology and improves cognition in a transgenic mouse model of Alzheimer disease and tauopathies
- (2014) Chun-ling Dai et al. JOURNAL OF NEURAL TRANSMISSION
- Effects of sustained proNGF blockade on attentional capacities in aged rats with compromised cholinergic system
- (2014) B. Yegla et al. NEUROSCIENCE
- Amyloid-β and Tau
- (2014) George S. Bloom JAMA Neurology
- Cholinergic circuitry of the human nucleus basalis and its fate in Alzheimer's disease
- (2013) M.-Marsel Mesulam JOURNAL OF COMPARATIVE NEUROLOGY
- Up-regulation of sortilin mediated by amyloid-β and p75NTR: safety lies in the middle course
- (2013) Elizabeth J. Coulson et al. JOURNAL OF NEUROCHEMISTRY
- Sortilin and SorLA Display Distinct Roles in Processing and Trafficking of Amyloid Precursor Protein
- (2013) C. Gustafsen et al. JOURNAL OF NEUROSCIENCE
- Aβ-independent processes—rethinking preclinical AD
- (2013) Gaël Chételat Nature Reviews Neurology
- Activity-Induced Convergence of APP and BACE-1 in Acidic Microdomains via an Endocytosis-Dependent Pathway
- (2013) Utpal Das et al. NEURON
- Anti-Tau Antibodies that Block Tau Aggregate Seeding In Vitro Markedly Decrease Pathology and Improve Cognition In Vivo
- (2013) Kiran Yanamandra et al. NEURON
- An Intracellular Threonine of Amyloid-β Precursor Protein Mediates Synaptic Plasticity Deficits and Memory Loss
- (2013) Franco Lombino et al. PLoS One
- APP Regulates NGF Receptor Trafficking and NGF-Mediated Neuronal Differentiation and Survival
- (2013) Yun-wu Zhang et al. PLoS One
- Tyr682 in the Aβ-precursor protein intracellular domain regulates synaptic connectivity, cholinergic function, and cognitive performance
- (2012) Carmela Matrone et al. AGING CELL
- Diminished trkA receptor signaling reveals cholinergic-attentional vulnerability of aging
- (2012) Vinay Parikh et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Axonal degeneration in Alzheimer's disease: When signaling abnormalities meet the axonal transport system
- (2012) Nicholas M. Kanaan et al. EXPERIMENTAL NEUROLOGY
- Hippocampal ProNGF Signaling Pathways and β-Amyloid Levels in Mild Cognitive Impairment and Alzheimer Disease
- (2012) Elliott J. Mufson et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Nerve Growth Factor and Alzheimer's Disease: New Facts for an Old Hypothesis
- (2012) Antonino Cattaneo et al. MOLECULAR NEUROBIOLOGY
- Longitudinal measures of cholinergic forebrain atrophy in the transition from healthy aging to Alzheimer's disease
- (2012) Michel Grothe et al. NEUROBIOLOGY OF AGING
- Mild cognitive impairment: pathology and mechanisms
- (2011) Elliott J. Mufson et al. ACTA NEUROPATHOLOGICA
- Atrophy of the Cholinergic Basal Forebrain Over the Adult Age Range and in Early Stages of Alzheimer's Disease
- (2011) Michel Grothe et al. BIOLOGICAL PSYCHIATRY
- APP is Phosphorylated by TrkA and Regulates NGF/TrkA Signaling
- (2011) C. Matrone et al. JOURNAL OF NEUROSCIENCE
- Tau Protein Is Required for Amyloid -Induced Impairment of Hippocampal Long-Term Potentiation
- (2011) O. A. Shipton et al. JOURNAL OF NEUROSCIENCE
- Interaction between NH2-tau fragment and Aβ in Alzheimer's disease mitochondria contributes to the synaptic deterioration
- (2011) Giuseppina Amadoro et al. NEUROBIOLOGY OF AGING
- SORLA/SORL1, a Neuronal Sorting Receptor Implicated in Alzheimer's Disease
- (2011) Thomas E. Willnow et al. REVIEWS IN THE NEUROSCIENCES
- The pathological process underlying Alzheimer’s disease in individuals under thirty
- (2010) Heiko Braak et al. ACTA NEUROPATHOLOGICA
- The cholinergic system, nerve growth factor and the cytoskeleton
- (2010) Grazyna Niewiadomska et al. BEHAVIOURAL BRAIN RESEARCH
- The cholinergic system in aging and neuronal degeneration
- (2010) Reinhard Schliebs et al. BEHAVIOURAL BRAIN RESEARCH
- Proteolytic processing of tau
- (2010) Yipeng Wang et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models
- (2010) Lars M. Ittner et al. CELL
- Does the term ‘trophic’ actually mean anti-amyloidogenic? The case of NGF
- (2010) P Calissano et al. CELL DEATH AND DIFFERENTIATION
- Nerve growth factor as a paradigm of neurotrophins related to Alzheimer's disease
- (2010) P. Calissano et al. Developmental Neurobiology
- Neurotrophic factors in Alzheimer’s disease: role of axonal transport
- (2010) K. Schindowski et al. GENES BRAIN AND BEHAVIOR
- ProNGF Induces PTEN via p75NTR to Suppress Trk-Mediated Survival Signaling in Brain Neurons
- (2010) W. Song et al. JOURNAL OF NEUROSCIENCE
- Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling
- (2010) Christian B Vaegter et al. NATURE NEUROSCIENCE
- Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration
- (2010) Brian R. Hoover et al. NEURON
- Preservation of cortical sortilin protein levels in MCI and Alzheimer's disease
- (2010) Elliott J. Mufson et al. NEUROSCIENCE LETTERS
- Tau Reduction Prevents Aβ-Induced Defects in Axonal Transport: Fig. 1
- (2010) Keith A. Vossel et al. SCIENCE
- Selective vulnerability in Alzheimer's disease: Amyloid precursor protein and p75NTRinteraction
- (2009) Joanna Fombonne et al. ANNALS OF NEUROLOGY
- Interaction of Mint2 with TrkA Is Involved in Regulation of Nerve Growth Factor-induced Neurite Outgrowth
- (2009) Yong Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The interactome of the amyloid β precursor protein family members is shaped by phosphorylation of their intracellular domains
- (2009) Robert Tamayev et al. Molecular Neurodegeneration
- Endogenous Aβ causes cell death via early tau hyperphosphorylation
- (2009) G. Amadoro et al. NEUROBIOLOGY OF AGING
- Neurotoxic and neurotrophic roles of proNGF and the receptor sortilin in the adult and ageing nervous system
- (2008) Raya Al-Shawi et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Cholinergic system during the progression of Alzheimer’s disease: therapeutic implications
- (2008) Elliott J Mufson et al. Expert Review of Neurotherapeutics
- Regulation of Amyloid β-Protein Precursor by Phosphorylation and Protein Interactions
- (2008) Toshiharu Suzuki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- HUMAN PRONGF: BIOLOGICAL EFFECTS AND BINDING PROFILES AT TRKA, P75NTRAND SORTILIN
- (2008) Oliver Clewes et al. JOURNAL OF NEUROCHEMISTRY
- Chronic Exposure to Nerve Growth Factor Increases Acetylcholine and Glutamate Release from Cholinergic Neurons of the Rat Medial Septum and Diagonal Band of Broca via Mechanisms Mediated by p75NTR
- (2008) C. Y. L. Huh et al. JOURNAL OF NEUROSCIENCE
- Identification of a caspase-derived N-terminal tau fragment in cellular and animal Alzheimer's disease models
- (2008) V. Corsetti et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- NGF and BDNF signaling control amyloidogenic route and A production in hippocampal neurons
- (2008) C. Matrone et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started