NGF controls APP cleavage by downregulating APP phosphorylation at Thr668: relevance for Alzheimer's disease

Activation of the Amyloidogenic Route by NGF Deprivation Induces Apoptotic Death in PC12 Cells

(2017) Carmela Matrone et al.   JOURNAL OF ALZHEIMERS DISEASE

Neuronal amyloid-β accumulation within cholinergic basal forebrain in ageing and Alzheimer’s disease

(2015) Alaina Baker-Nigh et al.   BRAIN

Accumulation and age-related elevation of amyloid-β within basal forebrain cholinergic neurons in the rhesus monkey

(2015) D. Norvin et al.   NEUROSCIENCE

Presynaptic c-Jun N-terminal Kinase 2 regulates NMDA receptor-dependent glutamate release

(2015) Robert Nisticò et al.   Scientific Reports

A phase1 study of stereotactic gene delivery of AAV2-NGF for Alzheimer's disease

(2014) Michael S. Rafii et al.   Alzheimers & Dementia

Function, therapeutic potential and cell biology of BACE proteases: current status and future prospects

(2014) Robert Vassar et al.   JOURNAL OF NEUROCHEMISTRY

Axonal BACE1 dynamics and targeting in hippocampal neurons: a role for Rab11 GTPase

(2014) Virginie Buggia-Prévot et al.   Molecular Neurodegeneration

Enhancement of the nonamyloidogenic pathway by exogenous NGF in an Alzheimer transgenic mouse model

(2014) Chang Yang et al.   NEUROPEPTIDES

Activity-Induced Convergence of APP and BACE-1 in Acidic Microdomains via an Endocytosis-Dependent Pathway

(2013) Utpal Das et al.   NEURON

An Intracellular Threonine of Amyloid-β Precursor Protein Mediates Synaptic Plasticity Deficits and Memory Loss

(2013) Franco Lombino et al.   PLoS One

Tyr682 in the Aβ-precursor protein intracellular domain regulates synaptic connectivity, cholinergic function, and cognitive performance

(2012) Carmela Matrone et al.   AGING CELL

Hippocampal ProNGF Signaling Pathways and β-Amyloid Levels in Mild Cognitive Impairment and Alzheimer Disease

(2012) Elliott J. Mufson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Loss of NGF-TrkA Signaling from the CNS Is Not Sufficient to Induce Cognitive Impairments in Young Adult or Intermediate-Aged Mice

(2012) M. Muller et al.   JOURNAL OF NEUROSCIENCE

JNK3 Perpetuates Metabolic Stress Induced by Aβ Peptides

(2012) Sung Ok Yoon et al.   NEURON

c-Jun N-terminal Kinase Regulates Soluble Aβ Oligomers and Cognitive Impairment in AD Mouse Model

(2011) Alessandra Sclip et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

APP is Phosphorylated by TrkA and Regulates NGF/TrkA Signaling

(2011) C. Matrone et al.   JOURNAL OF NEUROSCIENCE

Does the term ‘trophic’ actually mean anti-amyloidogenic? The case of NGF

(2010) P Calissano et al.   CELL DEATH AND DIFFERENTIATION

Stereological quantification of the cerebellum in patients with Alzheimer's disease

(2010) Kjeld Andersen et al.   NEUROBIOLOGY OF AGING

The interactome of the amyloid β precursor protein family members is shaped by phosphorylation of their intracellular domains

(2009) Robert Tamayev et al.   Molecular Neurodegeneration

JNK regulates APP cleavage and degradation in a model of Alzheimer's disease

(2009) Alessio Colombo et al.   NEUROBIOLOGY OF DISEASE

Reduced neuronal co-localisation of nardilysin and the putative α-secretases ADAM10 and ADAM17 in Alzheimer’s disease and Down syndrome brains

(2008) Hans-Gert Bernstein et al.   AGE

Regulation of Amyloid β-Protein Precursor by Phosphorylation and Protein Interactions

(2008) Toshiharu Suzuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NGF and BDNF signaling control amyloidogenic route and A  production in hippocampal neurons

(2008) C. Matrone et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of thr668 in the cytoplasmic domain of the Alzheimer's disease amyloid precursor protein by stress-activated protein kinase 1b (Jun N-terminal kinase-3)

(2003) Claire L. Standen et al.   JOURNAL OF NEUROCHEMISTRY