Article
Biochemistry & Molecular Biology
Yikun Ren, Shanshan Ma, Dan Zhang, Shen Guo, Rong Chang, Yuanmeng He, Minghao Yao, Fangxia Guan
Summary: An injectable hyaluronic acid hydrogel with antioxidative and photothermal antibacterial activity has been developed as a functional dressing for infected wounds. This hydrogel demonstrates good stability, biocompatibility, and effective prevention of early infection and acceleration of wound healing.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Biochemistry & Molecular Biology
Rong Yang, Wenliang Xue, Huiyun Liao, Fubin Wu, Hao Guo, Wenjie Zhang, Penghui Wang, Xiaoyan Tan, Hong Xu, Bo Chi
Summary: A multifunctional hydrogel dressing with antibacterial and antioxidative properties was fabricated to promote skin tissue regeneration and wound healing. The hydrogel possessed tunable gelation time, good tissue adhesiveness, and activity to improve collagen deposition and angiogenesis.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Review
Chemistry, Applied
Bing-De Zheng, Jing Ye, Yu-Cheng Yang, Ya -Yan Huang, Mei-Tian Xiao
Summary: Hydrogels have advantages such as injectability and self-healing, which play an important role in promoting wound healing and inhibiting bacterial growth.
CARBOHYDRATE POLYMERS
(2022)
Article
Engineering, Biomedical
Haotian Tian, Jianqin Yan, Wei Zhang, Huaixu Li, Shouwei Jiang, Haisheng Qian, Xulin Chen, Xingliang Dai, Xianwen Wang
Summary: In recent years, bacterial infection and oxidative stress have posed significant challenges to wound healing. The rise of drug-resistant superbugs has particularly hindered the treatment of infected wounds. The development of new nanomaterials, such as the coordination polymer copper-gallic acid (Cu-GA) nanorods with multi-enzyme activity, has emerged as a promising approach for the treatment of drug-resistant bacterial infections. Cu-GA exhibits enhanced multi-enzyme activity under different pH conditions, effectively killing bacteria in acidic conditions while promoting wound healing in neutral conditions. Furthermore, in vivo studies demonstrate that Cu-GA promotes wound infection healing with good biosafety.
ACTA BIOMATERIALIA
(2023)
Article
Engineering, Multidisciplinary
Jiahui He, Zhenlong Li, Jiaxin Wang, Tongyang Li, Jueying Chen, Xianglong Duan, Baolin Guo
Summary: This study developed a multifunctional hydrogel with antibacterial, antioxidant, self-healing, and conductive properties. The hydrogel is capable of releasing nitric oxide (NO) under near-infrared (NIR) laser irradiation, which promotes the healing of diabetic wounds.
COMPOSITES PART B-ENGINEERING
(2023)
Article
Engineering, Biomedical
Tengfei Ma, Xinyun Zhai, Yongkang Huang, Mengzhen Zhang, Xiaoli Zhao, Yaping Du, Chunhua Yan
Summary: The MoS2-CeO2 nanocomposite combines antibacterial and antioxidant properties, demonstrating excellent PTT antibacterial capability through 808 nm laser treatment, reducing the risk of infection in chronic wounds, especially diabetic ulcer wounds.
ADVANCED HEALTHCARE MATERIALS
(2021)
Article
Chemistry, Applied
Pengpeng Deng, Juanjuan Chen, Lichao Yao, Pingan Zhang, Jinping Zhou
Summary: This study synthesized water-soluble thymine-modified chitosan derivatives with broad-spectrum antibacterial activities against various bacteria and fungi, along with excellent biocompatibility and blood compatibility. TC sponges were found to significantly accelerate the wound healing process, reduce the number of inflammatory cells, and promote the regeneration of epithelial tissue, collagen deposition, and new blood vessel formation.
CARBOHYDRATE POLYMERS
(2021)
Article
Chemistry, Physical
Valamla Bhavana, Padakanti Sandeep Chary, Naveen Rajana, Geetanjali Devabattula, Shashikanta Sau, Chandraiah Godugu, Nitin Pal Kalia, Shashi Bala Singh, Neelesh Kumar Mehra
Summary: The study aimed to formulate and optimize the ferulic acid loaded lemongrass oil nanoemulsion using phase inversion composition method and Box Behnken design. The optimized nanoemulsion exhibited good stability and potential for therapeutic applications. The nanoemulgel developed using the optimized nanoemulsion showed antioxidant and antibacterial activity, and demonstrated excellent wound healing efficacy in vivo.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Engineering, Environmental
Chengyuan Sun, Xuelian Zeng, Shihang Zheng, Yulan Wang, Zhiyu Li, Haining Zhang, Lanlan Nie, Yufeng Zhang, Yanbing Zhao, Xiangliang Yang
Summary: The study successfully prepared CS-GA hydrogels with excellent antioxidant properties and confirmed their ability to form cross-linked hydrogels under physiological conditions, as well as their potential applications in wound healing and hemostasis.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Chemistry, Applied
Yajie Zhong, Farzad Seidi, Yilin Wang, Ling Zheng, Yongcan Jin, Huining Xiao
Summary: An injectable self-healing hydrogel with inherent antibacterial activity was developed by forming dynamic covalent bonds between boronic acid and catechol groups in quaternized chitosan, along with encapsulating EGCG. The hydrogels showed excellent dual functions of antibacterial and antioxidant properties, and demonstrated good biocompatibility and contact-active antibacterial activity. In vivo evaluation showed the hydrogels' regenerative wound healing performance, highlighting their potential as novel wound dressings for wound management.
CARBOHYDRATE POLYMERS
(2022)
Article
Nanoscience & Nanotechnology
Shen Guo, Yikun Ren, Rong Chang, Yuanmeng He, Dan Zhang, Fangxia Guan, Minghao Yao
Summary: An injectable hydrogel material with excellent injectability, self-healing ability, and tissue-adhesiveness was designed and fabricated. It showed antioxidative, antibacterial, and hemostatic abilities, and could effectively stop bleeding and promote wound healing.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Biochemistry & Molecular Biology
Zhendong Guo, Lisi Yan, Bo Zhou, Peiwen Zhao, Wenyuan Wang, Siyan Dong, Bo Cheng, Jing Yang, Xinyu Wang, Binbin Li
Summary: Bacterial infection and excessive reactive oxygen species (ROS) in diabetic wounds can lead to chronic wounds. A hydrogel was developed by combining methacrylated silk fibroin (SFMA) with ε-polylysine (EPL) and manganese dioxide nanoparticles (BMNPs) to improve the wound microenvironment. The hydrogel showed antibacterial and antioxidant properties. In vivo experiments demonstrated that the hydrogel had better antibacterial effects and reduced ROS levels in diabetic wounds infected with Staphylococcus aureus (S. aureus). The hydrogel also promoted wound healing and tissue regeneration.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Engineering, Multidisciplinary
Dan Liu, Jiajun Qiu, Ru Xu, Junyu Liu, Jiayin Feng, Liping Ouyang, Shi Qian, Yuqin Qiao, Xuanyong Liu
Summary: The BPP hydrogel is a highly stretchable, biocompatible, and antibacterial dressing that exhibits excellent wound closure effectiveness, offering complete protection even in special scenarios. The research demonstrates the potential and clinical applicability of the BPP hydrogel in wound healing.
COMPOSITES PART B-ENGINEERING
(2022)
Article
Biotechnology & Applied Microbiology
Hanqiang Zhao, Youguang Xu, Saisai Wang, Pan Li, Ting Wang, Fang Zhang, Juan Li, Yapei Zhang, Jinlong Ma, Weifen Zhang
Summary: A composite wound nano-dressing has been developed that can inhibit bacterial infection and effectively remove excess biofluids, promoting wound healing in vivo.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Nanoscience & Nanotechnology
Lanlan Wang, Ziqiang Zhao, Jinhua Dong, Dawei Li, Wenhao Dong, Haoxuan Li, Yuqi Zhou, Qingsheng Liu, Bingyao Deng
Summary: Multifunctional hydrogel wound dressings with high adhesive, self-healing, antioxidant, and antibacterial activity were designed and fabricated for treating skin injuries in clinical care.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Biochemistry & Molecular Biology
Imen Trabelsi, Naourez Ktari, Mehdi Triki, Intidhar Bkhairia, Sirine Ben Slima, Sameh Sassi Aydi, Samir Aydi, Asehraou Abdeslam, Riadh Ben Salah
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2018)
Article
Agriculture, Multidisciplinary
Ibtissem Ben Hammouda, Mehdi Triki, Bertrand Matthaeus, Mohamed Bouaziz
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2018)
Article
Food Science & Technology
Sirine Ben Slima, Naourez Ktari, Mehdi Triki, Imen Trabelsi, Asehraou Abdeslam, Hafedh Moussa, Iskandar Makni, Ana Maria Herrero, Francisco Jimenez-Colmenero, Claudia Ruiz-Capillas, Riadh Ben Salah
LWT-FOOD SCIENCE AND TECHNOLOGY
(2018)
Article
Food Science & Technology
Abir Mokni Ghribi, Arnal Ben Amira, Ines Maklouf Gafsi, Massara Lahiani, Marwa Bejar, Mehdi Triki, Ahmed Zouari, Hamadi Attia, Souhail Besbes
Article
Toxicology
Yamina Kadri, Riadh Nciri, Sana Bardaa, Noura Brahmi, Saidi Saber, Abdel Halim Harrath, Waleed Aldahmash, Saleh Alwasel, Mohamed Mohany, Abdelfatteh El Feki, Mohamed Salah Allagui
TOXICOLOGY MECHANISMS AND METHODS
(2019)
Article
Biochemistry & Molecular Biology
Sirine Ben Slima, Imen Trabelsi, Naourez Ktari, Sana Bardaa, Karim Elkaroui, Mohamed Bouaziz, Asehraou Abdeslam, Riadh Ben Salah
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2019)
Article
Agricultural Economics & Policy
Sirine Ben Slima, Naourez Ktari, Mehdi Triki, Imen Trabelsi, Hafedh Moussa, Skandar Makni, Asehraou Abdeslam, Ana Maria Herrero, Francisco Jimenez-Colmenero, Claudia Ruiz-Capillas, Riadh Ben Salah
BRITISH FOOD JOURNAL
(2019)
Article
Polymer Science
Amal Feki, Ibtissem Ben Amara, Sana Bardaa, Sawssan Hajji, Naourez Chabchoub, Rim Kallel, Tahia Boudawara, Slim Zghal, Riadh Ben Salah, Moncef Nasri, Naourez Ktari
EUROPEAN POLYMER JOURNAL
(2019)
Article
Food Science & Technology
Imen Trabelsi, Sirine Ben Slima, Naourez Ktari, Mehdi Triki, Rania Abdehedi, Wafa Abaza, Hafedh Moussa, Asehraou Abdeslam, Riadh Ben Salah
Article
Biochemistry & Molecular Biology
Imen Trabelsi, Sirine Ben Slima, Naourez Ktari, Sana Bardaa, Karim Elkaroui, Asehraou Abdeslam, Riadh Ben Salah
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2020)
Article
Biochemistry & Molecular Biology
Amal Feki, Sana Bardaa, Sawssan Hajji, Naourez Ktari, Marwa Hamdi, Naourez Chabchoub, Rim Kallel, Tahia Boudawara, Moncef Nasri, Ibtissem Ben Amara
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2020)
Article
Food Science & Technology
Ahmed Zouari, Pierre Schuck, Frederic Gaucheron, Mehdi Triki, Guillaume Delaplace, Claire Gauzelin-Gaiani, Christelle Lopez, Hamadi Attia, Mohamed Ali Ayadi
LWT-FOOD SCIENCE AND TECHNOLOGY
(2020)
Article
Materials Science, Biomaterials
Marwa Hamdi, Amal Feki, Sana Bardaa, Suming Li, Sakthivel Nagarajan, Manel Mellouli, Tahia Boudawara, Zouheir Sahnoun, Moncef Nasri, Rim Nasri
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2020)
Article
Biotechnology & Applied Microbiology
Sana Bardaa, Mouna Turki, Sameh Ben Khedir, Massara Mzid, Tarek Rebai, Fatma Ayadi, Zouheir Sahnoun
BIOMED RESEARCH INTERNATIONAL
(2020)
Article
Food Science & Technology
Mehdi Triki, Ana M. Herrero, Francisco Jimenez-Colmenero, Claudia Ruiz-Capillas
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
